Publications

UG = Undergraduate Student 

82. Clark, M. G.; Gonzalez, G.; Luo, Y.; Aldana-Mendoza, J.; Carlsen, M. S.; Eakins, G.; Dai, M.; Zhang, C.* "Real-Time Precision Opto-Control of Chemical Processes in Live Cells" Nature Communications, 2022, accepted.

 

81. de Andrade Horn, P.; Sims, H. S. Dai, M.* "Nickel-Catalyzed Tandem Ueno-Stork Cyclization: Stereoselective 1,2-Dicarbofunctionalization of Cyclic Alkenes" J. Org. Chem. 2022, 87, 8796-8801.

 

80. Peery, R.; Cui, Q.; Kyei-Baffour, K.; Josephraj, S.; Huang, C.; Dong, Z.; Dai, M.;* Zhang, J.-T.* Liu, J.-Y.;* “A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells” Bioorg. Med. Chem. 2022, 65, 116761.

 

79. Luo, Y.; Li, L.; Dai, M.* “Complex Natural Products Total Syntheses Facilitated by Palladium-Catalyzed Carbonylative Cyclizations” Chapter 18 for “The Chemical Transformations of C1 Compounds”, Volume 2, 793-826, Book Editors: Kuling Ding, Xiao-Feng Wu, Buxing Han, Zhongmin Liu, Wiley.

 

78. Sims, H. S.; de Andrade Horn, P.; Isshiki, R.; Lim, M. (UG); Xu, Y.; Grubbs, R. H.; Dai, M* "Catalysis-Enabled Concise and Stereoselective Total Synthesis of the Tricyclic Prostaglandin D₂ Metabolite Methyl Ester" Angew. Chem. Int. Ed., 2022, 61, e202115633.

 

77. Jiang, B.; Dai, M.* “11-Step and Scalable Total Synthesis of Hamigeran M Enabled by Five C-H Functionalizations" J. Am. Chem. Soc. 2021, 143, 20084-20089. 

 

76. Ma, D.;^ Martin, B. S.;^ Gallagher S. K. (UG); Saito, T. (UG); Dai, M.* “One-Carbon Insertion and Polarity Inversion Enabled a Pyrrole Strategy to the Total Syntheses of Pyridine-Containing Lycopodium Alkaloids: Complanadine A and Lycodine” J. Am. Chem. Soc. 2021, 143, 16383-16387. (^These authors contributed equally.)

i) Highlighted by X-MOL.

 

75. Wang, Y.-C.;^ Cui, C.;^ Dai, M.* "Flow Chemistry-Enabled Divergent and Enantioselective Total Syntheses of Massarinolin A, Purpurolides B, D, E, 2,3-Deoxypurpurolide C, and Structural Revision of Massarinolin A" Angew. Chem. Int. Ed. 2021, 60, 24828-24832. (Selected as a Hot Paper; ^These authors contributed equally.)

 

i) Featured as an Inside Cover.

ii) Highlighted by WileyChem.

 

74. Negi, V.; Yang, J.; Speyer, G.; Pulgarin, A.; Handen, A.; Zhao, J.; Tai, Y. Y.; Tang, Y.; Culley, M. K.; Yu, Q.; Forsythe, P.; Gorelova, A.; Watson, A. M.; Aaraj, Y. A.; Satoh, T.; Sharifi-Sanjani, M.; Rajaratnam, A.; Sembrat, J.; Provencher, S.; Yin, X.; Vargas, S. O.; Rojas, M.; Bonnet, S.; Torrino, S.; Wagner, B. K.; Schreiber, S. L.; Dai, M.; Bertero, T.; Ghouleh, I. A.; Kim, S.; Chan, S. Y.* “Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension” Science Advances, 2021, 7:eabh3794.

 

73. Pal, R.; Dai, M.; Seleem, M. N.* “High-throughput screening identifies a novel natural product-inspired molecule inhibiting Clostridioides difficile in vitro and in vivo” Sci. Rep. 2021, 11, 10913.

 

72. Cui, C.;^ Dwyer, B. G.;^ Liu, C.; Abegg, D.; Cai, Z.; Hoch, D.; Yin, X.; Qiu, N.; Liu, J.; Adibekian, A.;* Dai, M.* "Total Synthesis and Target Identification of the Curcusone Diterpenes " J. Am. Chem. Soc. 2021, 143, 4379. (^These authors contributed equally.)

i) Preprint: ChemRxiv 2020.

ii) Highlighted by X-MOL.

iii) Featured in Purdue News, ScienceDaily, NSF Research News, and over thirty other news/websites in different languages.

iv) Highlighted in Synfacts.

