Simpson Laboratory for Nonlinear Optics
Development and application of nonlinear optical instrumentation for studies of interfaces and chiral crystals.
Research Haikus
- Photothermal view. Fluorescence tells the tale. Bond vibrations.
- Image integrating. Data floods, algorithms. Chemistry revealed.
- Dynamic bleaching. Comb patterning enables. Diffusion mapping.
- New spectroscopy. Chiral, surface-selective. Electric dipole.
Recent Publications
125. "Analyzing Spatial Variations in Molecular Mobility in Hydrated Amorphous Drug-Polymer Blends Using Fourier Transform Fluorescence Recovery After Photobleaching and Image Segmentation” DOI: 10.1021/acs.jpcb.6c00122
124. "Pixel-Wise Diffusion Imaging by Structured Illumination Microscopy Fluorescence Recovery after Photobleaching (SIM-FRAP)" DOI: 10.1021/acs.analchem.5c01929
123. "Mid-infrared Optical Photothermal Interferometric Microscopy of Substrate-Supported Samples" DOI: 10.1021/acs.analchem.5c00959
122. "Consequences of Kramers-Kronic relations on Kleinman antisymmetric spectral observables: Chiral-specific sum frequency generation spectroscopy" DOI: 10.1063/5.0290341
121. "Theoretical Foundation for Interface-Specific Hyper-Rayleigh Scattering in Uniaxial Chiral Assemblies" DOI: 10.1021/acs.jpcb.4c08140
Latest News
July 20, 2026
Congratulations to Dr. Timothy Hwang for completing and passing his final thesis defense! Looking forward to seeing what’s next.
June 25, 2026
Congratulations to Camryn Gietl for passing her OP!
November 2025
Welcome to our two new first years, TJ Pinedo and Gabe Putman!
October 17, 2025
Farewell to our visiting scholar Fabian Schmidt and best of luck in your remaining time at Ruhr-Universität Bochum, Germany!


