LIST OF PUBLICATIONS BY EI-ICHI NEGISHI

(26) 1. Basic Cleavages of Arylsulfonamides.

Negishi, E.; Day, A. R.

J. Org. Chem. 1965, 30, 43-48.

(60) 2. The Carbonylation of Thexyldialkylboranes. A New General Synthesis of Ketones.

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc. 1967, 89, 5285-5287.

(70) 3. Carbonylation of the Organoboranes from the Cyclic Hydroboration of Dienes with Thexylborane. A Simple

Procedure the Conversion of Dienes into Cyclic Ketones.

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc., 1967, 89, 5477-5478.

(44) 4. Carbonylation of Perhydro-9b-boraphenalene to Form Perhydro-9b-phenalenol. A New General Synthesis of

Polycyclic Derivatives.

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc., 1967, 89, 5478-5480.

(40) 5. A General Stereospecific Annelation for the Synthesis of trans-Fused Polycyclic Ketone via Hydroboration-

Carbonylation

Brown, H. C.; Negishi, E.

Chem. Commun., 1968, 594-595.

(17) 6. Conversion of Linear Trienes into Bicyclic Boranes via Hydroboration-Isomerization and Their Carbonylation. A Simple

Synthesis of Angularly Substituted Bicyclic Alcohols

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc. 1969, 91, 1224-1226.

(4) 7. Reaction of Cyclic Organoboranes from Dienes with Methyl Vinyl Ketone. A Convenient of ω-Hydroxy-ketones from

Dienes via Hydroboration

Suzuki, A.; Nozawa S.; Itoh, M.; Brown, H. C.; Negishi, E.; Gupta, S. K.

Chem. Commun. 1969, 1009-1010.

(25) 8. Organoboranes. IX. Structure of the Organoboranes Formed in the Reaction of 1,3-Butadiene and Diborane in the

Stoichiometric Ratio. An Unusual Thermal Isomerization of the Organoboranes

Brown, H. C.; Negishi, E.; Gupta, S. K.

J. Amer. Chem. Soc. 1970, 92, 2460-2467.

(39) 9. The Reaction of B-Methoxydialkylboranes with Lithium Aluminum Hydride in the Presence of Olefins. A New and

General Synthesis of Acyclic and Cyclic Mixed Trialkylboranes and Their Conversion into the Corresponding

Trialkylcarbinols via Carbonylation-Oxidation

Brown, H. C.; Negishi, E.; Gupta, S. K.

J. Amer. Chem. Soc. 1970, 92, 6648-6649.

(11) 10. A Facile Opening of the Borolane Ring with Borane. A Simple Entry into 12-Tetramethylenediboranes

Brown, H. C.; Negishi, E.; Burke, P. L.

J. Amer. Chem. Soc. 1970, 92, 6649-6651.

(30) 11. A Simple Synthesis of Bisborinane and Its Applicability in Hydroboration for the Preparation of B-Alkylborinanes

Brown, H. C.; Negishi, E.

J. Organometal. Chem. 1971, 26, C67-C69.

(18) 12. A Simple Synthesis of Bis(3,5-dimethyl)borinane and Bis(3,6-dimethyl)borepane as New Valuable Reagents via Cyclic

Hydroboration

Brown, H. C.; Negishi, E.

J. Organometal. Chem. 1971, 28, C1-C4.

(47) 13. A New Four-Carbon-Atom Homologation Involving the Free Radical Chain Reaction of 1,3-Butadiene Monoxide with

Organoboranes. Synthesis of 4-Alkyl-2-buten-1-ols from Olefins via Hydroboration

Suzuki, A.; Miyaura, N.; Itoh, M.; Brown, H. C.; Holland, G. W.; Negishi, E.

J. Amer. Chem. Soc. 1971, 93, 2792-2793.

(16) 14. Organoboranes, XII. Hydroboration of 1,3-Butadiene with Borane in Tetrahydrofuran in a Ratio Equal to or Smaller

than 1:1. Interconversion Between B-Alkylborolane and 1,2-Tetramethylenediboranes.

Brown, H. C.; Negishi, E.; Burke, P. L.

J. Amer. Chem. Soc. 1971, 93, 3400-3409.

(42) 15. The Facile Reaction of B-Alkylboracyclanes with α,β-Unsaturated Carbonyl Derivatives. A Convenient Procedure for

the Transfer of Secondary and Tertiary Alkyl Groups from Boron to Carbon in the 1,4-Addition Reaction

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc. 1971, 93, 3777-3779.

(14) 16. Bisborolane. A Highly Elusive Bisboracyclane

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc. 1971, 93, 6682-6683.

(4) 17. The Cyclic Hydroboration of Dienes. A Simple Convenient Route to Heterocyclic Organoboranes

Brown, H. C.; Negishi, E.

Pure Appl. Chem. 1972, 29, 527-545.

(15) 18. A General Multi-Carbon Homologation of Olefins via Hydroboration-Carbonylation

Negishi, E.; Brown, H. C.

Synthesis 1972, 196-197.

(14) 19. The Reaction of Organoboranes Containing a Tertiary Alkyl Group with Carbon Monoxide. A New Approach to the

Synthesis of Highly Branched Trialkylcarbinols

Negishi, E.; Brown, H. C.

Synthesis 1972, 197-199.

(27) 20. Hydroboration. XXXI. The Cyclic Hydroboration of Dienes with Borane in Tetrahydrofuran in the Molar Ratio of 1:1.

Brown, H. C.; Negishi, E.; Burke, P. L.

J. Amer. Chem. Soc. 1972, 94, 3561-3567.

(39) 21. Hydroboration. XXXII. The Cyclic Hydroboration of Dienes with Thexylboranes

Brown, H. C.; Negishi, E.

J. Amer. Chem. Soc. 1972, 94, 3567-3572.

(26) 22. Monomeric Dialkylboranes

Negishi, E.; Katz, J-J.; Brown, H. C.

J. Amer. Chem. Soc. 1972, 94, 4025-4027.

(16) 23. Remarkably Facile and Selective Dehydroboration of Tetramethylethylene from Thexylmonoalkylboranes under the

Influence of Triethylamine. A Novel, Convenient Synthesis of Monoalkylboranes in Trielethylaminates.

Brown, H. C.; Negishi, E.; Katz, J-J.

J. Amer. Chem. Soc. 1972, 94, 5893-5894.

(20) 24. Hydroboration. XXXIII. The Cyclic Hydroboration of 1,4-Pentadiene with Borane in Tetrahydrofuran. Thermal

Behavior of the Organoborane Derivatives and a Simple Synthesis of Bisborinane and B-Alkylborinanes

Negishi, E; Burke, P. L.; Brown, H. C.

J. Amer. Chem. Soc. 1972, 94, 7431-7437.

(42) 25. Applications of Thexylkylboranes to Stereoselective Synthesis of trans Disubstituted Olefins

Negishi, E.; Katz, J-J.; Brown, H. C.

Synthesis, 1972, 555-556.

(12) 26. Hydroboration. XXXIV. The Cyclic Hydroboration of 1,5-Hexadiene with Borane in Tetrahydrofuran and 9-Borabicycl

(3.3.1)nonane. A New Convenient Route to the Borepane Ring System Utilizing 9-Borabicyclo(3.3.1)nonane

Burke, P. L.; Negishi, E.; Brown, H. C.

J. Amer. Chem. Soc. 1973, 95, 3654-3662.

(63) 27. A Highly Stereoselective and General Synthesis of Conjugated trans, trans-Dienes and trans-Alkenyl Ketones

via Hydroboration.

Negishi, E.; Yoshida, T.

Chem. Commun. 1973, 606-607.

(19) 28. Hydroboration. XXXV. The Cyclic Hydroboration of 2,4-Dimethyl-1,4-pentadiene and 2,5-Dimethyl-1,5-hexadiene.

A Simple Synthesis of Bis(3,5-dimethyl)borinane and Bis(3,6-dimethyl)borepane and Their Application to the 1,4-

Addition Reaction of Organoboranes

Negishi, E.; Brown, H. C.

J. Amer. Chem. Soc. 1973, 95, 6757-6763.

(17) 29. An Intramolecular Michael Reaction Involving Borate Complexes. A Novel Synthesis of β-Hydroxycarboxyic Acids

Negishi, E.; Yoshida, T.

J. Amer. Chem. Soc. 1973, 95, 6837-6838.

(79) 30. Stereoselective Synthesis of Conjugated trans-Enynes Readily Convertible into Conjugated cis, trans-Dienes and its

Application to the Synthesis of the Pheromone Bombykol

Negishi, E.; Lew, G.; Yoshida, T.

Chem. Commun. 1973, 874-875.

(6) 31. Carbonylation of Organoboranes

Negishi, E.

Intra-Science Chem. Reports 1973, 7, 81-94.

(92) 32. Thexylborane-A Highly Versatile Reagent in Organic Synthesis via Hydroboration

Negishi, E.; Brown, H. C.

Synthesis 1974, 77-89.

(19) 33. A Stereoselective Synthesis of Partially Substituted 1,2,3-Butatriene Derivatives via Hydroboration

Yosida, T.; Williams, R. M.; Negishi, E.

J. Amer. Chem. Soc. 1974, 96, 3688-3690.

(17) 34. A Novel Stereoselective Synthesis of (E) and (Z)-α,β-Unsaturated Carboxylic Esters via Hydroboration

Negishi, E.; Lew, G.; Yoshida, T.

J. Org. Chem. 1974, 96, 2321-2322.

(26) 35. A Novel Copper-Containing Hydride Species and its Application to the Reduction of Organic Compounds

Yoshida, T.; Negishi, E.

Chem. Commun. 1974, 762-763.

(25) 36. Novel and Regioselective Aromatic Double Substitution Involving Borate Anions and a Regio- and Stereoselective

Route to Dihydroaromatic Derivatives

Negishi, E.; Merrill, R. E.

Chem. Commun. 1974, 860-861.

(25) 37. Tetrahydrofuran-Promoted Aryl-Alkyl Coupling Involving Organolithium Reagents

Merrill, R. E.; Negishi, E.

J. Org. Chem. 1974, 39, 3452-3453.

(33) 38. A Novel Regio- and Chemoselective Aryl Ketone Synthesis by the Reaction of Arylborate Anions with Aryl Chlorides

Negishi, E.; Abramovitch, A.; Merrill, R. E.

Chem. Commun. 1975, 138-139.

(31) 39. A General One-Carbon Homologation of Organoboranes via α-Thioorganoborate Anions

Negishi, E.; Yoshida, T.; Silveira, A. Jr.; Chiou, B. L.

J. Org. Chem. 1975, 814-816.

(16) 40. Organoboranes and Organoborate Anions - New Classes of Electrophiles and Nucleophiles in Organic Synthesis.

Negishi, E.

J. Chem. Educ. 1975, 52, 159-165.

(40) 41. Hydroboration. XXXVII. The Structural Study of the Hydroboration of Olefins with Thexylborane. A Simple

Synthesis of Thexylmonoalkylboranes

Brown, H. C.; Negishi, E.; Katz, J. J.

J. Amer. Chem. Soc. 1975, 97, 2791-2798.

(16) 42. Hydroboration. XXXVIII. The Structural Study of the Hydroboration of Olefins with Thexylmonoalkylboranes. A

Convenient Route to Thexyldialkylboranes, "Mixed" Dialkyl-boranes and "Mixed" Trialkylboranes

Brown, H. C.; Katz, J. J.; Lanes, C. F.; Negishi, E.

J. Amer. Chem. Soc. 1975, 97, 2799-2804.

(49) 43. An Intermolecular Alkyl-Transfer Reaction of Tetraalkylborate Anions with Acyl Halides. A Novel Method for

Moderating the Carbanion Reactivity

Negishi, E.; Yoshida, T.; Chiu, K. W.

J. Org. Chem. 1975, 40, 1676-1677.

(38) 44. A Steroselctive Synthesis of cis-Alkenylboranes

Negishi, E.; Williams, R. M.; Lew, G.; Yoshida, T.

J. Organometal. Chem., 1975, 92, C4-C6.

(58) 45. A Convenient Method for the Tertiary Alkyl-Alkynyl Coupling via Organoalanes

Negishi, E.; Baba, S.

J. Amer. Chem. Soc., 1975, 97, 7385-7387.

(31) 46. Stereoselective Synthesis of β-Hydroxy Substituted trans-Alkenes by the Reaction of trans-Alkenyltrialkylaluminates

with Epoxides

Negishi, E.; Baba, S.; King, A. O.

J. Chem. Soc. Chem. Commun. 1976, 17-18.

(10) 47. Preparation of Secondary Alcohols by Reaction of Trialkylboranes with Bis(phenylthio)-methyllithium

Hughes, R. J.; Pelter, A.; Smith, K.; Negishi, E.; Yoshida, T.

