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LIST OF PUBLICATIONS

 

(108)    Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats

Peng, X. Q.;  Li, X.; Li, J.; Ramachandran, P. V.; Gagare, P. D.; Pratihar, D.; Ashby, C. R.; Gardner, E. L.;  Xi, Z. X. Drug and Alcohol Dependence, 2007, 00, 0000.

 

(107)    Synthesis of (E)- and (Z)-r-Alkylidene-g-aryl-g-butyrolactones via Alkenylalumination of Oxiranes Ramachandran, P. V.; Garner, G.; Pratihar, D. Org. Lett. 2007, 9, 4753-56.

 

(106)    Preparative-scale Synthesis of 3,3,3-Trifluoropropene Oxide.

Ramachandran, P. V.; Padiya, K. J. J. Fluorine Chem. 2007, 128, 1255–59.

 

(105)    Preparation of Ammonia Borane in High Yield and Purity, Methanolysis and Regeneration.

Ramachandran, P. V.; Gagare, P. D. Inorg. Chem. 2007, 46, 7810-17.

  

(104)    Convenient Synthesis of Stable Aldimine-Borane Complexes, Chiral -Amino Alcohols, and g-Substituted GABA Analogs from Nitriles.

Ramachandran, P. V.; Biswas, D. Org. Lett. 2007, 9, 3025-27.

 

(103)    Acidity-Directed Synthesis of Substituted g-Butyrolactones from Aliphatic Aldehydes. 

            Ramachandran, P. V.; Pratihar, D. Org. Lett. 2007, 9, 2087-90.

 

(102)    The Influence of Fluorine on the Asymmetric Reduction of Fluoromethyl Ketones. Ramachandran, P. V.; Gong, B. Q.; Teodorovic, A. V. J. Fluorine Chem. 2007, 128, 844-50.

 

(101)    Asymmetric Hydroboration and Matteson Homologation of for the Preparation of Fluorinated a-Phenethanols.  Ramachandran, P. V.; Jennings, M. P. J. Fluorine Chem. 2007, 128, 827-31.

 

(100)    Total Synthesis of Potential Antitumor Agent, (-)-Dictyostatin, Ramachandran, P. V.; Srivastava, A.; Hazra, D. Org. Lett. 2007, 9, 157-160.

 

(99)      Synthesis of Fluorinated Glutamic Acid Derivatives via Vinylalumination, Ramachandran, P. V.; Madhi, S.; O’Donnell, M. J. J. Fluorine Chem. 2007, 128, 78-83.

 

(98)      Acute and Repeated Administration of Fluoxetine, Citalopram and Paroxetine Significantly Alter the Activity of Midbrain Dopamine Neurons in Rats: An In Vivo Electrophysiological Study,  Sekine, Y.; Suzuki, K.; Ramachandran, P. V. Blackburn, T.; Ashby, C. R.* Synapse, 2007, 61, 72-77.

 

(97)      Heat of reaction measurements of sodium borohydride alcoholysis and hydrolysis. 

Zhang J.; Fisher, T. S*.; Gore, J. P.; Hazra, D.; Ramachandran, P. V.* Int. J. Hydrogen Energy 2006, 31, 2292-98.

 

(96)      Control of Stereochemistry: A General Synthesis of cis- or trans-b,g-Disubstituted-g-butyrolactones following Z-crotylboration, Ramachandran, P. V.; Pratihar, D.; Biswas, D.  Org. Lett. 2006, 8, 3877-80.

 

(95)      Regioselective Hydroboration-oxidation and -amination of Fluoro-substituted Styrenes.  Ramachandran, P. V.; Madhi, S.; O’Donnell, M. J. J. Fluorine Chem. 2006, 127, 1252-55.

 

(94)      Catalytic Enantioselective Synthesis of Glutamic Acid Derivatives via Tandem Conjugate Addition-Elimination of Activated Allylic Acetates under Chiral PTC Conditions.  Ramachandran, P. V.; Madhi, S.; Bland-Berry, L.; Reddy, M. V. R.; O’Donnell, M. J.  J. Am. Chem. Soc. 2005, 127, 13450-51.

 

(93)      Chiral Synthesis of Functionalized Tetrahydropyridines: -Aminobutyric Acid Uptake Inhibitor Analogues.

Ramachandran, P. V.; Burghardt, T. E.; Bland-Berry, L.;  J. Org. Chem., 2005; 70, 7911-7918.

 

(92)      Studies Towards the Synthesis of Epothilone A via Organoboranes. Ramachandran, P. V.; Chandra, J. S; Prabhudas, B.; Pratihar, D.; Reddy, M. V. R..  Org. Biomol. Chem., 2005, 3, 3812 - 3824

 

(91)      Asymmetric Allylboration of a,b-Enals as a Surrogate for the Enantioselective Synthesis of Allylic Amines and α-Amino Acids.  Ramachandran, P. V.; Burghardt, T. V.; Reddy, M. V. R. J. Org. Chem. 2005, 70, 2329-2931.

 

(90)      Synthesis of 4-Substituted Homoallylic Alcohols via a One-pot Tandem Lewis-Acid Catalyzed Crotylboration-[3,3]-Sigmatropic Rearrangement.  Ramachandran, P. V.; Pratihar, D.; Biswas, D.  Chem. Commun. 2005, 1988-1989.

