Dr. Chi Zhang Research Group

We play with photons!

Publications

PEER-REVIEWED JOURNAL PUBLICATIONS:

(* corresponding author, # equal contribution co-first author)

2022

48. M.G.Clark, G. Gonzalez, J. Aldana-Mendoza, M.S. Carlsen, G. Eakins, and C. Zhang*. "Real-time precision opto-control of chemical processes in live cells". 

2021

47. C. Zhang* and J. A. Aldana-Mendoza. "Coherent Raman scattering microscopy for chemical imaging of biological systems", J. Phys. Photon. 3, 032002 (2021) Link

BOOK CHAPTERS:

C. Zhang* "Chapter 15. SRS flow and image cytometry", Stimulated Raman Scattering Microscopy. Elsevier, 1st Edition - December 4, 2021

 

------- Before joining Purdue Chemistry ------

46. P. Mukherjee, E. Aksamitiene, A. Alex, J. Shi, K. Bera, C. Zhang, D. Spillman, M. Marjanovic, M. Fazio, P.P. Seth, K. Frazier, S.R. Hood, and S.A. Boppart*. "Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman Imaging", Nucleic Acid Ther., DOI: 10.1089/nat.2021.0059. 

45. C. Zhang and S. A. Boppart*. "Tracking the formation and degradation of fatty-acid-accumulated mitochondria using label-free chemical imaging", Sci. Rep. 11, 6671 (2021) Link

44. C. Zong, C. Zhang, P. Lin, J. Yin, Y. Bai, H. Lin, B. Ren*, and J. Cheng*. "Real-time imaging of surface chemical reactions by electrochemical photothermal reflectance microscopy", Chem. Sci., 12, 1930-1936 (2021) Link

43. 43. C. Zhang and S. A. Boppart*. "Dynamic signatures of lipid droplets as new markers to quantify cellular metabolic changes", Anal. Chem., 92, 15943–15952 (2020). Link 

42. K. Huang#, J. Li#, C. Zhang#, Y. Tan, J.X. Cheng*. “Multiplex stimulated Raman scattering imaging cytometry reveals cancer metabolic signatures in a spatially and spectrally resolved manner”, iScience, 23, 100953, (2020).

41. C. Zong, R. Premasiri, H. Lin, Y. Huang, C. Zhang, C. Yang, B. Ren, L.D. Ziegler, J.X. Cheng*. “Plasmon-enhanced stimulated Raman scattering microscopy with Single-molecule detection sensitivity”, Nat. Commun., 10, 5318, (2019).

40. J.H. Lee#, J.J. Rico-Jimenez#, C. Zhang, A. Alex, E.J. Chaney, R. Barkalifa, D.R. Spillman, M. Marjanovic, Z. Arp, S.R. Hood, and S.A. Boppart*. “Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin”, Biomed. Opt. Express, 10, 5421-5444 (2019).

39. X. Chen*, S.P. Zhu, H.Y. Wang, C.P. Bao, D.F. Yang, C. Zhang, P. Lin, J.X. Cheng, Y.H. Zhan, J.M. Liang, and J. Tian*. “Accelerated stimulated Raman projection tomography by sparse reconstruction from sparse-view data”, IEEE Trans. Biomed. Eng., 10.1109/TBME.2019.2935301 (2019).

38. Y. Sun, H. Tu, S. You, C. Zhang, Y. Liu, and S.A. Boppart*. “Detection of weak near-infrared optical imaging signals under ambient light by optical parametric amplification”, Opt. Lett., 17, 4391-4394, (2019).

37. C. Zhang, J.X. Cheng*, “Coherent Raman scattering imaging: the future is bright”, Appl. Phys. Lett. Photonics, 3, 090901 (2018).

36. Y. Urasaki#, C. Zhang#, J.X. Cheng, T.T. Le, “Quantitative assessment of liver steatosis and affected pathways with molecular imaging and proteomic profiling”, Sci. Rep., 8, 3606, (2018).

35. C. Zhang#, J. Li#, L. Lan, and J.X. Cheng* “Quantification of lipid metabolism through the dynamics of lipid droplets in living cells by stimulated Raman scattering imaging”, Anal. Chem., 89, 4502-4507, (2017).

34. X. Chen#, C. Zhang#, P. Lin, K. Huang, J. Liang, J. Tian, and J.X. Cheng* “Volumetric chemical imaging by stimulated Raman projection microscopy and tomography”, Nat. Commun., 8, 15117, (2017).

