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Ghosh, A. K.;Takayama, J.;Rao, K. V.;Ratia, K.;Chaudhuri, R.;Mulhearn, D. C.;Lee, H.;Nichols, D. B.;Baliji, S.;Baker, S. C.;Johnson, M. E.;Mesecar, A. D. Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation Journal of Medicinal Chemistry 2010 53 13 4968-4979
Wubben TJ, Mesecar AD. Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacteriumtuberculosis. J Mol Biol 2010 404(2) 202-19
Ratia K, Pegan S, Takayama J, Sleeman K, Coughlin M, Baliji S, Chaudhuri R, Fu W, Prabhakar BS, Johnson ME, Baker SC, Ghosh AK, Mesecar AD. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci USA 2008 105(42) 16119-24
Ratia K, Saikatendu KS, Santarsiero BD, Barretto N, Baker SC, Stevens RC, Mesecar AD. Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Proc Natl Acad Sci USA 2006 103(15) 5717-22
Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD Modifying specific cysteines of the electrophile sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc Natl Acad Sci USA 2005 102(29) 10070-5