Tetrahedron Lett. 1976, 87-88.

(79) 48. Chemistry of Organoborates

Negishi, E.

J. Organometal. Chem., 1976, 108, 281-324.

(15) 49. An Efficient Synthesis of Juvabione and Todomatuic Acid via Hydroboration-Carbonylation

Negishi, E.; Sabanski, M.; Katz, J. J.; Brown, H. C.

Tetrahedron 1976, 32, 925-926.

(3) 50. An Unusually Facile Dehydroboration of Triorganoboranes Formed by Treatment of Alkenyltrialkylborates with

Hydrochloric Acid

Chiu, K. W., Negishi, E.; Plante, M. S.; Silveira, A. Jr.

Organometal. Chem. 1976, 112, C3-C6.

(37) 51. A Stereoselective Synthesis of Disubstituted trans-Alkenes by the Reaction of trans-Alkenyltrialkylaluminates with

Alkyl Halides and Sulfonates

Baba, S.; Van Horn, D. E.; Negishi, E.

Tetrahedron Lett. 1976, 1927-1930.

(23) 52. A Novel Intermolecular Transfer Reaction ofAlkenyltrialkylborates with Aqueous Bases and its Application to the

Protonolysis of Alkenylboron Derivatives.

Negishi, E.; Chiu, K. W.

J. Org. Chem. 1976, 41, 3484-3486.

(29) 53. Organoboron and Organoaluminum Compounds as Unique Nucleophiles in Organic Synthesis

Negishi, E.

"New Applications of Organometallics Reagents in Organic Synthesis," Seyferth, D., Ed., Elsevier, Amsterdam, 1976,

93-125.

(62) 54. Novel Stereoselective Alkenyl-Aryl Coupling via Nickel-Catalyzed Reaction of Alkenylalanes with Aryl Halides

Negishi, E.; Baba, S.

J. Chem. Soc. Chem. Comm. 1976, 596-597.

(139) 55. A Novel Stereospecific Alkenyl-Alkenyl Cross-Coupling of a Palladium- orNickel-Catalyzed Reaction of Alkenylalanes

with Alkenyl Halides

Baba, S.; Negishi, E.

J. Amer. Chem. Soc. 1976, 98, 6729-6731.

(8) 56. Organoborane Heterocycles via Cyclic Hydroboration of Dienes

Negishi, E.; Kulkarni, S. U.; Brown, H. C.

Heterocycles 1976, 5, 883-904.

(44) 57. A Highly Efficient Chemo-, Regio-, and Stereoselective Synthesis of (7E,9E)-Dodecadien-1-yl Acetate. A Sex

Pheromone of Lobesia botrana, via A Functionalized Organoborate.

Negishi, E.; Abramovitch, A.

Tetrahedron Lett. 1977, 411-414.

(16) 58. Novel Borate Anion-Assisted Cyclization. Facile Rearrangement of 1-Cyclopropylidene-alkylboranes to

Homopropargylboranes

Merrill, R. E.; Allen, J. L.; Abramovitch, A.; Negishi, E.

Tetrahedron Lett. 1977, 1019-1022.

(428) 59. Selective Carbon-Carbon Bond Formation via Transition Metal Catalysis. 3. A Highly Selective Synthesis of

Unsymmetrical Biaryls and Diarylmethanes by the Nickel- or Palladium-Catalyzed Reaction of Aryl- and Benzylzinc

Derivatives with Aryl Halides

Negishi, E.; King, A. O.; Okudado, N.

J. Org. Chem. 1977, 42, 1821-1823.

(125) 60. Selective Carbon-Carbon Bond Formation via Transition Metal Catalysis. 4. A Novel Approach to Cross-Coupling

Exemplified by the Ni-Catalyzed Reaction of Alkenylzirconium Derivatives with Aryl Halides

Negishi, E.; Van Horn, D. E.

J. Am. Chem. Soc. 1977, 99, 3168-3170.

(15) 61. A Novel Synthesis of an ω-Alkynylorganometallic Reagent via Triple Bond Isomerizationwith with Potassium 3-

Aminopropylamide: ω-Alkynylorganometallic Reagent via Riple Bond Isomerization with Potassium

3-Aminopropylamide: ω-(9-Borabicycl(3.3.1) nonyl)-1-Alkynes

Brown, C. A.; Negishi, E.

J. Chem. Soc. Chem. Comm. 1977, 318-319.

(14) 62. Synthesis of Secondary or Tertiary Alcohols by Reactions of Trialkylboranes with Acyl Carbanion Equivalents

Hughes, R. J.; Ncube, S.; Pelter, A.; Smith, K.; Negishi, E.; Yoshida, T.

J. Chem. Soc., Perkin I, 1977, 1172-1176.

(39) 63. Boraheterocycles via Cyclic Hydroboration

Brown, H. C.; Negishi, E.

Tetrahedron 1977, 33, 2331-2357.

(130) 64. Highly General Stereo-, Regio- and Chemoselective Synthesis of Terminal and Internal Conjugated Enynes by the

Pd-Catalyzed Reactions of Alkynylzinc Reagents with Alkenyl Halides

King, A. O.; Okukado, N.; Negishi, E.

J. Chem. Soc. Chem. Commun. 1977, 683-684.

(175) 65. A General Synthesis of Terminal and Internal Arylalkynes by the Pd-Catalyzed Reaction of Alkynylzinc Reagents with

Aryl Halides

King, A. O; Negishi, E.; Villani, F. J., Jr.; Silveira, A., Jr.

J. Org. Chem. 1978, 43, 358-360.

(94) 66. A Highly Stereo-, Regio-, and Chemoselective Synthesis of Conjugated Dienes by the Palladium-Catalyzed Reaction

of (E)-1-Alkenylzirconium Derivatives with Alkenyl Halides

Okukado, N.; Van Horn, D. E.; Klima, W. L.; Negishi, E.

Tetrahedron Lett. 1978, 1027-1030.

(194) 67. Controlled Carbometallation. The Reaction of Acetylenes with Organoalane-Zirconocene Dichlorides Complexes as a

Route to Stereo- and Regio-Defined Trisubstituted Olefins

Van Horn, D. E.; Negishi, E.

J. Am. Chem. Soc. 1978, 100, 2252-2254.

(216) 68. Double and Multiple Catalysis in the Cross-Coupling Reaction and Its Application to the Stereo- and Regioselective

Synthesis of Trisubstituted Olefins

Negishi, E.; Okukado, N.; King, A. O.; Van Horn, D. E.; Spiegel, B. I.

J. Am. Chem. Soc. 1978, 100, 2254-2256.

(45) 69. Controlled Carbometallation. II. The Addition Reaction of Trimethylalane-Titanocene Dichloride with Acetylenes

Van Horn, D. E.; Valente, L. F.; Idacavage, M. J.; Negishi, E.

J. Organometal. Chem. 1978, 156, C20-C24.

(46) 70. One-Step Conversion of Terminal Acetylenes into Terminally Functionalized. (E)-3-Methyl-2-alkenes via Zirconium-

Catalyzed Carboalumination. A Simple and Selective route to Terpenoids

Okukado, N.; Negishi, E.

Tetrahedron Lett. 1978, 2357-2360.

(30) 71. Scope of the Reaction of Organoborates with Organolithiums as a Method of Preparation of Lithium Organoborates.

Stability of Lithium Organoborates

Negishi, E.; Idacavage, M. J.; Chiu, K. W.; Yoshida, T.; Abramovitch, A.; Goettel, M. E.; Silveira, A., Jr.; Bretherick,

H. D.

J. Chem. Soc., Perkin II. 1978, 1225-1232.

(61) 72. Selective Carbon-Carbon Bond Formation via Transition Metal Catalysis: Is Nickel or Palladium Better than Copper?

Negishi, E.

"Aspects of Mechanism and Organometallic Chemistry," Brewster, J. H., ed., Plenum Press, New York, 1978, 285-317.

(54) 73. A Highly Selective Method for α-Alkylation of Ketones via Potassium Enoxytrialkylborates

Negishi, E.; Idacavage, M. J.; Dipasquale, F.; Silveira, A., Jr.

Tetrahedron Lett. 1979, 845-848.

(64) 74. A Selective Synthesis of (E)-β-Methylalkenyl Iodides via Zirconium-Catalyzed Carboalumination of Terminal

Acetylenes.

Negishi, E.; Van Horn, D. E.; King, A. O.; and Okukado, N.

Synthesis, 1979, 501-502.

(19) 75. NMR Determination of n-Butyllithium.

Silveira, A., Jr.; Bretherick, H. D., Jr.; Negishi, E.

J. Chem. Educ. 1979, 56, 560.

(2) 76. Palladium-Catalyzed Acetylene Syntheses

Negishi, E.

Preprints Petroleum Div. ACS, 1979, 24, 226-232.

(2) 77. Perhydro-9b-boraphenalene and Perhydro-9b-phenalenol

Negishi, E.; Brown, H. C.

Org. Synth., 1983, 61, 103-111.

(432) 78. "Organometallics in Organic Synthesis," Vol. 1, General Discussions and Organometallics of Main Group Metals in

Organic Synthesis

Negishi, E.

Wiley-Interscience, 1980, 532 pp.

(10) 79. Remarkable Countercation Effect in the Reaction of Organoborates with Enolates

Idacavage, M. J.; Negishi, E.; Brown, C. A.

J. Organometal. Chem. 1980, 185, C55-C57.

(110) 80. Conversion of Methyl Ketones into Terminal Acetylenes and (E)-Trisubstituted Olefins of Terpenoid Origin.

Negishi, E.; King, A. O.; Klima, W. L.; Patterson, W.; Silveira, A., Jr.

J. Org. Chem. 1980, 45, 2526-2528.

(162) 81. Palladium-Catalyzed Cross-Coupling Reaction of Homoallylic or Homopropargylic Organozincs with Alkenyl Halides

as a New Selective Route to 1,5-Dienes and 1,5-Enynes

Negishi, E.; Valente, L. F.; Kobayashi, M.

J. Am. Chem. Soc. 1980, 102, 3298-3299.

(66) 82. A Novel Zirconium-Catalzyed Hydroalumination of Olefins

Negishi, E.; Yoshida, T.

Tetrahedron Lett. 1980, 1501-1504.

(38) 83. A Selective and Efficient Synthesis of (E)-4-Methyl-3-alken-1-ols via Zirconium Catalyzed Carboalumination of

Terminal Alkynes

Kobayashi, M.; Valente, L. F.; Negishi, E.; Patterson, W.; Silveira, A., Jr.

Synthesis 1980, 1034-1035.

(92) 84. A Pd-Catalyzed Stereospecific Substitution Reaction of Homoallylzincs with β-Bromo-Substituted α,β-Unsaturated

Carbonyl Derivatives as a Novel Route to Butenoilides and Related Natural Products of Terpenoid Origin. A Highly

Selective Synthesis of Mokupalide

Kobayashi, M.; Negishi, E.

J. Org. Chem. 1980, 45, 5223-5225.

(83) 85. 1,1-Dimetalloalkenes Containing Aluminum as Well as Titanium or Zirconium. Their Structures and Use as Novel

Alkenylidene and Alkenyl Transfer Agents

Yoshida, T.; Negishi, E.

J. Am. Chem. Soc. 1981, 103, 1276-1277.

(94) 86. Palladium-Catalyzed Stereo- and Regiospecific Coupling of Allylic Derivatives with Alkenyl and Arylmetals. A Highly

Selective Synthesis of 1,4-Dienes

Matsushita, H.; Negishi, E.

J. Am. Chem. Soc., 1981, 103, 2882-2884.

(95) 87. A Versatile and Selective Route to Difunctional Trisubstituted (E)-Alkene Synthons via Zirconium-Catalyzed

Carboalumination of Alkynes

Rand, C. L.; Van Horn, D. E.; Moore, M. W.; Negishi, E.

J. Org. Chem. 1981, 46, 4093-4096.

(45) 88. Highly Selected Synthesis of Allylated Arenes and Diarylmethanes via Palladium-Catalyzed Cross Coupling Involving

Benzylic Derivatives

Negishi, E.; Matsushita, H.; Okukado, N.

Tetrahedron Lett. 1981, 22, 2715-2718.

(44) 89. Mechanism of the Zr-Catalyzed Carboalumination of Alkynes. Evidence for Direct Carboalumination

Negishi, E.; Yoshida, T.

J. Am. Chem. Soc. 1981, 103, 4985-4987.

(51) 90. Scope of the Palladium-Catalyzed Coupling Reaction of Organometallics with Allylic Electrophiles. Effect of the

Leaving Group

Negishi, E.; Chatterjee, S.; Matsushita, H.