 

(89)      Highly Diastereoselective and Enantioselective Preparation of Homoallylic Amines.  Application for the Synthesis of β-Amino Acids and g-Lactams.  Ramachandran, P. V.; Burghardt, T. V.. Chem. Eur. J. 2005, 4387-4395.

 

(88)      Preparation of N-protected allylic amines and α-methylene-β-amino acids from vinylalumination/Baylis-Hillman products via tandem SN2' substitution-Overman rearrangement.  Ramachandran, P. V.; Burghardt, T. V.; Reddy, M. V. R. Tetrahedron Lett. 2005, 46, 2121-2124.

 

(87)      Stereoselective Synthesis of Hex-2-(E)-en-4-yn-1,6-dioates and E,Z-Muconic Acid Diesters via Organo-catalyzed Self-coupling of Propiolates.  Ramachandran, P. V.; Rudd, M. T..; Reddy, M. V. R. Tetrahedron Lett. 2005, 2547-2549.

(86)      Diastereoselective dihydroxylation and regioselective deoxygenation of dihydropyranones: A novel protocol for the stereoselective synthesis of C1-C8 and C15-C21 subunits of (+)-Discodermolide.  Ramachandran, P. V.*; Prabhudas, B.; Chandra, J. S; Reddy, M. V. R. J. Org. Chem. 2004, 69, 6294-6304.

(85)     Asymmetric synthesis of 6-(2 ',3 ',4 ',5 ',6 '-pentafluorophenyl)-δ-lactones via "allyl"boranes: application for the synthesis of fluorinated analog of key pharmacophore of statin drugs.  Ramachandran, P. V.; Padiya, K. J.; Rauniyar, V.; Reddy, M. V. R.; Brown, H. C.  J. Fluor. Chem. 2004, 125, 615-20. 

(84)      An efficient enantioselective total synthesis of a trifluoromethyl analog of Blastmycinolactol.  Ramachandran, P. V.; Padiya, K. J.; Reddy, M. V. R.; Brown, H. C. J. Fluor. Chem. 2004, 125, 579-83.

(83)      Relationship between the structure and enantioselectivity in the asymmetric reduction of 2',6'-disubstituted acetophenones with DIP-Chloride™. An ab initio study. Ramachandran, P. V.; Gong, B. Q.; Brown, H. C.; Francisco, J. S. Tetrahedron Lett. 2004, 45, 2603-05.

(82)      Novel functionalized trisubstituted allylboronates via Hosomi-Miyaura borylation of functionalized allyl acetates.  Ramachandran, P. V.; Pratihar, D.; Biswas, D.; Srivastava, A.; Reddy, M. V. R. Org. Lett. 2004, 6, 481-84.

(81)      Asymmetric Synthesis of g-Perfluorinated Butyrolactones via Organoboranes. Ramachandran, P. V.; Padiya, K. J.; Rauniyar, V.; Reddy, M. V. R.; Brown, H. C. Tetrahedron Lett. 2004, 45, 1015-17.

(80)      Preparative-Scale Synthesis of Both Antipodes of B-γ,γ-Dimethylallyldiisopinocampheylborane: Application for the Synthesis of C1-C6 Subunit of Epothilone.  Ramachandran, P. V.; Prabhudas, B.; Chandra, J. S.; Reddy, M. V. R.; Brown, H. C. Tetrahedron Lett. 2004, 45, 1011-13.

(79)      Vinylalumination for the Synthesis of Functionalized Allyl Alcohols, Vinylepoxides, and α-Alkylidene-β-hydroxy-γ-lactones. Ramachandran, P. V.; Rudd, M. T.; Burghardt, T. E.; Reddy, M. V. R. J. Org. Chem. 2003, 68, 9310-16.

 

(78)      Synthesis of Chiral Tertiary Homoallylic Alcohols via Chelation Controlled Diastereoselective Nucleophilic Addition on α-Alkoxyketones: Application for the Synthesis of C1-C11 Subunit of 8-epi-Fostriecin. Ramachandran, P. V.; Liu, H.; Reddy, M. V. R.; Brown, H. C. Org. Lett. 2003, 5, 3755-57. 

(77)      Stereoselective synthesis of the C7-C21 segment of epothilone A via asymmetric alkoxyallyl- and crotylboration.  Ramachandran, P. V.; Prabhudas, B.; Pratihar, D.; Chandra, J. S.; Reddy, M. V. R. Tetrahedron Lett. 2003, 44, 3745-48.

(76)      Selective Reductions. 60.  Chemoselective reduction of organyl azides with dichloroborane-dimethyl sulfide.  Salunkhe, A. M.; Ramachandran, P. V.;  Brown, H. C. Tetrahedron 2002, 58, 10059-64.

(75)      Efficient synthesis of B-iododialkyl- and B-alkyldiiodoboranes as their acetonitrile complexes: Application for the enolboration-aldolization of ethyl ketones. Ramachandran,  P. V.; Zou,  M. F.; Brown,  H. C. Helv. Chim. Acta 2002, 85, 3027-32.

 

(74)      Stereoselective Synthesis of (+)-Goniodiol, (-)-Epigoniodiol, and (+)-Deoxygoniopypyrone via Alkoxyallylboration and Ring-Closing Metathesis

            Ramachandran, P. V.; Chandra, J. S.; Reddy, M. V. R. J. Org. Chem. 2002, 67, 7547-50.

 

(73)      Study of Fluorocarbonyls in Baylis-Hillman Reaction

            Reddy, M. V. R.; Rudd, M. T.; Ramachandran, P. V. J. Org. Chem. 2002, 67, 5382-85.

