Group Meeting Presentations 2011

Month Week 1 Week 2 Week 3 Week 4 Week 5
January

 

January 2

Happy New Year!
January 9

Ryan
- Paper
"From protein complexes to subunit backbone fragments: a multi-stage approach to native MS"

Nathan- Paper
"Fragmentation of positively-charged biological ions activated with a beam of high-energy cations"
January 16

Zhou
- Research Update

Alice- Paper
"Proteins with highly similar native folds can show vastly dissimilar folding behavior when desolvated"
January 23

Nicole
- Paper
"IRMPD action spectroscopy of alkali metal cation-cytosine complexes: effects of alkali metal cation size on gas phase conformation"

Christine- Paper
"Presentation of a homobifunctional azo-reagent for protein structure analysis by CID chemical cross-linking: proof of principle"
January 30

Stella
- Paper
"Structural characterization of glycerophospholipids by combinations of ozone- and CID-MS: the next step towards "top-down" lipidomics"

Eric- Paper
"A high dynamic range pulse counting detection system for mass spectrometry"
February

 

February 6

Josh
- Paper
"Intercluster reactions show that (CH3)2S+CH2CO2H is a better methyl cation donor than (CH3)3N+CH2CO2H"

Jason-Paper
"Estimation of activation energy from the survival yields: fragmentation study of leucine enkephalin and polyethers by tandem MS"
February 13

Carl
- Paper
"Insights into the binding sites of organometallic ruthenium anticancer compounds on peptides using ultra-high resolution MS"

Will- Paper
"Implementation of dipolar resonant excitation for CID with IM-TOF-MS"
February 20

Corinne
- Research Update
February 27

Ryan
- Paper
"Quantitative MS independence from matrix effects and detector saturation achieved by flow injection analysis with real-time infinite dilution"

Nathan- Paper
"Neutron-encoded mass signatures for quantitative top-down proteomics"
and
"Neutron-encoded mass signatures for multiplexed proteome quantification"
 
March

 

March 6

Zhou
- Paper
"Mass shifting and radical delivery with crown ether attachment for separation and analysis of phosphatidylethanolamine lipids"

Alice- Paper
"Cation-induced stabilization of protein complexes in the gas phase: mechanistic insights from hemoglobin dissociation studies"
March 13

Nicole
- Paper
"Radical additions to aromatic residues in peptides facilitate unexpected side chain and backbone losses"

John- Paper
"Non-direct sequence ions in the tandem MS of protonated peptide amides-an energy-resolved study"
March 20

No Group Meeting
March 27

Eric
- Paper
"Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube IM-MS"

Christine- Paper
"Rapid profiling of laser-induced photochemistry in single microdroplets using MS"
 
April

 

April 3

Stella
- Paper
"Mass selective axial ion ejection from a linear quadrupole ion trap"

Josh- Paper
"Identification of inherently antioxidant regions in proteins with radical-directed dissociation MS"
April 10

Jason
- Paper
"Space charge induced nonlinear effects in quadrupole ion traps"

Will- Orbitrap vs. ICR vs. TOF
"Orbitrap Mass Spectrometry"
April 17

Carl
- Research Update

Corinne- Paper
"Laser electrospray MS minimizes ion suppression facilitating quantitative mass spectral response for multicomponent mixtures of proteins"
April 24

Ryan
- Research Update

Nathan- Paper
"Solution additives for supercharging proteins beyond the theoretical maximum proton-transfer limit in ESI-MS"
 
May

 

May 1

Zhou
- Paper
"Effects of cations on protein and peptide charging in ESI from aqueous solutions"

Alice- Paper
"Separation of protein conformers by differential mobility in hydrogen-rich gases"
May 8

Nicole
- Paper
"Structural characterization of the UV-induced fragmentation products in an ion trap by IRMPD spectroscopy"

John- Paper
"De novo sequencing of peptides using selective 351 nm UVPD MS"
May 15

Christine
- Research Update

Eric- Paper
"Improving the sensitivity of MS by using a new sheath flow electrospray emitter array at subambient pressures"
May 22

Josh
- Research Update

Stella- Paper
"Improved sphingolipidomic approach based on UHPLC and multiple MS with application to cellular neurotoxicity"
May 29

Carl
- Paper
"Direct identification of tyrosine sulfation by using UVPD-MS"

Jason- LaTeX introduction and demonstration
June

 

June 5

Nathan
- Paper
"Insights into the mechanism of protein ESI from salt adduction measurements"
June 12