 

71. Raffa, N.; Won, T. H.; Sukowaty A.; Candor, K.; Cui, C.; Halder, S.; Dai, M.; Figueroa, J. A. L.; Schroeder, F. C.; Keller, N. P.* "Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity" Proc. Natl. Acad. Sci. USA, 2021, 118, e2015224118. 

 

70. Liang, W.; Cai, X.; Dai, M.* "Cu-Catalyzed Hydroxycyclopropanol Ring-Opening Cyclization to Tetrahydrofurans and Tetrahydropyrans: Short Total Syntheses of Hyperiones" Chem. Sci. 2021, 12, 1311.

i) Highlighted by X-MOL

 

69. Cai, X.; Liang, W.; Liu, M. (UG); Li, X. (UG); Dai, M.* "Catalytic Hydroxycyclopropanol Ring-Opening Carbonylative Lactonization to Fused Bicyclic Lactones" J. Am. Chem. Soc. 2020, 142, 13677-13682.

i) Highlighted by X-MOL

ii) Highlighted in Synfacts. 

 

68. Kyei-Baffour, K.; Davis, D. C.; Boskovic, Z.; Kato, N.;* Dai, M.* "Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug resistant parasites" Bioorg. Med. Chem. 2020, 28, article 115678. 

 

67. Yin, X.; Ma, K.; Dong, Y. (UG); Dai, M.* "Pyrrole Strategy to the γ-Lactam-Containing Stemona Alkaloids: (±)-Stemoamide, (±)-Tuberostemoamide, and (±)-Sessilifoliamide A" Org. Lett. 2020, 22, 5001-5004. 

 

66. Peery, R.; Kyei-Baffour, K.; Dong, Z.; de Andrade Horn, P.; Dai, M.;* Liu, J.;* Zhang, J.* “Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation” J. Med. Chem. 2020, 63, 7243-7251.

 

65. Jiang, B.; Dai, M.* “Synthetic Studies towards the Hamigerans with a 6-7-5 Tricyclic Core” Org. Lett. 2020, 22, 4176-4179.

 

64. Huang, L.; Li, X.; Zhang, W.; Ung, N.; Liu, N.; Yin, X.; Li, Y.; Mcewan, R. E.; Dilkes, B.; Dai, M.; Hicks, G. R.; Raikhel, N. V.; Staiger, C. J. Zhang, C.* “Endosidin20 Targets the Cellulose Synthase Catalytic Domain to Inhibitor Cellulose Biosynthesis” Plant Cell, 2020, 32, 2141-2157 (accepted as a breakthrough report).

 

63. Oleson, A.; Zhu, T.; Dunn, I.; Bialas, D.; Bai, Y.; Zhang, W.; Dai, M.; Reichman, D.; Tempelaar, R.; Huang, L.; Spano, F.* “Perylene Diimide- Based Hj- and hJ-Aggregates: The Prospect of Exciton Band Shape Engineering in Organic Materials” J. Phys. Chem. C 2019, 123, 20567-20578.

 

62. Huang, L.; Li, X.; Li, Y.; Yin, X.; Li, Y.; Wu, B.; Mo, H.; Liao, C.; Mengiste, T.; Guo, W.; Dai, M.; Zhang, C.* “Endosidin2-14 targets the exocyst complex in plants and fungal pathogens to inhibit exocytosis” Plant Physiology 2019,180, 1756-1770.

 

61.Mohammad, H.^; Kyei-Baffour, K.^; Abutaleb, N. S.; Dai, M.*; Seleem, M.* "An aryl isonitrile compound with an improved physicochemical profile that is effective in two mouse models of multidrug-resistant Staphylococcus aureus infection" J. Glob. Antimicrob. Resist. 2019, 1-7 (doi:10.1016/j.jgar.2019.04.016). (^These authors contributed equally.)

 

 

60. Kyei-Baffour, K.^; Mohammad, H.^; Seleem, M.*; Dai, M.* "Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus" Bioorg. Med. Chem. 2019, 27, 1845-1854. (^These authors contributed equally.)