33. C. Zhang* “Sum frequency generation vibrational spectroscopy for characterization of buried polymer interfaces” Focal Point Review, Appl. Spectrosc., 71, 1717-1749 (2017).

32. C. Zhang#, K. Huang#, B. Rajwa, J. Li, S. Yang, H. Lin, C. Liao, G. Eakins, S. Kuang, V. Patsekin, J.P. Robinson, J.X. Cheng* “Label-free single-particle analysis by stimulated Raman scattering flow cytometry”, Optica, 4, 103-109 (2017).

31. X. Lu*, C. Zhang, Z. Chen* “Studying polymer surfaces and interfaces with sum frequency generation vibrational spectroscopy”, Anal. Chem., 89, 466-489 (2016).

30. D. Zhang, C. Li, C. Zhang, M. N. Slipchenko, G. Eakins, J.X. Cheng*, “Depth-resolved mid-infrared photothermal imaging of living cells and organisms with sub-micro spatial resolution”, Sci. Adv., 2, e1600521. (2016).  

29. J. Jasensky, A. Boughton, A. Khamaladze, J. Ding, C. Zhang, J. Swain, G. Smith, Z. Chen*, G. Smith*, “Live-cell quantification and comparison of mammalian oocyte cytosolic lipid content between species during development, and in relation to body composition using nonlinear vibrational microscopy”, Analyst, 141, 4694-4706 (2016).

28. C. Zhang, D. Zhang, J. Cheng*, “Coherent Raman scattering microscopy in biology and medicine”, Annu. Rev. Biomed. Eng., 17, 415-445 (2015).

27. C. Zhang*, J. Jasensky, Z. Chen*, “Multi-reflection sum frequency generation vibrational spectroscopy”, Anal. Chem., 87, 8157-8164 (2015).

26. C. Zhang*, J. Wang, J. Jasensky, Z. Chen, “Molecular orientation analysis of alkyl methylene groups from quantitative coherent anti-Stokes Raman scattering spectroscopy”, J. Phys. Chem. Lett., 6, 1369-1374 (2015).

25. P. Hu, X. Zhang, C. Zhang, Z. Chen*, “Molecular interactions between gold nanoparticles and model cell membranes”, Phys. Chem. Chem. Phys., 17, 9873-9884 (2015).

24. A. Khmaladze*, J. Jasensky, E. Price, C. Zhang, A. Boughton, X. Han, E. Seeley, X. Lu, M. M. Banaszak Holl, Z. Chen*, “Hyperspectral imaging and characterization of live cells by broadband coherent anti-Stokes Raman scattering (CARS) microscopy with singular value decomposition (SVD) analysis”, Appl. Spectrosc., 68, 1116-1122 (2014).

23. F-G Wu*, P. Yang, C. Zhang, B. Li, X. Han, M. Song, and Z. Chen*, “Molecular interactions between amantadine and model cell membranes”, Langmuir, 30, 8491-8499 (2014).

22. F-G Wu*, P. Yang, C. Zhang, X. Han, M. Song, and Z. Chen*, “Investigation of drug–model cell membrane interactions using sum frequency generation vibrational spectroscopy: a case study of chlorpromazine”, J. Phys. Chem. C, 118, 17538-17548 (2014).

21. C. Zhang*, J. Wang, B. Ding, J. Jasensky, “Quantitative spectral analysis of coherent anti-Stokes Raman scattering signal: C-H stretching modes of the methyl group”, J. Phys. Chem. B, 118, 7647-7656 (2014). 

20. C. Zhang, J. Jasensky, C. Leng, C. Del Grosso, G. D. Smith, J. Wilker and Z. Chen*, “Sum frequency generation vibrational spectroscopic studies on buried heterogeneous biointerfaces”, Opt. Lett., 39, 2715-2718 (2014).

19. J. Myers, C. Zhang, C. Chen, Z. Chen*, “Influence of casting solvent on Phenyl ordering at the surface of spin cast polymer thin films”, J. Colloid Interface Sci., 423, 60-66 (2014).

18. J. Myers, C. Zhang, K.W. Lee, J.M. Williamson, Z. Chen*, “Hygrothermal aging effects on buried molecular structures at epoxy interfaces”, Langmuir, 30, 165-171 (2014).