Tetrahedron Lett. 1981, 22, 3737-3740.

(217) 91. Bimetallic Catalytic Systems Containing Ti, Zr, Ni, and Pd. Their Applications to Selective Organic Syntheses

Negishi, E.

Pure Appl. Chem. 1981, 53, 2333-2356.

(6) 92. Highly Sensitive and Convenient Method for the Synthesis of 1,5-Enynes and 1,5-Dienes by the Reaction of

1,3-Dilithiopropargyl Phenyl Sulfide with Allylic Halides

Negishi, E.; Rand, C. L.; Jadhav, K. P.

J. Org. Chem. 1981, 46, 5041-5044.

(77) 93. Anti Stereospecificity in the Palladium-Catalyzed Reactions of Alkenyl-metal or Aryl-metal Derivatives with Allylic

Electrophiles.

Matsushita, H.; Negishi, E.

J. Chem. Soc. Chem. Commun. 1982, 160-161.

(66) 94. Stereo- and Regioselective Routes to Allylic Silanes

Negishi, E.; Luo, F.-T.; Rand, C. L.

Tetrahedron Lett. 1982, 23, 27-30.

(105) 95. A Regiospecific Synthesis of Carbosubstituted Heteroaromatic Derivatives via Pd-Catalyzed Cross Coupling

Negishi, E.; Luo, F.-T.; Frisbee, R.; Matsushita, H.

Heterocycles, 1982, 18, 117-122.

(7) 96. A Selective Synthesis of Alkenylmercuric Chlorides via Alkenylalanes

Negishi, E.; Jadhav, K. P.; Daotien, N.

Tetrahedron Lett. 1982, 23, 2085-2086.

(20) 97. Selective and Convenient Synthesis of β,β-Disubstituted Alkenylboranes and Alkenylzirconiums via Carboalumination

of Alkynes

Negishi, E.; Boardman, L. D.

Tetrahedron Lett. 1982, 23, 3327-3330.

(56) 98. A Highly Regio- and Stereospecific Palladium-Catalyzed Allylation of Enolates Derived from Ketones

Negishi, E.; Matsushita, H.; Chatterjee, S.; John, R. A.

J. Org. Chem. 1982, 47, 3188-3190.

(1) 99. Bimetallic Reagent Systems Containing a Main Group Metal and a Transition Metal (in Japanese)

Negishi, E.

Kagaku Zokan (in Japanese) No. 96, 49-61

Nozaki, H.; Mukaiyama, T.; Yamamoto, H. eds. Kagaku Dojin, Kyoto, 1982.

(560) 100. Palladium- or Nickel-Catalyzed Cross Coupling. A New Selective Method for Carbon-Carbon Bond Formation

Negishi, E.

Acc. Chem. Res. 1982, 15, 340-348.

(6) 101. General Discussions of the Organoboron Reactions

Negishi, E.

"Comprehensive Organometallic Chemistry", Wilkinson, G. T.; Stone, F. G. A.; Abel, E. W., Eds. Pergamon, Chap. 45.6,

pp. 279-288, 1982.

(42) 102. Aliphatic Organoboron Compounds

Negishi, E.

"Comprehensive Organometallic Chemistry", Wilkinson, G. T.; Stone, F. G. A.; Abel, E. W., Eds. Pergamon, Chap. 45.7,

pp. 289-329, 1982.

(13) 103. Alkenylboron Compounds

Negishi, E.

"Comprehensive Organometallic Chemistry", Wilkinson, G. T.; Stone, F. G. A.; Abel, E. W., Eds. Pergamon, Chap. 45.8,

pp. 331-352, 1982.

(21) 104. Arylboron Compounds

Negishi, E.

"Comprehensive Organometallic Chemistry", Wilkinson, G. T.; Stone, F. G. A.; Abel, E. W., Eds. Pergamon, Chap. 45.9,

pp. 353-368, 1982.

(11) 105. Alkynylboron Compounds

Negishi, E.

"Comprehensive Organometallic Chemistry", Wilkinson, G. T.; Stone, F. G. A.; Abel, E. W., Eds. Pergamon, Chap.

45.10, pp. 369-380, 1982.

(5) 106. Miscellaneous Organoboron Compounds

Negishi, E.

"Comprehensive Organometallic Chemistry", Wilkinson, G. T.; Stone, F. G. A.; Abel, E. W., Eds. Pergamon, Chap.

45.11, pp. 381-396, 1982.

(63) 107. Palladium-Catalyzed Reactions of Allylic Electrophiles with Organo-metallic Reagents. A Regioselective 1,4-Elimination

and Regio- and Stereoselective Reduction of Allylic Derivatives

Matsushita, E., and Negishi, E.

J. Org. Chem. 1982, 47, 4161-4165.

(0) 108. Biomimetic Polyene Cyclization Producing Medium- and Large-Ring Natural Products (in Japanese)

Negishi, E.

Kagaku Zokan (in Japanese) No. 99, p. 115-123, Nozaki, H., ed. Kagaku Dojin, Kyoto, 1983.

(33) 109. Controlled Carbometallation. 15. Zirconium-Promoted Carbozincation of Alkynes

Negishi, E.; Van Horn, D. E.; Yoshida, T.; Rand, C. L.

Organometallics 1983, 2, 563-565.

(40) 110. 1,4- and 1,5-Diketones via Palladium-Catalyzed Allylation of Potassium Enoxyborates

Negishi, E.; Luo, F. T.; Pecora, A. J.; Silveira, A., Jr.

J. Org. Chem. 1983, 2427-2429.

(50) 111. Highly Regioselective Generation of "Thermodynamic" Enolates and Their Direct Characterization by NMR

Negishi, E.; Chatterjee, S.

Tetrahedron Lett. 1983, 24, 1341-1344.

(60) 112. Palladium-Catalyzed Cross-Coupling Reaction of α-Heterosubstituted Alkenylmetals. A Stereoselective Route to

Heterosubstituted Dienes Suitable for the Diels-Alder Reaction

Negishi, E.; Luo, F. T.

J. Org. Chem. 1983, 48, 1560-1562.

(53) 113. Countercation Effects on the Palladium-Catalyzed Allylation of Enolates

Negishi, E.; John, R. A.

J. Org. Chem. 1983, 48, 4098-4102.

(43) 114. Palladium- or Nickel-Catalyzed Cross Coupling Involving Proximally Heterofunctional Reagents

Negishi, E.

"Current Trends in Organo Synthesis", Nozaki, H., ed., Pergamon, 1983, p. 269-280.

(29) 115. A Convenient Synthesis of Unsymmetrical Bibenzyls, Homoallylarenes, and Homopropargylarenes via Palladium-

Catalyzed Cross Coupling

Negishi, E.; Matsushita, H.; Kobayashi, M.; Rand, C. L.

Tetrahedron Lett. 1983, 24, 3823-3824.

(54) 116. Novel Silicon-Promoted Cyclialkylation of Alkenylmetal Derivatives

Negishi, E.; Boardman, L. D.; Tour, J. M.; Sawada, H.; Rand, C. L.

J. Am. Chem Soc., 1983, 105, 6344-6346.

(144) 117. Palladium-Catalyzed Acylation of Organozincs and Other Organometallics as a Convenient Route to Ketones

Negishi, E.; Bagheri, V.; Chatterjee, S.; Luo, F. T.; Miller, J. A.; Stoll, A. T.

Tetrahedron Lett. 1983, 24, 5181-5184.

(105) 118. Novel Syntheses of Silylcyclopentene Derivatives via Regio- and Stereo-selective Allylzincation of Alkynes

Negishi, E.; Miller, J. A.

J. Am. Chem. Soc. 1983, 105, 6761-6763.

(24) 119. A Highly Selective Synthesis of α-Alkylidenetetrahydrofurans and γ-Alkylidenebutyrolactones via Intramolecular

Opening of Epoxysilanes

Luo, F. T.; Negishi, E.

J. Org. Chem. 1983, 48, 5144-5146.

(41) 120. Cyclic Carboalumination of Alkynylsilanes Forming Exocyclic Alkenes

Miller, J. A.; Negishi, E.

Israel J. Chem. 1984, 24, 76-81.

(56) 121. A General Method for the Preparation of Terminal and Internal Conjugated Diynes via the Palladium Catalyzed Cross

Coupling

Negishi, E.; Okukado, N.; Lovich, S. F.; Luo, F. T.

J. Org. Chem. 1984, 49, 2629-2632.

(40) 122. Reaction of Alkenes and Dienes with t-Butylmagnesium Halides and Zirconoene Dihalides. A Convenient Procedure

for Hydrozirconation and a Novel t-Butylzirconation of Conjugated Alkenes

Negishi, E.; Miller, A. J.; Yoshida, T.

Tetrahedron Lett. 1984, 25, 3407-3410.

(14) 123. Palladium-Catalyzed Synthesis of 1,4-Dienes by Allylation of Alkenylalanes: α-Farnesene

Matsushita, H., and Negishi, E.

Org. Synth. 1984, 63, 31-38.

(39) 124. Mechanistic Duality in Cyclialkylation of Alkenylmetal Derivatives

Boardman, L. D.; Bagheri, V.; Sawada, H.; Negishi, E.

J. Am. Chem. Soc. 1984, 106, 6105-6107.

(41) 125. Zirconium-Catalyzed Allylalumination and Benzylalumination of Alkynes

Miller, J. A.; Negishi, E.

Tetrahedron Lett. 1984, 25, 5863-586

(31) 126. Formation of Carbon-Carbon and Carbon-Hetero Atom Bonds via Organo-boranes and Organoborates

Negishi, E., and Idacavage, M. J.

Org. React. 1985, 33, 1-246.

(12) 127. Polycyclic Hydroboration of Acyclic and Cyclic Trienes. Reexamination of the Structures of

Perhydro-9b-boraphenalenes

Brown, H. C.; Negishi, E.; Dickason, W. C.

J. Org. Chem. 1985, 50, 520-527.

(9) 128. Palladium-Catalyzed Cyclization via Intramolecular Allylation of Alkenylmetals

Chatterjee, S.; Negishi, E.

J. Organometal. Chem. 1985, 285, C1-C4.

(19) 129. Palladium-Catalyzed Reaction of Organometals with Allylic Acetals and Orthoesters ad Conjugate Addition Equivalents

Chatterjee, S.; Negishi, E.

J. Org. Chem. 1985, 50, 3406-3408.

(177) 130. Zirconium-Promoted Bicyclization of Enynes

Negishi, E.; Holmes, S. J.; Tour, J. M.; Miller, J. A.

J. Am. Chem. Soc. 1985, 107, 2568-2569.

(18) 131. Palladium-Catalyzed Allylation of Lithium 3-Alkenyl-1-Cyclopentenolates-Triethylborane and Its Application to a

Selective Synthesis of Methyl (Z)-Jasmonate

Luo, F. T.; Negishi, E.

Tetrahedron Letter 1985, 26, 2177-2180.

(111) 132. Organozirconium Compounds as New Reagents and Intermediates

Negishi, E.; Takahashi, T.

Aldrichim. Acta 1985, 18, 31-48.

(57) 133. Conversion of Methyl Ketones into Terminal Alkynes. (E)-Buten-3-ynyl-2,6,6-trimethyl-1-cyclohexene

Negishi, E.; King, A. O.; Tour, J. M.

Org. Synth. 1986, 64, 44-49.

(127) 134. Carbometallation Reaction of Alkynes with Organoalane-Zirconocene Derivatives as a Route to Stereo- and Regio-

Defined Trisubstituted Alkenes

Negishi, E.; Van Horn, D. E.; Yoshida, T.

J. Am. Chem. Soc. 1985, 107, 6639-6647.

(32) 135. A Mild and Selective Synthesis of Cyclopropene and Cyclopropane Derivatives via Cycliallylation of Alkenyllithiums

Stoll, A. T.; Negishi, E.

Tetrahedron Lett. 1985, 26, 5671-5674.

(27) 136. A Selective Synthesis of 11-Deoxyprostaglandin E2 Methyl Ester and Its 15-Epimer

Luo, F. T.; Negishi, E.

J. Org. Chem. 1985, 50, 4762-4766.

(82) 137. Controlled and Catalytic Acylpalladation. A Novel Route to Cyclopentenone and Cyclohexenone Derivatives

Tour, J. M.; Negishi, E.

J. Am. Chem. Soc. 1985, 107, 8289-8291.

(5) 138. Synthesis of Cyclopentenones and Cyclohexeneones via Cycliacylation of Lithioalkenylcarboxamides

Sawada, H.; Webb, M. B.; Stoll, A. T.; Negishi, E.

