Applications:

Papers with Significant Emphasis on Applications:  

Y. Xia, B. A. Thomson, and S. A. McLuckey, Anal. Chem., 79 (2007), 8199-8206.
"Bi-directional Ion Transfer between Quadrupole Arrays: MSn Ion/Ion Reaction Experiments on a Quadrupole/Time-of-Flight Tandem Mass Spectrometer."

J. Liu, X. Liang, and S. A. McLuckey, J. Proteome Res., In Press.
"On the Value of Knowing a z· Ion for What It Is."

 

H. Han, Y. Xia, S.A. McLuckey, J. Proteome. Res., 6 (2007), 3062-3069.
"Ion Trap Collisional Activation of c and z Ions Formed via Gas-Phase Ion/Ion Electron Transfer Dissociation."

 

H. Han, Y. Xia, S.A. McLuckey, Rapid Commun. Mass Spectrom., 12 (2007) 1567-1573.
"Beam-type Collisional Activation of Polypeptide Cations that Survive Ion/Ion Electron Transfer."

J. J. Bowers, J. Liu, H. P. Gunawardena, S. A. McLuckey, J. Mass Spectrom., In Press.
"Protein Identification via Ion Trap Collision-Induced Dissociation and Examination of Low Mass Product Ions."

X. Liang, S. A. McLuckey, J. Am. Soc. Mass Spectrom., 18 (2007) 882-890.
 "Transmission Mode Ion/Ion Proton Transfer Reactions in a Linear Ion Trap."

X. Liang, J. W. Hager, S. A. McLuckey, Anal.Chem., 79 (2007) 3363 - 3370.
"Transmission Mode Ion/Ion Electron Transfer Dissociation in a Linear Ion Trap."

J. Liu, P. A. Chrisman, D. E. Erickson, S. A. McLuckey, Anal. Chem., 79 (2007) 1073-1081.
"Relative Information Content and Top-down Proteomics by Mass Spectrometry:  The Utility of Ion/Ion Proton-transfer Reactions in Electrospray-based Approaches."

 

X. Liang, H. Han, Y. Xia, S. A. McLuckey, J. Am. Soc. Mass Spectrom., 18 (2007) 369-376.
"A Pulsed Triple Ionization Source for Sequential Ion/Ion Reactions in an Electrodynamic Ion Trap."

H. P. Gunawardena, J. F. Emory, S. A. McLuckey, Anal. Chem., 78 (2006) 3788-3793.
"Phosphopeptide Anion Characterization via Sequential Charge Inversion and Electron Transfer Dissociation."

P.A. Chrisman, S.J. Pitteri, S.A. McLuckey, Anal. Chem.,  78 (2006) 310 - 316.
"Parallel Ion Parking of Protein Mixtures."

P.B. O'Connor, J.J. Cournoyer, S.J. Pitteri, P.A. Chrisman S.A. McLuckey, J.Am. Soc. Mass Spectrom., 17 (2006) 15-19.
"Differentiation of Aspartic and Iso-Aspartic Acid Residues in Peptides using Electron Transfer Dissociation."

P.A. Chrisman, S.J. Pitteri, S.A. McLuckey, Anal. Chem., 77 (2005) 3411-3414.
"Parallel Ion Parking: Improving Conversion of Parents to First-Generation Products in Electron Transfer Dissociation."

J.M. Hogan, S.J. Pitteri, P.A. Chrisman, S.A. McLuckey, J. Proteome Res., 4 (2005) 628-632.
"Complementary Structural Information from a Tryptic N-Linked Glycopeptide via Electron Transfer Ion/Ion Reactions and Collision-Induced Dissociation."

P.A. Chrisman, S.J. Pitteri, J.M. Hogan, S.A. McLuckey, J. Am. Soc. Mass Spectrom., 16 (2005) 1020-1030. "SO2-. Electron Transfer Ion/Ion Reactions with Disulfide Linked Polypeptide Ions."

