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Records 1 to 20 of 59
| Authors | Title | Journal | Year | Vol. |
Issue | Pages |
| Hahne, K.;Vervacke, J. S.;Shrestha, L.;Donelson, J. L.;Gibbs, R. A.;Distefano, M. D.;Hrycyna, C. A. | Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes | Biochemical and Biophysical Research Com | 2012 | 423 | - | 98-103 |
| Kuriakose, J.;Hrycyna, C. A.;Chmielewski, J. | Click chemistry-derived bivalent quinine inhibitors of P-glycoprotein-mediated cellular efflux | Bioorganic & Medicinal Chemistry Letters | 2012 | 22 | - | 4410-4412 |
| Namanja, H. A.;Emmert, D.;Davis, D. A.;Campos, C.;Miller, D. S.;Hrycyna, C. A.;Chmielewski, J. | Toward Eradicating HIV Reservoirs in the Brain: Inhibiting P-Glycoprotein at the Blood-Brain Barrier with Prodrug Abacavir Dimers | Journal of the American Chemical Society | 2012 | 134 | - | 2976-2980 |
| Griggs, A. M.;Hahne, K.;Hrycyna, C. A. | Functional Oligomerization of the Saccharomyces cerevisiae Isoprenylcysteine Carboxyl Methyltransferase, Ste14p | Journal of Biological Chemistry | 2010 | 285 | 18 | 13380-13387 |
| Pires M. M.;Emmert, D.;Hrycyna, C. A.;Chmielewski, J. | Inhibition of P-Glycoprotein-Mediated Paclitaxel Resistance by Reversibly Linked Quinine Homodimers | Molecular Pharmacology | 2009 | 75 | - | 92-100 |
| Donelson J. L.;Hodges-Loaiza, H. B.;Henriksen, B. S.;Hrycyna, C. A.;Gibbs, R. A. | Solid-Phase Synthesis of Prenylcysteine Analogs | Journal of Organic Chemistry | 2009 | 74 | - | 2975-2981 |
| Coffinier C.;Hudon, S. E.;Lee, R.;Farber, E. A.;Nobumori, C.;Miner, J. H.;Andres, D. A.;Spielmann, H. P.;Hrycyna, C. A.;Fong, L. G.;Young, S. G. | A potent HIV protease inhibitor, darunavir, does not inhibit ZMPSTE24 or lead to an accumulation of farnesyl-prelamin A in cells | Journal of Biological Chemistry | 2008 | 283 | - | 9797-9804 |
| Hudon S. E.;Coffinier, C.;Michaelis, S.;Fong, L. G.;Young, S. G.;Hrycyna, C. A. | HIV-protease inhibitors block the enzymatic activity of purified Ste24p | Biochemical and Biophysical Research Com | 2008 | 374 | - | 365-368 |
| Coffinier C.;Hudon, S. E.;Farber, E. A.;Chang, S. Y.;Hrycyna, C. A.;Young, S. G.;Forg, L. G. | HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells | Proceedings of the National Academy of S | 2007 | 104 | - | 13432-13437 |
| Takenaka K.;Morgan, J. A.;Scheffer, G. L.;Adachi, M.;Stewart, C. F.;Sun, D.;Leggas, M.;Ejendal, K. F. K.;Hrycyna, C. A.;Schuetz, J. D. | Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution | Cancer Research | 2007 | 67 | - | 6965-6972 |
| Donelson J. L.;Hodges, H. B.;MacDougall, D. D.;Henriksen, B. S.;Hrycyna, C. A.;Gibbs, R. A. | Amide-substituted farnesylcysteine analogs as inhibitors of human isoprenylcysteine carboxyl methyltransferase | Bioorganic & Medicinal Chemistry Letters | 2006 | 16 | - | 4420-4423 |
| Ejendal K. F. K.;Diop, N. K.;Schweiger, L. C.;Hrycyna, C. A. | The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding | Protein Science | 2006 | 15 | - | 1597-1607 |
| Anderson J. L.;Henriksen, B. S.;Gibbs, R. A.;Hrycyna, C. A. | The isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase - Development of novel inhibitors | Journal of Biological Chemistry | 2005 | 280 | - | 29454-29461 |
| Bhatia A.;Schafer, H. J.;Hrycyna, C. A. | Oligomerization of the human ABC transporter ABCG2: Evaluation of the native protein and chimeric dimers | Biochemistry | 2005 | 44 | - | 10893-10904 |
| Geisler M.;Blakeslee, J. J.;Bouchard, R.;Lee, O. R.;Vincenzetti, V.;Bandyopadhyay, A.;Titapiwatanakun, B.;Peer, W. A.;Bailly, A.;Richards, E. L.;Ejenda, K. F. K.;Smith, A. P.;Baroux, C.;Grossniklaus, U.;Muller, A.;Hrycyna, C. A.;Dudler, R.;Murphy, A. S.; | Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1 | Plant Journal | 2005 | 44 | - | 179-194 |
| Henriksen B. S.;Anderson, J. L.;Hrycyna, C. A.;Gibbs, R. A. | Synthesis of desthio prenyleysteine analogs: Sulfur is important for biological activity | Bioorganic & Medicinal Chemistry Letters | 2005 | 15 | - | 5080-5083 |
| Hodges H. B.;Zhou, M. K.;Haldar, S.;Anderson, J. L.;Thompson, D. H.;Hrycyna, C. A. | Inhibition of membrane-associated methyltransferases by a cholesterol-based metal chelator | Bioconjugate Chemistry | 2005 | 16 | - | 490-493 |
| Wang C. H.;Leffler, S.;Thompson, D. H.;Hrycyna, C. A. | A general fluorescence-based coupled assay for S-adenosylmethionine-dependent methyltransferases | Biochemical and Biophysical Research Com | 2005 | 331 | - | 351-356 |
| Corrigan D. P.;Kuszczak, D.;Rusinol, A. E.;Thewke, D. P.;Hrycyna, C. A.;Michaelis, S.;Sinensky, M. S. | Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24 | Biochemical Journal | 2005 | 387 | - | 129-138 |
| Diop N. K.;Hrycyna, C. A. | N-linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane | Biochemistry | 2005 | 44 | - | 5420-5429 |