Tetrahedron Lett. 1986, 27, 775-778.

(45) 139. On the Origin of the Configurational Instability of 1-Silyl-1-alkenyllithiums and Related Alkenylmetals

Negishi, E.; Takahashi, T.

J. Am. Chem. Soc. 1986, 108, 3402-3408.

(459) 140. Reaction of Zirconocene Dichloride with Alkyllithiums or Alkyl Grignard Reagents as a Convenient Method for

Generating a "Zirconocene" Equivalant and its use in Zirconium-Promoted Cyclization of Alkenes, Alkynes, Dienes,

Enynes, and Diynes

Negishi, E.; Cederbaum, F. E.; Takahashi, T.

Tetrahedron Lett. 1986, 27, 2829-2832.

(50) 141. Complete Reversal of Regiochemistry in Cyclic Acylpalladation. Novel Synthesis of Quinones

Negishi, E.; Tour, J. M.

Tetrahedron Lett. 1986, 27, 4869-4872.

(88) 142. "Bis(triphenylphosphine)palladium": Its Generation, Characterization, and Reactions

Negishi, E.; Takahashi, T.; Akiyoshi, K.

J. Chem. Soc., Chem. Commun. 1986, 1338-1339.

(50) 143. A Selective Method for the Synthesis of Stereodefined Exocyclic Alkenes via Allylmetallation of Propargyl Alcohols

Negishi, E.; Zhang, Y.; Cederbaum, F. E.; Webb, M. B.

J. Org. Chem. 1986, 51, 4080-4082.

145. Potassium (2-Methyl-1-cyclohexenyloxy)triethylborate

Negishi, E.; Chatterjee, S.

Organometal. Synth. 1986, 3, 453-455.

145. (E)-2-Phenyl-1-propenyldimethylalane via Zirconium-Catalyzed Carboalumination of Phenylethyne

Negishi, E.; Van Horn, D. E.

Organometal. Synth. 1986, 3, 467-471.

146. (2E)-1-Trimethylsilyl-3,7-dimethyl-2,6-octadiene (Geranyltrimethylsilane)

Negishi, E.; Luo, F. T.

Organometal. Synth. 1986, 3, 544-546.

(21) 147. Vinylic Organoboranes. 6. A General Stereospecific Synthesis of (E)-Disubstituted Alkenes via Hydroboration-Base-

Induced Migration-Protonolysis of 1-Halo-1-Alkynes

Brown, H. C.; Basavaiah, D.; Kulkarni, S. U.; Lee, H. D.; Negishi, E. and Katz, J.-J.

J. Org. Chem. 1986, 51, 5270-5276.

(96) 148. Zirconium-Promoted Bicyclization of Enynes. Effects of Enyne Structure.

Negishi, E.; Swanson, D. R.; Cederbaum, F. E.; Takahashi, T.

Tetrahedron Lett. 1987, 28, 917-920.

(196) 149. Palladium- or Nickel-Catalyzed Reactions of Alkenylmetals with Unsaturated Organic Halides as a Selective Route to

Arylated Alkenes and Con jugated Dienes: Scope, Limitations, and Mechanism

Negishi, E.; Takahashi, T.; Baba, S.; Van Horn, D. E.; Okukado, N. and Luo, F. T.

J. Am. Chem. Soc. 1987, 109, 2393-2401.

(153) 150. Controlled Carbometallation as a New Tool for Carbon-Carbon Bond Formation and Its Application to Cyclization

Negishi, E.

Acc. Chem. Res. 1987, 20, 65-72.

(118) 151. Zirconacyclopropanes and Zirconacyclopropenes: Their Synthesis, Characterization, and Reactions

Takahashi, T.; Swanson, D. R.; Negishi, E.

Chem. Lett. 1987, 623-626.

(33) 152. Highly Selective Methods for α-Alkenylation and α-Arylation of Ketones via Palladium- or Nickel-Catalyzed Alkenyl-

Alkenyl Coupling

Negishi, E. and Akiyoshi, K.

Chem. Lett. 1987, 1007-1010.

(24) 153. Inhibition of Reductive Elimination of Diorganopalladium Species by Formation of Tetraorganopalladates

Negishi, E.; Akiyoshi, K.; Takahashi, T.

J. Chem. Soc., Chem. Commun. 1987, 477-478.

(39) 154. Palladium-Catalyzed or -Promoted Reductive Carbon-Carbon Coupling. Effects of Phosphines and Carbon Ligands

Negishi, E.; Takahashi, T.; Akiyoshi, K.

J. Organomet. Chem. 1987, 334, 181-194.

(18) 155. Highly Stereoselective Synthesis of Exocyclic Alkenes via Cyclialkylation

Negishi, E.; Zhang, Y.; Bagheri, V.

Tetrahedron Lett. 1987, 28, 5793-5796.

(1) 156. Alkylation and Allylation of Lithium Arylborates. Factors Affecting the Di/Mono Substitution Ratio

Negishi, E.; Merrill, R. E.; Abramovitch, A.; Campbell, D. P.

Bull. Korean Chem. Soc. 1987, 8, 424-425.

(6) 157. Palladium-Catalyzed Synthesis of Conjugated Dienes. (5E,7E)- and (5Z,7E)-5,7- Hexadeadienes

Negishi, E.; Takahashi, T.; Baba, S.

Org. Synth. 1987, 66, 60-66.

(35) 158. 2-Methyl-4'-nitrobiphenyl. Synthesis of Biaryls via Palladium- or Nickel-Catalyzed Cross Coupling

Negishi, E.; Takahashi, T.; King, A. O.

Org. Synth. 1987, 66, 67-74.

(22) 159. A Novel Bicyclization Methodology via Cyclialkylation of ω-Halo-1-metallo-1-alkynes Containing Aluminum and

Zinc

Negishi, E.; Sawada, H.; Tour, J. M.; Wei, Y.

J. Org. Chem. 1988, 53, 913-915.

(207) 160. Organozirconium Compounds in Organic Synthesis

Negishi, E.; Takahashi, T.

Synthesis, 1988, 1, 1-19.

(52) 161. Novel 1,2-Migration Reactions of Organometals Containing Aluminum, Zinc, and Other Main Group Metals with

α-Haloorganolithiums

Negishi, E.; Akiyoshi, K.

J. Am. Chem. Soc. 1988, 110, 646-647.

(43) 162. One-Pot Conversion of Alkynes and Alkenes into One-Carbon Homologated Aldehydes via

Hydrozirconation-Isocyanide Insertion-Hydrolysis

Negishi, E.; Swanson, D. R.; Miller, S. R.

Tetrahedron Lett. 1988, 29, 1631-1634.

(15) 163. Aspects of Cross-Coupling Reactions Catalyzed by Palladium and Nickel Complexes

Negishi, E.; Takahashi, T.; Akiyoshi, K.

"Catalysis of Organic Reactions," Rylander, P. N.; Greenfield, H.; Augustine, R. L., Eds., Mercel Dekker, New York,

1988, p. 381-407.

(57) 164. Novel Silicon-Promoted Cyclialkylation of ω-Halo-1-alkenylmetals Derivatives.

Synthetic Scope and Mechanism

Negishi, E.; Boardman, L. D.; Sawada, H.; Bagheri, V.; Stoll, A. T.; Tour, J.M.; Rand, C. L. J. Am. Chem. Soc. 1988,

110, 5383-5396.

(56) 165. Efficient Synthesis of Carbobicyclic and Carbopolycyclic Compounds via Intramolecular carbopalladation Catalyzed by

Palladium-Phosphine Complex

Negishi, E.; Zhang, Y.; O'Connor, B.

Tetrahedron Lett. 1988, 29, 2915-2918.

(42) 166. Palladium-Catalyzed Cyclization of Alkenyl and Aryl Halides Containing α,β-Unsaturated Carbonyl Groups via

Intramolecular Carbopalladation

O'Connor, B.; Zhang, Y.; Negishi, E.; Luo, F. T.; Cheng, J. W.

Tetrahedron Lett. 1988, 29, 3903-3906.

(41) 167. Palladium-Catalyzed Procedures for [3+2] Annulation via Intramolecular Alkenyl- and Arylpalladation

Zhang, Y.; O'Connor, B.; Negishi, E.

J. Org. Chem. 1988, 53, 5588-5590.

(25) 168. Palladium-Catalyzed Cyclic Acylmetallation of Allylic Electrophiles as a Route to Cyclopentene Derivatives

Negishi, E.; Wu, G.; Tour, J. M.

Tetrahedron Lett. 1988, 29, 6745-6748.

(2) 169. Organometallic Compound

Negishi, E.

1989 Yearbook of Science and Technology, McGraw-Hill, New York, 1988, p. 262-267.

(34) 170. Synthesis of Benzofurans, Tetrahydrobenzofurans, and Related Cyclic Ethers via Cyclic Carbopalladation

Negishi, E.; Nguyen, T.; O'Connor, B.; Evans, J. M.; Silveira, A., Jr.

Heterocycles, 1989, 28, 55-58.

(3) 171. Organic Syntheses Using Zirconium Compounds - Recent Developments (in Japanese)

Negishi, E.; Takahashi, T.

J. Synth. Org. Chem., Japan 1989, 47, 2-10.

(39) 172. Synthesis of Cyclopentanol Derivatives via Palladium-Catalyzed Cyclic Allylpalladation-Dehydropalladation

Negishi, E.; Iyer, S.; Rousset, C. J.

Tetrahedron Lett. 1989, 30, 291-294.

(53) 173. Transition Metal-Promoted Carbon-Carbon Bond Formation Involving α- and γ‑Heterosubstituted Carbanions

Negishi, E.; Akiyoshi, K.; O'Connor, B.; Takagi, K.; Wu, G.

J. Am. Chem. Soc. 1989, 111, 3089-3091.

(374) 174. Novel Bicyclization of Enynes and Diynes Promoted by Zirconocene Derivatives and Conversion of Zirconabicycles into

Bicyclic Enones via Carbonylation

Negishi, E.; Holmes, S. E.; Tour, J. M.; Miller, J. A.; Cederbaum, F. E.; Swanson, D. R.; Takahashi, T.

J. Am. Chem. Soc. 1989, 111, 3336-3346.

(140) 175. Palladium-Catalyzed Cascade Carbometallation of Alkynes and Alkenes as an Efficient Route to Cyclic and Polycyclic

Structures

Zhang, Y.; Negishi, E.

J. Am. Chem. Soc. 1989, 111, 3454-3456.

(74) 176. Zirconocene-Olefin Complexes: An X-Ray Structure and A Novel Preparative Method

Takahashi, T.; Murakami, M.; Kunishige, M.; Saburi, M.; Uchida, Y.; Kozawa, K.; Uchida, T.; Swanson, D. R.; Negishi,

Chem. Lett. 1989, 761-764.

(20) 177. Carbon-Carbon Bond Formation via Opening of Epoxysilanes with Organometals Containing Lithium and Copper

Zhang, Y.; Miller, J. A.; Negishi, E.

J. Org. Chem. 1989, 54, 2043-2044.

(59) 178. Palladium-Catalyzed Cyclization of Benzyl Halides and Related Electrophiles Containing Alkenes and Alkynes as a

Novel Route to Carbocycles

Wu, G.; Lamaty, F.; Negishi, E.

J. Org. Chem. 1989, 54, 2507-2508.

(54) 179. Preparation of a Hafnocene-Ethylene Complex from Bis(η⁵-cyclopentadienyl)- hafnacyclopentane and Its

Characterization

Takahashi, T.; Tamura, M.; Saburi, M.; Uchida, Y.; Negishi, E.

J. Chem. Soc., Chem. Commun. 1989, 852-853.

(0) 180. The Formation of the Carbon-Boron Bond from Organoboranes

Negishi, E.

"Inorganic Reactions and Methods", Vol. 10, Zuckerman, J. J.; Hagen, A. D., Eds., VCH Publishers, Inc., New York,

1989, p. 91-118.

(72) 181. Metal-Organic Approach to the Stereoselective Synthesis of Exocyclic Alkenes

Negishi, E.

Advan. Metal-Org. Chem. 1989, 1, 177-207

(116) 182. Regio- and Diastereoselective Alkyl-Alkene and Alkene-Alkene Coupling Promoted by Zirconocene and Hafnocene

Swanson, D. R.; Rousset, C. J.; E. Negishi.; Takahashi, T.; Seki, T,; Saburi, M.; Uchida, Y.

J. Org. Chem. 1989, 54, 3521-3523.

(27) 183. Carbonylative Cyclization via Intramolecular Trapping of Acylmetal Derivatives by Carbon Nucleophiles Catalyzed by

Late Transition Metals

Negishi, E.; Zhang, Y., Shimoyama, I.; Wu. G.