 

(72)      Selective Reductions. 59.  Effective Intramolecular Asymmetric  Reductions of a, b, and g-Keto Acids with Diisopinocampheylborane and Intermolecular Asymmetric Reductions of theCorresponding Esters with B-Chlorodiisopinocampheylborane

            Ramachandran, P. V.; Brown, H. C.; Pitre, S. J. Org. Chem. 2002, 67, 5315-19.

 

(71)      Investigation of the Factors Controlling the Regioselectivity of the Hydroboration of Fluoroolefins

            Ramachandran, P. V.; Jennings, M. P.  Chem. Commun. 2002, 386-87.

 

(70)      An Exceptional Hydroboration of Substituted Fluoroolefins Providing Tertiary Alcohols

            Ramachandran, P. V.; Jennings, M. P.  Org.  Lett. 2001, 3, 3789.

 

(69)      Carbonyl and Olefin Reactivities for the Baylis-Hillman Reaction of Fluorocarbonyls

Ramachandran, P. V.; Reddy, M. V. R.; Rudd, M. T.  Chem. Commun. 2001, 757-58.

 

(68)      Asymmetric Synthesis of Umuravumbolide

Reddy, M. V. R.; Rearick, J. P.; Hoch, N.; Ramachandran, P. V. Org.  Lett. 2001, 3, 19-20.

 

(67)      An Efficient Asymmetric Synthesis of Tarchonanthuslactone

Reddy, M. V. R.; Yucel, A. J.; Ramachandran, P. V.  J. Org. Chem. 2001, 66, 2512-14.

 

(66)      Efficient Intramolecular Asymmetric Reductions of a-, b-, and g-Keto Acids with Diisopinocampheylborane

Ramachandran, P. V.; Brown, H. C.; Pitre, S. Org. Lett. 2001, 3, 17-18.

           

(65)      Asymmetric Allylboration for the Synthesis of b-Hydroxy-d-lactone Unit of Statin Drug Analogs

Reddy, M. V. R.; Brown, H. C.; Ramachandran, P. V.  J. Organometal. Chem. 2001, 624, 239-43.

 

(64)      Highly enantioselective synthesis  of (+)- and (-)-Perfluoroalkyl(aryl) Homoallyl Alcohols

            Kumar, D.; Madhavan, S.; Ramachandran, P. V.; Brown, H. C. Tetrahedron Asym. 2000, 11, 4629-32.

 

(63)      A Facile Synthesis of Perfluoroalkyl Vinyl Iodides and Their Palladium Mediated Cross-Coupling Reactions

Jennings, M. P.; Cork, E. A.; Ramachandran, P. V. J. Org. Chem. 2000, 65, 8763-66.

 

(62)     Asymmetric Synthesis of Goniothalamin, Hexadecanolide, Massoia Lactone, and

Parasorbic Acid via Sequential Allylboration-Esterification-Ring-closing Metathesis Reactions

Ramachandran, P. V.; Reddy, M. V. R.; Brown, H. C. Tetrahedron Lett. 2000, 41, 583-86.

 

(61)     An Efficient Enantioselective Synthesis of Argentilactone

Ramachandran, P. V.; Reddy, M. V. R.; Brown, H. C. J. Ind. Chem. Soc. 1999, 739-42.

 

(60)      Critical Role of Catalysts and Borane in Controlling the Regioselectivity in Rhodium-Catalyzed Hydroboration of Perfluoroalkyl(aryl)ethylenes.

Ramachandran, P. V.; Jennings, M. P.; Brown, H. C. Org. Lett. 1999, 1, 1399-1402.

 

(59)      Efficient Synthesis of Functionalized Vinylepoxides

Ramachandran, P. V.; Krzeminski, M. P. Tetrahedron Lett. 1999, 40, 7879-81.

 

(58)      Efficient Diastereoselective Synthesis of anti-a-Bromo-b-hydroxy-ketones.

Brown, H. C.; Zou, M. F. Ramachandran, P. V. Tetrahedron Lett. 1999, 40, 7875-77.

 

(57)      An Improved Vinylalumination Procedure Replacing HMPA with NMO for the Hydroalumination of a-Acetylenic Esters and Ketones.

Ramachandran, P. V.; Reddy, M. V. R.; Rudd, M. T. Chem. Commun. 1999, 1979-80.

 

(56)      Markovnikov Hydroboration of Perfluoroalkylethylenes

Brown, H. C.; Chen, G. M.; Jennings, M. P.; Ramachandran, P. V. Angew. Chem. Internat. Ed. 1999, 38, 2052-54.

 

(55)      The Critical Importance of Water in the Asymmetric Allylboration of N-Trimethylsilylbenz-aldimines with B-Allyldiisopinocampheylborane.

Chen, G. M.; Ramachandran, P. V.; Brown, H. C. Angew. Chem. Int. Ed. Engl. 1999, 38, 825-26.

 

(54)      B-(2-Azido-2-propenyl)-1,3,2-dioxaborinane: A Novel Reagent for Allylboration

Salunkhe, A. M.; Ramachandran, P. V.; Brown, H. C. Tetrahedron Lett. 1999, 40, 1433-36.

 

(53)      A Facile Synthesis of Chiral w-Allyl and w-Propyllactones Via Asymmetric Allylboration of Formyl Esters with B-Allyldiisopinocampheylborane.