F. Yan, M. He, J.M. Hogan, S.S. Rossie, S.A. McLuckey, J. Mass Spectrom., 40 (2005) 441-451.
"Targeted Biomarker Detection via Whole Protein Ion Trap Tandem Mass Spectrometry:  Thymosin B4 in a Human Lung Cancer Cell Line."

J. Wu, S.A. McLuckey, Int. J. Mass Spectrom., 237 (2004) 197-241.
"Gas-Phase Fragmentation of Oligonucleotide Ions."

P. Pan, H.P. Gunawardena, Y. Xia, S.A. McLuckey, Anal. Chem., 76 (2004) 1165-1174.
"Nano-Electrospray Ionization of Protein Mixtures: Solution pH and Protein pI."

R. Amunugama, J.M. Hogan, K.A. Newton, S.A. McLuckey, Anal. Chem., 76 (2004) 720-727.
"Whole Protein Dissociation in a Quadrupole Ion Trap: Identification of an a priori Unknown Modified Protein."

J.M. Hogan, S.J. Pitteri, S.A. McLuckey, Anal. Chem., 75 (2003) 6509-6516.
"Phosphorylation Site Identification via Ion Trap Tandem Mass Spectrometry of Whole Protein and Peptide Ions: Bovine a-Crystallin A Chain."

P. Pan, S.A. McLuckey, Anal. Chem., 75 (2003) 5468-5474.
"The Effect of Small Cations on the Positive Electrospray Responses of Proteins at Low pH."

P. Pan, S.A. McLuckey, Anal. Chem., 75 (2003) 1491-1499.
"Electrospray Ionization of Protein Mixtures at Low pH."    

G.E. Reid, S.A. McLuckey, J. Mass Spectrom., 37, (2002) 663-675.
"Top Down" Protein Characterization by Tandem Mass Spectrometry."

M. He, G.E. Reid, H. Shang, G.U. Lee, S.A. McLuckey, Anal. Chem., 74 (2002) 4653-4661.
"Dissociation of Multiple Protein Ion Charge States Following a Single Gas-Phase Purification and Concentration Procedure."   

G.E. Reid, H. Shang, J.M. Hogan, G.U. Lee, S.A. McLuckey, J. Am. Chem. Soc., 124, (2002) 7353-7362.
"Gas-Phase Concentration, Purification, and Identification of Whole Proteins from Complex Mixtures."    

S.A. McLuckey, J. Wu, J.L. Bundy, J.L. Stephenson, Jr., G.B. Hurst Anal.Chem., 74 (2002) 976-984.
"Oligonucleotide Mixture Analysis via Electrospray and Ion/Ion Reactions in a Quadrupole Ion Trap."    

J.L. Stephenson, Jr., S.A. McLuckey, G.E. Reid, J.M. Wells, J.L. Bundy Curr. Opin. Biotech., 13 (2002) 57-64.
"The Detection and Identification of Intact Proteins from Complex Mixtures using Ion/Ion Chemistry: Current Status and Future Implications."

G.E. Reid, S.A. McLuckey, J. Mass Spectrom., 37, (2002) 663-675.
"Top Down" Protein Characterization by Tandem Mass Spectrometry."

B.J. Cargile, S.A. McLuckey, and J.L. Stephenson, Jr., Anal. Chem., 74 (2001) 1277-1285.
"Identification of Bacteriophage MS2 Coat Protein from E. Coli Lysates via Ion Trap Collisional Activation of Intact Protein Ions in Conjunction with Ion/Ion Reactions."

J.L. Stephenson, Jr. and S.A. McLuckey, J. Am. Soc. Mass Spectrom., 9 (1998) 585-596.
"Ion/ion Reactions for Oligopeptide Mixture Analysis: Application to Mixtures Comprised of 0.5-100 kDa Components."

