This table contains a list of x-ray crystal structures available from the Protein Data Bank of standard mechanism canonical inhibitors, either free or in complex with serine proteinases. To explore a given structure further, please click on the link the the PDB datafile.
| Kazal Inhibitor Family | Enzyme | PDB file |
| OMJPQ3 | 1ovo | |
| OMJPQ (modified) | 3ovo | |
| OMSVP3 | 2ovo | |
| OMSVP (modified) | 4ovo | |
| OMTKY3 | Chymotrypsin | 1cho |
| P1(K)-OMTKY3 | Chymotrypsin | 1hja |
| OMTKY3 | Human Leukoyte Elastase | 1ppf |
| OMTKY3 (long) | Strept. Grieus Prot. B | 3sgb |
| P1(G)-OMTKY3 | Strept. Grieus Prot. B | 1sgq |
| P1(A)-OMTKY3 | Strept. Grieus Prot. B | 1sgp |
| OMTKY3 (short) | Strept. Grieus Prot. B | 1sgr |
| PSTI (variant 3) | 1hpt | |
| PSTI (variant 3) | Chymotrypsinogen | 1cgi |
| PSTI (variant 2) | Chymotrypsinogen | 1cgj |
| PSTI (porcine) | Trypsinogen | 1tgs |
| Rhodniin (Insect derived Kazal) (hydrolyzed) | Thrombin | 1tbq |
| Rhodniin (Insect derived Kazal) (hydrolyzed) | Thrombin | 1tbr |
| Leech derived Trypase Inhibitor | Porcine Trypsin | 1an1 |
| SSI Inhibitor Family | Enzyme | PDB file |
| SSI | 3ssi | |
| SSI | Subtilsin BPN' | 2sic |
| SSI (M73K) mutant | Subtilisin BPN' | 3sic |
| SSI (M70G, M73K) mutant | Subtilisin BPN' | 5sic |
| Ascaris Inhibitor Famiy | Enzyme | PDB file |
| Ascaris C/E-Inhibitor | Porcine Pancreatic Elastase | 1eai |
| Potato-I Inhibitor Family | Enzyme | PDB file |
| CI-2 (Barley) | 2ci2 | |
| CI-2 (I76V) | 1coa | |
| CI-2 (barley) | Subtilisin Novo (BPN') | 2sni |
| CI-2 (S31A, E33A, E34A) mutant | 1ypa | |
| CI-2 (S31G, E33A, E34A) mutant | 1ypb | |
| CI-2 (E33A, E34A) mutant | 1ypc | |
| CI-2 (Barley) M59P mutant | Alcalase (Subtilisin) | 1a10 |
| CI-2 (Barley) | Alcalase (Subtilisin) | 1a1y |
| Eglin c (hydrolyzed) | 1egp | |
| Eglin c | Chymotrypsin | 1acb |
| Eglin c | Subtilisin Carlsberg | 1cse |
| Eglin c (N-Acetyl) | Subtilisin Carlsberg | 2sec |
| Eglin c (L45R) | Subtilisin Novo (BPN') | 1sbn |
| Eglin c (R53K) mutant | Subtilisin Novo (BPN') | 1sib |
| Eglin c | Thermitase | 1tec |
| Eglin c | Thermitase (5 mM Ca++) | 2tec |
| Eglin c | Therimtae (100 mM Ca++) | 3tec |
| Eglin c | Mesentericopeptidase | 1mee |
| Potato-II Inhibitor Family | Enzyme | PDB file |
| PCI-I | SGPB | 4sgb |
| Kunitz-BPTI Inhibitor Family | Enzyme | PDB file |
| BPTI | 4pti | |
| BPTI (Crystal form II) | 1bpi | |
| BPTI (Crystal form II) | 5pti | |
| BPTI (Crystal form III) | 6pti | |
| BPTI (F22A) mutant | 1bti | |
| BPTI (Y23A) mutant | 1bpt | |
| BPTI (F25A) mutant | 1fan | |
| BPTI (N23G) mutant | 1nag | |