 

59. Luo, Y.; Yin, X.; Dai, M.* "Total Synthesis of trans-Resorcylide via Macrocyclic Stille Carbonylation" J. Antibiotics 2019, 72, 482-485. (Special Issue dedicated to Professor Samuel J. Danishefsky)

 

58. Cai, X.; Liang, W.; Dai, M.* "Total Syntheses via Cyclopropanols" Tetrahedron 2019, 75, 193-208. (Invited Special Issue Paper: Recent Applications of Metal Catalysis in Natural Product Synthesis. Guest Editors: Jeremy May and John Wood)

 

57. Davis, D. C.^; Hoch, D. G.^; Wu, L.; Abegg, D.; Martin, B. S. Zhang, Z.-Y.*; Adibekian, A.*; Dai, M.* "Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids" J. Am. Chem. Soc. 2018, 140, 17465-17473. (^These authors contributed equally.)

i) Highlighted by Synfacts

ii) Highlighted in: Science Daily, January 17, 2019 and Purdue News, January 22, 2019.

 

56. Ma, K.^; Yin, X. L.^; Dai, M.* "Total Syntheses of Bisdehydroneostemoninine and Bisdehydrostemoninine by Catalytic Carbonylative Spirolactonization" Angew. Chem. Int. Ed. 2018, 57, 15209-15212. (^These authors contributed equally.)

i) Highlighted by Synfacts

 

55. Cai, X.; Bai, Y.; Dai, M.* "Total Syntheses of Spinosyn A" Synlett 2018, 2623-2632. (Invited Synlett Account contribution by Prof. Peter Vollhardt)

 

54. Ma, K.^; Martin, B. S.^; Yin, X. L.^; Dai, M.* "Natural Product Syntheses via Carbonylative Cyclizations" Nat. Prod. Rep. 2019, 36, 174-219 (^These authors contributed equally.)

i) Highlighted by X-MOL

 

53. Ye, Z.^; Cai, X.^; Li, J. (UG), Dai, M.* "Catalytic Cyclopropanol Ring Opening for Divergent Syntheses of gamma-Butyrolactones and delta-Ketoesters Containing All-Carbon Quaternary Centers" ACS Catalysis 2018, 8, 5907-5914. (^These authors contributed equally.)

i) Highlighted by X-MOL

 

52. Ye, Z.; Adhikari, S.; Xia, Y.*; Dai, M.* "Expedient Syntheses of N-Heterocycles via Intermolecular Amphoteric Diamination of Allenes" Nature Communications 2018, 9, 721.

i) Highlighted by Synfacts

ii) Highlighted by X-MOL

 

51. Li, Y.; Yin, X. L.; Dai, M.* "Catalytic Macrolactonizations for Natural Product Synthesis" Nat. Prod. Rep. 2017, 34, 1185-1192.

i) Featured as Front Cover

 

50. Li, Y.; Dai, M.* "Total Syntheses of the Reported Structures of Curcusone I and J through Tandem Gold Catalysis" Angew. Chem. Int. Ed. 2017, 56, 11624-11627

i) Highlighted by Synfacts

ii) Highlighted by X-MOL

 

49. Yin, X.; Mohammad, H.; Eldesouky, H. E.; Abdelkhalek, A.; Seleem, M. N.;* Dai, M.* "Rapid Syntheses of Bicyclic Lactones via Palladium-Catalyzed Aminocarbonylative Lactonizations" Chem. Commun. 2017, 53, 7238-7241 (Invited contribution to the ChemComm Emerging Investigators Issue 2017).

i) Highlighted by X-MOL

 

48. Mohammad, H.†; Kyei-Baffour, K.†; Younis, W.; Davis, D. C.; Eldesouky, H.; Seleem, M. N.;* Dai, M.* "Investigation of Aryl Isonitrile Compounds with Potent, Broad-spectrum Antifungal Activity" Bioorg. Med. Chem. 2017, 25, 2926-2931. (†Equal contribution; Invited contribution in honor of Professor Xiaoguang Lei’s Tetrahedron Young Investigator Award 2017).

 

47. Bai, Y.; Davis, D. C.; Dai, M.* "Natural Product Synthesis via Palladium-Catalyzed Carbonylation" J. Org. Chem., 2017, 82, 2319-2328 (Invited JOCSynopsis contribution by Professor Dale Poulter).