Ramachandran, P. V.; Krzeminski, M. P.; Reddy, M. V.; Brown, H. C. Tetrahedron: Asym. 1999, 10, 11-15.

 

(52)      1,4-Diazabicyclo[2.2.2]octane-Catalyzed Self- and Cross-Condensation of a-Acetylenic Ketones and Esters. 

Ramachandran, P. V.; Rudd, M. T.; Reddy, M. V.  Tetrahedron Lett. 1999, 40, 3819-22.

 

(51)      Vinylalumination of Activated Carbonyl Compounds.

Ramachandran, P. V.; Reddy, M. V.; Rudd, M. T.  Tetrahedron Lett. 1999, 40, 627-30.

 

(50)      Chiral Synthesis Via Organoboranes. 46. An Efficient Preparation of Chiral Pyridino- and Thipheno-18-Crown-6 Ligands from Enantiomerically Pure C2-Symmetric Pyridine- and Thiophenediols.

Chen, G. M.; Brown, H. C.; Ramachandran, P. V. J. Org. Chem. 1999, 64, 721-25.

 

(49)      Vinylalumination of Fluoro-carbonyl Compounds.

Ramachandran, P. V.; Reddy, M. V.; Rudd, M. T.; de Alaniz, J. R. Tetrahedron Lett. 1998, 39, 8791.

 

(48)      Efficient Syntheses of Enantiomerically Pure 1,2-Dicyclohexenyl- and 1,2-Dicyclohexyl-1,2-ethanediol Using B-Cyclohexen-1-yl-diisopinocampheylborane

            Chen, G. M.; Ramachandran, P. V. Tetrahedron: Asym. 1997, 8, 3935.

 

(47)      B,B-Dihaloterpenylboranes for the Diastereoselective Enantioselective Synthesis of Syn-Aldols

            Ramachandran, P. V.; Xu, W. C.; Brown, H. C. Tetrahedron Asym. 1997, 8, 1379.

 

(46)      Efficient Syntheses of 2-Isopinocampheyl- and Related 2-Terpenyl-1,3,2-Dioxaboroles from 1,2-Dicarbonyls and 2-Hydroxy Ketones.  Diastereo- and Enantioselective Aldol Reaction of Enediol Boronates.

            Ramachandran, P. V.; Lu, Z. H.; Brown, H. C.  Tetrahedron Lett. 1997, 38, 2421.

 

(45)      Efficient Synthesis of Enantiomerically Pure C2-Symmetric Diols via the Allylboration of Appropriate Dialdehydes.

            Ramachandran, P. V.; Chen, G. M.; Brown, H. C. Tetrahedron Lett. 1997, 38, 2417.

 

(44)      The Origins of Stereoselectivity in Asymmetric Reductions with Boranes Based on (+)-a-Pinene. 2.  The Geometries of Competing Transition-States and the Nature of the Reaction.  A Semi-empirical Study. 

            Rogic, M. M.; Ramachandran, P. V.; Zinnen, H.; Brown, L. D.; Zheng, M. Tetrahedron Asym. 1997, 8, 1287.

 

(43)      Organoboranes for Synthesis. 18. C­2-Symmetric a,a'-Disubstituted-2,6-Pyridinedimethanols as Catalytic Chiral Ligands for the Enantioselective Nucleophilic Addition of Diethylzinc to Aldehydes.

            Brown, H. C.; Chen, G. M.; Ramachandran, P. V. Chirality 1997, 9, 506.

 

(42)      Rate Enhancing Effect of Hydrogen Chloride and Methanesulfonic Acid on the Intamolecular Asymmetric Reduction of o-Aminoaceto- and -benzophenones with Diisopinocampheylborane.

            Ramachandran, P. V.; Malhotra, S. V.; Brown, H. C. Tetrahedron Lett. 1997, 38, 957.

 

(41)      B,B-Dihaloalkylboranes as Efficient Reagents for the Stereoselective Synthesis of Syn-Aldols

            Ramachandran, P. V.; Xu, W. C.; Brown, H. C. Tetrahedron Lett. 1997, 38, 769.

 

(40)      Efficient Syntheses of 1,2- and 1,3-Diols in High Enantiomeric Excess via the Intramolecular Reduction of the Corresponding Ketoalkyl Diisopinocampheylborinates

            Ramachandran, P. V.; Lu, Z. H.; Brown, H. C.  Tetrahedron Lett. 1997, 38, 761.

 

(39)      Organoboranes for Synthesis. 17. Generality of Hydroboration-Amination for the Conversion of Terpenes into Enantiomerically Pure Terpenylamines.  Their Utility for Gas Chromatographic Analysis of Chiral Carboxylic Acids.

            Brown, H. C.; Malhotra, S. V.; Ramachandran, P. V. Tetrahedron Asym. 1996, 7, 3527.

 

(38)      A General, Efficient, Convenient Synthesis of Bis(terpenyl)haloborane Reagents, Valuable for Asymmetric Synthesis via Organoboranes.

            Dhokte, U. P.; Soundararajan, R.; Ramachandran, P. V.; Brown, H. C. Tetrahedron Lett. 1996, 37, 8345.

 

(37)      Contrasting Steric Effects of the Ketones and Aldehydes in the Reactions of the Diisopinocampheylborinates of Methyl Ketones with Aldehydes.

            Ramachandran, P. V.; Xu, W. C.; Brown, H. C. Tetrahedron Lett. 1996, 37, 4911.

