Low Research Lab


  1. Standardization and optimization of intraoperative molecular imaging for identifying primary pulmonary adenocarcinomas. Predina, J.D., Okusanya, O., Newton, A.D., Low, PS and Singhal, S. Molecular Imaging and Biology. 20(1), pp.131-138 (2018)

  2. Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate.  Chandrupatla DMSH, Jansen G, Mantel E, Low PS, Matsuyama T, Musters RP, Windhorst AD, Lammertsma AA, Molthoff CFM, van der Laken CJ1. Contrast Media Mol Imaging 10:1155 (2018)

  3. Fluorescence-guided surgery of cancer: applications, tools and perspectives. Low PS, Singhal S, Srinivasarao M. Curr Opin Chem Biol. 45:64-72 (2018)

  4. An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas. Predina JD, Newton AD, Xia L, Corbett C, Connolly C, Shin M, Sulyok LF, Litzky L, Deshpande C, Nie S, Kularatne SA, Low PS, Singhal S. Oncotarget. 9:13517-13529 (2018)

  5. Synthesis and Evaluation of a Novel 64Cu- and 67Ga-Labeled Neurokinin 1 Receptor Antagonist for in Vivo Targeting of NK1R-Positive Tumor Xenografts. Zhang H, Kanduluru AK, Desai P, Ahad A, Carlin S, Tandon N, Weber WA, Low PS. Bioconjug Chem. 10.1021 (2018)

  6. New Mechanism for Release of Endosomal Contents: Osmotic Lysis via Nigericin-Mediated K+/H+ Exchange.  Rangasamy L, Chelvam V, Kanduluru AK, Srinivasarao M, Bandara NA, You F, Orellana EA, Kasinski AL, Low PS. Bioconjug Chem. 10.1021 (2018)

  7. Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies. Shen J, Hu Y, Putt KS, Singhal S, Han H, Visscher DW, Murphy LM, Low PS. Oncotarget. 9:4485-4495 (2017)

  8. Folate receptor-α targeted near-infrared fluorescence imaging in high-risk endometrial cancer patients: a tissue microarray and clinical feasibility study.  Boogerd LSF, Hoogstins CES, Gaarenstroom KN, de Kroon CD, Beltman JJ, Bosse T, Stelloo E, Vuyk J, Low PS, Burggraaf J, Vahrmeijer AL. Oncotarget. 9: 791-801 (2017)

  9. Selective liposome targeting of folate receptor positive immune cells in inflammatory diseases. Poh S, Chelvam V, Ayala-López W, Putt KS, Low PS.  Nanomedicine. 14:1033-1043 (2018)

  10. A Phase I Clinical Trial of Targeted Intraoperative Molecular Imaging for Pulmonary Adenocarcinomas. Predina JD, Newton AD, Keating J, Dunbar A, Connolly C, Baldassari M, Mizelle J, Xia L, Deshpande C, Kucharczuk J, Low PS, Singhal S.  Ann Thorac Surg. 105:901-908 (2018)

  11. Identification of a Folate Receptor-Targeted Near-Infrared Molecular Contrast Agent to Localize Pulmonary Adenocarcinomas. Predina JD, Newton AD, Connolly C, Dunbar A, Baldassari M, Deshpande C, Cantu E 3rd, Stadanlick J, Kularatne SA, Low PS, Singhal S. Mol Ther. 26:390-403 (2018)

  12. Folate-PEG-NOTA-Al18F: A New Folate Based Radiotracer for PET Imaging of Folate Receptor-Positive Tumors. Chen Q, Meng X, McQuade P, Rubins D, Lin SA, Zeng Z, Haley H, Miller P, González Trotter D, Low PS. Mol Pharm. 14:4353-4361 (2017)

  13. Folate-conjugated liposomes target and deliver therapeutics to immune cells in a rat model of rheumatoid arthritis. Poh S, Chelvam V, Kelderhouse LE, Ayala-López W, Vaitilingam B, Putt KS, Low PS. Nanomedicine (Lond).  12:2441-2451 (2017)

  14. Development of a Ligand-Targeted Therapeutic Agent for Neurokinin-1 Receptor Expressing Cancers. Kanduluru AK, Low PS. Mol Pharm. 14:3859-3865 (2017)

  15. Evaluation of a Centyrin-Based Near-Infrared Probe for Fluorescence-Guided Surgery of Epidermal Growth Factor Receptor Positive Tumors.  Mahalingam SM, Dudkin VY, Goldberg S, Klein D, Yi F, Singhal S, O'Neil KT, Low PS. Bioconjug Chem  28:2865-2873 (2017)

  16. Ligand-Targeted Drug Delivery. Srinivasarao M, Low PS. Chem Rev117:12133-12164 (2017)

  17. Folate-Targeted Dendrimers Selectively Accumulate at Sites of Inflammation in Mouse Models of Ulcerative Colitis and Atherosclerosis. Poh S, Putt KS, Low PS.  Biomacromolecules.  18:3082-3088 (2017)

  18. Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging.  Lee JYK, Cho SS, Zeh R, Pierce JT, Martinez-Lage M, Adappa ND, Palmer JN, Newman JG, Learned KO, White C, Kharlip J, Snyder P, Low PS, Singhal S, Grady MS.  J Neurosurg  Aug 25:1-14 (2017)

  19. FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer.  Orellana EA, Tenneti S, Rangasamy L, Lyle LT, Low PS, Kasinski AL. Sci Transl Med.  9:401 (2017)

  20. Conjugation Dependent Interaction of Folic Acid with Folate Binding Protein. Merzel RL, Frey C, Chen J, Garn R, van Dongen M, Dougherty CA, Kandaluru AK, Low PS, Marsh ENG, Banaszak Holl MM.  Bioconjug Chem. 28:2350-2360 (2017)

  21. Syk inhibitors interfere with erythrocyte membrane modification during P falciparum growth and suppress parasite egress.  Pantaleo A, Kesely KR, Pau MC, Tsamesidis I, Schwarzer E, Skorokhod OA, Chien HD, Ponzi M, Bertuccini L, Low PS, Turrini FM.  Blood.  130:1031-1040 (2017)