 

46. Brust, T. F.; Alongkronrusmee, D.; Soto-Velasquez, M.; Baldwin, T. A.; Ye, Z.; Dai, M.; Dessauer, C. W.; van Rijn, R. M.; Watts, V. J.* "Identification of a selective small molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties" Science Signaling, 2017, 10, eaah5381.

i) This work was highlighted by Science News Story.

 

45. Gettys, K. E.; Ye, Z.; Dai, M.* "Recent Advances in Piperazine Synthesis" Synthesis, 2017, 49, 2589-2604 (Invited review article by Professor Dieter Enders).

 

44. Davis, D. C.; Haskins, C. W.; Dai, M.* "Radical Cyclopropanol Ring Opening Initiated Tandem Cyclizations for Efficient Synthesis of Phenanthridines and Oxindoles" Synlett, 2017, 28, 913-918 (Invited contribution for the special issue dedicated to the EuCheMS Young Investigator Workshop 2016).

 

43. Li, Y.; Wei, M. (UG); Dai, M.* "Gold Catalysis-Facilitated Rapid Synthesis of the Daphnane/Tigliane Tricyclic Core" Tetrahedron, 2017, 73, 4172-4177 (Invited contribution the "New Advances in Pericyclic Reactions" Symposium-in-Print guest-edited by Prof. Uttam Tambar).

 

42. Dai, M.* “Harnessing Molecular Strain in Organic Synthesis and Related Fields” Curr. Org. Chem. 2016, 20, 1850-1850.

 

41. Bai, Y.; Shen, X. (UG); Li, Y.; Dai, M.* "Total Synthesis of Spinosyn A via Carbonylative Macrolactonization" J. Am. Chem. Soc. 2016, 138, 10838-10841.

i) Highlighted by Synfacts.

ii) Highlighted in the Today’s Topic of the Agricultural Chemical Society of Japan: 2017, Vol. 55, No. 8, 523-525.

 

40. Davis, D. C.; Walker, K. L.; Hu, C.; Zare, R. N.; Waymouth, R. M.*; Dai, M.* "Catalytic Carbonylative Spirolactonization of Hydroxycyclopropanols" J. Am. Chem. Soc. 2016, 138, 10693-10699.

i) Highlighted by Organic Chemistry Portal.

 

39. Ye, Z.; Gettys, K. E.; Dai, M.* "Opportunities and Challenges for Direct C-H Functionalization of Piperazines" Beilstein J. Org. Chem. 2016, 12, 702-715. (Invited for the Thematic Series "C-H Functionalization/Activation in Organic Synthesis"; Guest Editor: Prof. Richmond Sarpong)

 

38. Lin, Z.; Tan, L.; Yang Y.; Dai, M.; Tureček, F.*, Ouyang, Z.,* and Xia, Y.* "Gas-Phase Reactions of Cyclopropenylidene with Protonated Alkyl Amines" Analyst 2016, 2412-2417.

 

37. Ye, Z.; Gettys, K. E.; Shen, X. (UG); Dai, M.* "Copper-Catalyzed Cyclopropanol Ring Opening Csp3-Csp3 Cross Couplings with (Fluoro)Alkyl Halides" Org. Lett. 2015, 17, 6074-6077.

 

36. Chou, D. H.-C.; Vetere, A.; Choudhary, A.; Scully, S. S.; Schenone, M.; Tang, A.; Gomez, R.; Burns, S. M.; Lundh, M.; Vital, T.; Comer, E.; Faloon, P. W.; Dancik, V.; Ciario, C.; Paulk, J.; Dai, M.; Reddy, C.; Sun, H.; Young, M.; Donato, N.; Jaffe, J.; Clemons, P. A.; Palmer, M.; Carr, S. A.; Schreiber, S. L.; Wagner, B. K.* "Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling" J. Am. Chem. Soc. 2015, 137, 7929-7934.

 

35. Davis, D. C.^; Mohammad, H.^; Kyei-Baffour, K.; Younis, W.; Creemer, C. N. (UG); Seleem, M. N.*; Dai, M.* "Discovery and Characterization of Aryl Isonitriles as A New Class of Compounds versus Methicillin- and Vancomycin-resistant Staphylococcus aureus" Eur. J. Med. Chem. 2015, 101, 384-390. (^These authors contributed equally.)

