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Records 21 to 40 of 69

Authors Title Journal Year

Vol.

Issue

Pages

Ghosh A. K.;Shurrush, K.;Kulkarni, S. Asymmetric Synthesis of anti-Aldol Segments via a Nonaldol Route: Synthetic Applications to Statines and (-)-Tetrahydrolipstatin Journal of Organic Chemistry 2009 74 - 4508-4518
Ghosh A. K.;Xu, C. X. A Convergent Synthesis of the Proposed Structure of Antitumor Depsipeptide Stereocalpin A Organic Letters 2009 11 - 1963-1966
Ghosh A. K. Harnessing Nature's Insight: Design of Aspartyl Protease Inhibitors from Treatment of Drug-Resistant HIV to Alzheimer's Disease' Journal of Medicinal Chemistry 2009 52 - 2163-2176
Ghosh A. K.;Yuan, H. Stereoselective synthesis of the C-1-C-12 segment of iriomoteolide-1a: a very potent macrolide antitumor agent Tetrahedron Letters 2009 50 - 1416-1418
Koh Y.;Das, D.;Leschenko, S.;Nakata, H.;Ogata-Aoki, H.;Amano, M.;Nakayama, M.;Ghosh, A. K.;Mitsuya, H. GRL-02031, a Novel Nonpeptidic Protease Inhibitor (PI) Containing a Stereochemically Defined Fused Cyclopentanyltetrahydrofuran Potent against Multi-PI-Resistant Human Immunodeficiency Virus Type 1 In Vitro Antimicrobial Agents and Chemotherapy 2009 53 - 997-1006
Ghosh A. K.;Xi, K. Total Synthesis of (-)-Platensimycin, a Novel Antibacterial Agent Journal of Organic Chemistry 2009 74 - 1163-1170
Ghosh A. K.;Gemma, S.;Tang, J. beta-secretase as a therapeutic target for Alzheimer's disease Neurotherapeutics 2008 5 - 399-408
Ghosh A. K.;Kulkarni, S. S.;Xu, C. X.;Shurrush, K. Asymmetric multicomponent reactions: convenient access to acyclic stereocenters and functionalized cyclopentenoids Tetrahedron-Asymmetry 2008 19 - 1020-1026
Ghosh A. K.;Takayama, J. Enantioselective synthesis of cyclopentyltetrahydrofuran (Cp-THF), an important high-affinity P2-ligand for HIV-1 protease inhibitors Tetrahedron Letters 2008 49 - 3409-3412
Ghosh A. K.;Kumaragurubaran, N.;Hong, L.;Koelsh, G.;Tang, J. Memapsin 2 (beta-secretase) inhibitors: Drug development Current Alzheimer Research 2008 5 - 121-131
Ghosh A. K.;Kumaragurubarana, N.;Hong, L.;Kulkarni, S.;Xu, X. M.;Miller, H. B.;Reddy, D. S.;Weerasena, V.;Turner, R.;Chang, W.;Koelsch, G.;Tang, J. Potent memapsin 2 (beta-secretase) inhibitors: Design, synthesis, protein-ligand X-ray structure, and in vivo evaluation Bioorganic & Medicinal Chemistry Letters 2008 18 - 1031-1036
Ghosh A. K.;Xu, X.;Kim, J. H.;Xu, C. X. Enantioselective total synthesis of peloruside A: A potent microtubule stabilizer Organic Letters 2008 10 - 1001-1004
Liu F. L.;Kovalevsky, A. Y.;Tie, Y. F.;Ghosh, A. K.;Harrison, R. W.;Weber, I. T. Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir Journal of Molecular Biology 2008 381 - 102-115
Royston E.;Ghosh, A.;Kofinas, P.;Harris, M. T.;Culver, J. N. Self-assembly of virus-structured high surface area nanomaterials and their application as battery electrodes Langmuir 2008 24 - 906-912
Sinan M.;Panda, M.;Ghosh, A.;Dhara, K.;Fanwick, P. E.;Chattopadhyay, D. J.;Goswami, S. Mild synthesis of a family of planar triazinium cations via proton-assisted cyclization of pyridyl containing azo compounds and studies on DNA intercalation Journal of the American Chemical Society 2008 130 - 5185-5193
Zhang Y. W.;Hamel, E.;Ghosh, A. K.;Pommier, Y. The marine compound Lasonolide A is a potent inducer of premature chromosome condensation and inhibitor of cell adhesion Molecular Cancer Therapeutics 2007 6 - 3544s-3544s
Ghosh A. K.;Dawson, Z. L.;Mitsuya, H. Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV Bioorganic & Medicinal Chemistry 2007 15 - 7576-7580
Ghosh A. K.;Gong, G. L. Enantioselective total synthesis of macrolide antitumor agent (-)-lasonolide A Organic Letters 2007 9 - 1437-1440
Tie Y. F.;Kovalevsky, A. Y.;Boross, P.;Wang, Y. F.;Ghosh, A. K.;Tozser, J.;Harrison, R. W.;Weber, I. T. Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir Proteins-Structure Function and Bioinfor 2007 67 - 232-242
Ghosh A. K.;Xi, K. Enantioselective synthesis of (-)-platensimycin oxatetracyclic core by using an intramolecular Diels-Alder reaction Organic Letters 2007 9 - 4013-4016