Peer-reviewed Publications 

   2008   

12. Ling Tong, Q. Wei, A. Wei, J. X. Cheng, “Gold nanorods as contrast agents for biological imaging: optical properties, surface conjugation, and photothermal effects”, Photochemistry and Phtotobiology, in press.

11. Y. Fu, T. B. Huff, H. W. Wang, H. Wang, J. X. Cheng, “Ex vivo and in vivo imaging of myelin fibers in mouse brain by coherent anti-Stokes Raman scattering  microscopy”, Optics Express, 2008, in press.

10. R. D. Wampler, D. J. Kissick, C. J. Dehen, E. J. Gualtieri, J. L. Grey, H. Wang, D. H. Thompson, J. X. Cheng, G. J. Simpson, “Selective detection of protein crystals by second harmonic microscopy”, Journal of American Chemical Society, 2008,130:14076-7.

9. Han-Wei Wang, Ning Bao, Thuc L. Le, Chang Lu, Ji-Xin Cheng, "Mcrofluidic CARS cytometry", Opt. Express, 2008, 16: 5782-9.

8. T. B. Huff, Y. Shi, Y. Yan, H. Wang, J. X. Cheng, “Multimodal nonlinear optical microscopy and applications to central nervous system imaging”, IEEE Journal of Selected Topics in Quantum Electronics (invited paper), 2008, 14: 4-9.

7. Y. Fu, T. M. Talavage, J. X. Cheng, "New imaging techniques in the diagnosis of multiple sclerosis", Expert. Opin. Med. Diagn., 2008, 2:1055-1065.

6. Han-Wei Wang, Thuc L. Le, Ji-Xin Cheng, Label-free imaging of arterial cells and extracellular matrix using a multimodal CARS microscope, Opt. Comm., 2008, 281, 1813-1822.

5. Eunah Kang, Haifeng Wang, Il Keun Kwon, Young-Ho Song, Kalpana Kamath, Kathleen M. Miller, James Barry, Ji-Xin Cheng, and Kinam Park^, "Application of coherent anti-Stokes Raman scattering microscopy to image the changes in a paclitaxel-poly(styrene-b-isobutylene-b-styrene) matrix pre and post drug elution", Journal of Biomedical Materials Research Part A, 2008, published online. 

4. Li Li, Ji-Xin Cheng, "Label-Free Coherent Anti-Stokes Raman Scattering Imaging of Coexisting Lipid Domains in Single Bilayers", J. Phys. Chem., 2008, 112,  1576-79.

3. Hongtao Chen, Kim, Li, Wang, Park, Cheng, "Release of Hydrophobic Molecules from Polymer Micelles into Cell Membranes Revealed by Forster Resonance Energy Transfer Imaging", Proc. Natl. Acad. Sci. USA, 2008, 105: 6596-6601. Supplemental.

2. H. Chen, S. Kim, W. He, H. Wang, P. S. Low, K. park, J. X. Cheng, “Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo Forster Resonance Energy Transfer Imaging”, Langmuir, 2008, 24:5213-17. Front Cover Story.

1. Hongtao Chen, Jun Yang, Philip S. Low, Ji-Xin Cheng, "Cholesterol level regulates endosome mobility via Rab proteins", Biophysical Journal, 2008, 94: 1508-1520. Front Cover Story.
 

2007

16. H. Wang, T. B. Huff, Y. Fu, J. X. Cheng, Increasing the imaging depth of coherent anti-Stokes Raman scattering microscopy with a miniature microscope objective, Optics Letters, 2007, 32, 2212-14.

15. We  He, H. Wang, L. C. Hartmann, J. X. Cheng, J. X. & P. S. Low, In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry, Proc. Natl. Acad. Sci. USA, 2007, 104: 11760-65.

14. Ji-Xin Cheng, Coherent Anti-Stokes Raman Scattering Microscopy, Applied Spectroscopy (focal point article), 2007, 91: 197-208.

13. Ling Tong, Yanhui Lu, Robert J. Lee, Ji-Xin Cheng, Imaging receptor mediated endocytosis with a polymeric nanoparticle-based coherent anti-Stokes Raman scattering probe, Journal of Physical Chemistry B, 2007, 111: 9980-85.

12. Y. Fu, H. Wang, R. Shi, J.-X. Cheng. Second harmonic and sum frequency generation imaging of fibrous astroglial filaments in ex vivo spinal tissues, Biophysical Journal, 2007, 92, 3251-3259. cover page story

11. H. Wang, Y. Fu, J. X. Cheng. Experimental Observation and Theoretical Analysis of Raman Resonance Induced Photodamage in Coherent Anti-Stokes Raman Scattering Microscopy, J. Op. Soc. Am. B, 2007, 24, 544-552.

10. J. X. Cheng, H. Wang, T. L. Te, Y. Fu, T. B. Huff, H. W. Wang, Chasing lipids in health and diseases by CARS microscopy. CACS Communications, feature article, Fall 2007.   