  22. In-vivo monitoring of anti-folate therapy in arthritic rats using [18F]fluoro-PEG-folate and positron emission tomography. Chandrupatla DMSH, Jansen G, Vos R, Verlaan M, Chen Q, Low PS, Windhorst AD, Lammertsma AA, van der Laken CJ, Molthoff CFM. Arthritis Res Ther. 19(1):114 (2017)

  23. Synthesis and evaluation of a ligand targeting the mu and delta opioid receptors for drug delivery to lung cancer. Li G, Low PS. Bioorg Med Chem Lett. 27(9):2074-2078 (2017)

  24. Intraoperative near-infrared fluorescence imaging targeting folate receptors identifies lung cancer in a large-animal model. Keating JJ, Runge JJ, Singhal S, Nims S, Venegas O, Durham AC, Swain G, Nie S, Low PS, Holt DE. Cancer. 123(6):1051-1060 (2017)

  25. Healing efficacy of fracture-targeted GSK3β inhibitor-loaded micelles for improved fracture repair. Low SA, Galliford CV, Jones-Hall YL, Roy J, Yang J, Low PS, Kopeček J. Nanomedicine (Lond). 12(3):185-193 (2017).

  26. Intraoperative molecular imaging to identify lung adenocarcinomas. Newton AD, Kennedy GT, Predina JD, Low PS, Singhal S. J Thorac Dis. 8(Suppl 9):S697-S704 (2016).

  27. Separation and dual detection of prostate cancer cells and protein biomarkers using a microchip device. Huang W, Chang CL, Brault ND, Gur O, Wang Z, Jalal SI, Low PS, Ratliff TL, Pili R, Savran CA. Lab Chip. 17(3):415-428 (2017).

  28. Folate-hapten mediated immunotherapy synergizes with vascular endothelial growth factor receptor inhibitors in treating murine models of cancer. Bandara NA, Bates CD, Lu Y, Hoylman EK, Low PS. Mol Cancer Ther. 16(3):461-468 (2017)

  29. Evaluation of nonpeptidic ligand conjugates for treatment of hypoxic and carbonic anhydrase IX-expressing cancers. Lv PC, Roy J, Putt KS, Low PS. Mol Cancer Ther. 16(3):453-460 (2017)

  30. Novel Use of Folate-Targeted Intraoperative Fluorescence, OTL38, in Robot-Assisted Laparoscopic Partial Nephrectomy: Report of the First Three Cases. Shum SC, Bahler CD, Low PS, Ratliff TL, Kheyfets SV, Natarajan JP, Sandusky GE, Sundaram CP. J Endourol Case Rep. 2(1):189-197 (2016).

  31. Reversible binding of deoxyhemoglobin to band 3 constitutes the molecular switch that mediates O2 regulation of erythrocyte properties. Chu H, McKenna MM, Krump NA, Zheng S, Mendelsohn L, Thein SL, Garrett LJ, Bodine DM, Low PS. Blood. 128(23):2708-2716 (2016).

  32. Global transformation of membrane properties via engagement of an SH2-like sequence in band 3. Puchulu-Campanella E, Turrini F, Li YH, Low PS. Proc Natl Acad Sci. 113(48):13732-13737 (2016).

  33. Inhibition of an erythrocyte tyrosine kinase with imatinib prevents Plasmodium falciparum egress and terminates parasitemia. Kesely KR, Panataleo A, Turrini FM, Olupot-Olupot P, Low PS. PLoS One. 11(10):e0164895 (2016).

  34. Single molecule studies of the diffusion of band 3 in erythrocytes with hemoglobin pathologies. Spector J, Kodippili GC, Ritchie K, Low PS. PLoS One. 11(9):e0162514 (2016).

  35. Diffusion of glycophorin A in human erythrocytes. Giger K, Habib I, Ritchie K, Low PS. BBA-Biomembranes. 1858(11):2839-2845 (2016).

  36. Design, synthesis and evaluation of a neurokinin 1 receptor-targeted near IR dye for fluorescence guided surgery of neuroendocrine cancers. Kanduluru AK, Srinivasarao M, Low PS. Bioconjug Chem. 27(9):2157-65 (2016).

  37. Identification of adducin-binding residues on the cytoplasmic domain of erythrocyte membrane protein, band 3. Franco T, Chu H, Low PS. Biochem J. 473(19):3147-58 (2016).

  38. Evaluation of nonpeptidic ligand conjugates for SPECT imaging of hypoxic and carbonic anhydrase IX-expressing cancers. Lv PC, Putt KS, Low PS. Bioconjug Chem. 27(7):1762-9 (2016).

  39. Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17. Tummers QR, Hoogstins CE, Gaarenstroom KN, de Kroon CD, van Poelgeest MI, Vuyk J, Bosse T, Smit VT, van de Velde CJ, Cohen AF, Low PS, Burggraaf J, Vahrmeijer AL. Oncotarget. 7(22):32144-55 (2016).

  40. A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer. Hoogstins CE, Tummers QR, Gaarenstroom KN, de Kroon CD, Trimbos JB, Bosse T, Smit VT, Vuyk J, van de Velde CJ, Cohen AF, Low PS, Burggraaf J, Vahrmeijer AL. Clin Cancer Res. 15;22(12):2929-38 (2016).

  41. Optimization of folate-targeted immunotherapy for the treatment of experimental arthritis. Varghese B, Paulos C, Low PS. Inflammation. 39(4):1345-53 (2016).

  42. Direct In Vivo Evidence of Activated Macrophages in Human Osteoarthritis. Kraus VB, McDaniel G, Huebner JL, Stabler TV, Pieper CF, Shipes SW, Petry NA, Low PS, Shen J, McNearney TA, Mitchell P. Osteoarthritis Cartilage. 24(9):1613-21 (2016).

