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Biochemistry Division Publications (2017-18)

Chittaranjan Das

  1. Puvar K, Zhou Y, Qiu J, Luo ZQ, Wirth MJ, Das C. (2017) Ubiquitin Chains Modified by the Bacterial Ligase SdeA Are Protected from Deubiquitinase Hydrolysis. Biochemistry. 56(36),4762-4766.
    PubMed Article Link

  2. Qiu J, Yu K, Fei X, Liu Y, Nakayasu ES, Piehowski PD, Shaw JB, Puvar K, Das C, Liu X, Luo ZQ. (2017) A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination. Cell Res. 27(7), 865-881.
    PubMed Article Link

  3. Scarborough NM, Godaliyadda GM, Ye DH, Kissick DJ, Zhang S, Newman JA, Sheedlo MJ, Chowdhury AU, Fischetti RF, Das C, Buzzard GT, Bouman CA, Simpson GJ. (2017) Dynamic X-ray diffraction sampling for protein crystal positioning. J Synchrotron Radiat. 24(Pt 1), 188-195.
    PubMed Article Link

 

Christine Hrycyna

  1. Namanja-Magliano HA, Bohn K, Agrawal N, Willoughby ME, Hrycyna CA, Chmielewski J. (2017) Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine. Bioorg Med Chem. 25(19),5128-5132.
    PubMed Article Link

  2. Bohn K, Lange A, Chmielewski J, Hrycyna CA. (2017) Dual Modulation of Human P-Glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood-Brain Barrier. Molec Pharmaceutics. 14(4),1107-1119.
    PubMed Article Link

  3. Diaz-Rodriguez V, Hsu E-T, Ganusova E, Werst E, Becker J, Hrycyna CA, Distefano M. (2017) α–Factor Analogues Containing Alkyne- and Azide Functionalized Isoprenoids are Efficiently Enzymatically Processed and Retain Wild Type Bioactivity. Bioconjugate Chem., in press.

 

Wen Jiang

  1. In vivo production of RNA nanostructures via programmed folding of single-stranded RNAs. Li M, Zheng M, Wu S, Tian C, Liu D, Weizmann Y, Jiang W, Wang G, Mao C. Nature communications. 2018; 9(1):2196. PubMed [journal]PMID: 29875441 PMCID: PMC5989258

  2. Cryo-EM structure of Escherichia coli σ70 RNA polymerase and promoter DNA complex revealed a role of σ non-conserved region during the open complex formation. Narayanan A, Vago FS, Li K, Qayyum MZ, Yernool D, Jiang W, Murakami KS. The Journal of biological chemistry. 2018; 293(19):7367-7375. PubMed [journal]PMID: 29581236 PMCID: PMC5949986

  3. States of phage T3/T7 capsids: buoyant density centrifugation and cryo-EM. Serwer P, Wright ET, Demeler B, Jiang W. Biophysical reviews. 2018; 10(2):583-596. PubMed [journal]PMID: 29243090 PMCID: PMC5899731

  4. Structure of the Marine Siphovirus TW1: Evolution of Capsid-Stabilizing Proteins and Tail Spikes. Wang Z, Hardies SC, Fokine A, Klose T, Jiang W, Cho BC, Rossmann MG. Structure (London, England : 1993). 2018; 26(2):238-248.e3. PubMed [journal]PMID: 29290487

  5. A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles. Chen J, Zhang C, Zhou Y, Zhang X, Shen C, Ye X, Jiang W, Huang Z, Cong Y. Journal of virology. 2018; 92(2). PubMed [journal]PMID: 29093091 PMCID: PMC5752931

  6. Defocus and magnification dependent variation of TEM image astigmatism. Yan R, Li K, Jiang W. Scientific reports. 2018; 8(1):344. PubMed [journal]PMID: 29321616 PMCID: PMC5762780

  7. Stability of Cucumber Necrosis Virus at the Quasi-6-Fold Axis Affects Zoospore Transmission. Sherman MB, Kakani K, Rochon D, Jiang W, Voss NR, Smith TJ. Journal of virology. 2017; 91(19). PubMed [journal]PMID: 28724762 PMCID: PMC5599764

