Anastasia Kharlamova

Education:     

Purdue University , West Lafayette , IN 47907     2007-present

Ph.D student in analytical chemistry, emphasizing mass spectrometry under the direction of Prof. Scott A. McLuckey.

University of Richmond , Richmond , VA              2003-2007

B.S. in chemistry and criminal justice

Research and Teaching:       

Purdue University , Department of Chemistry    
Teaching Assistant  

     Fall 2007 Chemistry 115

     Spring 2008 Chemistry 111

Undergraduate Research Experience:

University of Richmond , Department of Chemistry    

Fall 2005- Spring 2007

-         Synthesized the marine natural product Rigidin, and key functionalized pyrrole intermediates of other bioactive marine natural products utilizing vinylogous iminium salts.  Began the final synthesis of Rigidins B, C, and D and helped with the synthesis of Ningalin A. 

-         Utilized proton and carbon NMR, GC/DI-MS, and IR for structure determination, as well as automated flash chromatography for product purification and a microwave reactor for certain reactions

Academic & Professional Awards and Honors:

American Institute of Chemists Award                                 2007 University of Richmond

Academic Achievement Award                                              2007 University of Richmond

Dean's List                                                                             2007 University of Richmond

Arts and Science Summer Fellowship for Undergraduate Research

         A New and Novel Synthesis of the Marine Natural Product Ningalin A  

 2006 University of Richmond

Publications:

1)      S. Mooberry, K. Weiderhold, S. Dakshanamurthy, E. Hamel, E. Banner, A. Kharlamova, J. Hempel, J. Gupton, M. Brown, Molecular Pharmacology 72(2007) 132-140. "Indentification and characterization of a new tubulin-binding tetrasubstituted brominated pyrrole,"

2)      J. T.Gupton, E.J. Banner, A. B. Scharf, B. K. Norwood, R. P. Kanters, R. N. Dominey, J. E. Hempel, A. Kharlamova, I. Bluhn-Chertudi, C. R. Hickenboth, B. A. Little, M. D. Sartin, M. B. Coppock, K. E. Krumpe, B. S. Burnham, H. Holt, K. X. Du, K. M. Keertikar, A. Diebes, S. Ghassemi, and J. A. Sikorski, Tetrahedron 62(2006) 8243-8255. "The application of vinylogous iminium salt derivatives to an efficient synthesis of the pyrrole containing alkaloids Rigidin and Rigidin E."

3)   T. Huang, A. Kharlamova, J. Liu, and S. A. McLuckey, J. Am. Soc. Mass Spectrom., 276 (2008), 1832-1840.

"Ion Trap Collision-Induced Dissociation of Multiply Deprotonated RNA: c/y- Ions versus (a-B)/w- Ions."