2025 Group Photo
Two-Channel Pneumatically-Assisted Microfluidic Probe for nano-DESI Imaging
Instrument development of Ion Soft-Landing Systems
Nano-DESI imaging of isomeric lipids via online photochemical derivatization of C=C Bonds
Journal article in Angewandte Chemie
Staying Warm in our Parafilm Blankets
Ion Soft-Landing Instrument
November 2025
Welcome to our new group members: Naina Beishembieva, Josh Koval, and Yuna Chen, as well as Austin Pronk, who is co-advised by Dr. Alex Laskin!
Bethany and Rahat attended the ASMS Fall Workshop in Seattle, Washington.
Bethany received the ASMS travel award to attend the ASMS Fall Workshop!
October 2025
Julia gives a plenary lecture at the Swiss Group for Mass Spectrometry (SGMS) meeting in Beatenberg and a tutorial lecture at the SGMS School on ionization in mass spectrometry.
Xilai gave a poster presentation at the Federation of Analytical Chemistry and Spectroscopy Societies SCiX 2025 in Covington, Kentucky.
Julia gives a plenary lecture at the International Mass Spectrometry Imaging Society Conference in UC Davis.
September 2025
Nazifa and Mushfeqa gave oral presentations at the International Mass Spectrometry Imaging Society Conference in UC Davis.
Alyssa, Tom, Bethany, Renkai, Rahat, Paul, Govindi, and Anthony all gave poster presentations at the 2025 Turkey Run Analytical Chemistry Conference.
Julia gives a keynote lecture at the International Single Cell Mass Spectrometry Meeting in Chicago.
Congratulations to all of our third year students, Xindi, Tom, and Bethany on passing their OPs!
Overview
Our research at the interface of physical and analytical chemistry is focused on the advanced development of preparative and analytical mass spectrometry for applications in materials synthesis, imaging and chemical analysis of biological systems at a subcellular level, and environmental sciences.
Contact Us:
We are located on the 5th floor of the Brown Building
BRWN 5131A (Julia's office)
BRWN 5129/5133 (student/postdoc offices)
BRWN 5125/5135 (Labs)
Shipping/Mailing Address:
Department of Chemistry
Purdue University
560 Oval Drive
West Lafayette, IN 47907-2084
Phone: (765) 494-5464
Email: jlaskin@purdue.edu
Recent Publications
Unraveling Ligand-Driven Isomerism in Redox-Active Mixed-Ligand Polyoxometalates Using Ion Mobility Spectrometry
Wilson, S., Li, X., Gandhi, V. D., Johnson, A., Schreiber, E., Ryan, L., Sertse, L., Larriba-Andaluz, C., Matson, E., Laskin, J. ACS Nano, (2025).
https://doi.org/10.1021/acsnano.5c12468
Role of Viologen Substituents and Host Size in the Gas-Phase Fragmentation of Cucurbituril-Viologen Host-Guest Complexes
Samayoa-Oviedo, H., Hristov, D., Phillips, B., Laskin, J. " Phys. Chem. Chem. Phys. (2025).
https://doi.org/10.1039/D5CP03029C
Multimodal Nano-DESI Mass Spectrometry Imaging Reveals Phospholipids Accumulation in and around Amyloid Plaques in Alzheimer's Disease
Yang, M., Tang, X., Iqfath, M., Hernly, E., Unsihuay, D., Manchanda, P., Sharma, K., Qu, Z., Hu, H., Beveridge, C., Chopra, G., Laskin, J. ACS Chem. Neurosci. (2025).
https://doi.org/10.1021/acschemneuro.5c00144
Isomer-Selective Mass Spectrometry Imaging Using Nanospray Desorption Electrospray Ionization (Nano-DESI)
Amer S., Jiang L., Iqfath M., Weigand, M. R., Laskin J. Acc. Chem. Res., 58, 3281-3293 (2025).
https://doi.org/10.1021/acs.accounts.5c00532
Constant Distance Mode Mass Spectrometry Imaging with a Confocal Sensor
Zhang, T., Hilger, R. T., Jiang, L.-X., Laskin, J. Anal. Chem, 97, 14116-14120 (2025).
https://doi.org/10.1021/acs.analchem.5c00742