  43. Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients. Boogerd LS, Boonstra MC, Beck AJ, Charehbili A, Hoogstins CE, Prevoo HA, Singhal S, Low PS, van de Velde CJ, Vahrmeijer AL. Oncotarget. 7(14):17442-54 (2016).

  44. Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue. Roy J, Putt KS, Coppola D, Leon ME, Khalil FK, Centeno BA, Clark N, Stark VE, Morse DL, Low PS. Oncotarget. 7(12):14605-15 (2016).

  45. Synthesis and Preclinical Evaluation of Folate-NOTA-AI18F for PET Imaging of Folate Receptor-Positive Tumors. Chen Q, Meng X, McQuade P, Rubins D, Lin SA, Zeng Z, Haley H, Miller P, González Trotter D, Low PS. Mol Pharm 13(5):1520-7 (2016).

  46. Evaluation of a Carbonic Anhydrase IX-Targeted Near-Infrared Dye for Fluorescence-Guided Surgery of Hypoxic Tumors. Lv PC, Roy J, Putt KS, Low PS. Mol Pharm 13(5):1618-25 (2016).

  47. Synthesis and Evaluation of Folate-Conjugated Phenanthraquinones for Tumor-Targeted Oxidative Chemotherapy. Kumar A, Chelvam V, Sakkarapalayam M, Li G, Sanchez-Cruz P, Piñero NS, Low PS, Alegria AE. Open J Med Chem. 6(1):1-17 (2016).

  48. Substrate-Triggered Exosite Binding: Synergistic Dendrimer/Folic Acid Action for Achieving Specific, Tight-Binding to Folate Binding Protein. Chen J, van Dongen MA, Merzel RL, Dougherty CA, Orr BG, Kanduluru AK, Low PS, Marsh EN, Banaszak Holl MM. Biomacromolecules. 14;17(3):922-7 (2016).

  49. Intraoperative Molecular Diagnostic Imaging Can Identify Renal Cell Carcinoma. Guzzo TJ, Jiang J, Keating J, DeJesus E, Judy R, Nie S, Low P, Lal P, Singhal S. J Urol. 195(3):748-55 (2016).

  50. Intraoperative Molecular Imaging of Lung Adenocarcinoma Can Identify Residual Tumor Cells at the Surgical Margins. Keating JJ, Okusanya OT, De Jesus E, Judy R, Jiang J, Deshpande C, Nie S, Low P, Singhal S. Mol Imaging Biol. 18(2):209-18 (2016).

  51. Predicting Response to Therapy for Autoimmune and Inflammatory Diseases Using a Folate Receptor-Targeted Near Infrared Fluorescent Imaging. Kelderhouse L, Mahalingam S, Low PS. Mol Imaging Biol. 18(2):201-8 (2015).

  52. Quantification of tumor fluorescence during intraoperative optical cancer imaging. Judy RP, Keating JJ, DeJesus EM, Jiang JX, Okusanya OT, Nie S, Holt DE, Arlauckas SP, Low PS, Delikatny EJ, Singhal S. Sci Rep. 5:16208 (2015).

  53. Concurrent Detection of Cellular and Molecular Cancer Markers Using an Immunomagnetic Flow System. Huang W, Chang CL, Chan BD, Jalal SI, Matei DE, Low PS, Savran CA. Anal Chem. 87(20):10205-12 (2015).

  54. Biodistribution of Fracture-Targeted GSK3β Inhibitor-Loaded Micelles for Improved Fracture Healing. Low SA, Galliford CV, Yang J, Low PS, Kopeček J. Biomacromolecules. 16(10):3145-53 (2015).

  55. Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging. De Jesus E, Keating JJ, Kularatne SA, Jiang J, Judy R, Predina J, Nie S, Low P, Singhal S. Int J Mol Imaging. 2015:469047 (2015).

  56. Prediction of Response to Therapy for Autoimmune/Inflammatory Diseases Using an Activated Macrophage-Targeted Radioimaging Agent. Kelderhouse L, Robins, M, Rosenbalm K, Hoylman E, Mahalingam S, Low PS. Mol Pharm. 12(10):3547-55 (2015).

  57. The Optical Biopsy: A Novel Technique for Rapid Intraoperative Diagnosis of Primary Pulmonary Adenocarcinomas. Kennedy GT, Okusanya OT, Keating JJ, Heitjan DF, Deshpande C, Litzky LA, Albelda SM, Drebin JA, Nie S, Low PS, Singhal S. Ann Surg. 262(4):602-9 (2015).

  58. Fluorescence assay of the interaction between hemoglobin and the cytoplasmic domain of erythrocyte membrane band 3. Sega MF, Chu H, Christian JA, Low PS. Blood Cells Mol Dis. 55(3):266-71 (2015).

  59. Folate Receptor Expression on Murine and Human Adipose Tissue. Hansen MJ, Bandara NA, Low PS. Inflamm Res. 64(9):697-706. (2015).

  60. Antiinflammatory Activity of a Novel Folic Acid Targeted Conjugate of the mTOR Inhibitor Everolimus. Lu Y, Parker N, Kleindl PJ, Cross VA, Wollak K, Westrick E, Stinnette TW, Gehrke MA, Wang K, Santhapuram HK, You F, Hahn SJ, Vaughn JF, Klein PJ, Vlahov IR, Low PS, Leamon CP. Mol Med. 21(1):584-96. (2015).

  61. Selective Tumor Targeting of Microtubule Disrupters, Desacetyl Vinblastine Hydrazide and Tubulysin B, via Conjugation to a Cholecystokinin 2 Receptor Antagonist. Wayua C, Roy J, Putt KS, Low PS. Mol Pharm. 6;12(7):2477-83 (2015).

  62. Intraoperative molecular imaging can identify lung adenocarcinomas during pulmonary resection. Okusanya OT, DeJesus EM, Jiang JX, Judy RP, Venegas OG, Deshpande CG, Heitjan DF, Nie S, Low PS, Singhal S. J Thorac Cardiovasc Surg. 150(1):28-35.e1 (2015).