J. Am. Chem. Soc. 1989, 111, 8018-8020.

(139) 184. Zirconocene-Promoted Stereoselective Bicyclization of 1,6- and 1,7-Dienes to Produce trans-Zirconabicyclo[3.3.0]

octanes and cis-Zirconabicyclo[4.3.0.]onanes

Rousset, C. J.; Swanson, D. R.; Lamaty, F.; Negishi, E.

Tetrahedron Lett. 1989, 30, 5105-5108.

(31) 185. Stereoselective Synthesis of Exocyclic Alkenes via Zirconium-Promoted Alkyl-Diene Coupling

Negishi, E.; Miller, S. R.

J. Org. Chem. 1989, 54, 6014-6016.

(55) 186. Cyclization, Coupling, and Rearrangement Reactions of Organozirconium and Related Compounds

Ei-ichi Negishi

Chimica Scripta 1989, 29, 457-468.

(46) 187. Selective Skeletal Rearrangement by Carbon-Carbon Bond Activation

Takahashi, T.; Fujimori, T.; Seki, T.; Saburi, M.; Uchida, Y.; Rousset, C. J.; Negishi, E.

J. Chem. Soc., Chem. Commun. 1990, 182-183.

(37) 188. Stereoselective Cyclic Carbolithiation of Alkyne Derivatives. A Stereoselective Synthesis of Exocyclic Alkenes

Wu, G.; Cederbaum, F. E.; Negishi, E.

Tetrahedron Lett. 1990, 31, 493-496.

(33) 189. Synthesis of Enol Esters via Palladium-Catalyzed Carbonylation of Aryl and Alkenyl Halides

Shimoyama, I.; Zhang, Y.; Wu, G.; Negishi, E.

Tetrahedron Lett. 1990, 31, 2841-2844.

(49) 190. Effects of Organometals on the Palladium-Catalyzed Tandem Carbopalladation-Cross Coupling for Preparing

Stereodefined Exocyclic Alkenes

Negishi, E.; Noda, Y.; Lamaty, F.; Vawter, E. J.

Tetrahedron Lett. 1990, 31, 4393-4396.

(41) 191. Nondissociative Mechanism for Decomposition of Dialkylzirconocenes to produce Alkene-Zirconocene-Phosphine

Complexes

Negishi, E.; Swanson, D. R.; Takahashi, T.

J. Chem. Soc., Chem. Commun. 1990, 18, 1254-1255.

(130) 192. Clean and Convenient Procedure for Converting Primary Alkyl Iodides and α,ω‑Diiodoalkanes into the Corresponding

Alkyllithium Derivatives by Treatment with t-Butyllithium

Negishi, E.; Swanson, D. R.; Rousset, C. J.

J. Org. Chem. 1990, 55, 5406-5409.

(90) 193. Palladium-Catalyzed One-Step Tri- and Tetracyclization of Acyclic Polyenynes. A Novel Route to a Steroidal

Skeleton

Zhang, Y.; Wu, G.; Agnel, G.; Negishi, E.

J. Am. Chem. Soc. 1990, 112, 8590-8592.

(37) 194. Reaction of Dimethylzirconocene with Alkylmagnesium Halides as a Potentially General Method for Preparing

Zirconocene-Alkene Complexes

Takahashi, T.; Nitto, Y.; Seki, T.; Saburi, M.; Negishi, E.

Chem. Lett. 1990, 2259-2262.

(43) 195. Novel Zirconium-Promoted Carbon-Carbon Bond Formation via a 1,2-Migration Reaction of Alkynylzirconium

Derivatives

Takagi, K.; Rousset, C. J.; Negishi, E.

J. Am. Chem. Soc. 1991, 113, 1440-1442.

(69) 196. General and Convenient Procedure for the Preparation of Zirconocene Complexes of Alkenes and Conjugated Dienes

Swanson, D. R.; Negishi, E.

Organometallics 1991, 10, 825-826.

(24) 197. A Convenient Procedure for Hydrozirconation of Alkynes with i-BuZrCp₂Cl Generated in Situ by Treatment of

Cp₂ZrCl₂ with t-BuMgCl

Swanson, D. R.; Nguyen, T.; Noda, Y.; Negishi, E.

J. Org. Chem. 1991, 56, 2590-2591.

(129) 198. Remarkably "Pair" -Selective and Regioselective Carbon-Carbon Bond Forming Reaction of Zirconacylclopentane

Derivatives with Grignard

Takahashi, T.; Seki, T.; Nitto, Y.; Saburi, M.; Rousset, C. J.; Negishi, E.

J. Am. Chem. Soc. 1991, 113, 6266-6268.

(25) 199. Highly Stereoselective Synthesis of Conjugated E,E- and E,Z-Dienes, E-Enynes, and E-1,2,3-Butatrienes via

Alkenylborane Derivatives

Negishi, E.; Yoshida, T.; Abramovitch, A.; Lew, G.; Williams, R. M.

Tetrahedron 1991, 47, 343-356.

(204) 200. Zirconium-promoted Bicyclization of Enynes

Negishi, E.

"Comprehensive Organic Synthesis", Vol. 5, Paquette, L. A., Ed., Pergamon, 1991, 1163-1184.

(64) 201. Strictly Regio-Controlled Method for α-Alkenylation of Cyclic Ketones via Palladium-Catalyzed Cross Coupling

Negishi, E.; Owczarczyk, Z.; Swanson, D. R.

Tetrahedron Lett. 1991, 32, 4453-4456.

(51) 202. Highly Stereo- and Regiocontrolled Cyclopentannulation via Allylphosphonate Conjugate Addition and Hydroboration-

Oxidation-Elimination. Synthesis of Pentalenic Acid with Virtually Complete Stereo- and Regiocontrol

Agnel, G.; Negishi, E.

J. Am. Chem. Soc. 1991, 113, 7424-7426.

(104) 203. Zirconium-Catalyzed, Highly Regioselective Hydrosilation Reaction of Alkenes and X-Ray Structures of Silyl(hydrido)

zirconocene Derivatives

Takahashi, T.; Hasegawa, M.; Suzuki, N.; Saburi, M.; Rousset, C. J.; Fanwick, P. E.; Negishi, E.

J. Am. Chem. Soc. 1991, 113, 8564-8566.

(62) 204. Catalytic Hydrogenation of Alkenes Using Zirconocene-Alkene Complexes

Takahashi, T.; Suzuki, N.; Kageyama, M.; Nitto, Y.; Saburi, M.; Negishi, E.

Chem. Lett. 1991, 1579-1582.

(49) 205. Highly Selective Synthesis of Vitamin A and its Derivatives. Critical Comparison of Some Known Palladium-

Catalyzed Alkenyl-Alkenyl Coupling Reactions

Negishi, E.; Owczarczyk, Z.

Tetrahedron Lett. 1991, 32, 6683-6686.

(28) 206. Palladium-Catalyzed Carbonylative Cyclization of o-Allylbenzyl Halides to Produce Benzo-Annulated Enol Lactones

and/or Bicyclo[3.3.0]hept-3-en-6-ones. An Efficient Route to U-68,215

Wu, G.; Shimoyama, I.; Negishi, E.

J. Org. Chem. 1991, 56, 6506-6507.

(18) 207. Carbon-Carbon Bond Formation by the Reaction of Organolithiums with α-Lithiated Cyclic Enol Ethers.

Stereoselective Synthesis of β- and γ-Hydroxy Di- and Tri-Substituted Alkenes

Nguyen, T.; Negishi, E.

Tetrahedron Lett. 1991, 32, 5903-5906.

(27) 208. Novel Head-to-Tail Alkyl-Alkene or Alkene-Alkene Coupling via Zirconium-Catalyzed Reaction of Alkylmagnesium

Derivatives with Monosubstituted Alkenes

Rousset, C. J.; Negishi, E.; Suzuki, N.; Takahashi, T.

Tetrahedron Lett. 1992, 33, 1965-1968.

(107) 209. Zipper-Mode Cascade Carbometallation for Construction of Polycyclic Structures

Negishi, E.

Pure Appl. Chem. 1992, 74, 323-334.

(6) 210. Zirconocene-Alkene Complexes: Their Formation, Structure, and Reactions

Negishi, E.; Takahashi, T.

Rev. Heteroatom Chem. 1992, 6, 177-201.

(53) 211. Diastereoselective Zirconocene-Promoted Bicyclization-Carbonylation of Allylically Methyl-Substituted Enynes.

Synthesis of (+)-Iridomyrmecin

Agnel, G.; Owczarczyk, Z.; Negishi, E.

Tetrahedron Lett. 1992, 33, 1543-1546.

(4) 212. Cyclization Reactions of ω-Tosyloxy-1-alkynyl- and ω-Tosyloxy-1-alkenylborates and Their ω-Halo Analogues

Negishi, E.; Nguyen, T.; Boardman, L. D.; Sawada, H.; Morrison, J. A.

Heteroatom Chem., 1992, 3, 293-302.

(62) 213. Cyclic Cascade Carbopalladation Reactions as a Route to Benzene and Fulvene Derivatives

Negishi, E.; Harring, L. S.; Owczarczyk, Z.; Mohamud, M. M.; Ay, M.

Tetrahedron Lett., 1992, 33, 3253-3256.

(42) 214. Factors Affecting the Unusual Reactivity Order in the β-Hydrogen Abstraction of Dialkylzirconocenes

Negishi, E.; Nguyen, T.; Maye, J. P.; Choueiri, D.; Suzuki, N.; Takahashi, T.

Chem. Lett. 1992, 2367-2370.

(65) 215. Apparent Endo-Mode Cyclic Carbopalladation with Inversion of Alkene Configuration via Exo-Mode Cyclization-

Cyclopropanation-Rearrangement

Owczarczyk, Z.; Lamaty, F.; Vawter, E. J.; Negishi, E.

J. Am. Chem. Soc. 1992, 114, 10091-10092.

(137) 216. Facile Cleavage of the C-C¢ Bond of Zirconacyclopentenes. Convenient Method for Selectively Coupling Alkynes with

Alkynes, Nitriles, and Aldehydes.

Takahashi, T.; Kageyama, M.; Denisov, V.; Hara, R.; Negishi, E.

Tetrahedron Lett. 1993, 34, 687-690.

(42) 217. Highly Stereoselective and General Synthesis of (Z)-3-Methyl-2-alken-1-ols via Palladium-Catalyzed Cross Coupling

of (Z)-3-Iodo-2-buten-1-ol with Organozincs and Other Organometals.

Negishi, E.; Ay, M.; Gulevich, Y. V.; Noda, Y.

Tetrahedron Lett. 1993, 34, 1437-1440.

(28) 218. Selective Synthesis of Benzene Derivatives via Palladium-Catalyzed Cascade Carbometallation of Alkynes

Negishi, E.; Ay, M.; Sugihara, T.

Tetrahedron, 1993, 49, 5471-5482.

(28) 219. Conversion of Non-conjugated Dienes into Conjugated Diene-Zirconocenes via Multipositional Regioisomerization

Maye, J. P. and Negishi, E.

Tetrahedron Lett. 1993, 34, 3359-3362.

(27) 220. Zirconium Catalyzed C-C Bond Formation Reaction of Conjugated Diynes with EtMgBr

Takahashi, T; Aoyagi, K.; Denisov, V.; Suzuki, N.; Choueiry, D.; Negishi, E.

Tetrahedron Lett., 1993, 34, 8301-8304.

(6) 221. Convenient Synthesis of Diene-Zirconocenes and Regioselective Partial Reduction of the More Highly Substituted

Double Bonds of Conjugated Dienes via Complexation with Zirconocenes and Protonolysis

Maye, J. P.; Negishi, E.

J. Chem. Soc. Chem. Commun., 1993, 1830-1831.

(22) 222. Palladium-Catalyzed Carbonylative Cyclization via Trapping of Acylpalladium Derivatives with Internal Enolates. Its

Scope and Factors Affecting the C-to-O Ratio

Negishi, E.; Copéret, C.; Sugihara, T.; Shimoyama, I.; Zhang, Y.; Wu, G.; Tour, J. M.

Tetrahedron, 1994, 50, 425-436.

(62) 223. Reaction of 3-Zircona-1-cyclopentenes and Zirconacyclopentanes with Aldehydes. A Selective and Convenient

Synthesis of 4-Penten-1-ols, (Z)-5-Iodo-4-penten-1-ols, and Related Alkanols

Copéret, C., Negishi, E.; Xi, Z.; Takahashi, T.

Tetrahedron Lett., 1994, 35, 695-698.

(23) 224. Isolation and Characterization of the Ethylene-Bridged Zirconocene Complex (Cp₂ZrMe)₂(CH₂CH₂)

Takahashi, T.; Kasai, K.; Suzuki, N.; Nakajima, K.; Negishi, E.