  8. Atomic cryo-EM structures of viruses. Jiang W, Tang L. Current opinion in structural biology. 2017; 46:122-129. NIHMSID: NIHMS896279 PubMed [journal]PMID: 28787658 PMCID: PMC5683926

  9. Cryo-EM structure of the bacteriophage T4 isometric head at 3.3-Å resolution and its relevance to the assembly of icosahedral viruses. Chen Z, Sun L, Zhang Z, Fokine A, Padilla-Sanchez V, Hanein D, Jiang W, Rossmann MG, Rao VB. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(39):E8184-E8193. PubMed [journal]PMID: 28893988 PMCID: PMC5625921

  10. Adenoviral E4 34K protein interacts with virus packaging components and may serve as the putative portal. Ahi YS, Hassan AO, Vemula SV, Li K, Jiang W, Zhang GJ, Mittal SK. Scientific reports. 2017; 7(1):7582. PubMed [journal]PMID: 28790440 PMCID: PMC5548797

  11. Antibody-induced uncoating of human rhinovirus B14. Dong Y, Liu Y, Jiang W, Smith TJ, Xu Z, Rossmann MG. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(30):8017-8022. PubMed [journal]PMID: 28696310 PMCID: PMC5544331

  12. Structure of a headful DNA-packaging bacterial virus at 2.9 Å resolution by electron cryo-microscopy. Zhao H, Li K, Lynn AY, Aron KE, Yu G, Jiang W, Tang L. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(14):3601-3606. PubMed [journal]PMID: 28320961 PMCID: PMC5389284

  13. Binary self-assembly of highly symmetric DNA nanocages via sticky-end engineering Wu X, Wu C, Ding F, Tian C, Jiang W, Mao C, Zhang C. Chinese Chemical Letters. 2017 April; 28(4):851-856. My Bibliography [journal]

  14. Accurate model annotation of a near-atomic resolution cryo-EM map. Hryc CF, Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(12):3103-3108. PubMed [journal]PMID: 28270620 PMCID: PMC5373346

  15. A human antibody against Zika virus crosslinks the E protein to prevent infection. Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE Jr, Kuhn RJ, Rossmann MG. Nature communications. 2017; 8:14722. PubMed [journal]PMID: 28300075 PMCID: PMC5356071

  16. Real-time detection and single-pass minimization of TEM objective lens astigmatism. Yan R, Li K, Jiang W. Journal of structural biology. 2017; 197(3):210-219. NIHMSID: NIHMS830576 PubMed [journal]PMID: 27838367 PMCID: PMC5360486

  17. Structure of the immature Zika virus at 9 Å resolution. Prasad VM, Miller AS, Klose T, Sirohi D, Buda G, Jiang W, Kuhn RJ, Rossmann MG. Nature structural & molecular biology. 2017; 24(2):184-186. NIHMSID: NIHMS835123 PubMed [journal]PMID: 28067914 PMCID: PMC5296287

 

Philip Low

  1. Chen Q, Meng X, McQuade P, Rubins D, Lin SA, Zeng Z, Haley H, Miller P, González Trotter D, Low PS. (2017) Folate-PEG-NOTA-Al18F: A New Folate Based Radiotracer for PET Imaging of Folate Receptor-Positive Tumors. Mol Pharm. [Epub ahead of print]
    PubMed Article Link

  2. Poh S, Chelvam V, Kelderhouse LE, Ayala-López W, Vaitilingam B, Putt KS, Low PS. (2017) Folate-conjugated liposomes target and deliver therapeutics to immune cells in a rat model of rheumatoid arthritis. Nanomedicine (Lond). 12(20), 2441-2451.
    PubMed Article Link

  3. Kanduluru AK, Low PS. (2017)  Development of a Ligand-Targeted Therapeutic Agent for Neurokinin-1 Receptor Expressing Cancers.  Mol Pharm. 14(11), 3859-3865.
    PubMed Article Link

