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| Our research involves the development of new devices and tools for use in the solution of practical problems. The techniques we have used include Raman spectroscopy, fluorescence, thermal lensing, pump-probe and time-correlated-photon-counting, as well as computer simulation and statistical mechanical modeling. Applications of our work range from the development of molecular optical sensors for bio-medical diagnostics to modeling the effects of condensed phase environments on chemical reactions. The light that molecules
emit and scatter may be used not only to study molecular
structure and dynamics, but also to collect data of environmental
and bio-medical importance. For example, we have developed ways
of using molecular spectroscopy to measure temperature, pressure,
viscosity, film thickness and composition as well as
physiologically induced changes and interactions between
biological molecules. We have also developed new hyper-spectral
imaging instruments capable of seeing the distribution of
chemical components in samples such as biological tissue,
pharmaceutical formulations, engineering materials and natural
minerals. By incorporating diode lasers, fiber optics and CCD
array detectors we have obtained high quality Raman spectra and
hyper-spectral images in less than 1 sec - fast enough for
real-time bio-medical diagnostics, industrial process monitoring
and automated recycling applications. |