Organometallics, 1994, 13, 3413-3414.

(319) 225. Patterns of Stoichiometric and Catalytic Reactions of Organozirconium and Related Complexes of Synthetic Interest

Negishi, E.; Takahashi, T.

Acc. Chem. Res., 1994, 27, 124-130.

(47) 226. Deferred Carbonylative Esterification in the Pd-Catalyzed Cyclic Carbometallation-Carbonylation Cascade

Sugihara, T.; Copéret, C.; Owczarczyk, Z.; Harring, L. S.; Negishi, E.

J. Am. Chem. Soc., 1994, 116, 7923-7924.

(46) 227. Facile Formation of Seven- and Eight-Membered Cycloalkenes via Catalytic and Cyclic Carbopalladation of Allenes

Ma, S.; Negishi, E.

J. Org. Chem., 1994, 59, 4730-4732.

(48) 228. Titanium-Catalyzed Cascade Carboalumination of Dienes and Trienes

Negishi, E.; Jensen, M. J.; Kondakov, D. Y.; Wang, S.

J. Am. Chem. Soc., 1994, 116, 8404-8405.

(44) 229. Nonconcerted Paths for Reactions of Alkene-Zirconocene Complexes

Negishi, E.; Choueiry, D.; Nguyen, T. B.; Swanson, D. R.; Suzuki, N.; Takahashi, T.

J. Am. Chem. Soc., 1994, 116, 9751-9752.

(0) 230. Novel Structures and Reaction Patterns in Organozirconium and Related Chemistry

Negishi, E.

Seminars in Organic Synthesis: XIX Summer School "A. Corbella", Società Chimica. Italiana, 1994, p. 7-24.

(15) 231. Termination of Carbopalladation of Alkynes via Carbonylative Amidation Producing Lactams

Copéret, C.; Sugihara, T.; Negishi, E.

Tetrahedron Lett., 1995, 36, 1771-1774.

(59) 232. Stoichiometric Reactions of Nonconjugated Dienes with Zirconocene Derivatives. Further Delineation of the Scope of

Bicyclization and Observation of a Novel Multipositional Alkene Regioisomerization

Negishi, E.; Maye, J. P.; Choueiry, D.

Tetrahedron, 1995, 51, 4447-4462.

(58) 233. Acylpalladation of Internal Alkynes and Palladium-Catalyzed Carbonylation of (Z)-β-Iodoenones Related Derivatives

Producing γ-Lactones and γ-Lactams

Copéret, C.; Sugihara, T.; Wu, G.; Shimoyama, I.; Negishi, E.

J. Am. Chem. Soc., 1995, 117, 3422-3431.

(95) 234. Palladium-Catalyzed Cyclization of ω-Haloallenes. A New General Route to Common, Medium, and Large Ring

Compounds via Cyclic Carbopalladation

Ma, S.; Negishi, E.

J. Am. Chem. Soc., 1995, 117, 6345-6357

(74) 235. Zirconium-Catalyzed Enantioselective Methylalumination of Monosubstituted Alkenes

Kondakov, D.; Negishi, E.

J. Am. Chem. Soc., 1995, 117, 10771-10772.

(0) 236. 1-Chloro-2-iodoethylene.

Negishi, E.; Copéret, C.

"Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A., ed. Wiley, New York, 1995, Vol. 2, 1142-1143.

(1) 237. n-Butyllithium-Dichlorobis(η5-cyclopentadienyl)zirconium. Di(n-butyl)zirconocene.

Negishi, E.

"Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A., ed. Wiley, New York, 1995, Vol. 3, 1593-1596.

(3) 238. Trimethylaluminum-Dichlorobis(η5-cyclopentadienyl)titanium.

Negishi, E.; Choueiry, D.

"Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A., ed. Wiley, New York, 1995, Vol. 7, 5190-5192.

(1) 239. Trimethylaluminum-Dichlorobis(η5-cyclopentadienyl)zirconium.

Negishi, E.; Choueiry, D.

"Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A., ed. Wiley, New York, 1995, Vol. 7, 5192-5195.

(4) 240. The Synthesis of Vinyl- and Arylmetals

Negishi, E.; Choueiry, D.

"Organic Functional Group Transformations," Katritzky, A. R.; Meth-Cohn, O.; Rees, C. W., eds., Pergamon Press,

Oxford, 1995, Vol. 2, 951-995.

(353) 241. Cyclic Carbopalladation. A Versatile Synthetic Methodology for the Construction of Cyclic Organic Compounds

Negishi, E.; Copéret, C.; Liou, S. Y.; Liu, F.; Ma, S.

Chem. Rev., 1996, 96, 365-393.

(77) 242. Zirconium-Catalyzed Enantioselective Alkylalumination of Monosubstituted Alkenes Proceeding via Noncyclic

Mechanism

Kondakov, D. Y.; Negishi, E.

J. Am. Chem. Soc.,1996, 118, 1577-1578.

(57) 243. Palladium-Catalyzed Carbonylative Cyclization of 1-Iodo-2-alkenylbenzenes

Negishi, E.; Copéret, C.; Ma, S.; Mita, T.; Sugihara, T.; Tour, J. M.

J. Am. Chem. Soc., 1996, 118, 5904-5918.

(39) 244. Palladium-Catalyzed Cyclization of 1-Iodo-Substituted 1,4-, 1,5-, and 1,6-Dienes as Well as of 5-Iodo-1,5-dienes in the

Presence of Carbon Monoxide

Negishi, E.; Ma, S.; Amanfu, J.; Copéret, C.; Miller, J. A.; Sugihara, T.; Tour, J. M.

J. Am. Chem. Soc., 1996, 118, 5919-5931.

(13) 245. Titanium-Catalyzed Cascade Carboalumination of 2-Alkyl-Substituted Dienes and Trienes

Kondakov, D. Y.; Wang, S.; Negishi, E.

Tetrahedron Lett., 1996, 37, 3803-3806.

(11) 246. Facile and Reversible Formation of Monocyclopentadienylzirconium Derivatives by the Reaction of Cp2ZrCl2 with

Alkyllithiums and Their Reactions with Electrophiles and Olefins

Kondakov, D. Y.; Negishi, E.

J. Chem. Soc., Chem. Commun., 1996, 963-964.

(14) 247. Palladium-Catalyzed Cascading Carbonylative Cyclization of Iodo-Dienes and -Trienes

Copéret, C.; Ma, S.; Negishi, E.

Angew. Chem., Int. Ed. Engl., 1996, 2125-2126.

(18) 248. A Selective Procedure of α-Alkenylation of Enones Involving Pd-Catalyzed Alkenyl-Alkenyl Coupling and Its

Application of a Convergent and Efficient Synthesis of Nakienone B

Pour, M.; Negishi, E.

Tetrahedron Lett., 1996, 37, 4679-4682.

(14) 249. Cyclic Carbopalladation of Alkynes Terminated by Carbonylative Amidation

Copéret, C.; Ma, S.; Sugihara, T.; Negishi, E.

Tetrahedron, 1996, 52, 11529-11544.

(3) 250. Reaction of Alkynes with Organometallic Reagents

Negishi, E.; Choueiry, D.

"Preparation of Alkynes: A Practical Approach," Williams, J. M. J., Ed., Oxford University Press, Oxford, 137-156.

(53) 251. Multiple Mechanistic Pathways for Zirconium-Catalyzed Carboalumination of Alkynes

Negishi, E.; Kondakov, D. Y.; Choueiry, D.; Kasai, K.; Takahashi, T.

J. Am. Chem. Soc., 1996, 118, 9577-9588.

(47) 252. An Odyssey from Stoichiometric Carbotitanation of Alkynes to Zirconium-Catalyzed Enantioselective

Carboalumination of Alkenes

Negishi, E.; Kondakov, D. Y.

Chem. Soc. Rev., 1996, 26, 417-426.

(17) 253. Convenient and General Synthesis of 1-Monoorganyl- and 1,2,-Diorganylcyclobutenes via Cyclialkylation

Negishi, E.; Liu, F.; Choueiry, D.; Mohamud, M. M.; Silveira, A. Jr.; Reeves, M.

J. Org. Chem., 1996, 61, 8325-8328.

(27) 254. Efficient and Diastereoselective Synthesis of (+)-Goniobutenolide A via Palladium-Catalyzed Ene-Yne Cross

Coupling-Lactonization Cascade

Kotora, M.; Negishi, E.

Tetrahedron Lett., 1996, 37, 9041-9042.

(57) 255. Highly Efficient and Selective Procedures for the Synthesis of γ-Alkylidenebutenolides and Its Application to the

Synthesis of Rubrolides A, C, D, and E

Kotora, M.; Negishi, E.

Synthesis, 1997, 121-128.

(15) 256. An Efficient and Selective Synthesis of Nakienone A Involving a Novel Protocol of α-Alkenylation of Ketones via

Palladium-Catalyzed Alkenyl-Alkenyl Coupling

Pour, M.; Negishi, E.

Tetrahedron Lett., 1997, 38, 525-528

(9) 257. On the Regiochemistry of Cyclialkylation of Regiodefined 4-Halo-1-alkenylmetals Producing Cyclobutenes

Liu, F.; Negishi, E.

Tetrahedron Lett., 1997, 38, 1149-1152.

(27) 258. Anti-Carbometallation of Homopropargyl Alcohols and Their Higher Homologues via Non-Chelation-Controlled Syn-

Carbometallation and Chelation-Controlled Isomerization

Ma, S.; Negishi, E.

J. Org. Chem., 1997, 62, 784-785.

(9) 259. Carbometallation Reactions of Diphenylacetylene and Other Alkynes with Methylalanes and Titanocene Derivatives

Negishi, E.; Kondakov, D. Y.; Van Horn, D. E.

Organometallics, 1997, 16, 951-957.

(102) 260. Regio- and Stereoselective Synthesis of γ-Alkylidenebutenolides and Related Compounds

Negishi, E.; Kotora, M.

Tetrahedron, 1997, 53, 6707-6738.

(26) 261. Synthesis of Hydrazulenes via Zr-Promoted Bicyclization of Enynes and Transition Metal-Catalyzed or Radical Cyclization

of Alkenyl Iodides. Efficient Synthesis of (±)-7-epi-β-Bulnesene

Negishi, E.; Sugihara, T.; Ma, S.; Noda, Y.

J. Org. Chem., 1997, 62, 1922-1923.

(148) 262. Pd- or Ni-Catalyzed Cross Coupling with Organometals Containing Zn, Mg, Al, and Zr

Negishi, E.; Liu, F.

Chapter 1 in Cross Coupling Reactions, Stang, P. J.; Diederich, F., Eds., VCH, Weinheim, 1998, p. 1-47.

(8) 263. Anti-Hydroalumination of Homo- and Bishomopropargyl Alcohols

Ma, S.; Liu, F.; Negishi, E.

Tetrahedron Lett., 1997, 38, 3829-3832.

(39) 264. Convenient Preparative Method of α,β-Disubstituted Cyclopentenone by Zirconocene- Promoted Intermolecular

Coupling of an Alkyne, EtMgBr (or Ethylene) and CO

Takahashi, T.; Xi, Z.; Nishihara, Y.; Huo, S.; Kasai, K.; Aoyagi, K.; Denisov, V.; Negishi, E.

Tetrahedron, 1997, 53, 9123-9134.

(18) 265. Direct Synthesis of Heteroarylethynes via Palladium-Catalyzed Coupling of Heteroaryl Halides with Ethynylzinc Halides.

Its Application to an Efficient Synthesis of a Thiophenelactone from Chamaemelum Nobile L.

Negishi, E.; Xu, C.; Tan, Z.; Kotora, M.

Heterocycles, 1997, 46, 209-214.

(37) 266. Efficient and Stereoselective Synthesis of Freelingyne via Pd-Catalyzed Cross Coupling and Lactonization

Liu, F.; Negishi, E.

J. Org. Chem., 1997, 62, 8591-8594.

(40) 267. Convenient and Direct Synthesis of Terminal Alkynes via Pd-Catalyzed Cross Coupling. Critical Comparison of

Countercations

Kotora, M.; Xu, C.; Negishi, E.

J. Org. Chem., 1997, 62, 8957-8960.

(3) 268. Enantiomerically Pure Zirconium and Hafnium Complexes Containing a Chiral Cyclopentadiene Derivative Prepared

from (-)-β-Pinene

Rousset, C. J.; Iyer, S.; Negishi, E.

Tetrahedron: Asymmetry, 1997, 8, 3921-3926.

(7) 269. Catalytic Generation and Trapping of Acylmetals Containing Ni and Cu with Enolates

Negishi, E.; Makabe, H.; Shimoyama, I.; Wu, G.; Zhang, Y.