 

(36)      An Efficient Preparation of Optically Pure C2-Symmetric Aromatic Diols by the Asymmetric Reduction of Diacylaromatic Compounds with B-Chlorodiisopinocampheylborane.

            Ramachandran, P. V.; Chen, G. M.; Lu, Z. H.; Brown, H. C. Tetrahedron Lett. 1996, 37, 3795.

 

(35)       B-iso-2-(2-diethylaminoethyl)apopinocampheyl-9-borabicyclo[3.3.1]nonyl Hydride – An Improved Chiral Reducing Agent For Straight Chain Aliphatic Ketones.

            Ramachandran, P. V.; Weissman, S. A.  Tetrahedron Lett. 1996, 37, 3791.

 

(34)      Efficient General Asymmetric Syntheses of 3-Substituted 1(3H)-Isobenzofuranones in Very High Enantiomeric Excess.

Ramachandran, P. V.; Chen, G. M.; Brown, H. C. Tetrahedron Lett. 1996, 37, 2205.

 

(33)      The Effect of the Acute and Chronic Administration of (±)-Fluoxetine on Extracellular DA level in the Nucleus Accumbens and Caudate-Putamen: An In Vivo Microanalysis Study.

            Clark, R. N.; Ashby, Jr. C. R.; Ramachandran, P. V.; Dewey, S. L.; Strecker, R. E. Synapse 1996, 23, 125.

 

(32)      Organoboranes for Synthesis. 16.  A Convenient Synthesis of Enantiomerically Pure Isopinocampheylamine, Chiral Derivatizing Agent for Gas Chromatographic Analysis of Optically Active Carboxylic Acids.

            Ramachandran, P. V.; Rangaishenvi, M. V.; Singaram, B.; Goralski, C.; Brown, H. C.  J. Org. Chem. 1996, 61, 341.

 

(31)      Chiral Synthesis via Organoboranes. 43.  Selective Reductions. 58.  Reagent-Controlled Diastereoselctive Reduction of (+)- and (–)-a-Chiral Ketones with (+)- and (–)-B-Chloro-diisopinocampheylborane.

            Ramachandran, P. V.; Chen, G. M.; Brown, H. C.  J. Org. Chem. 1996, 61, 95.

 

(30)      Chiral Synthesis via Organoboranes. 42.  Selective Reductions. 57.  Efficient Kinetic Resolution of Representative a-Tertiary Ketones with B-Chlorodiisopinocampheylborane. 

Ramachandran, P. V.; Chen, G. M.; Brown, H. C.  J. Org. Chem. 1996, 61, 88.

 

(29)      Effect of a Chiral 4-Alkyl Substituent in Hallucinogenic Amphetamines.

            Oberlender, R. A.; Ramachandran, P. V.; Johnson, M. P.; Huang, X.; Nichols, D. E.  J. Med. Chem. 1995, 35, 3593.

 

(28)      Selective Reductions. 56.  Exploration of the B-Haloisopinocampheylboranes for Asymmetric Reduction of Ketones.

            Brown, H. C.;  Ramachandran, P. V.;  Chandrasekharan, J.  Heteroatom Chemistry 1995, 6, 117.

 

(27)      Chiral Synthesis via Organoboranes. 41.  The Utility of B-Chlorodiisopinocampheyl-borane for a General Synthesis of Enantiomerically Pure Drugs 

            Ramachandran, P. V.; Gong, B.; Brown, H. C. Chirality 1995, 7, 103.

 

(26)      Chiral Synthesis via Organoboranes. 40.  Selective Reductions. 55.  A Simple One-pot Synthesis of the Enantiomers of Trifluoromethyloxirane.  A General Synthesis in High Optical Purities of a-Trifluoromethyl sec-Alcohols Via the Ring-cleavage Reactions of the Epoxide.

            Ramachandran, P. V.; Gong, B.; Brown, H. C.  J. Org. Chem. 1995, 60, 41.

 

(25)      Versatile a-Pinene Based Reagents for Asymmetric Synthesis.

            Brown, H. C.; Ramachandran, P. V.  J. Organometal. Chem. 1995, 500, 1.

 

(24)      Selective Reductions. 53.  Asymmetric Reduction of a-Fluoromethyl Ketones with Diisopinocampheylchloroborane and B-Isopinocampheyl-9-borabicyclo[3.3.1]nonane. Combined Electronic and Steric Contributions to the Enantiocontrol Process.

            Ramachandran, P. V.; Teodorovic, A. V.; Gong, B.; Brown, H. C. Tetrahedron: Asym. 1994, 5, 1075.

 

(23)      Selective Reductions. 52.  Efficient Asymmetric Reduction of a-Acetylenic a'-Fluoroalkyl Ketones with Either Diisopinocampheylchloroborane or B-Isopinocampheyl-9-borabicyclo[3.3.1]nonane.  The Influence of Electronic Factors in Reduction.

            Ramachandran, P. V.; Gong, B.; Teodorovic, A. V.; Brown, H. C. Tetrahedron: Asym. 1994, 5, 1061.

 

(22)      A Remarkable Inversion in Configuration of the Product Alcohols from the Asymmetric Reduction of ortho-Hydroxyacetophenones with B-Chlorodiisopinocampheylborane.

            Ramachandran, P. V.; Gong, B.; Brown, H. C. Tetrahedron Lett. 1994, 35, 2141.