  63. Assessment of folate receptor-ß expression in human neoplastic tissues. Shen J, Putt KS, Visscher DW, Murphy L, Cohen C, Singhal S, Sandusky G, Feng Y, Dimitrov DS, Low PS. Oncotarget. 6(16):14700-9 (2015).

  64. Comparison of Nanoparticle Penetration into Solid Tumors and Sites of Inflammation: Studies Using Targeted and Non-Targeted Liposomes. Poh S, Chelvam V and Low PS.  Nanomedicine (Lond). 10(9):1439-49 (2015).

  65. Targeting of folate receptor-beta on acute myeloid leukemia blasts with chimeric antigen receptor expressing T-cells. Lynn RC, Poussin MA, Kalota A, Feng Y, Low PS, Dimitrov DS, and Powell DJ. Blood. 125(22):3466-76 (2015).

  66. DUPA Conjugation of a Cytotoxic Indenoisoquinoline Topoisomerase I Inhibitor for Selective Prostate Cancer Cell Targeting. Roy J, Nguyen TX, Kanduluru AK, Venkatesh C, Lv W, Reddy PV, Low PS, Cushman M. J Med Chem. 58(7):3094-103 (2015).

  67. Synthesis and evaluation of a ligand targeting the somatostatin-2 receptor for drug delivery to neuroendocrine cancers. Li G, Low PS. Bioorg Med Chem Lett 25:1792-8 (2015).

  68. Evaluation of a nonpeptidic ligand for imaging of cholecystokinin 2 receptor-expressing cancers.  Wayua C, Low PS. J Nucl Med. 56:113-9 (2015).

  69. Principles in the design of ligand-targeted cancer therapeutic and imaging agents. Srinivasarao M, Low PS. Nat Rev Drug Discov 14:203-19 (2015).

  70. Folate receptor-ß imaging using 99mTc-folate to explore distribution of polarized macrophage populations in human atherosclerotic plaque. Jager NA, Westra J, Golestani R, van Dam GM, Low PS, Tio RA, Slart RH, Boersma HH, Bijl M, Zeebregts CJ. J Nucl Med 55:1945-51 (2014).

  71. Molecular Imaging to Identify Tumor Recurrence Following Chemoradiation in a Hostile Surgical Environment. Okusanya OT, Deshpande C, Barbosa Jr EM, Aggarwal C, Simone II CB, Jiang J, Judy R, DeJesus E, Albelda S, Nie S, Low PS, and Singhal S. Mol Imaging 13:1-6 (2014).

  72. Dietary supplementation with docosahexanoic acid (DHA) increases red blood cell membrane flexibility in mice with sickle cell disease. Wandersee NJ, Maciaszek JL, Giger KM, Hanson MS, Zheng S, Guo Y, Mickelson B, Hillery CA, Lykotrafitis G, Low PS, Hogg N. Blood Cells Mol Dis. 54:183-8 (2014).

  73. Folate receptor-ß constitutes a marker for human proinflammatory monocytes. Shen J, Hilgenbrink AR, Xia W, Feng Y, Dimitrov DS, Lockwood MB, Amato RJ, Low PS. J Leukoc Biol 96:563-70 (2014).

  74. In vivo mouse fluorescence imaging for folate-targeted delivery and release kinetics. Tsai EH, Bentz BZ, Chelvam V, Gaind V, Webb KJ, Low PS. Biomed Opt Express 5(8):2662-78 (2014).

  75. In vivo optical imaging of folate receptor-ß in head and neck squamous cell carcinoma. Sun JY, Shen J, Thibodeaux J, Huang G, Wang Y, Gao J, Low PS, Dimitrov DS, Sumer BD.  Laryngoscope 124:E312-9 (2014).

  76. Folate receptor-ß in activated macrophages: Ligand binding and receptor recycling kinetics. Varghese B, Vlashi E, Xia W, Lopez W, Paulos C, Reddy J, Xu L, Low PS. Mol Pharm 11:3609-16 (2014).

  77. Evaluation of a cholecystokinin 2 receptor-targeted near infrared dye for fluorescence guided surgery of human cancers. Wayua C, Low P. Mol Pharm 11:468-76 (2014).

  78. The effect of receptor occupancy on folate receptor internalization. Bandara NA, Hansen MJ, Low PS. Mol Pharm 11:1007-13 (2014).

  79. Avidity Mechanism of Dendrimer-Folic Acid Conjugates. van Dongen M, Silpe J, Dougherty C, Kanduluru AK, Choi SK, Orr B, Low PS, Banaszak-Holl M. Mol Pharm 11:1696-706 (2014).

  80. Assessment of folate receptor expression and folate uptake in multicentric lymphomas in dogs.  Childress MO, Dhawan D, Leamon CP, Miller MA, Ramos-Vara JA, Naughton JF, Low PS, Knapp DW. Am J Vet Res 75:187-94. (2014).

  81. Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection.  Pandey RK, Jarvis GG, Low PS. Org Biomol Chem 12:1707-10 (2014).

  82. Guiding principles in the design of ligand-targeted nanomedicines. Wang B, Galliford CV, Low PS. Nanomedicine (Lond) 9:313-30 (2014).

  83. A Phase I/Ib study of folate immune (EC90 vaccine administered with GPI-0100 adjuvant followed by EC17) with interferon-α and interleukin-2 in patients with renal cell carcinoma. Amato R, Shetty AV, Lu JY, Ellis PR, Mohlere V, Carnahan N, Low PS. J Immunother 37:237-44 (2014).

  84. Use of folate-conjugated imaging agents to target alternatively activated macrophages in a murine model of asthma.  Shen J, Chelvam V, Cresswell G, Low PS. Mol Pharm 10:1918-27 (2013).

  85. Spinal muscular atrophy: from gene discovery to clinical trials.  Nurputra DK, Lai PS, Harahap NI, Morikawa S, Yamamoto T, Nishimura N, Kubo Y, Takeuchi A, Saito T, Takeshima Y, Tohyama Y, Tay SKh, Low PS, Saito K, Nishio H. Ann Hum Genet 77:435-63 (2013).