Tetrahedron, 1998, 54, 1095-1106.

(100) 270. Alkene and Alkyne Complexes at Zirconocene. Their Preparation, Structure and Novel Transformations

Negishi, E.; Takahashi, T.

Bull. Chem. Soc. Jpn, 1998, 71, 755-769.

(16) 271. Carbozincation of Enynes Catalyzed by Titanium(IV) Alkoxides and Alkylmagnesium Derivatives

Montchamp, J.-L.; Negishi, E.

J. Am. Chem. Soc., 1998, 120, 5345-5346.

(14) 272. Zirconium-Catalyzed and Zirconium-Promoted Cyclization Reactions of Nonconjugated Dienes with Alkylmagnesium

Halides to Give Cycloalkylmethylmagnesium Derivatives

Negishi, E.; Rousset, C. J.; Choueiry, D.; Maye, J. P.; Suzuki, N.; Takahashi, T.

Inorg. Chim. Acta, 1998, 280/1-2, 8-20.

(24) 273. Zirconium-Catalyzed Carboalumination of Alkynes and Enynes as a Route to Aluminacycles and Their Conversion to

Cyclic Organic Compounds

Negishi, E.; Montchamp, J.-L.; Anastasia, L.; Elizarov, A.; Choueiry, D.

Tetrahedron Lett., 1998, 39, 2503-2506.

(16) 274. Strictly Regio- and Stereo-Controlled α-Alkenylation of Bicyclic Enones and Their Derivatives via Palladium-

Catalyzed Cross Coupling and Its Application to a Formal Synthesis of (±)-Carbacyclin

Negishi, E.; Pour, M.; Cederbaum, F. E.; Kotora, M.

Tetrahedron, 1998, 54, 7057-7074.

(21) 275. Zirconocenes

Negishi, E.; Montchamp, J. L.

Chapter 5 in Metallocenes, Togni, A.; Halterman, R. L., Eds., VCH, Weinheim, 1998, 241-319.

(49) 276. Selective Intermolecular Coupling of Alkynes with Nitriles and Ketones via β, β¢ Carbon-Carbon Bond Cleavage of

Zirconacyclopentenes

Takahashi, T.; Xi, C.; Xi, Z.; Kageyama, M.; Fischer, R.; Nakajima, K.; Negishi, E.

J. Org. Chem., 1998, 63, 6802-6806.

(25) 277. Palladium- and Nickel-Catalyzed Reactions of Organozinc Compounds

Negishi, E.

Chapter 11 in Organozinc Reagents: A Practical Approach, Knochel, P. and Jones, P., Ed., Oxford University Press, Oxford, 1999, 213-243.

(58) 278. A Highly Efficient and Selective Synthesis of Lissoclinolide Featuring Hydrogen Transfer Hydrozirconation, trans-

Selective Pd-Catalyzed Cross Coupling of Alkenylzirconiums with 1,1-Dibromoalkenes and Ag-Catalyzed Lactonization Providing (Z)-γ-Alkylidenebutenolides

Xu, C.; Negishi, E.

Tetrahedron Lett., 1999, 40, 431-434.

(3) 279. Intermolecular Trapping of Acylpalladium and Related Acylmetal Derivatives with Active C‑H Compounds

Negishi, E.; Liou, S.-Y.; Xu, C.; Shimoyama, I.; Makabe, H.

J. Mol. Cat., 1999, 143, 279-286.

(27) 280. Principle of Activation of Electrophiles by Electrophiles through Dimeric Association - Two is Better than One

Negishi, E.

Chem. Eur. J., 1999, 5, 411-420.

(14) 281. Palladium-Catalyzed Highly Diastereoselective Cyclic Carbopalladation-Carbonylative Esterification Tandem Reaction

of Iododienes and Iodoarylalkenes

Coperét, C.; Negishi, E.

Org. Lett., 1999, 1, 165-167.

(6) 282. Hydrogen Transfer Hydrozirconation of Alkenes with i-BuZrCp₂Cl Catalyzed by Lewis-Acidic Metal Compounds

Containing Al, Zn, Si, Ag, Ni, and Pd

Makabe, H.; Negishi, E.

Eur. J. Org. Chem. 1999, 969-971.

(12) 283. Synthesis of α-Iodo-α,β-unsaturated Ketones by the Reaction of α-Silyl-α,β-unsaturated Ketones with ICl or ICl-AlCl₃

Alimardanov, A.; Negishi, E.

Tetrahedron Lett. 1999, 40, 3839-3842.

(13) 284. Highly Chemo-, Regio-, and Stereoselective Carbon-Carbon Bond Formation via Migratory Insertion Reaction of

Zirconacyclopentene Derivatives and Alkynylmetals Containing Li and Mg. Novel Synthesis of 1,5-Dienes and 1,5-Enynes

Dumond, Y.; Negishi, E.

J. Am. Chem. Soc.,1999, 121, 11223-11224.

(21) 285. Novel and Selective α-Substitution of Ketones and Other Carbonyl Compounds Based on Pd-Catalyzed Cross

Coupling of α,β-Unsaturated Carbonyl Derivatives Containing α-Halogen or α-Metal Groups

Negishi, E.

J. Organomet. Chem., 1999, 576, 179-194.

(0) 286. Novel and Selective α-Substitution of Ketones and Other Carbonyl Compounds Based on Pd-Catalyzed Cross

Coupling of α,β-Unsaturated Carbonyl Derivatives Containing α-Halogen or α-Metal Groups

Negishi, E.

In Perspective in Organopalladium Chemistry for the 21 Century,” Tsuji, J., Ed., Elsevier, 1999, 179-194.

(34) 287. An Efficient and Stereoselective Synthesis of Xerulin via Pd-Catalyzed Cross Coupling and Lactonization Featuring

(E)-Iodobromoethylene as a Novel Two-Carbon Synthon

Negishi, E.; Alimardanov, A.; Xu, C.

Org. Lett., 2000, 2, 65-67.

(2) 288. A General Method for the Synthesis of E and/or Z Oligoisoprenoids Based on Pd-Catalyzed Homoallyl-Alkenyl and

Homopropargyl-Alkenyl Cross Coupling and Zr-Catalyzed Carboalumination

Negishi, E.; Liou, S. Y.; Xu, C.; Huo, S.

Polyhedron, 2000, 19, 591-592.

(1) 289. Development of a Method for the Synthesis of α-Substituted α,β-Unsaturated Lactones Based on Stille-Type Pd-

Catalyzed Carbonylation of (Z)-ω-Iodoalkenols. An Efficient and Selective Synthesis of (+)-Hamabiwalactone B

Liao, B.: Negishi, E.

Heterocycles, 2000, 52, 1241-1249.

(7) 290. Asymmetric Carbometallations

Negishi, E.

Chapter 4 in Catalytic Asymmetric Synthesis II, Ojima, I., Ed., J. Wiley-VCH, New York, 2000, 165-189.

(15) 291. Ethylzincation of Monosubstituted Alkenes Catalyzed by EtMgBr-Cl₂ZrCp₂ and Palladium-Catalyzed Cross Coupling of

the Resultant Diisoalkylzinc Derivatives

Gagneur, S.; Montchamp, J. L.; Negishi, E.

Organometallics, 2000, 19, 2417-2419.

(17) 292. A Strictly “Pair”-Selective Synthesis of Conjugated Diynes via Pd-Catalyzed Cross Coupling of 1,3-Diynylzincs: A Superior

Alternative to the Cadiot-Chodkiewicz Reaction

Negishi, E.; Hata, M.; Xu, C.

Org. Lett., 2000, 2, 3687-3689.

(15) 293. Strictly Regiocontrolled α-Monosubstitution of Cyclic Carbonyl Compounds with Alkynyl and Alkyl Groups via Pd-

Catalyzed Coupling of Cyclic α-Iodoenones with Organozincs

Negishi, E.; Tan, Z.; Liou, S. Y.; Liao, B.

Tetrahedron, 2000, 56, 10197-10207.

(3) 294. A Novel Hydrogen Transfer Hydroalumination of Alkenes with Triisobutylaluminum Catalyzed by Pd and Other Late

Transition Metal Complexes

Gagneur, S.; Makabe, H.; Negishi, E.

Tetrahedron Lett., 2001, 42, 785-787.

(8) 295. Some Newer Aspects of Organozirconium Chemistry of Relevance to Organic Synthesis. Zr-Catalyzed Enantioselective

Carbometallation

Negishi, E.

Pure Appl. Chem., 2001, 73, 239-242.

(33) 296. A Novel, Selective, and Efficient Route to Carotenoids and Related Natural Products via Zr-Catalyzed

Carboalumination and Pd- and Zn-Catalyzed Cross Coupling

Zeng, F.; Negishi, E.

Org. Lett., 2001, 3, 719-722.

(6) 297. Stereoselective Synthesis of Exocyclic Alkenes via Cu-Catalyzed Allylmagnesiation, Pd-Catalyzed Alkylation, and Ru-

Catalyzed Ring Closing Olefin Metathesis: Highly Stereoselective Synthesis of (Z)- and (E)-γ-Bisabolenes

Dumond, Y.; Anastasia, L.; Negishi, E.

Eur. J. Org. Chem. 2001, 3039-3043.

(28) 298. Highly Satisfactory Procedures for the Pd-Catalyzed Cross Coupling of Aryl Electrophiles with in Situ Generated

Alkynylzinc Derivatives

Anastasia, L.; Negishi, E.

Org. Lett., 2001, 3, 3111-3113.

(26) 299. A Convenient and Asymmetric Protocol for the Synthesis of Natural Products Containing Chiral Alkyl Chains via Zr-

Catalyzed Asymmetric Carboalumination of Alkenes. Syntheses of Phytol and Vitamins E and K

Huo, S.; Negishi, E.

Org. Lett., 2001, 3, 3253-3256.

(4) 300. Organozirconium Chemistry in Organic Synthesis

Negishi, E.

Chapter 8 in Organometallics in Synthesis: A Manual, 2nd Ed., Schlosser, M., Ed., Wiley, New York, 2002, 926-1002.

(1) 301. Zirconium-Catalyzed Enantioselective Carboalumination of “Unactivated” Alkenes as a New Synthetic Tool for

Asymmetric Carbon-Carbon Bond Formation

Negishi, E.; Huo, S.

Pure Appl. Chem. 2002, 74, 151-157.

(31) 302. A Genealogy of Pd-Catalyzed Cross Coupling

Negishi, E.

J. Organomet. Chem. 2002, 653, 34-40.

(20) 303. Synthesis and Reactivity of Zirconocene Derivatives

Negishi, E.; Huo, S.

Chapter 1 in Titanium and Zirconium in Organic Synthesis, Marek, I., Ed., Wiley-VCH, Weinheim, 2002, 1-49.

(0) 304. (-)-Dichlorobis[(1,2,3,3a,7a-η)-1-[(1S,2S,5R)-5-methyl-2-(1-methylethyl)]cyclohexyl-1H- inden-1-y]zirconium and Its

(+)-(1R,2R,5S)-Isomer

Negishi, E.; Huo, S.

“Encyclopedia of Reagents for Organic Synthesis”, Paquette, L. A., Ed., Wiley, New York, 2002.

(18) 305. A New Protocol for the Enantioselective Synthesis of Methyl-Substituted Chiral Alkanols and Their Derivatives via

Hydroalumination–Zirconium Catalyzed Alkylalumination Tandem Process

Huo, S.; Shi, J.; Negishi, E.

Angew. Chem. Int. Ed. 2002, 41, 2141-2143.

(21) 306. A Novel, Highly Selective, and General Methodology for the Synthesis of 1,5-Diene-Containing Oligoisoprenoids of All

Possible Geometrical Combinations Exemplified by an Iterative and Convergent Synthesis of Coenzyme Q10

Negishi, E.; Liou, S. Y.; Xu, C.; Huo, S.

Org. Lett. 2002, 4, 261-264.

(0) 307. (E)-1-Bromo-2-iodoethylene

Negishi, E.; Zeng, F.

In Encyclopedia of Reagents for Organic Synthesis, Paquette, L. A., Ed., John Wiley & Sons, Inc., New York, 2002.

(17) 308. A Highly Efficient, Selective, and General Method for the Synthesis of Conjugated (all-E)-Oligoenes of the (CH=CH)_n

Type via Iterative Hydrozirconation–Palladium- Catalyzed Cross-Coupling

Zeng, F.; Negishi, E.

Org. Lett. 2002, 4, 703-706.