 

(21)      Asymmetric Synthesis of Both Enantiomers of a-(4-Fluorophenyl)-4-(2-pyrimidinyl)-1-piperazinebutanol: Potential Antipsychotic Agents

            Ramachandran, P. V.; Gong, B.; Brown, H. C.  Tetrahedron: Asym. 1993, 4, 2399.

 

(20)      Chiral Synthesis via Organoboranes. 38. Selective Reductions. 48.  Asymmetric Reduction of Trifluoromethyl Ketones by B-Chlorodiisopinocampheylborane in High Enantiomeric Purity.

            Ramachandran, P. V.; Teodorovic, A. V.; Brown, H. C.  Tetrahedron 1993, 49, 1725.

 

(19)      Chiral Synthesis via Organoboranes. 34. Selective Reductions. 47. Reduction of Hindered a,b-Acetylenic Ketones to Propargylic Alcohols of Very High Enantiomeric Purity.  Modified Workup procedure to isolate the product alcohols.

            Ramachandran, P. V.; Teodorovic¢, A. V.; Rangaishenvi, M. V.; Brown, H. C. J. Org. Chem., 1992, 57, 5379.

 

(18)      B-Chlorodiiso-2-ethylapopinocampheylborane – An Extremely Efficient Chiral Reducing Agent for Prochiral Ketones of Intermediate Steric Requirements.

            Brown, H. C.; Ramachandran, P. V.; Teodorovic¢, A. V.; Swaminathan, S. Tetrahedron Lett. 1991, 32, 6691.

 

(17)      Selective Reductions. 46.  Effect of the Steric Bulk at the 2-Position of Apopinene on Chiral Reductions.  B-Iso-2-ethyl- and B-Iso-2-n-propylapopinocampheyl-9-borabicyclo-[3.3.1]nonane as Improved Reagents for the Chiral Reduction of a,b-Acetylenic Ketones and a-Keto Esters.

            Brown, H. C.; Ramachandran, P. V.; Weissman, S. A.; Swaminathan, S. J. Org. Chem. 1990, 55, 6328.

 

(16)      Lithium-B-Iso-2-ethylapopinocampheyl-9-borabicyclo[3.3.1]nonyl Hydride as an Improved Reagent for Asymmetric Reduction of Unhindered Aliphatic Ketones.  Further Evidence for the Improved Enantioselectivity in Reductions by Reagents Containing Increased Steric Requirements at the 2-Position of the Apopinene Structure.

            Ramachandran, P. V.; Brown, H. C.; Swaminathan, S. Tetrahedron:  Asymm. 1990, 1, 433.

 

(15)      Hydroboration. 84. Controlled and Sequential Hydroboration of Simple Representative Alkenes with Monoorganylboranes in Tetrahydrofuran.  A Convenient Synthesis of Mixed Borinic Esters, R1R2BOR3 and Mixed Trialkylboranes, R1R2R3B.  An Examination of Positional Selectivity in the First and Second States of Hydroboration.

            Srebnik, M.; Cole, T. E.; Ramachandran, P. V.; Brown, H. C. J. Org. Chem. 1989, 54, 6085.

 

(14)      Selective Reductions. 45. Asymmetric Reduction of Prochiral Ketones by iso-2-Methyl-, iso-2-Ethyl- and iso-2-(2-Benzyloxyethyl)-apopinocampheyl-tert-butylchloroboranes.  Evidence for a Major Influence of the Steric Requirements of the 2-Substituent on the Efficiency of Asymmetric Reduction.

            Brown, H. C.; Ramachandran, P. V. J. Org. Chem. 1989, 54, 4504.

 

(13)      Chiral Synthesis via Organoboranes. 22. Selective Reductions. 44.  The Effect of the Steric Requirements of the Alkyl Substituent in Isopinocampheylalkylchloroboranes for the Asymmetric Reduction of Representative Ketones.

            Brown, H. C.; Srebnik, M.; Ramachandran, P. V. J. Org. Chem. 1989, 54, 1577.

 

(12)      Chiral Synthesis via Organoboranes. 18.  Selective Reductions. 43.  Diisopinocampheyl-chloroborane as an Excellent Chiral Reducing Reagent for the Synthesis of Haloalcohols of High Enantiomeric Purity.  A Highly  Enantioselective synthesis  of Both Optical Isomers of Tomoxetine, Fluoxetine and Nisoxetine.

            Srebnik, M.; Ramachandran, P. V.; Brown, H. C. J. Org. Chem. 1988, 53, 2916.

 

(11)      Chiral Synthesis via Organoboranes. 14.  Selective Reductions. 41.  Diisopinocampheyl-chloroborane, An Exceptionally  Efficient Chiral Reducing Agent.

            Brown, H. C.; Chandrasekharan, J.; Ramachandran, P. V. J. Am. Chem. Soc. 1988, 110, 1539.

 

(10)      Selective Reductions. 40.  A Critical Examination of the Relative Effectiveness of Various Reducing Agents for the Asymmetric Reduction of Different Classes of Ketones.

            Brown, H. C.; Park, W. S.; Cho, B. T.; Ramachandran, P. V. J. Org. Chem. 1987, 52, 5406.

 

(9)        Tomoxetine And The Stereoselectivity of Drug Action.

            Oberlender, R.; Nichols, D. E.; Ramachandran, P. V.; Srebnik, M.  J. Pharm. Pharmacol.  1987, 39, 1055.

 

(8)        Organoboranes. 47. An Extremely Facile Elimination of Alkenes from Dialkylhaloboranes.  A Comparative Rate Study with Related Trialkylboranes.  

