December 17, 2007

Purdue Research Park company commercializing method to improve early cancer diagnosis

Performing an analysis
Download photo
caption below

The company has just received seed round funding from the Main Street Venture Fund, located in Fort Wayne, Ind., which will allow the company to further develop its diagnostic tests and to proceed with its second phase of clinical trials. Main Street Venture Fund is part of Ruffolo Benson LLC, a private equity firm in Indiana.

MatrixBio was founded by Daniel Raftery, a Purdue University College of Science professor of analytical and physical chemistry and a researcher at the Bindley Bioscience Center in Purdue's Discovery Park.

"Early cancer detection provides more options for treatment and increases the probability of successful therapeutic interventions," Raftery said. "Our goal for MatrixBio is to be a leading provider of metabolite-based testing in the fast-growing diagnostic testing market."

Raftery and his co-workers have developed an advanced "metabolite profiling" technology that provides highly accurate tests for early cancer diagnosis and potentially for quickly determining the effectiveness of drug treatments.

"We use a combination of powerful analytical methods that we believe can detect cancer at its earliest stages," said Raftery, who initiated his company through the Burton D. Morgan's Innovation Realization Laboratory. "The procedure is noninvasive, accurate and reliable in identifying biomarkers for early cancer diagnoses."

Researchers at MatrixBio will analyze multiple small-molecule metabolite biomarkers that are present in blood and urine. These biomarkers are detected sensitively and quantitatively to provide high test accuracy, Raftery said. The combined use of several metabolite biomarkers is used to diagnose cancer at its earliest stages, which provides more options for effective therapy.

Raftery's company also was one of three companies selected in March during the Fundraising Boot Camp at Purdue's Discovery Park to present before Silicon Valley venture capital firms in California. The other firms, also based on Purdue technology, were M4 Sciences Corp. and BioVitesse Inc.