(22) 309. Catalytic and Selective Conversion of (Z)-2-En-4-ynoic Acids to either 2H-Pyran-2-ones in the Presence of ZnBr₂ or

(Z)-5-Alkylidenefuran-2(5H)-ones in the Presence of Ag₂CO₃

Anastasia, L.; Xu, C.; Negishi, E.

Tetrahedron Lett. 2002, 43, 5673-5676.

(491) 310. Handbook of Organopalladium Chemistry for Organic Synthesis, 2 Vols.

Negishi, E., Ed., Wiley-Interscience, New York, 2002, 3279 pp.

311. Fundamental Properties of Palladium and Patterns of the Reactions of Palladium and Its

Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. I.2, 17-35.

312. General Discussion of the Methods of Synthesis and In-Situ Generation of Organopalladium Compounds

Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. II.3.1, 127-145.

313. Palladium-Catalyzed Aryl-Aryl Coupling

Anastasia, L.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.5, 311-334.

313. Palladium-Catalyzed Alkenyl-Aryl, Aryl-Alkenyl, and Alkenyl-Alkenyl Coupling

Reactions

Huo, S.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.6, 335-408.

315. Palladium-Catalyzed Alkynylation with Alkynylmetals or Alkynyl Electrophiles Negishi, E.; Xu, C.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.8.2, 531-549.

316. Palladium-Catalyzed Cross-Coupling between Allyl, Benzyl, or Propargyl Groups and Unsaturated Groups

Negishi, E.; Liu, F.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.9, 551-589.

317. Palladium-Catalyzed Cross-Coupling between Allyl-, Benzyl-, or Propargylmetals and Allyl, Benzyl, or Propargyl

Electrophiles

Negishi, E.; Liao, B.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.10, 591-596.

318. Palladium-Catalyzed Cross-Coupling Involving Saturated Alkylmetals

Negishi, E.; Gagneur, S.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.11.1, 597-618.

319. Palladium-Catalyzed Cross-Coupling between Homoallyl-, Homopropargyl-, or Homobenzylmetals and Alkenyl or Aryl

Electrophiles

Negishi, E.; Zeng, F.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.11.2, 619-633.

320. Palladium-Catalyzed α-Substitution Reactions of Enolates and Related Derivatives Other than the Tsuji-Trost Allylation

Reaction

Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.14.1, 693-719.

321. Palladium-Catalyzed Cross-Coupling Involving b-Hetero-Substituted Compounds Other than Enolates

Negishi, E.; Alimardanov, A.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.14.2, 721-766.

322. Palladium-Catalyzed Conjugate Substitution

Negishi, E.; Dumond, Y.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.15, 767-789.

323. Synthesis of Natural Products via Palladium-Catalyzed Cross-Coupling

Tan, Z.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. III.2.18, 863-942.

324. Palladium-Catalyzed Tandem and Cascade Carbopalladation of Alkynes and 1,1-Disubstituted Alkenes Terminated by

Carbonylative Reactions

Negishi, E.; Copéret, C.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. IV.3.3, 1431-1448.

325. Pd-Catalyzed Allylation and Related Substitution Reactions of Enolates and Related Derivatives of “Ordinary” Ketones,

and Aldehydes, and Other Carbonyl Compounds

Negishi, E.; Liou, S. Y.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. V.2.1.4, 1769-1793.

326. Synthesis of Natural Products via Nucleophilic Attack on p-Ligands of Palladium-Alkene,

Palladium-Alkyne, and Related p-Complexes

Xu, C.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. V.3.6, 2289-2305.

327. Reactions of Acylpalladium Derivatives with Enolates and Related Amphiphilic Reagents

Negishi, E.; Makabe, H.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. VI.2.3, 2455-2471.

328. Intramolecular Acylpalladation Reactions with Alkenes, Alkynes, and Related

Unsaturated Compounds

Copéret, C.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. VI.4.1.1, 2519-2552.

329. Palladium-Catalyzed Heterogeneous Hydrogenation

King, A. O.; Larsen, R. D.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. VII.2.1, 2719-2758.

330. Palladium-Catalyzed Isomerization of Alkenes, Alkynes, and Related Compounds without Skeletal Rearrangements

Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed., J. Wiley & Sons, New

York, 2002, Sect. VII.3, 2783-2788

331. Palladium-Catalyzed Hydrometallation

Makabe, H.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. VII.4, 2789-2823.

332. Other Palladium-Catalyzed or –Promoted Oxidation Reactions via 1,2- or 1,4-Elimination

Fujiwara, Y.; Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. VIII.3.3, 2895-2903.

333. Other Miscellaneous Palladium-Catalyzed or -Promoted Oxidation Reactions

Negishi, E.

In , Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. VIII.4, 2905-2912.

334. Palladium-Catalyzed Carbon Skeletal Rearrangements Other than [3, 3] Rearrangements

Negishi, E.

In The Handbook of Organopalladium Chemistry for Organic Synthesis, Negishi, E., Ed.,

J. Wiley & Sons, New York, 2002, Sect. IX.2.1.2, 2935-2938.

(7) 335. Organometallic Complexes of Zirconium and Hafnium

Negishi, E.; Takahashi, T.

Houben-Weyl, Science of Synthesis, Vol. 2, Imamoto, T.; Ed., Thieme, 2002, Chap. 2.11, 681-848.

(1) 336. (E)-1-Bromo-4-trimethylsilyl-1-buten-3-yne and (E)-1-Bromo-4-(tert-butyldimethylsilyl)- 1-buten-3-yne

Negishi, E.; Zeng, F.

Encyclopedia of Reagents for Organic Synthesis, Paquette, L. A., Ed., John Wiley & Sons, Inc., New York, 2002.

(24) 337. Highly Satisfactory Alkynylation of Alkenyl Halides via Pd-Catalyzed Cross-Coupling with Alkynylzincs and Its

Critical Comparison with the Sonogashira Alkynylation

Negishi, E.; Qian, M.; Zeng, F.; Anastasia, L.; Babinski, D.

Org. Lett. 2003, 5, 1597-1600.

(4) 338. Strictly “Pair”-Selective and Economical Synthesis of Conjugated Diynes via Pd-Catalyzed Reaction of Terminal

Alkynes with 1,1-Dichloroethylene, Elimination with LDA, and Subsequent Transformations

Qian, M.; Negishi, E.

Org. Process. Res. Dev., 2003, 1, 412-417.

(27) 339. Highly Selective Synthesis of (E)-3-Methyl-1-trialkylsilyl-3-en-1-ynes via trans-Selective Alkynylation Catalyzed by

Cl₂Pd(DPEphos) and Stereospecific Methylation with Methylzincs Catalyzed by Pd(^tBu₃P)₂

Shi, J.; Zeng, X.; Negishi, E.

Org. Lett., 2003, 5, 1825-1828.

(202) 340. Palladium-Catalyzed Alkynylation

Negishi, E.; Anastasia, L.

Chem. Rev., 2003, 103, 1979-2017

(22) 341. Clean Inversion of Configuration in the Pd-Catalyzed Cross-Coupling of

2-Bromo-1,3-dienes

Zeng, X.; Hu, Q.; Qian, M.; Negishi, E.

J. Am. Chem. Soc., 2003, 125, 13636-13637.

(12) 342. Pd-Catalyzed Selective Tandem Arylation of 1,1-Dihalo-1-alkenes with Aryl- and Alkylzinc Derivatives to Produce α-

Alkyl-substituted Styrene Derivatives

Shi, J.; Negishi, E.

J. Organomet. Chem., 2003, 687, 518-524.

(21) 343. Highly Stereoselective Synthesis of (1E)-2-Methyl-1,3-dienes by Palladium-Catalyzed trans-Selective Cross-Coupling of

1,1-Dibromo-1-alkenes with Alkenylzinc Reagents

Zeng, X.; Qian, M.; Hu, Q.; Negishi, E.

Angew. Chem. Int. Ed. 2004, 43, 2259-2263.

(18) 344. A New, Efficient, and General Route to Reduced Polypropionates via Zr-Catalyzed Asymmetric C–C Bond Formation

Negishi, E.; Tan, Z.; Liang, B.; Novak, T.

Proc. Natl. Acad. Sci. USA, 2004, 101, 5782-5787

(1) 345. Disasteroselective, Enantioselective, and Regioselective Carboalumination Reactions Catalyzed by Zirconocene

Derivatives

Negishi, E.; Tan, Z.

Topics in Organometallic Chemistry, Takahashi, T., Ed., Springer, 2005, 139-176.

(3) 346. Zr-Promoted “Pair”-selective and Regioselective Synthesis of Penta-substituted Benzene Derivatives

Dumond, Y. R.; Negishi, E.

Tetrahedron, 2004, 60, 1345-1352

(21) 347. An Efficient and General Method for the Synthesis of a,w-Difunctional Reduced Polypropionates by Zr-catalyzed

Asymmetric Carboalumination: Synthesis of the Scyphostatin Sidechain

Tan, Z.; Negishi, E.

Agnew. Chem. Int. Ed., 2004, 43, 2911-2914.

(22) 348. Efficient and Selective Synthesis of Siphonarienolone and Related Reduced Polypropionates via Zr-Catalyzed

Asymmetric Carboalumination

Magnin-Lachaux, M.; Tan, Z.; Liang, B.; Negishi, E.

Org. Lett., 2004, 6, 1425-1427.

(14) 349. Use of InCl₃ as a Cocatalyst and a Cl₂Pd(DPEphos)–P(2-Furyl)₃ Catalyst System for One-Pot Hydrometalation–

Cross-Coupling and Carbometalation–Cross-Coupling Tandem Processes

Qian, M.; Huang, Z.; Negishi, E.

Org. Lett., 2004, 6, 1531-1534.

(15) 350. Palladium- or Nickel-Catalyzed Cross-Coupling with Organometals Containing Zinc, Aluminum, and Zirconium: The

Negishi Coupling

Negishi, E.; Zeng, X.; Tan, Z.; Qian, M.; Hu, Q.; Huang, Z.; Babinski, D. J.

Metal-Catalyzed C–C and C–N Coupling Reactions, de Meijere, A.; Diederich, F., Eds.

Wiley-VCH, 2004, Chap. 15, p. 815-889.

(13) 351. Efficient and Selective Synthesis of 6,7-Dehydrostipiamide via Zr-Catalyzed Asymmetric Carboalumination and Pd-

Catalyzed Cross-Coupling of Organozincs

Zeng, X.; Zeng, F.; Negishi, E.

Org. Lett., 2004, 6, 3245-3248.

(17) 352. All-Catalytic, Efficient, and Asymmetric Synthesis of a,w-Diheterofunctional Reduced Polypropionates via “One-Pot”

Zr-Catalyzed Asymmetric Carboalumination-Pd-Catalyzed Cross-Coupling Tandem Process

Novak, T.; Tan, Z.; Liang, B.; Negishi, E.

J. Am. Chem. Soc., 2005, 127, 2838-2839.

(11) 353. Palladium-Catalyzed Cross-Coupling Reaction of Alkynylzincs with Benzylic Electrophiles

Qian, M.; Negishi, E.

Tetrahedron Lett., 2005, 46, 2927-2930.

(5) 354. Palladium-Catalyzed Cross-Coupling Reactions with Zinc, Boron, and Indium Exhibiting High Turnover Numbers

(TONs): Use of Bidentate Phosphines and Other Critical Factors in Achieving High TONs

Huang, Z.; Qian, M.; Babinski, D. T.; Negishi, E.

Organometallics, 2005, 24, 475-478.

(13) 355. A Quarter of a Century of Explorations in Organozirconium Chemistry

Negishi, E.

Dalton Trans. 2005, 827-848.

(0) 356 Di-n-butylbis(η⁵-cyclopentadienyl)zirconium

Negishi, E.; Novak T.

Electronic Encyclopedia of Reagents for Organic Synthesis. Paquette, L.A., Ed., John Wiley & Sons, Inc., New York,

2005.

(2) 357. Palladium-Catalyzed Cross-Coupling of Alkynylzincs with Allylic Electrophiles: An Efficient and Selective Synthesis

of Stereo- and Regio-Defined 1,4-Enynes

Qian, M.; Negishi, E.

Synlett, 2005, 1789-1793.

(4) 358. Palladium-Catalyzed trans-Selective Alkynylation-Alkylation Tandem Reaction of 1,1-Dihalo-1-alkenes for the Syntehsis

of (E)-3-Alkyl-1-trialkylsilyl-3-en-1-ynes

Negishi, E.; Shi, J.; Zeng, X

Tetrahedron, 2005, 61, 9886-9895.

(11) 359. Palladium-Catalyzed Alkenylation via Negishi Coupling

Negishi, E.; Hu, Q.; Huang, Z.; Qian, M.; Wang, G.

Aldrichim. Acta, 2005, 38, 71-88.

(0) 360