Instrument development of Ion Soft-Landing Systems
Nano-DESI imaging of isomeric lipids via online photochemical derivatization of C=C Bonds
Role of viologen substituents and host size in the gas-phase fragmentation of cucurbituril–viologen host–guest complexes
Two-Channel Pneumatically-Assisted Microfluidic Probe for nano-DESI Imaging
Isomer-Selective Mass Spectrometry Imaging Using Nanospray Desorption Electrospray Ionization (Nano-DESI)
Staying Warm in our Parafilm Blankets
Ion Soft-Landing Instrument
February 2026
Raquel, Bethany, and Julia presented posters at the Gordon Research Conference on Gaseous Ions in Galveston.
Julia presented a talk at the Gordon Research Conference on Gaseous Ions in Galveston.
Julia presented an invited talk at the US HUPO 2026 conference in St. Louis.
Julia presented a seminar at Iowa State University.
Congratulations to Xilai on receiving the Thomas W. Keough Graduate Student Award from the Analytical Chemistry Division.
Congratulations to Govindi for passing her second-year seminar!
Congratulations to Julia for her promotion to Distinguished Professor of Chemistry!
January 2026
Govindi presented a poster and oral presentation and Renkai presented a poster at the ASMS winter conference in Santa Fe, NM.
December 2025
Julia gives a presentation on qMSI of proteins at Pacifichem in Honolulu, Hawaii.
Congratulations ot Anthony and Paul on passing their second-year seminars!
Overview
Our research at the interface of physical and analytical chemistry is focused on the advanced development of preparative and analytical mass spectrometry for applications in materials synthesis, imaging and chemical analysis of biological systems at a subcellular level, and environmental sciences.
Contact Us:
We are located on the 5th floor of the Brown Building
BRWN 5131A (Julia's office)
BRWN 5129/5133 (student/postdoc offices)
BRWN 5125/5135 (Labs)
Shipping/Mailing Address:
Department of Chemistry
Purdue University
560 Oval Drive
West Lafayette, IN 47907-2084
Phone: (765) 494-5464
Email: jlaskin@purdue.edu
Recent Publications
Imaging of Bioactive Lipid Isomers in Acetaminophen-Induced Liver Injury using Nano-DESI Tandem Mass Spectrometry
Weigand, M. R., Akakpo, J. Y., Hernly, E., Wali, S. N., Zheng, A., Ramachandran, A., Jaeschke, H., Laskin, J. J. Lipid Res. (2026).
https://doi.org/10.1016/j.jlr.2026.100995
Efficient and Cost-Effective Enzyme Deposition onto Tissues for Mass Spectrometry Imaging of N-Glycans Using a Mini-Humidifier
Sveen, E., Moore, A. M., Weigand, M. R., Laskin, J. J. Am. Soc. Mass Spectrom. 37 (3), 746-753 (2026).
https://doi.org/10.1021/jasms.5c00435
Quantitative Mass Spectrometry Imaging of Intact Proteins in Tissues
Iqfath, M., Swansiger, A. K., Yang, M., Miller, L., Moore, A. M., Hernly, E., Bai, Y., Zhang, Z.-Y., Prell, J. S., Laskin, J. Anal. Chem. (2026).
https://doi.org/10.1021/acs.analchem.5c05187
Unraveling Ligand-Driven Isomerism in Redox-Active Mixed-Ligand Polyoxometalates Using Ion Mobility Spectrometry
Wilson, S., Li, X., Gandhi, V. D., Johnson, A., Schreiber, E., Ryan, L., Sertse, L., Larriba-Andaluz, C., Matson, E., Laskin, J. ACS Nano, 44, 38544-38552 (2025).
https://doi.org/10.1021/acsnano.5c12468
Role of Viologen Substituents and Host Size in the Gas-Phase Fragmentation of Cucurbituril-Viologen Host-Guest Complexes
Samayoa-Oviedo, H., Hristov, D., Phillips, B., Laskin, J. " Phys. Chem. Chem. Phys. 27, 24713 (2025).
https://doi.org/10.1039/D5CP03029C