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Medicinal Chemistry Articles

(222)   β,γ-Diaryl α-methylene-γ-butyrolactones as potent antibacterials against methicillin-resistant Staphylococcus aureus

Hamann, H. J.; Abutaleb, N. S.; Pal, R.; Seleem, M. N.; Ramachandran, P. V., Bioorganic Chemistry, 2020, 104, 104183
DOI: 10.1016/j.bioorg.2020.104183

(204)   Factors influencing the cytotoxicity of a-methylene-g -hydroxy esters against pancreatic cancer

Matthew A Helppi; Arlie Lehmkuhler; Jennifer M Marchi; C. Max Schmidt; Michele T Yip-Schneider Bioorg. Med. Chem. Lett. 2015, 25, 4270–4273.
DOI:10.1016/j.bmcl.2015.07.087

(202)   Asymmetric Synthesis of γ–Arylsubstituted GABA Derivatives via a Highly Diastereoselective Rh- Catalyzed Boronic Acid Addition at Room Temperature

Ramachandran PV, Mitsuhashi, W.; Biswas, B. Org. Chem. Front. 2015, 2, 885-889.
DOI: 10.1039/C5QO00133A

(191)   Diastereoselective Synthesis of α-(Aminomethyl)-γ-Butyrolactones via a Catalyst-free Aminolactonization

Ramachandran, P. V.; Nicponski, D. R. Chem. Commun. 2014, 0000.
DOI: 10.1039/c4cc05765a

(188)   Syntheses of b- and g-Fluorophenyl cis- and trans-a-Methylene-g-Butyrolactones

Ramachandran, P. V.; Nair, H. N. G.; Gagare, P. D. Tetrahedron Lett. 2014, 55, 5722-5726.
DOI: 10.1016/j.tetlet.2014.07.106

(180)   Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activities.

Ramachandran, P. V.; Nicponski, D. R. Nair, H. N. G.; Gagare, P. D.; Helppi, M.; Schmidt, C. M.; Yip-Schneider, M. T Bioorg. Med. Chem. Lett. 2013, 23, 6911-6914.

(176)   Focusing on Boron in Medicinal Chemistry.

Ramachandran, P. V. Future Med. Chem. 2013, 5, 611-612.

(173)   The first synthesis of a borylated α-methylene-γ-butyrolactone

Ramachandran, P. V.; Nicponski, D. R.; Drolet, M. P.; Schmidt, C. M.; Yip-Schneider, M. T. Future Med. Chem. 2013, 5, 633-639.

(172)   Prevention of Posttraumatic Axon Sprouting by Blocking Collapsin Response Mediator Protein 2-Mediated Neurite Outgrowth and Tubulin Polymerization

Wilson, S. M.; Xiong, W.; Wang, Y.; Ping, X.; Head, J. D.; Brittain, J. M.; Gagare, P. D.; Ramachandran, P. V. ; Jin, X. ; Khanna, R. Neuroscience, 2012, 210, 451-466.

(164)   The role of solvent selection at exploratory and production stages in the pharmaceutical industry. 

Nicponski, D. R.; Ramachandran, P. V. Future Med. Chem. 2011, 3, 1469-73.

(157)   Welcome to GABAergic Drugs.

Ramachandran, P. V.; Shekhar, A.  Future Med. Chem. 2011, 3, 139-40.

(156)   Synthesis of Ring-substituted N-benzyl g-phenyl GABA derivatives via reductive amination.

Ramachandran, P. V.; Sakavuyi, K.; Mistry, H. Future Med. Chem. 2011, 3, 155-162.