J.L. Stephenson, Jr. and S.A. McLuckey, J. Mass Spectrom., 33 (1998) 664-672.
"Charge Manipulation for Improved Mass Determination of High Mass Species and Mixture Components by Electrospray Mass Spectrometry."

S.A. McLuckey, J.L. Stephenson, Jr., and K.G. Asano, Anal. Chem., 70 (1998) 1198-1202.
"Ion/ion Proton Transfer Kinetics: Implications for Analysis of Ions Derived from Electrospray of Protein Mixtures."

J.L. Stephenson, Jr. and S.A. McLuckey, Anal. Chem., 70 (1998) 3533-3544.
"Simplification of Product Ion Spectra Derived from Multiply-Charged Parent Ions via Ion/Ion Chemistry."

M.A. Dearth, K.G. Asano, K.J. Hart, D.E. Goeringer, M.V. Buchanan and S.A. McLuckey Anal. Chem., 69 (1997) 5121-5129.
"Nitric Oxide Chemical Ionization/Ion Trap Mass Spectrometry for the Determination of Hydrocarbons in Engine Exhaust."

J.L. Stephenson, Jr. and S.A. McLuckey Anal. Chem., 68 (1996) 4026-4032.
"Ion/Ion Proton Transfer Reactions for Protein Mixture Analysis."

S.A. McLuckey, L.D. Hulett, Jr., Jun Xu, and T.A. Lewis  Rapid Commun. Mass Spectrom., 10 (1996) 269-276.
"Gas Phase Ionization of Polyatomic Molecules via Interactions with Positrons."

S.A. McLuckey, D.E. Goeringer, K.G. Asano, G. Vaidyanathan, and J.L. Stephenson, Jr.  Rapid Commun. Mass Spectrom., 10 (1996) 287-298.
"High Explosives Vapor Detection by Glow Discharge/Ion Trap Mass Spectrometry."

W.J. Herron, D.E. Goeringer, and S.A. McLuckey Anal. Chem., 68 (1996) 257-262.
"Product Ion Charge State Determination via Ion/Ion Proton Transfer Reactions."

K.G. Asano, D.E. Goeringer and S.A. McLuckey Anal. Chem.,  67 (1995) 2739-2742.
"Parallel Monitoring for Multiple Targeted Compounds by Ion Trap Mass Spectrometry."

M.J. Doktycz; G.B. Hurst, S. Habibi-Goudarzi, S.A. McLuckey, C.H. Chen, K. Tang, M. Uziel, K.B. Jacobson, R.P. Woychik, and M.V. Buchanan Anal. Biochem., 230, (1995) 205-214.
"Analysis of PCR-Amplified DNA Products by Matrix Assisted Laser Desorption and Electrospray Ionization Mass Spectrometry: Current Capabilities and Limitations."

M.J. Doktycz, S. Habibi-Goudarzi, S.A. McLuckey Anal. Chem., 66, (1994) 3416-3422.
"Accumulation and Storage of Ionized Duplex DNA Molecules in a Quadrupole Ion Trap."  

S.A. McLuckey, S. Habibi-Goudarzi J. Am. Soc. Mass Spectrom., 5 (1994) 740-747.
"Ion Trap Tandem Mass Spectrometry Applied to Small Multiply-Charged Oligonucleotides with a Modified Base."

K.J. Hart and S.A. McLuckey J. Am. Soc. Mass Spectrom., 5, (1994) 250-259.
"Relative Dissociation Energy Measurements Using Ion Trap Collisional Activation."

R.S. Ramsey, G.J. Van Berkel, S.A. McLuckey, and G.L. Glish, Biol. Mass Spectrom., 21 (1992) 347.
"Determination of Pyrimidine Cyclobutane Dimers by Electrospray Ionization/Ion Trap Mass Spectrometry."

S.A. McLuckey, G.L. Glish, G.J. Van Berkel, Int. J. Mass Spectrom. Ion Proc., 106 (1991) 213.
"Multiple Stages of Mass Spectrometry in a Quadrupole Ion Trap Mass Spectrometer: Prerequisites."