 

34. Bai, Y.; Dai, M.* "Strategies and Methods for the Synthesis of Anti-Cancer Natural Product Neopeltolide and Its Analogs" Curr. Org. Chem. 2015, 19, 871-885. (Invited contribution)

 

33. Ye, Z.; Dai, M.* "An Umpolung Strategy for the Synthesis of beta-Aminoketones via Copper-Catalyzed Electrophilic Amination of Cyclopropanols" Org. Lett. 2015, 17, 2190-2193.

i) Highlighted by X-MOL.

 

32. Li, Y.^; Ye, Z.^; Bellman, T. M.; Chi, T. (UG); Dai, M.* "Efficient Synthesis of beta-CF3/SCF3-Substituted Carbonyls via Copper-Catalyzed Electrophilic Ring-Opening Cross-Coupling of Cyclopropanols" Org. Lett. 2015, 17, 2186-2189. (^These authors contributed equally.)

i) Highlighted by Synfacts.

ii) Highlighted by X-MOL.

 

31. Ye, Z.; Brust, T. F.; Watts, V. J.*; Dai, M.* "Palladium-Catalyzed Regio- and Stereoselective gamma-Arylation of Tertiary Allylic Amines: Identification of Potent Adenylyl Cyclase Inhibitors" Org. Lett. 2015, 17, 892-895.

 

30. Lee, H. J.^; Zhang, W.(UG)^; Zhang, D.; Yang, Y.; Liu, B.; Barker, E. L; Buhman, K. K.; Slipchenko, L. V.; Dai, M.*; Cheng, J.-X.* "Assessing Cholesterol Storage in Live Cells and C. elegans by SRS Imaging of Phenyl-Diyne Cholesterol" Sci. Rep. 2015, 5, 7930. doi:10.1038/srep07930. (^These authors contributed equally.)

 

29. Dai, M.* Bai, Y.; Dexter, D. C.; “Synthesis of tetrahydropyran- or tetrahydrofuran-containing macrolides by palladium-catalyzed alkoxycarbonylative macrolactonizations” Synthesis, 2014, 46, A120-A121 (Synform 2014/09).

 

28. Yang, Y.^; Bai, Y.^; Sun, S.(UG); Dai, M.* "Biosynthetically Inspired Divergent Approach to Monoterpene Indole Alkaloids: Total Synthesis of Mersicarpine, Leuconodines B and D, Leuconoxine, Melodinine E, Leuconolam, and Rhazinilam" Org. Lett. 2014, 16, 6216-6219. (^These authors contributed equally.)

i) Top 20 most read article in Organic Letters November 2014.

ii) The 2015 Organic Letters Outstanding Author of the Year Lectureship Award winning paper.

iii) Highlighed by Synfacts.

 

27. Zhang, W. (UG)^; Haskins, C. W.^; Yang, Y.; Dai, M.* "Synthesis of Nitriles via Palladium-Catalyzed Water Shuffling From Amides to Acetonitrile" Org. Biomol. Chem. 2014, 12, 9109-9112. (^These authors contributed equally.)

 

26. Yang, Y.; Dai, M.* "Total Synthesis of Lyconadins:Finding Efficiency and Diversity" Synlett 2014, 25, 2093-2098. (Invited contribution)

 

25. Bai, Y.; Davis, D. C.; Dai, M.* "Synthesis of tetrahydropyran/tetrahydrofuran-containing macrolides by palladium-catalyzed alkoxycarbonylative macrolactonization" Angew. Chem. Int. Ed. 2014, 53, 6519-6522 (selected as a Very Important Paper).

i) Featured in SYNFORM;

ii) Highlighted by Organic Chemistry Portal.

 

24. Yang, Y.; Haskins, C. W.; Zhang, W. (UG); Low, P. L. (UG); Dai, M.* "Divergent total syntheses of lyconadins A and C" Angew. Chem. Int. Ed. 2014, 53, 3922-3925.

i) Highlighted by Organic Chemistry Portal.

ii) Highlighted by Amphoteros.

