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Records 41 to 60 of 69
| Authors | Title | Journal | Year | Vol. |
Issue | Pages |
| Koh Y.;Matsumi, S.;Das, D.;Amano, M.;Davis, D. A.;Li, J. F.;Leschenko, S.;Baldridge, A.;Shioda, T.;Yarchoan, R.;Ghosh, A. K.;Mitsuya, H. | Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization | Journal of Biological Chemistry | 2007 | 282 | - | 28709-28720 |
| Wang Y. F.;Tie, Y. F.;Boross, P. I.;Tozser, J.;Ghosh, A. K.;Harrison, R. W.;Weber, I. T. | Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease | Journal of Medicinal Chemistry | 2007 | 50 | - | 4509-4515 |
| Amano M.;Koh, Y.;Das, D.;Li, J. F.;Leschenko, S.;Wang, Y. F.;Boross, P. I.;Weber, I. T.;Ghosh, A. K.;Mitsuya, H. | A novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI), GRL-98065, is potent against multiple-PI-resistant human immunodeficiency virus in vitro | Antimicrobial Agents and Chemotherapy | 2007 | 51 | - | 2143-2155 |
| Ghosh A. K.;Moon, D. K. | Enantioselective total synthesis of (+)-jasplakinolide | Organic Letters | 2007 | 9 | - | 2425-2427 |
| Ghosh A. K.;Kumaragurubaran, N.;Hong, L.;Kulkarni, S. S.;Xu, X. M.;Chang, W. P.;Weerasena, V.;Turner, R.;Koelsch, G.;Bilcer, G.;Tang, J. | Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands | Journal of Medicinal Chemistry | 2007 | 50 | - | 2399-2407 |
| Ghosh A. K.;Xi, K.;Johnson, M. E.;Baker, S. C.;Mesecar, A. D. | Progress in anti-SARS coronavirus chemistry, biology and chemotherapy | Annual Reports in Medicinal Chemistry, V | 2006 | 41 | - | 183-196 |
| A. K. Ghosh, G. Gong | Total Synthesis and Revision of C6 Stereochemistry of (+)-Amphidinolide W. | J. Org. Chem. | 2006 | 71 | - | 1085-95 |
| Ghosh A. K.;Schiltz, G.;Perali, R. S.;Leshchenko, S.;Kay, S.;Walters, D. E.;Koh, Y.;Maeda, K.;Mitsuya, H. | Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P-2 '-ligands | Bioorganic & Medicinal Chemistry Letters | 2006 | 16 | - | 1869-1873 |
| Ghosh A. K.;Kumaragurubaran, N.;Hong, L.;Lei, H.;Hussain, K. A.;Liu, C. F.;Devasamudram, T.;Weerasena, V.;Turner, R.;Koelsch, G.;Bilcer, G.;Tang, J. | Design, synthesis and X-ray structure of protein-ligand complexes: Important insight into selectivity of memapsin 2 (beta-secretase) inhibitors | Journal of the American Chemical Society | 2006 | 128 | - | 5310-5311 |
| Kovalevsky A. Y.;Tie, Y. F.;Liu, F. L.;Boross, P. I.;Wang, Y. F.;Leshchenko, S.;Ghosh, A. K.;Harrison, R. W.;Weber, I. T. | Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M | Journal of Medicinal Chemistry | 2006 | 49 | - | 1379-1387 |
| Chang W. P.;Huang, X. P.;Koelsch, G.;Hong, L.;Ghosh, A. K.;Tang, J. | Beta-secretase inhibitor drug, between fantasy and reality | Neurobiology of Aging | 2006 | 27 | - | S20-S20 |
| Ghosh A. K.;Sridhar, P. R.;Leshchenko, S.;Hussain, A. K.;Li, J. F.;Kovalevsky, A. Y.;Walters, D. E.;Wedekind, J. E.;Grum-Tokars, V.;Das, D.;Koh, Y.;Maeda, K.;Gatanaga, H.;Weber, I. T.;Mitsuya, H. | Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance | Journal of Medicinal Chemistry | 2006 | 49 | - | 5252-5261 |
| Ghosh A. K.;Xi, K.;Ratia, K.;Santarsiero, B. D.;Fu, W. T.;Harcourt, B. H.;Rota, P. A.;Baker, S. C.;Johnson, M. E.;Mesecar, A. D. | Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors | Journal of Medicinal Chemistry | 2005 | 48 | - | 6767-6771 |
| Ghosh A. K.;Kumaragurubaran, N.;Tang, J. | Recent developments of structure based beta-secretase inhibitors for Alzheimer's disease | Current Topics in Medicinal Chemistry | 2005 | 5 | - | 1609-1622 |
| A. K. Ghosh, T. Devasamudram, L. Hong, C. DeZutter, X. Xu, V. Weerasena, G. Koelsch, G. Bilcer, and J. Tang | Structure Based Design of Cycloamide-urethane-Derived Novel Inhibitors of Human Brain Memapsin 2 (b-Secretase) | Bioorg. Med. Chem. Lett. | 2005 | 15 | - | 15-20 |
| R. T. Turner, L. Hong, G. Koelsch, A. K. Ghosh and J. Tang | Memapsin 2 (b-Secretase) New Subsites S5, S6 and S7: Structural Locations and Functional Roles | Biochemistry | 2005 | 44 | - | 105-12 |
| A. K. Ghosh, C-X, Xu, D. Wink | TiCl4 Promoted Multicomponent Reaction: a New Entry to the Functionalized a--Amino Acids | Org. Lett | 2005 | 7 | - | 7-10 |
| A. K. Ghosh, S. Leshchenko and M. Noetzel | Stereoselective Photochemical 1,3-Dioxalene Addition to a, b-Unsaturated–g-lactone: Synthesis of Bis-tetrahydrofuranyl Ligand for HIV Protease Inhibitor UIC-94-017 (TMC-114) | J. Org. Chem. | 2004 | 69 | - | 7822-29 |
| A. K. Ghosh and Gangli Gong | Total Synthesis and Structural Revision of (+)-Amphidinolide W | J. Am. Chem. Soc. | 2004 | 126 | - | 3704-05 |
| A. K. Ghosh, Jae-hun Kim | Stereoselective Chloroacetate Aldol Reaction: Synthesis of Acetate Aldol equivalents and Darzens Glycidic Esters | Org. Lett. | 2004 | 6 | - | 2725-8 |