G.J. Van Berkel, S.A. McLuckey, G.L. Glish, Anal. Chem., 63 (1991) 1098.
"Electrospray Ionization of Porphyrins Using a Quadrupole Ion Trap for Mass Analysis."

S.A. McLuckey, G.L. Glish, and G.J. Van Berkel Anal. Chem., 63 (1991) 1971.
"Charge Determination of Product Ions Formed from Collision-Induced Dissociation of Multiply Protonated Molecules via Ion/Molecule Reactions."

K.B. Jacobson, H.F. Arlinghaus, M.V. Buchanan, R.L. Hettich, G.L. Glish, and S.A. McLuckey Genetic Analysis Techniques and Applications, 8 (1991) 223.
"Applications of Mass Spectrometry to DNA Sequencing."

S.A. McLuckey, B.C. Grant, and G.L. Glish, Anal. Chem., 62 (1990) 56.
"Simultaneous Monitoring for Parent Ions of Specified Daughter Ions: A Method for Rapid Screening Using Mass Spectrometry/Mass Spectrometry."

J.N. Louris, J.S. Brodbelt-Lustig, R.G. Cooks, G.L. Glish, G.J. Van Berkel, and S.A. McLuckey, Int. J. Mass Spectrom. Ion Proc., 96 (1990) 117.
"Sequential Stages of Mass Spectrometry in a Quadrupole Ion Trap Mass Spectrometer."

G.L. Glish, S.A. McLuckey, and K.G. Asano, J. Am. Soc. Mass Spectrom., 1 (1990), 166-173.
"Determination of Daughter Ion Formulas by Multiple Stages of Mass Spectrometry."

G.J. Van Berkel, G.L. Glish, S.A. McLuckey, and A.A. Tuinman, Anal. Chem., 62 (1990) 786.
"Porphyrin Pyrrole Sequencing: Low Energy Collision-Induced Dissociation of (M+7H)+ Generated in situ During Ammonia Chemical Ionization."

G.J. Van Berkel, G.L. Glish, S.A. McLuckey, and A.A. Tuinman, Energy and Fuels, 4 (1990) 720-729.
"High-Pressure Ammonia Chemical Ionization Mass Spectrometry and Mass Spectrometry/Mass Spectrometry for Porphyrin Structure Determination."

G.J. Van Berkel, G.L. Glish and S.A. McLuckey, Org. Geochem., 14 (1989) 203-212.
"Geoporphyrin Structure Determination Using Chemical Ionization Mass Spectrometry/Mass Spectrometry."

S.A. McLuckey, G.L. Glish, K.G. Asano and B.C. Grant, Anal. Chem., 60 (1988) 2220.
"Atmospheric Sampling Glow Discharge Ionization Source for the Analysis of Trace Organics in Ambient Air."

S.A. McLuckey, G.L. Glish and J.A. Carter, J. Forens. Sci., 30 (1985) 773.
"The Analysis of Explosives by Tandem Mass Spectrometry."

E. Schneider, K. Levsen, A.J.H. Boerboom, P. Kistemaker, S.A. McLuckey and M. Przybylski, Anal. Chem., 56 (1984) 1987.
"Identification of Cationic and Anionic Surfactants in Surface Water by Combined Field Desorption-Collisionally Activated Decomposition Mass Spectrometry."

K.L. Busch, G.L. Glish, and S.A. McLuckey, VCH Publishers, New York, 1988.
"Mass Spectrometry/Mass Spectrometry: Techniques and Applications of Tandem Mass Spectrometry"

K. Levsen, E. Schneider, F.W. Rollgen, P. Dahling, A.J.H. Boerboom, P.G. Kistemaker and S.A. McLuckey, in "Analysis of Organic Micropollutants in Water", D. Reidel, Dordrecht, 1984, p.132.
"Mass Spectrometric Identification of Surfactants."