 

Before Purdue

23. Boskovic, Z. V.; Hussain, M. M.; Adams, D. J.; Dai, M., Schreiber, S. L. "Synthesis of piperlogs and analysis of their effects on cells" Tetrahedron, 2013, 69, 7559-7567. (Special issue to honor Professor Paul Wender on his receipt of the 2012 Tetrahedron Prize for Creativity in Organic Chemistry)

22. Hartwell, K. A.; Miller, P. G.; Mukherjee, S.; Kahn, A. R.; Stewart, A. L.; Logan, D. J.; Negri, J. M.; Duvet, M.; Järås, M.; Puram, R.; Dancik, V.; Al-Shahrour, F.; Kindler, T.; Tothova, Z.; Chattopadhyay, S.; Hasaka, T.; Narayan, R.; Dai. M.; Huang, C.; Shterental, S.; Chu, L. P.; Haydu J. K.; Shieh, J. H.; Steensma, D. P.; Munoz, B.; Bittker, J.; Shamji, A. F.; Clemons, P.; Tolliday, N. J.; Carpenter, A. E.; Gilliland, D. G.; Stern, A. M.; Moore, M. A. S.; Scadden, D. T.; Schreiber, S. L.; Ebert, B. L.; Golub, T. R. "Niche-based screening identifies small-molecule inhibitors of leukemia stem cells" Nat. Chem. Bio., 2013, 9, 840-848.

21. Dai. M.*; Boskovic, Z. "Ruthenium complex of N,N’,N",-trimethyl-1,4,7-triazacyclononane and ruthenium complexes of cis-diaquabis (6,6’-dichloro-2,2’-bipyridine)", first update, Handbook of Reagents for Organic Synthesis: Catalytic Oxidation Reagents (Ed. Fuchs, P. L.), Wiley, 2013, 561-565.

20. Adams, D. J.^; Dai, M.^; Pellegrino, G.; Wagner, B. K.; Stern, A. M.; Shamji, A. F.; Schreiber, S. L. "Synthesis, Cellular Evaluation, and Mechanism of Action of Piperlongumine Analogs" Proc. Natl. Acad. Sci. USA, 2012, 109, 15115. (^These authors contributed equally.)

19. Peng, F.; Dai, M.; Angeles, A. R.; Danishefsky, S. J. "Permuting Diels-Alder and Robinson Annulation Stereopatterns" Chem. Sci. 2012, 3, 3076. (The 4th most-Accessed Article: August, 2012.)

18. Wang, Z.; Dai, M.; Park, P. K.; Danishefsky, S. J. "Synthetic studies toward (+)-cortistatin A" Tetrahedron, 2011, 67, 10249. (Special issue dedicated to Professor Gilbert Stork’s 90th birthday.)

17. Luo, T.; Dai, M.; Zheng, S-L.; Schreiber, S. L. "Synthesis of α-Pyrones by Gold-Catalyzed Coupling Reactions" Org. Lett. 2011, 13, 2834.

16. Hayden, A. E.; DeChancie, J.; George, A. H.; Dai, M.; Yu, M. L.; Danishefsky, S. J.; Houk, K. N "Origins of the Regioselectivities in the Diels−Alder Reactions of Vinylindenes with 1,4-Quinone Monoketal and Acrolein Dienophiles" J. Org. Chem. 2009, 74, 6770.

15. Dai, M.; Danishefsky, S. J. "An oxidative dearomatization cyclization model for cortistatin A" Heterocycles 2009, 77, 157. (Special issue dedicated to Dr. Keiichiro Fukumoto’s 75th birthday)

14. Dai, M.; Krauss, J. I.; Danishefsky, S. J. "Total synthesis of Spirotenuipesines A and B" J. Org. Chem. 2008, 73, 9576. (Special issue in the memory of Professor A. I. Meyers.)

13. Dai, M.; Wang, Z.; Danishefsky, S. J. "A novel α,β-unsaturated nitrone-aryne [3+2] cycloaddition and its application in the synthesis of the cortistatin core" Tetrahedron Lett. 2008, 49, 6613.

12. Dai, M.; Danishefsky, S. J. "A concise synthesis of the cortistatin core" Tetrahedron Lett. 2008, 49, 6610.

11. Lei, X. G.; Dai, M.; Hua, Z. H.; Danishefsky, S. J. "Biomimetic total synthesis of tricycloillicinone and mechanistic studies toward the rearrangement of prenyl phenyl ethers" Tetrahedron Lett. 2008, 49, 6383.

10. Li. Z. T.; Gao, Y. X.; Tang, Y. F.; Dai, M.; Wang G. X.; Wang, Z. D.; Yang, Z. "Total synthesis of crisamicin A" Org. Lett. 2008, 10, 3017.

9. Dai, M.; Danishefsky, S. J. "The total synthesis of spirotenuipesines A and B" J. Am. Chem. Soc. 2007, 129, 3498. (The 3rd most-Accessed Articles: January-March, 2007; the 6th most-Accessed Articles: 2007; Highlighted by JACS Virtual Issue "The Synthesis of Biologically Active Natural Products" J. Am. Chem. Soc. 2008, 130, 6654; Highlighted by Synfacts, 2007, 08, 0783.)

