Peptides Sequencing

Selective ion-molecule reactions may be a useful alternative to CAD in gaining structural information on peptides.

• The laser-induced acoustic desorption/chemical ionization (LIAD/CI) approach has the benefit of allowing the examination of neutral peptides by various chemical ionization reactions such as metal cationization, protonation, etc.

- Metal cationization

- Protonation

- CI reagents

Fragmentation of Peptides