Medicinal Chemistry Articles
(236) Alkylthialactonization: A novel protocol for access to either diastereoisomer of α-(thiomethyl)-γ-butyrolactones
Nicponski, D.R., Ramachandran, P. V., Tetrahedron Lett., 2023, 124(11), 154605
DOI: 10.1016/j.tetlet.2023.154605
(222) β,γ-Diaryl α-methylene-γ-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus
Hamann, H. J.; Abutaleb, N. S.; Pal, R.; Seleem, M. N.; Ramachandran, P. V., Bioorganic Chemistry, 2020, 104, 104183
DOI: 10.1016/j.bioorg.2020.104183
(204) Factors influencing the cytotoxicity of a-methylene-g -hydroxy esters against pancreatic cancer
Matthew A Helppi; Arlie Lehmkuhler; Jennifer M Marchi; C. Max Schmidt; Michele T Yip-Schneider Bioorg. Med. Chem. Lett. 2015, 25, 4270–4273.
DOI:10.1016/j.bmcl.2015.07.087
(202) Asymmetric Synthesis of γ–Arylsubstituted GABA Derivatives via a Highly Diastereoselective Rh- Catalyzed Boronic Acid Addition at Room Temperature
Ramachandran PV, Mitsuhashi, W.; Biswas, B. Org. Chem. Front. 2015, 2, 885-889.
DOI: 10.1039/C5QO00133A
(191) Diastereoselective Synthesis of α-(Aminomethyl)-γ-Butyrolactones via a Catalyst-free Aminolactonization
Ramachandran, P. V.; Nicponski, D. R. Chem. Commun. 2014, 0000.
DOI: 10.1039/c4cc05765a
(188) Syntheses of b- and g-Fluorophenyl cis- and trans-a-Methylene-g-Butyrolactones
Ramachandran, P. V.; Nair, H. N. G.; Gagare, P. D. Tetrahedron Lett. 2014, 55, 5722-5726.
DOI: 10.1016/j.tetlet.2014.07.106
(180) Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activities.
Ramachandran, P. V.; Nicponski, D. R. Nair, H. N. G.; Gagare, P. D.; Helppi, M.; Schmidt, C. M.; Yip-Schneider, M. T Bioorg. Med. Chem. Lett. 2013, 23, 6911-6914.
(176) Focusing on Boron in Medicinal Chemistry.
Ramachandran, P. V. Future Med. Chem. 2013, 5, 611-612.
(173) The first synthesis of a borylated α-methylene-γ-butyrolactone
Ramachandran, P. V.; Nicponski, D. R.; Drolet, M. P.; Schmidt, C. M.; Yip-Schneider, M. T. Future Med. Chem. 2013, 5, 633-639.
(172) Prevention of Posttraumatic Axon Sprouting by Blocking Collapsin Response Mediator Protein 2-Mediated Neurite Outgrowth and Tubulin Polymerization
Wilson, S. M.; Xiong, W.; Wang, Y.; Ping, X.; Head, J. D.; Brittain, J. M.; Gagare, P. D.; Ramachandran, P. V. ; Jin, X. ; Khanna, R. Neuroscience, 2012, 210, 451-466.
(164) The role of solvent selection at exploratory and production stages in the pharmaceutical industry.
Nicponski, D. R.; Ramachandran, P. V. Future Med. Chem. 2011, 3, 1469-73.
(157) Welcome to GABAergic Drugs.
Ramachandran, P. V.; Shekhar, A. Future Med. Chem. 2011, 3, 139-40.
(156) Synthesis of Ring-substituted N-benzyl g-phenyl GABA derivatives via reductive amination.
Ramachandran, P. V.; Sakavuyi, K.; Mistry, H. Future Med. Chem. 2011, 3, 155-162.