  4. Mahalingam SM, Dudkin VY, Goldberg S, Klein D, Yi F, Singhal S, O'Neil KT, Low PS. (2017) Bioconjug Chem. Evaluation of a Centyrin-Based Near-Infrared Probe for Fluorescence-Guided Surgery of Epidermal Growth Factor Receptor Positive Tumors. Epub Oct 17.
    PubMed Article Link

  5. Srinivasarao M, Low PS. (2017) Ligand-Targeted Drug Delivery. Chem Rev. 117(19), 12133-12164.
     PubMed Article Link

  6. Poh S, Putt KS, Low PS. (2017) Folate-Targeted Dendrimers Selectively Accumulate at Sites of Inflammation in Mouse Models of Ulcerative Colitis and Atherosclerosis. Biomacromolecules. 18(10), 3082-3088.
    PubMed Article Link

  7. Lee JYK, Cho SS, Zeh R, Pierce JT, Martinez-Lage M, Adappa ND, Palmer JN, Newman JG, Learned KO, White C, Kharlip J, Snyder P, Low PS, Singhal S, Grady MS. (2017)  Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging. J Neurosurg. 25, 1-14.
    PubMed Article Link

  8. Orellana EA, Tenneti S, Rangasamy L, Lyle LT, Low PS, Kasinski AL.  (2017) FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer. Sci Transl Med. 2, 9(401).
    PubMed Article Link

  9. Merzel RL, Frey C, Chen J, Garn R, van Dongen M, Dougherty CA, Kandaluru AK, Low PS, Marsh ENG, Banaszak Holl MM. (2017) Conjugation Dependent Interaction of Folic Acid with Folate Binding Protein. Bioconjug Chem. 28(9), 2350-2360.
    PubMed Article Link

  10. Pantaleo A, Kesely KR, Pau MC, Tsamesidis I, Schwarzer E, Skorokhod OA, Chien HD, Ponzi M, Bertuccini L, Low PS, Turrini FM. (2017) Syk inhibitors interfere with erythrocyte membrane modification during P falciparum growth and suppress parasite egress. Blood. 130(8), 1031-1040.
    PubMed Article Link

  11. Chandrupatla DMSH, Jansen G, Vos R, Verlaan M, Chen Q, Low PS, Windhorst AD, Lammertsma AA, van der Laken CJ, Molthoff CFM. (2017) In-vivo monitoring of anti-folate therapy in arthritic rats using [18F]fluoro-PEG-folate and positron emission tomography. Arthritis Res Ther. 19(1), 114.
    PubMed Article Link

 

Angeline Lyon

  1. Ben-Salem S, Robbins SM, Lm Sobreira N, Lyon A, Al-Shamsi AM, Islam BK, Akawi NA, John A, Thachillath P, Al Hamed S, Valle D, Ali BR, Al-Gazali L. (2017) Defect in phosphoinositide signalling through a homozygous variant in PLCB3 causes a new form of spondylometaphyseal dysplasia with corneal dystrophy. J Med Genet 104827.
    PubMed Article Link

  2. Hudson BN, Hyun SH, Thompson DH, Lyon AM. Biochemistry. (2017)  Phospholipase Cβ3 Membrane Adsorption and Activation Are Regulated by Its C-Terminal Domains and Phosphatidylinositol 4,5-Bisphosphate.  Biochemistry. 56(41), 5604-5614.
    PubMed Article Link

  3. Madukwe JC, Garland-Kuntz EE, Lyon AM, Smrcka AV. (2018) G protein βγ subunits directly interact with and activate phospholipase Cϵ. J Biol Chem. 2018 Apr 27;293(17):6387-6397. doi: 10.1074/jbc.RA118.002354. Epub 2018 Mar 13.
    PubMed Article Link

 

Andrew Mesecar

  1. Abuhammad A, Al-Aqtash RA, Anson BJ, Mesecar AD, Taha MO. (2017) Computational modeling of the bat HKU4 coronavirus 3CLpro inhibitors as a tool for the development of antivirals against the emerging Middle East respiratory syndrome (MERS) coronavirus. J Mol Recognit. 30(11).
    PubMed Article Link

