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Records 1 to 20 of 26
| Authors | Title | Journal | Year | Vol. |
Issue | Pages |
| Davies CW, Chaney J, Korbel, G, Ringe, D, Ploegh, H, Petsko GA and Das C* | The co-crystal Structure of Ubiquitin Carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK) | Bioorganic and Medicinal Chemistry Letters | 2012 | in press | ||
| Boudreaux D, Chaney J, Maiti T and Das C* | Contribution of active-site glutamine to rate enhancement in ubiquitin carboxy terminal hydrolases | FEBS Journal | 2012 | 279 | 1106-1118 | |
| Davies CW, Paul LN, Kim M and Das C* | Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability | Journal of Molecular Biology | 2011 | 413 | 416-29 | |
| Andersson FI, McMorran L, Werrell EF, Crone WJ, Das C, Hsu SD and Jackson SE | The Effect of Parkinson’s Disease Associated Mutations on the Stability, Structure and Dynamics of the Deubiquitinating Enzyme UCH-L1 | Journal of Molecular Biology | 2011 | 407 | 261-271 | |
| Maiti, T. K.;Permaul, M.;Boudreaux, D. A.;Mahanic, C.;Mauney, S.;Das, C. | Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme | Febs Journal | 2011 | 278 | 24 | 4917-4926 |
| Boudreaux, D. A.;Maiti, T. K.;Davies, C. W.;Das, C. | Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation | Proceedings of the National Academy of Sciences of | 2010 | 107 | 20 | 9117-9122 |
| Das, C.; Hoang, Q.Q.; Kreinbring, C.A.; Luchansky, S.J.; Meray, R.K. Ray, S.S.; Lansbury, P.T. Ringe, D.; Petsko, G.A. | Structural basis of conformational plasticity of the Parkinson’s disease- associated ubiquitin hydrolase UCH-L1 | Proceedings of the National Academy of Sciences USA | 2006 | 103 | - | 4675-4680 |
| Kornilova A.Y.; Bihel, F.; Das, C.; Wolfe, M.S. | The initial substrate-binding site of gamma-secretase is located on presenilin near the active site | Proceedings of the National Academy of Sciences USA | 2005 | 102 | - | 3230-3235. |
| Bihel F, Das C, Bowman MJ, Wolfe MS. | Discovery of a Subnanomolar helical D-tridecapeptide inhibitor of gamma-secretase. | J Med Chem. | 2004 | 47 | - | 3931-3933 |
| Esler WP, Das C, Wolfe MS. | Probing pockets S2-S4' of the gamma-secretase active site with (hydroxyethyl)urea peptidomimetics. | Bioorg Med Chem Lett. | 2004 | 14 | - | 1935-1938. |
| Aravinda S, Harini VV, Shamala N, Das C, Balaram P. | Structure and assembly of designed beta-hairpin peptides in crystals as models for beta-sheet aggregation. | Biochemistry | 2004 | 43 | - | 1832-1846. |
| Kornilova AY, Das C, Wolfe MS. | Differential effects of inhibitors on the gamma-secretase complex. Mechanistic implications. | J Biol Chem. | 2003 | 278 | - | 16470-16473. |
| Aravinda S, Shamala N, Das C, Sriranjini A, Karle IL, Balaram P. | Aromatic-aromatic interactions in crystal structures of helical peptide scaffolds containing projecting phenylalanine residues. | J Am Chem Soc. | 2003 | 125 | - | 5308-5315. |
| Das, C.; Berezovska, O.; Diehl, T.S.; Genet, C.; Buldyrev, I.; Tsai, J.Y.; Hyman, B.T.;Wolfe, M.S. | Designed helical peptides inhibit an intramembrane protease | Journal of the American Chemical Society | 2003 | 125 | - | 11794-11795. |
| Wolfe MS, Esler WP, Das C. | Continuing strategies for inhibiting Alzheimer's gamma-secretase. | J Mol Neurosci. | 2002 | 19 | - | 83-87. |
| Aravinda S, Shamala N, Das C, Balaram P. | Structural analysis of peptide helices containing centrally positioned lactic acid residues. | Biopolymers. | 2002 | 64 | - | 255-267. |
| Esler WP, Das C, Campbell WA, Kimberly WT, Kornilova AY, Diehl TS, Ye W, Ostaszewski BL, Xia W, Selkoe DJ, Wolfe MS. | Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase. | Nat Cell Biol. | 2002 | 4 | - | E110-E111. |
| Das, C.; Shankaramma, S.C.; Balaram, P. | Molecular carpentry: piecing together helices and hairpins in designed peptides. | Chemistry- A European Journal | 2001 | 7 | - | 840-847. |
| Das, C.; Naganagowda, G.A.; Karle, I.L. Balaram, P. | Designed beta-hairpin peptides with defined tight turn stereochemistry. | Biopolymers | 2001 | 58 | - | 335-346. |
| Karle IL, Das C, Balaram P | Effects of hydrogen-bond deletion on peptide helices: structural characterization of depsipeptides containing lactic acid | Biopolymers | 2001 | 59 | 276-289 |
