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Records 41 to 60 of 63

Authors Title Journal Year

Vol.

 Issue

Pages
Witucki L. A.;Huang, X.;Shah, K.;Liu, Y.;Kyin, S.;Eck, M. J.;Shokat, K. M. Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme Chem. Biol. 2002 9 - 25-33
Shah K.;Shokat, K. M. A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway Chem. Biol. 2002 9 - 35-47
Wang Z. Y.;Shah, K.;Rana, T. M. Probing Tat peptide-TAR RNA interactions by psoralen photo-cross-linking Biochemistry 2001 40 - 6458-6464
Habelhah H, Shah K, Huang L, Ostareck-Lederer A, Burlingame AL, Shokat KM, Hentze MW, Ronai Z ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nat Cell Biol 2001 3(3) - 325-30
Habelhah H, Shah K, Huang L, Burlingame AL, Shokat KM, Ronai Z. Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. J Biol Chem 2001 276(21) - 18090-5
Ulrich S. M.;Buzko, O.;Shah, K.;Shokat, K. M. Towards the engineering of an orthogonal protein kinase/nucleotide triphosphate pair Tetrahedron 2000 56 - 9495-9502
Liu Y.;Witucki, L. A.;Shah, K.;Bishop, A. C.;Shokat, K. M. Src-Abl tyrosine kinase chimeras: Replacement of the adenine binding pocket of c-Abl with v-Src to swap nucleotide and inhibitor specificities Biochemistry 2000 39 - 14400-14408
Bishop A.;Buzko, O.;Heyeck-Dumas, S.;Jung, I.;Kraybill, B.;Liu, Y.;Shah, K.;Ulrich, S.;Witucki, L.;Yang, F.;Zhang, C.;Shokat, K. M. Unnatural ligands for engineered proteins: New tools for chemical genetics Annu. Rev. Biophys. Biomolec. Struct. 2000 29 - 577-606
Bishop A. C.;Kung, C. Y.;Shah, K.;Witucki, L.;Shokat, K. M.;Liu, Y. Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach J. Am. Chem. Soc. 1999 121 - 627-631
Bishop A. C.;Shah, K.;Liu, Y.;Witucki, L.;Kung, C. Y.;Shokat, K. M. Design of allele-specific inhibitors to probe protein kinase signaling Curr. Biol. 1998 8 - 257-266
Liu Y.;Shah, K.;Yang, F.;Witucki, L.;Shokat, K. M. A molecular gate which controls unnatural ATP analogue recognition by the tyrosine kinase v-Src Bioorg. Med. Chem. 1998 6 - 1219-1226
Liu Y.;Shah, K.;Yang, F.;Witucki, L.;Shokat, K. M. Engineering Src family protein kinases with unnatural nucleotide specificity Chem. Biol. 1998 5 - 91-101
Shah K.;Liu, Y.;Deirmengian, C.;Shokat, K. M. Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates Proc. Natl. Acad. Sci. U. S. A. 1997 94 - 3565-3570
Shah K.;Neenhold, H.;Wang, Z. Y.;Rana, T. M. Incorporation of an artificial protease and nuclease at the HIV-1 Tat binding site of trans-activation responsive RNA Bioconjugate Chem. 1996 7 - 283-289
Shah K.;Rana, T. M. Synthesis of N-alpha-Fmoc-N-epsilon-tetrabutyl ester-EDTA-L-Lysine: An amino acid analog to prepare affinity cleaving peptides Synth. Commun. 1996 26 - 2695-2702
Shah K.;Wu, H. Y.;Rana, T. M. Synthesis of Uridine Phosphoramidite Analogs - Reagents for Site-Specific Incorporation of Photoreactive Sites into Rna Sequences Bioconjugate Chem. 1994 5 - 508-512
Karle IL, Ranganathan D, Shah K, Vaish NK Conformation of the oxalamide group in retro-bispeptides. Three crystal structures Int J Pept Protein Res 1994 43(2) - 160-5.
Ranganathan D., Vaish N.K., Shah K. Protein backbone Modification by Novel C-C side chain scission J am Chem soc 1994 116 - 6545-6557
Ranganathan D., Vaish N.K., Shah K., Roy R., Madhusudanan K.P. Oxalopeptides as core motifs for protein design J Chem Soc Chem Commun 1993 - - 92-94
Bhattacharya I, Shah K, Vankar PS, Vankar, YD A convenient synthesis of vinyl epoxides from glycidic esters via a-hydroxy-b,g-unsaturated esters Synth Commun 1993 23 - 2405-2407