  2. Daczkowski CM, Dzimianski JV, Clasman JR, Goodwin O, Mesecar AD, Pegan SD. (2017) Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species. J Mol Biol. 429(11), 1661-1683.
    PubMed Article Link

  3. Ghosh AK, Brindisi M, Yen YC, Cárdenas EL, Ella-Menye JR, Kumaragurubaran N, Huang X, Tang J, Mesecar AD. (2017) Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1'-P2' ligands. Bioorg Med Chem Lett. 27(11), 2432-2438.
    PubMed Article Link

  4. Clasman JR, Báez-Santos YM, Mettelman RC, O'Brien A, Baker SC, Mesecar AD. (2017) X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design. Sci Rep. 7, 40292.
    PubMed Article Link

 

Kavita Shah

  1. Nikhil K, Viccaro K, Shah K*. (2018) Multifaceted Regulation of ALDH1A1 by Cdk5 in Alzheimer's Disease Pathogenesis. Mol Neurobiol https://link.springer.com/article/10.1007/s12035-018-1114-9.

  2. Pollan SG, Huang F, Sperger JM, Lang JM, Morrissey C, Cress AE, Chu CY, Bhowmick NA, You S, Freeman MR, Spassov DS, Moasser MM, Carter WG, Satapathy SR, Shah K, Knudsen BS. (2018) Regulation of inside-out β1-integrin activation by CDCP1. Oncogene 37(21), 2817-2836. doi: 10.1038/s41388-018-0142-2.

  3. Reddy POV, Hridhay M, Nikhil K, Khan S, Jha PN, Shah K*, Kumar D (2018) Synthesis and investigations into the anticancer and antibacterial activity studies of β-carboline chalcones and their bromide salts. Bioorganic & Medicinal Chemistry Letters 28(8), 1278-1282. doi: 10.1016/j.bmcl.2018.03.033.

  4. Shah K*, Rossie S. (2018) Tale of the Good and Bad Cdk5: Remodeling of the Actin Cytoskeleton in the Brain. Mol Neurobiol 55(4), 3426-3438. doi: 10.1007/s12035-017-0525-3.

  5. Nikhil K, Shah K*. (2017) Cdk5-Mcl-1 Axis Promotes Mitochondrial Dysfunction and Neurodegeneration in Alzheimer Disease Model. J Cell Sci 130(18), 3023-3039.

  6. Rajasekhar K, Narayanaswamy N, Murugan NA, Viccaro K, Lee HG, Shah K, Govindaraju T. (2017) Aβ Plaque-Selective NIR Fluorescence Probe to Differentiate Alzheimer's Disease from Tauopathies. Biosensors and Bioelectronics. 98, 54-61. doi: 10.1016/j.bios.2017.06.030.

  7. Wang J, Nikhil K, Viccaro K, Lei C, White J, Shah K*.(2017) Phosphorylation-dependent Regulation of ALDH1A1 by Aurora Kinase A: Insights on their Synergistic Relationship in Pancreatic Cancer. BMC Biology, 15, 10. doi: 10.1186/s12915-016-0335-5.

  8. Wang J, Nikhil K, Viccaro K, Lei C, Jacobsen M, Sandusky G, Shah K*. (2017) Aurora A-Twist1 Axis Promotes Highly Aggressive Phenotypes in Pancreatic Carcinoma. J Cell Sci. 130(6), 1078-1093. doi: 10.1242/jcs.196790.

  9. Shah K*, Lahiri DK. (2017) A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5. Mol Neurobiol. 54(3), 2255-2268. doi:10.1007/s12035-016-9792-7.

  10. Reddy V, Mishra S, Tantak MP, Nikhil K, Sadana R, Shah K* and Kumar D. (2017) Design, synthesis and in vitro cytotoxicity studies of novel β-carbolinium bromides. Bioorg Med Chem Lett. 27(6), 1379-1384. doi: 10.1016/j.bmcl.2017.02.010.