  86. Expression of functional folate receptors by human parathyroid cells. Weber CJ, Müller S, Safley SA, Gordon KB, Amancha P, Villinger F, Camp VM, Lipowska M, Sharma J, Müller C, Schibli R, Low PS, Leamon CP, Halkar RK. Surgery 154:1385-93 (2013).

  87. Effect of folate-targeted nanoparticle size on their rates of penetration into solid tumors. Vlashi E, Kelderhouse L, Sturgis J, Low PS. ACS Nano 7:8573-82. (2013).

  88. Label-free detection of Staphylococcus aureus captured on immutable ligand arrays. Adak AK, Boley JW, Lyvers DP, Chiu GT, Low PS, Reifenberger R, Wei A. ACS Appl Mater Interfaces Jul 5:6404-11. (2013).

  89. Development of tumor-targeted near infrared probes for fluorescence guided surgery. Kelderhouse L, Chelvam V, Wayua C, Mahalingam S, Poh S, Kularatne S, Low PS. Bioconjug Chem 24:1075-80. (2013).

  90. A phase I study of folate immune therapy (EC90 vaccine administered with GPI-0100 adjuvant followed by EC17) in patients with renal cell carcinoma. Amato RJ, Shetty A, Lu Y, Ellis R, Low PS. J Immunother. 36(4):268-75 (2013).

  91. Comparative analysis of folate derived PET Imaging Agents with [(18)F]-2-fluoro-2-deoxy-d-glucose using a rodent inflammatory paw model. Kularatne SA, Bélanger MJ, Meng X, Connolly BM, Vanko A, Suresch DL, Guenther I, Wang S, Low PS, McQuade P, Trotter DG. Mol Pharm 5:3103-11.(2013).

  92. A bacterial phosphatase- like enzyme of the malaria parasite Plasmodium falciparumpossesses tyrosine phosphatase activity and is implicated in the regulation of band 3     dynamics during parasite invasion. Fernandez-Pol S, Slouka Z, Bhattacharjee S, Fedotova Y, Freed S, An X, Holder AA, Campanella E, Low PS, Mohandas N, Haldar K. Eukaryot Cell12:1179-91.(2013).

  93. Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma. Grapp M, Wrede A, Schweuzer M, Huiwel S, Galla HJ, Snaidero N, Simons M, Buckers J, Low PS, Urlaub H, Gartner J, Steinfield R. Nat Commun. 4:2123. (2013).

  94. Small animal optical diffusion tomography with targeted fluorescence. Gaind V, Tsai HR, Webb KJ, Chelvam V, Low PS. J Opt Soc Am A Opt Image Sci Vis 30:1146-54.(2013)

  95. Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis. Gent YY, Weijers K, Molthoff CF, Windhorst AD, Huisman MC, Smith DE, Kularatne SA, Jansen G, Low PS, Lammertsma AA, van der Laken CJ. Arthritis Res Ther. 15:R37. (2013).

  96. Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents. Cagle PT, Zhai QJ, Murphy L, Low PS. Arch Pathol Lab Med. 137:241-4. (2013).

  97. Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte membrane.  Stefanovic M, Puchulu-Campanella E, Kodippili G, Low PS. Biochem J 449:143-50 (2013).

  98. Changes in the properties of normal human red blood cells during in vivo aging.  Franco RS, Puchulu-Campanella ME, Barber LA, Palascak MB, Joiner CH, Low PS, Cohen RM.  Am J Hematol 88:44-51 (2013).

  99. Identification of the components of a glycolytic enzyme metabolon on the human red blood cell membrane. Puchulu-Campanella E, Chu H, Anstee DJ, Tao WA, Low PS. J Biol Chem 288:848-58 (2013).

  100. Targeting folate receptors to treat invasive urinary bladder cancer. Dhawan D, Ramos-Vara JA, Naughton JF, Cheng L, Low PS, Rothenbuhler R, Leamon CP, Parker N, Klein PJ, Vlahov IR, Reddy JA, Koch M, Murphy L, Fourez LM, Stewart JC, Knapp DW. Cancer Res 73:875-84. (2013).

  101. Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes. Kodippili GC, Spector J, Hale J, Giger K, Hughes MR, McNagny KM, Birkenmeier C, Peters L, Ritchie K, Low PS. J Biol Chem 287:4129-38. (2012).

  102. New antimalarial indolone-N-oxides, generating radical species, destabilize the host cell membrane at early stages of Plasmodium falciparum growth: role of band 3 tyrosine phosphorylation. Pantaleo A, Ferru E, Vono R, Giribaldi G, Lobina O, Nepveu F, Ibrahim H, Nallet, JP, Carta F, Mannu F, Pippia P, Campanella, E, Low PS, Turrini F. Free Radic Biol Med., 52:527-36. (2012).

  103. Identification of contact sites between ankyrin and band 3 in the human erythrocyte membrane. Grey JL, Kodippili GC, Simon K, Low PS.  Biochemistry 51:6838-46. (2012).

  104. Imaging sites of infection using a 99mTc-labeled folate conjugate targeted to folate receptor positive macrophages. Henne WA, Rothenbuhler R, Ayala-Lopez W, Xia W, Varghese B, Low PS. Mol Pharm 9:1435-40 (2012).

  105. Identification of cytoskeletal elements that enclose the ATP pools that fuels the human red blood cell membrane cation pumps. Chu H, Puchulu-Campanella E, Galan JA, Tao WA, Low PS, Hoffman JF. Proc Natl Acad Sci 109:12794-9 (2012).

  106. A folate receptor-α-specific ligand that targets cancer tissue and not sites of inflammation.  Vaitilingam B, Chelvam V, Kularatne SA, Poh S, Ayala-Lopez W, Low PS. J Nucl Med 53:1127 (2012).

  107. Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents. Cagle PT, Zhai Q, Murphy L, Low PS. Arch Pathol Lab Med 10:5858 (2012).