Prepare for ASMS
June 19

ASMS
June 26

Corinne
- Paper
"DMSO enhances electrospray response, boosting sensitivity of proteomic experiments"

Ryan- How to write a paper
 
July

 

July 3

Zhou
- Paper
"Evidence for ion-ion interactions between peptides and anions (HSO4- or ClO4-) derived from high acidity acids"

Alice- Paper
"Direct analysis of large living organism by megavolt electrostatic ionization MS"
July 10

Nicole
- ASMS Presentations

John
- Paper and ISMS presentation
"Differentiating sulfopeptide and phosphopeptide ions via resonant infrared photodissociation"
July 17

Josh
- Literature Review: Radical Ion Chemistry

Eric- ASMS Presentations
July 24

Christine
- Research Update/ASMS Presentations

Stella- Research Update/ASMS Presentations

July 31

Carl
- Paper
"Diethylpyrocarbonate labeling for the structural analysis of proteins: label scrambling in solution and how to avoid it"

Jason- ASMS Presentation
August

 

August 7

Andrew
- Review of Graduate Research and Oleg's Octopole

Zhou- Paper and ASMS Presentations
"Investigations of the mechanism of the "proline effect" in tandem MS experiments: the "pipecolic acid effect""
August 14

Alice
- Paper
"Mass spectrometric strategies to improve the identification of Pt(II)-modification sites on peptides and proteins"

Corinne- Paper
"Detection of large ions in TOF-MS: effects of ion mass and acceleration voltage on MCP detector response"
August 21

Department Welcome Picnic
August 28

Nicole
- Paper
"Formation of sugar radical cations from CID of non-covalent complexes with S-nitroso thyil radical precursors"

John- Paper
"Comparison of glycopeptide fragmentation by CID and UVPD"
 
September

 

September 4

Eric
- Paper
"A novel multipass oa-TOF mass spectrometer"

Christine
- Paper
"Theta glass capillaries in ESI: rapid mixing and short droplet lifetimes"
September 11

Carl
- Research Update

Josh- Paper
"Ion funnel augmented Mars atmospheric pressure photoionization MS for in situ detection of organic molecules"
September 19

Thesis Interview
September 25

Andrew
- Thesis Research

Corinne- Research Update
 
October

 

October 2

Stella
- Eli Lilly Update

Zhou- Research Update
October 9

Alice
- Research Update

Jason- Paper
"Ion trap electric field characterization using slab coupled optical fiber sensors"
October 16

Nicole
- Paper
"Identification of daughter ions through their electronic spectroscopy at low temperature"

John- Paper
"Action-FRET: Probing the molecular conformation of mass-selected gas-phase peptides with FRET detected by acceptor-specific fragmentation"
October 23

Feifei
- Paper
"Coupling solid-phase microextraction with ambient MS using surface coated wooden-tip probe for rapid analysis of ultra trace perfluorinated compounds in complex samples"

Christine- Paper
"Analyte migration ESI for rapid analysis of complex samples with small volume using MS"
October 30

Eric
- Paper
"Towards miniaturization of TOF-MS: A static voltage linear resonator-like set up for ion packages"

Stella- Paper
"New covalent modifications of phosphatidylethanolamine by alkanals: MS based structural characterization and biological effects"
November

 

November 6

First Year Welcome Talk
November 13

Josh
- Paper
"Comparison of glycopeptide fragmentation by CID and UVPD"

Christine- Practice Turkey Run Presentation
November 20

Carl
- Paper
"The Competitive Influence of Li+, Na+, K+, Ag+ and H+ on the Fragmentation of a PEGylated Polymeric Excipient"

Jason- Paper
" Novel Radio-frequency Quadrupole Ion Trap with Spherical Geometry"
November 27

Happy Thanksgiving!
 
December

 

December 4

Corrine
- Paper
"Desalting protein ions in native mass spectrometry using supercharging reagents"

Andrew- Paper
" Optically detected, single nanoparticle mass spectrometer with pre-filtered electrospray nanoparticle source"
December 11

Nicole
- Paper
"Photodissociation of Conformer-Selected Ubiquitin Ions Reveals Site-Specific Cis/Trans Isomerization of Proline Peptide Bonds"

Alice- Research Update
December 18

Josh- Paper
"A Mass-Spectrometry-Based Framework To Define the Extent of Disorder in Proteins
"

Stella- Paper
" A Novel Route to Recognizing Quaternary Ammonium Cations Using Electrospray Mass Spectrometry
"
December 25

Happy Holidays!