 

Nikolai Skrynnikov

  1. Kurauskas V, Izmailov SA, Rogacheva ON, Hessel A, Ayala I, Woodhouse J, Shilova A, Xue Y, Yuwen T, Coquelle N, Colletier JP, Skrynnikov NR*, Schanda P* (2017) Slow conformational exchange and overall rocking motion in ubiquitin protein crystals. Nat Commun 8 (1),145.
    PubMed Article Link

  2. Rabdano SO, Izmailov SA, Luzik DA, Groves A, Podkorytov IS, Skrynnikov NR* (2017) Onset of disorder and protein aggregation due to oxidation-induced intermolecular disulfide bonds: case study of RRM2 domain from TDP-43. Sci Rep 7(1),11161.
    PubMed Article Link

  3. Izmailov SA, Podkorytov IS, Skrynnikov NR* (2017) Simple MD-based model for oxidative folding of peptides and proteins. Sci Rep 7(1), 9293.
    PubMed Article Link

  4. Tyuryaeva II, Lyublinskaya OG, Podkorytov IS, Skrynnikov NR* (2017) Origin of anti-tumor activity of the cysteine-containing GO peptides and further optimization of their cytotoxic properties. Sci Rep 7, 40217.
    PubMed Article Link

  5. Case DA, Skrynnikov NR* (2017) Interview with David A. Case: on force fields, biomolecular modeling, and NMR. Concepts Magn. Reson. A. In press.

  6. Rogacheva ON, Izmailov SA, Slipchenko LV, Skrynnikov NR* (2017) A new structural arrangement in proteins involving lysine NH3+ group and carbonyl. Sci Rep In press.

  7. Kämpf K, Rabdano SO, Izmailov SA, Groves A, Podkorytov IS, Skrynnikov NR. (2017) Local and global dynamics of intrinsically disordered proteins: a case study of H4 histone tail. FEBS J. In press.

  8. Rogacheva ON, Izmailov SA, Slipchenko LV, Skrynnikov NR.  (2017) New linear interaction between charged lysine side chain and carbonyl group in protein structures. FEBS J., 284, S1, 311.

  9. Luzik DA, Rabdano SO, Skrynnikov NR.  (2017) Non-native disulfide bridges in protein-peptide complex and in protein homodimers trigger unfolding and aggregation. FEBS J., 284, S1, 212.

  10. Podkorytov IS, Belousov MV, Bondarev SA, Kämpf K, Zhouravleva GA, Dvinskikh SV, Skrynnikov NR.  (2017)  Detection of flexible portion of protein chain in Sup35NM amyloid fibrils by means of diffusion-filtered NMR experiment.

 

Zhong-Yin Zhang

  1. Zhang, Z.-Y. (2017) Drugging the undruggable: therapeutic potential of targeting protein tyrosine phosphatases. Acc. Chem. Res. 50 (1), 122-129.
    PubMed Article Link

  2. Kobayashi, M., Bai, Y., Chen, S., Gao, R., Yao, C., Cai, W., Cardoso, A. A., Croop, J., Zhang, Z.-Y., and Liu, Y.  (2017)  Phosphatase PRL2 promotes oncogenic Notch1-induced T cell leukemia. Leukemia 31(3), 751-754.
    PubMed Article Link

  3. Yu, T., Zuo, Y., Cai, R., Huang, X., Wu, S., Zhang, C., Chin, Y. E., Li. D., Zhang Z., Xia, N., Wang Q., Shen, H., Yao, X., Zhang, Z.-Y., Xue, S., Shen, L., and Cheng, J.  (2017) SENP1 regulates IFN-g-STAT1 signaling through STAT3-SOCS3 negative feedback loop. Journal of Molecular Cell Biology 9(2), 44-153.
    PubMed Article Link

  4. Kobayashi, M., Nabinger, S., Bai, Y., Yoshimoto, M., Gao, R., Chen, S., Yao, C., Dong, Y., Zhang, L., Rodriguez, S., Yashiro-Ohtani, Y., Pear, W. S., Carlesso, N., Yoder, M. C., Kapur, R., Kaplan, M. H., Lacorazza, H. D., Zhang, Z.-Y., and Liu, Y. (2017) Protein tyrosine phosphatase PRL2 mediates Notch and Kit signals in early T cell progenitors, Stem Cells 35(4),1053-1064.
    PubMed Article Link

