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Records 21 to 40 of 59
| Authors | Title | Journal | Year | Vol. |
Issue | Pages |
| Anderson J. L.;Frase, H.;Michaelis, S.;Hrycyna, C. A. | Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p | Journal of Biological Chemistry | 2005 | 280 | - | 7336-7345 |
| Ejendal K. F. K.;Hrycyna, C. A. | Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A | Molecular Pharmacology | 2005 | 67 | - | 902-911 |
| Henriksen B. S.;Anderson, J. L.;Hrycyna, C. A.;Gibbs, R. A. | SAR studies of AFC-based icmt inhibitors. | Abstracts of Papers of the American Chem | 2004 | 227 | - | U28-U28 |
| Anderson J. L.;Frase, H.;Laurence, J.;Michaelis, S.;Hrycyna, C. A. | Molecular mechanisms of Ras isoprenylcysteine carboxyl methyltransferase (ICMT) | Mol. Biol. Cell | 2002 | 13 | - | 499A-499A |
| Ejendal K. F. K.;Hrycyna, C. A. | Multidrug resistance and cancer: The role of the human ABC transporter ABCG2 | Curr. Protein Pept. Sci. | 2002 | 3 | - | 503-511 |
| Honjo Y.;Hrycyna, C. A.;Yan, Q. W.;Medina-Perez, W. Y.;Robey, R. W.;van de Laar, A.;Litman, T.;Dean, M.;Bates, S. E. | Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells | Cancer Res. | 2001 | 61 | - | 6635-6639 |
| Hrycyna C. A. | Molecular genetic analysis and biochemical characterization of mammalian P-glycoproteins involved in multidrug resistance | Semin. Cell Dev. Biol. | 2001 | 12 | - | 247-256 |
| Tarasova N. I.;Amadei, G.;Seth, R.;Hrycyna, C.;Gottesman, M.;Michejda, C. | New paradigm for the development of inhibitors of ABC transporters and other polytopic membrane proteins | Clin. Cancer Res. | 2001 | 7 | - | 3738S-3738S |
| Lamensdorf I.;Hrycyna, C.;He, L. P.;Nechushtan, A.;Tjurmina, O.;Harvey-White, J.;Eisenhofer, G.;Rojas, E.;Kopin, I. J. | Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter | Naunyn-Schmiedebergs Arch. Pharmacol. | 2000 | 361 | - | 654-664 |
| Gribar J. J.;Ramachandra, M.;Hrycyna, C. A.;Dey, S.;Ambudkar, S. V. | Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system | J. Membr. Biol. | 2000 | 173 | - | 203-214 |
| Ambudkar S. V.;Dey, S.;Hrycyna, C. A.;Ramachandra, M.;Pastan, I.;Gottesman, M. M. | Biochemical, cellular, and pharmacological aspects of the multidrug transporter | Annu. Rev. Pharmacol. Toxicol. | 1999 | 39 | - | 361-398 |
| Hrycyna C. A.;Ramachandra, M.;Germann, U. A.;Cheng, P. W.;Pastan, I.;Gottesman, M. M. | Both ATP sites of human P-glycoprotein are essential but not symmetric | Biochemistry | 1999 | 38 | - | 13887-13899 |
| Hrycyna C. A.;Ramachandra, M.;Ambudkar, S. V.;Ko, Y. H.;Pedersen, P. L.;Pastan, I.;Gottesman, M. M. | Mechanism of action of human P-glycoprotein ATPase activity - Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites | J. Biol. Chem. | 1998 | 273 | - | 16631-16634 |
| Hrycyna C. A.;Gottesman, M. M. | Multidrug ABC transporters from bacteria to man: an emerging hypothesis for the universality of molecular mechanism and function | Drug Resist. Update | 1998 | 1 | - | 81-83 |
| Hrycyna C. A.;Ramachandra, M.;Pastan, I.;Gottesman, M. M. | Functional expression of human P-glycoprotein from plasmids using vaccinia virus bacteriophage T7 RNA polymerase system | - |
1998 | 292 | - | 456-473 |
| Hafkemeyer P.;Dey, S.;Ambudkar, S. V.;Hrycyna, C. A.;Pastan, I.;Gottesman, M. M. | Contribution to substrate specificity and transport of nonconserved residues in transmembrane domain 12 of human P-glycoprotein | Biochemistry | 1998 | 37 | - | 16400-16409 |
| Hrycyna C. A.;Airan, L. E.;Germann, U. A.;Ambudkar, S. V.;Pastan, I.;Gottesman, M. M. | Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport | Biochemistry | 1998 | 37 | - | 13660-13673 |
| Ramachandra M.;Ambudkar, S. V.;Chen, D.;Hrycyna, C. A.;Dey, S.;Gottesman, M. M.;Pastan, I. | Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state | Biochemistry | 1998 | 37 | - | 5010-5019 |
| Gottesman M. M.;Hrycyna, C. A.;Hafkemeyer, P.;Dey, S.;Zhou, Y.;Shoshani, T.;Pastan, I. | Molecular dissection of the multidrug transporter | Naunyn-Schmiedebergs Arch. Pharmacol. | 1998 | 358 | - | R24-R24 |
| Russ G.;Ramachandra, M.;Hrycyna, C. A.;Gottesman, M. M.;Pastan, I.;Bennink, J. R.;Yewdell, J. W. | P-glycoprotein plays an insignificant role in the presentation of antigenic peptides to CD8+ T cells | Cancer Res. | 1998 | 58 | - | 4688-4693 |