  108. Targeted folate receptor ß fluorescence imaging as a measure of inflammation to estimate vulnerability within human atherosclerotic carotid plaque. Jager NA, Westra J, van Dam GM, Teteloshvili N, Tio RA, Breek JC, Slart RH, Boersma H, Low PS, Bijl M, Zeebregts CJ. J Nucl Med 53:1222-9 (2012).

  109. LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy. Johnson EO, Chang KH, Ghosh S, Venkatesh C, Giger K, Low PS, Shah K. J Cell Sci 125:1204-16 (2012).

  110. Interaction of deoxyhemoglobin with the cytoplasmic domain of murine erythrocyte band 3. Sega M, Chu H, Christian J, Low P.S. Biochemistry 51:3264-72 (2012).

  111. Label-free detection of a bacterial pathogen using an immobilized siderophore, deferoxamine. Kim Y, Lyvers DP, Wei A, Reifenberger RG, Low PS. Lab Chip 12:971-6 (2012).

  112. Folate-linked drugs for the treatment of cancer and inflammatory diseases. Yang J, Vlashi E, Low P. Subcell Biochem 56:163-79 (2012).

  113. Analysis of the mobilities of band 3 populations associated with the ankyrin and junctional complexes in intact murine erythrocytes. Kodippili GC, Spector J, Hale J, Giger K, Hughes MR, McNagny KM, Birkenmeier C, Peters L, Ritchie K, Low PS. J Biol Chem 287:4129-38 (2012).

  114. Synthesis and activity of folate conjugated didemnin B for potential treatment of inflammatory diseases. Henne WA, Kularatne SA, Ayala-López W, Doorneweerd DD, Stinnette TW, Lu Y, Low PS. Bioorg Med Chem Lett 22:709-12 (2012).

  115. Characterization of in vivo disulfide-reduction mediated drug release in mouse kidneys. Yang JJ, Kularatne S, Chen X, Low PS, Wang E. Mol Pharm 9:310-7 (2012).

  116. The effect of chemotherapy on expression of folate receptor-alpha  in ovarian cancer. Crane LM, Arts HJ, Van Oosten M, Low PS, van der Zee AG, van Dam GM, Bart J. Cellular Oncol 35:9-18 (2012).

  117. Folate receptor-α expression in resectable hepatic colorectal cancer metastases: patterns and significance.  D’Angelica MD, Ammor J, Gonen M, Klimstra DS, Low PS, Murphy L, Weiser MR, Paty PB, Fong Y, DeMatteo RP, Allen P, Jarnagin WR, Shia J. Modern Pathol 9:1221-8 (2011).

  118. A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity.  Feng Y, Shen J, Streaker ED, Lockwood M, Zhu Z, Low PS, Dimitrov DS. Arthritis Res Ther 13:R59 (2011).

  119. Single-cell electrical lysis of erythrocytes detects deficiencies in the cytoskeletal protein network. Bao N, Kodippili GC, Giger KM, Fowler VM, Low PS, Lu C. Lab Chip 11(18):3053-6 (2011).

  120. Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate. Lu Y, Stinnette TW, Westrick E, Klein PJ, Gehrke MA, Cross VA, Vlahov IR, Low PS, Leamon CP. Arthritis Res Ther 13:R56 (2011).

  121. Intraoperative Tumor-Specific Fluorescent Imaging in Ovarian Cancer by Folate Receptor-α Targeting: First In-Human Results. van Dam GM, Themelis G, Crane LMA, Harlaar NJ, Pleijhuis RG, Kelder W, Sarantopoulos A, de Jong JS, Arts HJG, van der Zee AGJ, Bart J, Low PS, Ntziachristos V. Nat Med 17: 1315-19 (2011).

  122. Regulation of Membrane-Cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3. Ferru E, Giger K, Pantaleo A, Campanella E, Grey J, Ritchie K, Vono R, Turrini F, Low PS. Blood 117: 5998-06 (2011).

  123. Bishydrazide Glycoconjugates for Lectin Recognition and Capture of Bacterial Pathogens. Adak AK, Leonov AP, Ding N, Thundimadathil J, Kularatne S, Low PS, Wei A. Bioconjug Chem 21:2065-75 (2010).

  124. Synthesis and Biological Analysis of Prostate-specific Membrane Antigen (PSMA)-Targeted Anti-Cancer Prodrugs. Kularatne SA Venkatesh C, Santhapuram HR, Wang K, Vaitilingam B, Henne WA, Low PS. J. Med. Chem 53:7767-77 (2010).

  125. Peroxiredoxin-2 Expression is increased in β-thalassemic Mouse Red Cells but is displaced from the Membrane as a Marker of Oxidative Stress. Matte A, Low PS, Turrini F, Bertoldi M, Campanella ME, Spano D, Pantaleo A, Siciliano A, De Franceschi L. Free Radic Biol Med 49:457-466 (2010).

  126. Erythrocyte Adducin: A Structural Regulator of the Red Blood Cell Membrane. Franco T, Low PS. Transfus. Clin. Bio. 17:87-94 (2010).

  127. Folate-Targeted Therapies for Cancer. Xia W, Low PS.  J. Med. Chem 53:6811-24 (2010)

  128. Selective Capture and Identification of Pathogenic Bacteria Using an Immobilized Siderophore. Doorneweerd DD, Henne WA, Reifenberger RG, Low PS. Langmuir 26:15424-9 (2010).

  129. Analysis of the Kinetics of Band 3 Diffusion in Human Erythroblasts during Assembly of the Erythrocyte Membrane Skeleton. Kodippili GC, Spector J, Kang GE, Liu H, Wickrema A, Ritchie K, Low PS. Br J Haematol 150:592-600 (2010).

  130. Deep-tissue Imaging of Intramolecular Fluorescence Resonance Energy-transfer Parameters. Gaind V, Kularatne S, Low PS, Webb KJ. Opt Lett 35:1314-6 (2010).