| BPTI (Y35G) mutant | 8pti | |
| BPTI (M52 oxidized) | 9pti | |
| BPTI Basic (C30V,C51A) mutant | 1aal | |
| BPTI (C30A,C51A) mutant | 7pti | |
| BPTI (C5A, C55A) | Rat Trypsin (D189G, G226D) | 1brb |
| BPTI | Trypsinogen | 2tgp |
| BPTI (K15R) mutant | Trypsinogen | 3tpi |
| BPTI + (Ile-Val) dipeptide | Trypsinogen | 3tpi |
| BPTI (2.5 M MgSO4) + (Ile-Val) | Trypsinogen | 2tpi |
| BPTI | Trypsin (beta) | 2ptc |
| BPTI | AnhydroTrypsin | 1tpa |
| BPTI | Rat Trypsin | 3tgi |
| BPTI | Rat Trypsin (S195A) | 3tgj |
| BPTI | Kallikrein A | 2kai |
| BPTI | Chymotrypsin (3 chains) | 1mtn |
| BPTI | Chymotrypsin | 1cbw |
| BPTI | Thrombin | 1bth |
| Alzheimer's APP Kunitz Domain | 1aap | |
| APP Fragment (289-342) | Bovine Trypsin | 1taw |
| Alzheimer's APP Kunitz Domain | Rat Trypsin (D189G, G226D) | 1brc |
| Alzheimer's APP Kunitz Domain | Chymotrypsin | 1ca0 |
| Tissue Factor Path.Inhib. 2nd Kunitz dom. | Porcine Trypsin | 1tfx |
| Bowman-Birk Inhibitor Family | Enzyme | PDB file |
| PI-II (Soybean) Trypsin Inhibitor | 1pi2 | |
| AB-I Trypsin Inhibitor (adzuki bean) | Trypsin | 1tab |
| Winter Pea Chym./Trypsin Inhibitor | 1pbi | |
| Squash Inhibitor Family | Enzyme | PDB file |
| CMTI-I (Squash) | Bovine Trypsin | 1ppe |
| Trypsin Inhibitor (bitter gourd) | Porcine Trypsin | 1mct |
| CMTI-I (Squash) M8L Variant | 1bxj | |
| Ecotin Inhibitor Family | Enzyme | PDB file |
| Ecotin (space group 43 21 2) | 1ecy | |
| Ecotin (space group 21 21 21) | 1ecz | |
| Ecotin | Collagenase (Fiddler crab) | 1azz |
| Ecotin (A86H) | Trypsin (N143H,E151H) | 1slu |
| Ecotin (A86H) + copper | Trypsin (N143H,E151H) | 1slv |
| Ecotin (A86H) + nickel | Trypsin (N143H,E151H) | 1slw |
| Ecotin (A86H) + zinc | Trypsin (N143H,E151H) | 1slx |
| Kunitz-STI Inhibitor Family | Enzyme | PDB file |
| Soybean Trypsin Inhibitor (Kunitz) | 1ba7 | |
| Soybean Trypsin Inhibitor (Kunitz) | 1avu | |
| Soybean Trypsin Inhibitor (ortho) | Porcine Trypsin | 1avw |
| Soybean Trypsin Inhibitor (tetra) | Porcine Trypsin | 1avx |
| Chymotrypsin Inhibitor (Winged bean) WBC-I | 1wbc | |
| Chymotrypsin Inhibitor (Winged bean) WBC-I | 2wbc | |
| Chymotrypsin Inhibitor (Winged bean) WBC-I | 3wbc | |
| Erythrina Trypsin Inhibitor DE-3 | 1tie | |
| Antistasin Inhibitor Family | Enzyme | PDB file |
| AntiStasin (Factor Xa Inhibitor) | 1skz | |
| Hirustasin | Kallekrein | 1hia |
| Chelonianin Inhibitor Family | Enzyme | PDB file |
| Elafin | Porcine Pancreatic Elastase | 1fle |
| Ragi Inhibitor Family | Enzyme | PDB file |
| Trypsin/Amylase RBI Inhibitor (ragi seed) | 1jfo | |
last updated March 2000, Stephen Lu