            Brown, H. C.; Ramachandran, P. V.; Chandrasekharan, J. Organometallics 1986, 5, 2138.

 

(7)        Highly Efficient Asymmetric Reduction of a-Tertiary Alkyl Ketones with Diisopinocampheylchloroborane.

            Brown, H. C.; Chandrasekharan, J.; Ramachandran, P. V. J. Org. Chem. 1986, 51, 3394.

 

(6)        Hydroboration. 73. Relative Rates of Hydroboration of Representative Heterocyclic Olefins with 9-Borabicyclo[3.3.1]nonane.

            Brown, H. C.; Ramachandran, P. V.; Vara Prasad, J. V. N. J. Org. Chem. 1985, 50, 5583.

 

(5)        Diisopinocampheylchloroborane, A Remarkably Efficient Chiral Reducing Agent for Aromatic Prochiral Ketones.

            Chandrasekharan, J.; Ramachandran, P. V.; Brown, H. C. J. Org. Chem. 1985, 50, 5446.

 

(4)        A Study of the Preparation and Reactions of the Unusually Labile 5-Methyl[1,2,4]oxadiazolo-[2,3- c]quinazolin-2-one.

            Ranganathan, D.; Bamezai, S.; Ramachandran, P. V. Heterocycles 1985, 23, 623.

 

(3)        Iodoxybenzene.  A Remarkably Close Ozone Equivalent.

            Ranganathan, S.; Ranganathan, D.; Ramachandran, P. V. Tetrahedron 1984, 40,  3145.

 

(2)        2-Nitroethyl Phenyl Sulfoxide. A Novel Reagent for Facile Nitroethylene Transfer.

            Ranganathan, D.; Ranganathan, S.; Bamezai, S.; Mehrotra, S.; Ramachandran, P. V. J. Chem. Res. (S). 1983, 78.

 

(1)        A Chemical and Thermochemical Study of Non-Observed Symmetry Allowed Reactions.

            Ranganathan, S.; Ranganathan, D.; Ramachandran, P. V.; Mahanty, M. K.; Bamezai, S. Tetrahedron 1981, 37, 4171.  (Also in R. B. Woodward Remembered: Barton, D. H. R. Ed.; Pergamon Press: Oxford, 1982, pp 509-521).

 

 

Peer-reviewed Proceedings from Conferences, Reviews and Book Chapters

 

(24)      Preparation, Alcoholysis, and Regeneration of Ammonia-Borane, Ramachandran, P. V. Prepr. Pap.-Am. Chem. Soc., Div. Fuel Chem. 2006, 51, 515-16.

 

(23)      Asymmetric Allylboration of N-Metaloimines. 

            Ramachandran, P. V.; Burghardt, T.  Pure Appl. Chem. 2006, 78, 1397-1406.

 

(22)      A Review of Heat Transfer Issues in Hydrogen Storage Technologies by J. Zhang, T.S. Fisher, P.V. Ramachandram, J.P. Gore, I. Mudawar, Int. J. Heat Transfer, 2005, 127, 1391.

 

(21)      “Pinacolborane”, Ramachandran, P. V. and Chandra, J. S. in Electronic Encyclopedia of Reagents for Organic Synthesis.  Paquette, L.; Fuchs, P. L.; Crich, D.; Molander, G. Eds. John Wiley and Sons. West Sussex, UK.

 

(20)      “Catecholborane”, Ramachandran, P. V. and Chandra, J. S. in Electronic Encyclopedia of Reagents for Organic Synthesis.  Paquette, L.; Fuchs, P. L.; Crich, D.; Molander, G. Eds. John Wiley and Sons. West Sussex, UK.

 

(19)      “Dichloroborane-Methyl Sulfide”, Ramachandran, P. V. and Chandra, J. S. in Electronic Encyclopedia of Reagents for Organic Synthesis.  Paquette, L.; Fuchs, P. L.; Crich, D.; Molander, G. Eds. John Wiley and Sons. West Sussex, UK.

 

(18)      Tandem allylboration-ring-closing metathesis reactions for the preparation of biologically active molecules. Ramachandran, P. V.; Reddy, M. V. R.; Brown, H. C.  Pure Appl. Chem. 2003, 75, 1263.

 

(17)      Sequential Allylboration-ring-closing Metathesis Reactions for the Preparation of Biologically Active Molecules

Ramachandran, P. V.; Reddy, M. V. R.; Brown, H. C.  in Boron Chemistry at the Beginning of the 21st Century, Bubnov, Y. N. Ed. Nauka Publishing, Moscow, Russia, 2003, 66-78.

 

(16)      Applications of B-“Allyl” Diisopinocampheylboranes for Organic Syntheses.  Ramachandran, P. V.; Reddy, M. V. R.; Brown, H. C. Proc. Ind. Natl. Sci. Acad. A 2002, 68, 465.

 

(15)      Syntheses of Chiral Lactones via Asymmetric Allylboration

Reddy, M. V. R.; Brown, H. C.; Ramachandran, P. V. in Organoboranes for Syntheses ACS Symposium Series # 783, 2001. pp. 220-234.  Ramachandran, P. V.; Brown, H. C. Eds. American Chemical Society, Washington, DC.

 

(14)      Recent Advances in Borane Chemistry

Ramachandran, P. V.; Brown, H. C. in Organoboranes for Syntheses ACS Symposium Series # 783, 2001. pp. 1-17.  Ramachandran, P. V.; Brown, H. C. Eds. American Chemical Society, Washington, DC.