  5. Kobayashi, M., Chen, S., Bai, Y., Yao, C., Gao, R., Sun, X.-J., Mu, C., Twiggs, T., Yu, Z. H., Boswell, H. S., Yoder, M. C., Kapur, R., Mulloy, J. C., Zhang, Z.-Y., and Liu, Y. (2017) Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia. Leukemia 31(6),1453-1457.
    PubMed Article Link

  6. Ruddraraju, K. V. and Zhang, Z.-Y. (2017) Covalent inhibition of protein tyrosine phosphatases. Molecular BioSystems 13(7), 1257-1279.
    PubMed Article Link

  7. Prabhu, L., Wei, H., Chen, L., Demir, Ö., Sandusky, G., Sun, E., Wang, J., Mo, J., Zeng, L., Fishel, M., Safa, A., Amaro, R., Korc, M., Zhang, Z.-Y., and Lu, T. (2017) Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.  Oncotarget8(25), 39963-3997.
    PubMed Article Link

  8. Heckman, C. A., Pandey, P., Cayer, M. L., Biswas, T., Zhang, Z.-Y., and Boudreau, N. S. (2017) The Tumor Promoter-Activated Protein Kinase Cs are a System for Regulating Filopodia.  Cytoskeleton 74(8):297-314.
    PubMed Article Link

  9. Sacchetti, C., Bai, Y., Stanford, S. M., Di Bebedetto, P., Cipriani, P., Santelli, E., Piera-Velazquez, S., Chernitskiy, V., Kiosses, W. B., Ceponis, A., Kaestner, K., Boin, F., Jimenez, S. A., Giacomelli, R., Zhang, Z.-Y., and Bottini, N. (2017) PTP4A1 promotes TGFb signaling and fibrosis in systemic sclerosis. Nat Comm 8, 1060.
    PubMed Article Link

  10. Yamashita, N., Joshi, R., Zhang, S., Zhang, Z.-Y., and Kuruvilla, R. (2017) Phospho-regulation of soma-to-axon transcytosis of neurotrophin receptors. Dev. Cell 42(6), 626-639.
    PubMed Article Link

  11. Frankson, R., Yu, Z.-H., Bai, Y., Li, Q., Zhang, R.-Y., Zhang, Z.-Y. (2017) Therapeutic targeting of oncogenic tyrosine phosphatases. Cancer Research 77(21):5701-5705.
    PubMed Article Link

  12. Prabhu, L., Chen, L., Wei, H., Safa, A., Zhang, Z.-Y., and Lu, T. “Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases”, Molecular BioSystems 13, 2509-2520 (2017).

  13. Yu, Z.-H., and Zhang, Z.-Y. “Regulatory mechanisms and novel therapeutic targeting strategies for protein tyrosine phosphatases” Chemical Reviews 118, 1069-1091 (2018).

  14. McQueeney, K. E., Salamoun, J. M., Burnett, J. C., Barabutis, N., Pekic, P., Lewandowski, S. L., Llaneza, D. C., Cornelison, R., Bai, Y., Zhang, Z.-Y., Catravas, J. D., Landen, Jr, C. N., Wipf, P., Lazo, J. S., and Sharlow, E. R. “Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor”, Oncotarget 9, 8223-8240 (2018).

  15. Hsu, A. Y., Gurol, T., Sobreira, T. J., Zhang, S., Moore, N., Cai, C., Zhang, Z.-Y., and Deng, Q. “Development and characterization of an endotoxemia model in zebra fish”, Frontiers in Immunology 9, 607 (2018).

  16. Zehender, A., Huang, J., Györfi, A.-H., Matei, A.-E., Trinh-Minh, T., Xu, X., Li, Y.-N., Chen, C.-W., Lin, J., Dees, C., Beyer, C., Gelse, K., Zhang, Z.-Y., Bergmann, C., Ramming, A., Birchmeier, W., Distler, O., Schett, G., Distler, J. H. W. “The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis”, Nature Communications 9, in press (2018).

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