9. Yan Fu, Haifeng Wang, Terry B. Huff, Riyi Shi, Ji-Xin Cheng. Coherent Anti-Stokes Raman Scattering Imaging of Myelin Degradation Reveals a Calcium  Dependent Pathway in Lyso-PtdCho Induced Demyelination, Journal of Neuroscience Research, 2007, 85: 2871-2881.

8. T. B. Huff, J. X. Cheng. In vivo coherent anti-Stokes Raman scattering imaging of sciatic nerve tissues, Journal of Microscopy, 2007, 225, 175-182. cover page story

7. Thuc T. Le, Ingeborg M. Langohr, Matthew J. Locker, Michael Sturek, Ji-Xin Cheng, Label-free Molecular Imaging of Atherosclerotic Lesions Using Multimodal Nonlinear Optical Microscopy, Journal of Biomedical Optics, 2007, 12: 054007.

6. T. T.  Le, C. W. Rehrer, T. B. Huff, M. B. Nichols, I. G. Camarillo, J.-X. Cheng. Nonlinear Optical Imaging to Evaluate the Impact of Obesity on Mammary Gland and Tumor Stroma, Molecular Imaging, 2007, 6:205-211.

5. L. Tong, Y. Zhao, T. B. Huff, M. N. Hansen, A. Wei, J. X. Cheng, Gold nanorods mediate tumor cell death by compromising membrane integrity, Advanced Materials, 2007, 19, 3136-41.
 

4. J. Yang, H. Chen, L. R Vlahov, J. -X. Cheng, P. S Low. Characterization of the pH of folate receptor-containing endosomes and the rate of hydrolysis of internalized acid-labile folate drug conjugates, Journal of Pharmacology and Experimental Therapeutics, 2007, 321, 462-468.

3. T. B. Huff, L. Tong, M. Hansen, J. X. Cheng, A. Wei. Hyperthermic effects of gold nanorods on tumor cells, Nanomedicine, 2007, 2, 125-132.

2. T. B. Huff, M. N. Hansen, Y. Zhao, J. X. Cheng. Controlling the Cellular Uptake of Gold Nanorods, Langmuir, 2007, 23, 1596-1599.

1. Eunah Kang, Joshua Robinson, Kinam Park, Ji-Xin Cheng, Paclitaxel distribution in poly(ethylene glycol) / poly(lactide-co-glycolic acid) blends and its release visualized by coherent anti-Stokes Raman scattering microscopy Journal of Controlled Release, Journal of Controlled Release, 2007, 122: 261-268.

2006

5. Y. Fu, H. Wang, R. Shi, J. X. Cheng. Characterization of photodamage in coherent anti-Stokes Raman scattering microscopy, Opt. Express, 2006, 14: 3942-3951.  

4. H. Wang, T. B. Huff, J. X. Cheng. Coherent anti-Stokes Raman scattering imaging with photonic crystal fiber delivered laser source, Opt. Lett., 2006, 31:1417-1419.   

3. E. Kang, H. Wang, Il K. Kwon, K. Park, J. X. Cheng. in situ visualization of paclitaxel distribution and release by coherent anti-Stokes Raman scattering microscopy, Analytical Chemistry, 2006, 78 : 8036-8043.  

2.  Li Li, Ji-Xin Cheng. Coexisting Stripe and Patch-Shaped Gel Domains in Giant Unilamellar Vesicles, Biochemistry, 2006, 45: 11819-11826.
 

1. Jun Yang, Hongtao Chen, Iontcho R. Vlahov, Ji-Xin Cheng, and Philip S. Low. Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging, Proc. Natl. Acad. Sci. USA, 2006, 103: 13872-13877.   

2005

4. H. Wang, Y. Fu, P. Zickmund, R. Shi, J. X. Cheng. Coherent anti-Stokes Raman scattering imaging of live spinal tissues. Biophys. J., 2005, 89:581-591.   

3. L. Li, H. Wang, J. X. Cheng. Quantitative coherent anti-Stokes Raman scattering imaging of lipid distribution in co-existing domains, Biophys. J., 2005, 89:3480-3490.  

2. A. P. Kennedy, J. Sutcliffe, J. X. Cheng. Molecular composition and orientation of myelin figures characterized by coherent anti-Stokes Raman scattering microscopy, Langmuir, 2005, 21:6478-6486.  

1. H. Wang, T. B. Huff, D. A. Zweifel, W. He, P. S. Low, A. Wei, J. X. Cheng. In vitro and in vivo two-photon luminescence imaging of single gold nanorods, Proc. Natl. Acad. Sci. USA, 2005, 102: 15752-15756.     

Book Chapters 

1. X. Xie, J. X. Cheng, and E. O. Potma, “Coherent anti-Stokes Raman scattering microscopy”, in Handbook of Biological Confocal Microscopy, 3rd edition, Edited by J. B. Pawley, Springer, New York, 2006.