 

(13)      Asymmetric Synthesis of Fluoro-organic Compounds Via Chiral Organoboranes.

Ramachandran, P. V.; Brown, H. C. in Asymmetric Synthesis of Fluoro-organic Compounds ACS Symposium Series # 746, 2000. Ramachandran, P. V. Ed. American Chemical Society, Washington, DC.

 

(12)      Studies Towards the Syntheses of Functionalized, Fluorinated Allyl Alcohols.

Ramachandran, P. V.; Rudd, M. T.; Reddy, M. V.  in Asymmetric Synthesis of Fluoro-organic Compounds ACS Symposium Series #746, 2000. Ramachandran, P. V. Ed. American Chemical Society, Washington, DC.

 

(11)      Asymmetric Reduction of Fluorine-containing Carbonyl Compounds.

Ramachandran, P. V.; Brown, H. C. in "EPC-synthesis of Fluoro-Organic Compounds:  Stereochemical Challenges and Biomedical Targets", Soloshonok, V. A. Ed., John Wiley: Chichester, West Sussex, UK., 1999, Chapter 6, pp. 179-228.

 

(10)      Asymmetric Reductions with Diisopinocampheylborane

            Ramachandran, P. V.; Brown, H. C. in Advances in Boron Chemistry, Siebert, W. Ed. The Royal Society of Chemistry Special Publication, Cambridge, U. K., 1997, p 201-204.

 

(9)        Recent Developments in Our Sixty Year Program on Diborane and Organoboranes for Synthesis

            Brown, H. C.; Ramachandran, P. V. in Advances in Boron Chemistry, Siebert, W. Ed. The Royal Society of Chemistry Special Publication, Cambridge, U. K., 1997, p 151-162.

 

(8)        Recent Advances in Asymmetric Reductions with B-Chlorodiisopinocampheylborane.

            Ramachandran, P. V.; Brown, H. C. in Reductions in Organic Synthesis, Abdel-Magid, A. F. Ed. American Chemical Society Symposium Series #641, Washington, DC.  1996, pp 84-97.

 

(7)        Sixty Years of Hydride Reductions.

            Brown, H. C.; Ramachandran, P. V. in Reductions in Organic Synthesis, Abdel-Magid, A. F. Ed. American Chemical Society Symposium Series #641, Washington, DC.  1996, pp 1-30.

 

(6)        Asymmetric Synthesis Via Chiral Organoboranes Based on a-Pinene.

            Brown, H. C.; Ramachandran, P. V. in Advances in Asymmetric Synthesis, Vol. 1.  Hassner, A. Ed. JAI Press, Greenwich, CT, 1995, pp 144-210.

 

 (5)       Recent Advances in the Boron Route to Asymmetric Synthesis.

            Brown, H. C.; Ramachandran, P. V. in Current Topics in the Chemistry of Boron, Kabalka, G. Ed. The Royal Society of Chemistry Special Publication No. 143, Cambridge, U. K., 1994, pp 125-129.

 

 (4)       An Approach to a General Reagent For Asymmetric Reduction.

            Ramachandran, P. V.; Brown, H. C. in Current Topics in the Chemistry of Boron, Kabalka, G. Ed. The Royal Society of Chemistry Special Publication No. 143, Cambridge, U. K., 1994, pp 101-112.

 

 (3)       Recent Advances in the Boron Route to Asymmetric Synthesis.

            Brown, H. C.; Ramachandran, P. V. Pure and Appl. Chem. 1994, 66, 201.

 

 (2)       Asymmetric Reduction With Chiral Organoboranes Based on a-Pinene.

            Brown, H. C.; Ramachandran, P. V. Acc. Chem. Res. 1992, 25, 16.

 

(1)        The Boron Approach To Asymmetric Synthesis.

            Brown, H. C.; Ramachandran, P. V. Pure and Appl. Chem. 1991, 62, 307.

 

Non-refereed Reviews

 

(4)        Pinane Based Versatile Allylboranes

            Ramachandran, P. V. Aldrichim. Acta. 2002, 35, 19.

 

(3)        Boron NMR as a Tool for Organic Chemistry

Ramachandran, P. V. in Organic Syntheses via Boranes, Vol. 2. Chapter 9.  Aldrich Chemical Company, Milwaukee, WI, 2001. pp. 325-358.

 

(2)        Asymmetric Reductions with Modified Borohydrides

            Ramachandran, P. V The Alembic  1998, 57, 1.

 

(1)        The Utility of Chiral Organoboranes in the Preparation of Optically Active Compounds.

            Srebnik, M.; Ramachandran, P. V. Aldrichim. Acta. 1987, 20, 9.

 

Books Edited

 

(2)        Organoboranes for Syntheses: Current Advances.  ACS Symposium Series # 783, Ramachandran, P. V.; Brown, H. C. Eds. American Chemical Society, Washington, DC, 2001.

 

(1)        Asymmetric Fluoroorganic Chemistry: Synthesis, Applications, and Future Directions. 

ACS Symposium Series # 746, Ramachandran, P. V. Ed. American Chemical Society, Washington, DC 2000.

 

Book Review

 

(1)        Chirality in Industry. Vol. II. Developments in the Manufacture and Applications of Optically Active Compounds.  Collins, A. N.; Sheldrake, G. N.; Crosby, J. Eds.John wiley, Chichester, UK, 1997. J. Am. Chem. Soc. 1998, 120, 4256.