Raftery Group, Purdue University Purdue University

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Metabolomics
NMR data analysis of biological specimens using 500 MHz (cryoprobe) system.
LCQ Mass spectrometer lab dedicated to metabolomics applications.

The emerging area of metabolomics describes the simultaneous detection and quantitative measurement of a large number of metabolites in biological samples such as normal and pathological tissue and bio-fluids. Detection of multiple metabolites, which are the end products of a multitude of genomic and proteomic functions promise immense applications in early diagnosis, prognosis and molecular level understanding of metabolic pathways associated with many diseases. Our laboratory extensively utilizes the latest technological advancements in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) methods for analyzing biological samples from a variety of pathological and other biological conditions. The complex datasets obtained are analyzed using multivariate statistical analyses. In addition, our lab is involved in the development of new chemical and technical methods for the enhancement of sensitivity and selectivity for biomarker detection.


[More on Metabolomics ]

Computation lab: Multivariate analysis of NMR and MS data.
Chemistry lab: Development of chemical methods for metabolomics applications