Raftery Group, Purdue University Purdue University

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Bioanalytical NMR

LC-TQMS setup with CTC PAL temperature controlled autosampler equipped with four injection valves (Leap Technologies).

Method development in Agilent 1100 LC system

 
Our group is also active in the development of new types of instrumentation for various bioanalytical magnetic resonance applications. For example students in the group have constructed a number of novel NMR probes that are useful in a variety of applications, from small volume biofluid analysis using solenoidal microcoils, to high-throughput small-molecule NMR with our multiple-sample probe. More recently we have developed a HPLC-NMR system capable of performing separation, preconcentration and NMR analysis in succession. Continuing efforts focus on the increase in sensitivity and throughput of routine NMR analyses. There are a number of opportunities for students to participate in new and ongoing instrumentation projects, including hardware and software development.

[More on LC-MS-NMR-]
[More on Probe Design-]
 
 
Testing of microcoil probes for a variety of applications.

300MHz Varian INOVA and 500 MHz Bruker Avance DRX for microcoil probe testing, LC-NMR Hyphenation and bio-fluid analysis.