Our group is also active in the development of new types of instrumentation for various bioanalytical magnetic resonance applications. For example students in the group have constructed a number of novel NMR probes that are useful in a variety of applications, from small volume biofluid analysis using solenoidal microcoils, to high-throughput small-molecule NMR with our multiple-sample probe. More recently we have developed a HPLC-NMR system capable of performing separation, preconcentration and NMR analysis in succession. Continuing efforts focus on the increase in sensitivity and throughput of routine NMR analyses. There are a number of opportunities for students to participate in new and ongoing instrumentation projects, including hardware and software development.
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