17. C. Zhang, J. Myers, Z. Chen*, “Molecular behavior at buried epoxy/poly(ethylene terephthalate) interfaces”, Langmuir, 30, 12541-12550 (2014).

16. C. Zhang, F. Wu, P. Hu, Z. Chen*, “Interaction of polyethylenimine with model cell membranes studied by linear and nonlinear spectroscopic techniques”, J. Phys. Chem. C, 118, 12195-12205 (2014).

15. X. Zhang, C. Zhang, J. Hankett, Z. Chen*, "Molecular surface structural changes of plasticized PVC materials after plasma treatment", Langmuir, 29, 4008-4018 (2013).

14. J. M. Hankett, Y. Liu, X. Zhang, C. Zhang, Z. Chen*, "Molecular level studies of polymer behaviors at the water interface using sum frequency generation vibrational spectroscopy", J. Polym. Sci. Part B Polym. Phys., 51, 311-328 (2013).

13. C. Zhang, J. Myers, Z. Chen*, "Elucidation of molecular structures at buried polymer interfaces and biological interfaces using sum frequency generation vibrational spectroscopy", Soft Matter, 9, 4738-4761 (2013).  

12. C. Zhang, Z. Chen*, "Quantitative molecular level understanding of ethoxysilane at poly(dimethyl siloxane)/polymer interfaces", Langmuir, 29, 610-619 (2013).

11. C. Zhang, Z. Chen*, "Probing molecular structures of poly(dimethyl siloxane) at buried interfaces in situ", J. Phys. Chem. C, 117, 3903-3914 (2013).

10. C. Zhang, J. Hankett, Z, Chen*, "Molecular level understanding of adhesion mechanisms at the epoxy/polymer interfaces", ACS Appl. Mater. Interfaces, 4, 3730-3737 (2012).

9. C. Zhang, N. E. Shephard, S. M. Rhodes, Z. Chen*, "Head group effect on silane structures at polymer/silane and polymer/polymer interfaces and their relations to adhesion", Langmuir, 28, 6052-6059 (2012).

8. J. M. Hankett, C. Zhang, Z. Chen*, "Sum frequency generation and coherent anti-Stokes Raman spectroscopic studies on plasma-treated plasticized polyvinyl chloride films", Langmuir, 28, 4654-4662 (2012).

7. C. Zhang, Y.Y. Zhang, M.L. Hu*, S.J. Wang, Y.J. Song, L. Chai, C.Y. Wang, "Wavelength tunable, high energy femtosecond laser pulses directly generated from large-mode-area photonic crystal fiber", Opt. Commun., 285, 2715-2718 (2012).

6. C. Zhang*, J. Wang, A. Khmaladze, Y. Liu, B. Ding, J. Jasensky, Z. Chen, "Examining surface and bulk structures using combined nonlinear vibrational spectroscopies", Opt. Lett., 36, 2272-2274 (2011).

5. A. Khmaladze*, R. L. Matz, C. Zhang, T. Wang, M. M. Banaszak Holl, Z. Chen, "Dual-wavelength linear regression phase unwrapping in three-dimensional microscopic images of cancer cells", Opt. Lett., 36, 912-914 (2011).

4. Y.Y. Zhang, C. Zhang, M.L. Hu*, Y.J. Song, S.J. Wang, L. Chai, and C.Y. Wang, "High-energy subpicosecond pulse generation from a mode-locked Yb-doped large-mode-area photonic crystal fiber laser with fiber facet output", IEEE Photonics Technol. Lett., 22, 350-352 (2010).

3. Y.Y. Zhang, C. Zhang, M.L. Hu*, S.J. Wang, Y.J. Song, L. Chai, C.Y. Wang, "Mechanism and elimination of spectrum filtering in a high power mode-locked fibre laser with a free output coupler", Chin. Phys. B, 19: 014212 (2010).

2. C. Zhang, M.L. Hu*, Y. Song, X. Zhang, L. Chai, C.Y. Wang, "An Yb-doped large-mode-area photonic crystal fiber mode-locking laser with free output coupler", Acta. Phys. Sin., 58, 7727-7734 (2009).

1. Y.J. Song, M.L. Hu*, C. Zhang, L. Chai, C.Y. Wang, "High pulse energy femtosecond large-mode-area photonic crystal fiber laser", Chin. Sci. Bull., 53, 3741-3745 (2008).

PUBLICATION LINK:

https://scholar.google.com/citations?user=Ahxte2kAAAAJ&hl=en