- Associate Professor of Practice — Biochemistry
- Office: WTHR 155
- For Professor Stefan Paula's individual Home Page click here.
His research interests are in the area of computer-assisted drug design. His group uses a combination of experimental and computational methodologies to gain an understanding of how small bioactive molecules interact with their protein receptors. The ultimate goal is the design of novel molecules with improved bioactivities. Several enzyme/inhibitor systems are currently under study, including inhibitors of the sarco/endoplasmic reticulum calcium ATPase, the sodium/potassium ATPase, xanthine oxidase, aromatase, and histone deacetylase. The preferred approach entails a computational analysis of the interactions between a compound class and the receptor, followed by virtual screening of large compound libraries with predictive models and experimental testing of selected molecules in bioassays. To gain access to specific molecules, his research group collaborates with several synthetic organic chemists. Dr. Paula is a member of the American Chemical Society, the Biophysical Society, and the Council on Undergraduate Research.
- Postdoctoral Fellow, 1998 - 1999, Max-Planck-Institute of Biochemistry, Munich, Germany
- Ph.D., 1998, University of California at Santa Cruz
- M.Sc., 1992, University of Kaiserslautern, Germany
- Invited Keynote Speaker, International Conference on Advances in Bioscience and Bioengineering, Sydney, Australia, 2014
- Professional Development Award, College of Arts & Sciences, NKU, 2013
- Faculty Excellence Award for Sustained Excellence in Scholarly or Creative Activity, NKU, 2013
- Postdoctoral Fellowship of the Max-Planck-Society, 1998 - 1999
- UC Santa Cruz Graduate Fellowship, 1995 - 1996
- Fulbright Fellowship, 1992 - 1993