  131. Imaging of Atherosclerosis in Apoliprotein E Knockout Mice: Targeting of a Folate-Conjugated Radiopharmaceutical to Activated Macrophages. Ayala-Lopez W, Xia W, Varghese B, Low PS. J Nucl Med 51:768-74 (2010).

  132. Targeting of nanoparticles: folate receptor. Kularatne SA, Low PS. Methods Mol Biol 624:249-65 (2010).

  133. Evaluation of Band 3 Diffusion and Compartment Size by Single Particle Tracking. Low PS, Spector J, Sullivan C, Labotka R, Ritchie K, Kodippili GC. Clinical Biochemistry 42:1852 (2009).

  134. Strategy to Prevent Drug-related Hypersensitivity in Folate-targeted Hapten Immunotherapy of Cancer. Lu Y, Klein PJ, Westrick E, Zu LC, Santhapuram HK, Bloomfield A, Howard SJ, Vianov IR, Ellis PR, Low PS, Leamon CP. AAPS J 11:628-38 (2009)

  135. Real Time, Noninvasive Imaging and Quantitation of the Accumulation of Ligand-targeted Drugs into Receptor-expressing Solid Tumors. Viashi E, Sturgis JE, Thomas M, Low PS. Mol. Pharm 6:1868-75 (2009).

  136. Role of Band 3 in Regulating Metabolic Flux of Red Blood Cells. Lewis IA, Campanella ME, Markley JL, Low PS. Proc Natl Acad Sci U.S.A. 106:1851-20 (2009).

  137. Band 3 Catalyzes Sickle Hemoglobin Polymerization. Rotter MA, Chu H, Low PS, Ferrone FA. Biophys Chem 146:55-9 (2010).

  138. Functional Folate Receptor Alpha is elevated in the Blood of Ovarian Cancer Patients. Basal E, Eghbali-Fatourechi GZ, Kalli KR, Hartmann LC, Goodman KM, Goode EL, Kamen BA, Low PS, Knutson KL. PLoS One. 4:e6292 (2009).

  139. Expression of the folate receptor genes FOLR1 and FOLR3 differentiates ovarian carcinoma from breast carcinoma and malignant mesothelioma in serous effusions. Yuan, Y, Nymoen DA, Dong HP, Bjorang O, Shih IM, Low PS, Trope CG, Davidson B.  Hum. Pathol 40:1453-60 (2009).

  140. Ligand-Targeted Delivery of Small Interfering RNAs to Malignant Cells and Tissues. Thomas M, Kularatne SA, Qi L, Kleindl P, Leamon CP, Hansen MJ, Low PS. Ann. N.Y. Acad. Sci 1175:32–9 (2009).

  141. Where Spectrin Snuggles with Ankyrin. Low PS. Blood 113:5372-5373 (2009).

  142. Design, Synthesis, and Pre-clinical Evaluation of Prostate-Specific Membrane Antigen (PSMA)-Targeted Tc-99m-Radioimaging Agents. Kularatne SA, Zhou ZG, Yang J, Post CB, Low PS. Mol Pharm 6:790-800 (2009).

  143. Assessment of Disease Activity to Rheumatoid Arthritis Using a Novel Folate Targeted Radiopharmaceutical FolatescanTM. Matteson EL, Lowe VJ, Prendergast FG, Crowson DS, Moder KG, Morgenstern DE, Messmann RA, Low PS. Clin Exp Rheumatol 27:253-259 (2009).

  144. Folate-Targeted Therapeutic and Imaging Agents for Cancer. Low PS, Kularatne SA. Curr Opin Chem Biol 13:256-62 (2009).

  145. Adducin forms a Bridge between the Erythrocyte Membrane and its Cytoskeleton and Regulates Membrane Cohesion. Anong WA, Franco T, Chu H, Weis TL, Devlin EE, Bodine DM, An X, Narla M, Low PS. Blood 114:1904-12 (2009).

  146. Prostate-Specific Membrane Antigen (PSMA)-Targeted Imaging and Therapy of Prostate Cancer Using a PSMA Inhibitor as a Homing Ligand. Kularatne SA, Wang K, Santhapuram HKR, Low PS. Mol Pharm 6, 780-89 (2009).

  147. Imaging of the Diffusion of Single Band 3 Molecules on Normal and Mutant Erythrocytes.  Kodippili GC, Spector J, Sullivan C, Kuypers FA, Labotka R, Gallagher PG, Ritchie K, Low PS. Blood 113:6237-45 (2009).

  148. Folate-Targeted Hapten Immunotherapy of Adjuvant-Induced Arthritis: Comparison of Hapten Potencies. Yi YS, Ayala-Lopez W, Kularatne SA, Low PS. Mol Pharm 6:1228-36 (2009).

  149. A Functional Folate Receptor is Induced during Macrophage Activation and can be used to Target Drugs to Activated Macrophages. Xia W, Hilgenbrink AR, Matteson EL, Lockwood MB, Cheng JX, Low PS. Blood 113:438-46 (2009).

  150. Fast Release of Lipophilic Agents from Circulating PEG-PDLLA Micelles Revealed by in Vivo Forster Resonance Energy Transfer Imaging. Chen H, Kim S, He W, Wang H, Low PS, Park K, Cheng JX. Langmuir 24:5213-17 (2008).

  151. A Role for the Proton-coupled Folate Transporter (PCFT - SLC46A1) in Folate Receptor-mediated Endocytosis. Zhao R, Yanhua SHM, Wang Y, Campanella E, Low PS, Goldman ID.  J Biol Chem 284:4267-74 (2008).

  152. Quantitation of Circulating Tumor Cells in Blood Samples from Ovarian and Prostate Cancer Patients Using Tumor-specific Fluorescent ligands.  He W, Kularatne SA, Kalli KR, Prendergast FG, Amato RJ, Klee GG, Hartman LC, Low PS. Int J Cancer 123:1968-73 (2008).

  153. Two-photon Luminescence Imaging of bacillus Spores using Peptide-functionalized Gold Nanorods. He, W, Henne WA, Wei Q, Zhao Y, Doorneweerd DD, Cheng JX, Low PS, Wei A. Nano Res 1:450-56 (2008).