8. Dai, M.; Sarlah, D.; Yu, M. L.; Danishefsky, S. J.; Jones, G. J.; Houk, K. N. "Highly selective Diels-Alder reactions of directly connected enyne dienophiles" J. Am. Chem. Soc. 2007, 129, 645. (Highlighted by Organic Chemistry Portal ID: J48-Y2007-0160.)

7. Liu, Y. X.; Lu, K.; Dai, M.; Wang, K.; Wu, W. Q.; Chen, J. H.; Quan, J. M.; Yang, Z. "An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions" Org. Lett. 2007, 9, 805.

6. Tang, Y. F.; Zhang, Y. D.; Dai, M.; Luo, T. P.; Deng, L. J.; Chen, J. H.; Yang, Z. "A highly efficient synthesis of the FGH ring of micrandilactone A: Application of thioureas as ligands in the Co-catalyzed Pauson-Khand reaction and Pd-catalyzed carbonylative annulation" Org. Lett. 2005, 7, 885.

5. Liang, B.; Dai, M.; Chen. J. H.; Yang, Z. "Copper-free Sonogashira coupling reaction with PdCl2 in water under aerobic conditions" J. Org. Chem. 2005, 70, 391. (The 10th most-Accessed Articles: January-March, 2005; the 12th most-Accessed Articles: 2005; Highlighted by Organic Chemistry Portal ID: J42-Y2005-090.)

4. Xiong, Z.-C.; Wang, N.-D.; Dai, M.; Li, A.; Chen. J. H.; Yang, Z. "Synthesis of novel palladacycles and their application in the Heck and Suzuki reaction under aerobic conditions" Org. Lett. 2004, 6, 3337.

3. Dai, M.; Liang, B.; Wang, C. H.; You, Z. J.; Xiang, J.; Dong, G. B.; Chen. J. H.; Yang, Z. "A novel thiourea ligand applied in Heck, Suzuki and Suzuki carbonylative reactions" Adv. Synth. Catal. 2004, 346, 1669.

2. Dai, M.; Liang, B.; Wang, C. H.; Chen. J. H.; Yang, Z. "Synthesis of a novel C2-symmetric thiourea and its application in the Pd-catalyzed cross-coupling reactions with arenediazonium salts under aerobic conditions" Org. Lett. 2004, 6, 221.

1. Dai, M.; Wang, C. H.; Dong, G. B.; Xiang, J.; Luo, T. P.; Liang, B.; Chen. J. H.; Yang, Z. "Development of thiourea-based ligands for the palladium-catalyzed bis(methoxycarbonylation) of terminal olefins" Eur. J. Org. Chem. 2003, 4346.

Patents

 

7. “Aryl Isonitrile Compounds as A New Class of Potent, Broad-Spectrum Antifungal Compounds” Kyei-Baffour, K.; Seleem, M.; Dai, M.; Mohammad, H. T. U.S. Pat. Appl. Publ. US 2017/0181997 A1; June 29, 2017.
 
6. “New Methods for 1,4-Diazo N-Heterocycle Synthesis” Dai, M.; Ye, Z. U.S. Pat. Appl. Publ. US 2019/0055205 A1; February 21, 2019.
 
5. “Lactones” Dai, M.; Seleem, M.; Yin, X. United State Patent US 10,087,190 B1, October 2, 2018.
 
4. “Adenylyl Cyclase Inhibitors for Neuropathic and Inflammatory Pain” Dai, M.; Watts, V. J.; Ye, Z. United States Patent US 10,100,001 B2; October 16, 2018.
 
3. “Aryl Isonitriles as A New Class of Antimicrobial Compounds” Seleem, M.; Dai, M.; Davis, D. C.; Mohammad, H. T. United States Patent US 10,364,224 B2; July 30, 2019.
 
2. “Raman Tags” Dai, M.; Cheng, J.-X. United States Patent US 9,688,717 B2; June 27, 2017.
 
1. “Compounds, Compositions, and Methods for Cancer Therapy” Adams, D. J.; Dai, M.; Schreiber, S. L.; Hussain, M. M.; Boskovic, Z. V. United States Patent US 9,108,923 B2; August 18, 2015.