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| Oxford 500MHz magnet with home-built console. |
- 500 MHz Oxford NMR magnet - named as "El Jefe"
- Bruker Avance DRX 500 console
- Application: Home-built NMR probe tests, LC-MS-NMR Hyphenation, Metabolite Structural Analysis
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| Varian INOVA 300 with LC-NMR setup shown at the left. |
- "Lizzy" - a Varian INOVA 300MHz spectrometer
- Application: probe testings and LC-NMR Hyphenation
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| Bruker Avance 500MHz Spectrometer with cryoprobe. |
- RX 500-1 Bruker Avance spectrometer (Purdue Interdepartmental NMR Facility)
- Equipped with a 5mm cryoprobe with 1H sensitivity > 3000:1
- Used heavily for routine NMR in our metabolomics projects
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| Bruker DRX 500-2 spectrometer located in the Heine Pharmacy Bldg. |
- Another PINMRF instrument - DRX 500-2
- Equipped with TXI and BBO probes
- Provide excellent sensitivity, and broadband tunability for our multidimensional NMR experiments.
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| Bruker Avance III 800MHz NMR located in the Purdue NMR Facility |
- Bruker Avance III 800MHz NMR spectrometer at PINMRF
- Extends the sensitivity and resolution of experiments for a number of projects related to our ongoing Metabalomics research.
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| CMX 400 spectrometer for solids experiments. |
- CMX-400 at PINMRF
- equipped with a variety of static and MAS probes, from 2.5 mm to 7.5 mm . High rate spinning and broadband tunability
- Used extensively in our 129Xe optical pumping research, as well as metabolite studies on whole tissue samples and extracts
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LCMS system automated sample handler and temperature controller |
- Sciex API 3000 Triple Quad with Turbo-electrospray ionizer
- Two quaternary Agilent 1100 LC pumps two columns in temperature controlled oven system and CTC PAL temperarture controlled autosampler
- Application: LCTQMS system currently being used for targetted studies of metabolites in cancer tissues
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| Finnigan ESI-MS for use in metabolomics studies. |
- The Finnigan MS quadrupole ion trap instrument with an electrospray source
- Used in the mass analysis of metabolites in biological fluids, and used in the investigation of metabolic perturbations through correlation with complimentary NMR data
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| Agilent 1100 temperature controlled LC system |
- Agilent 1100 LC system with quaternary pumps
- Widely used for method development for the separation of urine and serum samples before NMR or MS analysis
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| Shimadzu LC interfaced to our 300MHz NMR. |
- Shimadzu LC system in-line with a microcoil probe in our 300MHz INOVA instrument
- Custom LabVIEW-controlled valving setup (in black in photograph) for swicthing and storing chromatographic eluates and moving them to the probe detection cell
- Used extensivley in our research involving signal enhancement by sample preconcentration.
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