  154. Low-dose Radiation Potentiates the Therapetic Efficacy of Folate Receptor-targeted Hapten Therapy. Sega EI, Lu Y, Ringor M, Leamon CP, Low PS. Int J Radiat Oncol Biol Phys 71:559-66 (2008).

  155. Characterization of Glycolytic Enzyme Interactions with Murine Erythrocyte Membranes in Wild-type and Membrane Protein Knockout Mice. Campanella ME, Chu H, Wandersee NJ, Peters LL, Mohandas N, Gilligan DM, Low PS.  Blood 112:3900-06 (2008).

  156. Osteopontin Regulates Actin Cytoskeleton and Contributes to Cell Proliferation in Primary Erythroblasts. Kang JA, Zhou Y, Weis TL, Liu H, Ulaszek J, Satgurunathan N, Zhou L, van Besien K, Crispino J, Verma A, Low PS, Wickrema A. J Biol Chem 283:6997-7006 (2008).

  157. Receptor-mediated Delivery of siRNAs by Tethered Nucleic Acid Base-paired Interactions.  Zhang K, Wang Q, Xie Y, Mor G, Sega E, Low PS, Huang Y. RNA 14:577-83 (2008).

  158. Immunohistochemical Expression of Folate Receptor Alpha in Colorectal Carcinoma:  Patterns and Biological Significance. Shia J, Klimstra DS, Nitzkorski JR, Low PS, Gonen M, Landmann R, Weiser MR, Franklin WA, Prendergast FG, Murphy L, Tang LH, Temple L, Guillem JG, Wong WD, Paty PB. Hum. Pathol 39:498-505 (2008).

  159. Folate Receptor Alpha as a Tumor Target in Epithelial Ovarian Cancer. Kalli KR, Oberg AL, Keeney GL, Christianson TJ, Low PS, Knutson KL, Hartmann LC. Gynecol Oncol 108:619-26 (2008).

  160. Tumor Detection using Folate Receptor-targeted Imaging Agents. Sega EI,Low PS.  Cancer Metastasis Rev 27:655–64 (2008).

  161. Cholesterol Level Regulates Endosome Motility via Rab Proteins. Chen H, Yang J, Low PS, Cheng JX. Biophys J 94:1508-20 (2008).

  162. Characterization of the Deoxyhemoglobin Binding Site on Human Erythrocyte Band 3: Implications for O2 Regulation of Erythrocyte Properties. Chu H, Breite A, Ciraolo P, Franco RS, Low PS. Blood 111:932-8 (2008).

  163. Discovery and Development of Folic-Acid-Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases. Low PS, Henne WA, Doorneweerd DD. Acc Chem Res 41:120-29 (2008).

  164. Immunomagnetic Diffractometry for Detection of Diagnostic Serum Markers. Acharya G, Chang CL, Doorneweerd DD, Vlashi E, Henne WA, Hartmann LC, Low PS, Savran CA. J Am Chem Soc 129:15824-29 (2007).

  165. The Optimal Strategy for Drug Targeting. Low PS. Mol. Pharm 4:629-30 (2007).

  166. Label-free Optical Detection of Anthrax-Causing Spores. Acharya G, Doorneweerd DD, Chang CL, Henne WA, Low PS, Savran CA. J Am Chem Soc 129:732-33 (2007).

  167. Characterization of the pH of Folate Receptor-containing Endosomes and the Rate of Hydrolysis of Internalized Acid-labile Folate-drug Conjugates. Yang J, Chen H, Vlahov IR, Cheng JX, Low PS. J Pharmacol Exp Ther 321:462-68 (2007).

  168. Folate Receptor Overexpression is Associated with Poor Outcome in Breast Cancer. Hartmann LC, Keeney GL, Lingle WL, Christianson TJ, Varghese B, Hillman D, Oberg AL, Low PS. Int J Cancer 121:938-42 (2007).

  169. An 11-amino Acid Beta-hairpin Loop in the Cytoplasmic Domain of Band 3 is Responsible for Ankyrin Binding in Mouse Erythrocytes. Stefanovic M, Markham NO, Parry EM, Garrett-Beal LJ, Cline AP, Gallagher PG, Low PS, Bodine DM. Proc Natl Acad Sci USA 104:13972-77 (2007).

  170. Folate-targeted Dinitrophenyl Hapten Immunotherapy: Effect of Linker Chemistry on Antitumor Activity and Allergic Potential. Lu Y, You F, Vlahov I, Westrick E, Fan M, Low PS, Leamon CP. Mol Pharm 4:695-706 (2007).

  171. Depletion of Folate-Receptor-Positive Macrophages Leads to Alleviation of Symptoms and Prolonged Survival in Two Murine Models of Systemic Lupus Erythematosus. Varghese B, Haase N, Low PS. Mol Pharm 4:679-85 (2007).

  172. In Vivo Quantitation of Rare Circulating Tumor Cells by Multiphoton Intravital Flow Cytometry. He W, Wang H, Hartmann LC, Cheng JX, Low PS. Proc Natl Acad Sci USA 104:11760-65 (2007).

  173. Preclinical Pharmacokinetics, Tissue Distribution, and Antitumor Activity of a Folate-hapten Conjugate-targeted Immunotherapy in Hapten-immunized Mice. Lu Y, Xu LC, Parker N, Westrick E, Reddy JA, Vetzel M, Low PS, Leamon CP. Mol Cancer Ther 5:3258-67 (2006).

  174. Rate of Rupture and Reattachment of the Band 3-Ankyrin Bridge in the Human Erythrocyte Membrane. Anong WA, Weis TL, Low PS. J. Biol. Chem. 281:22360-66 (2006).

  175. Synthesis and activity of a folate peptide camptothecin prodrug. Henne WA, Doorneweerd DD, Hilgenbrink AR, Kularatne SA, Low PS. Bioorg Med Chem Lett 16:5350-55 (2006).

  176. T-cell Immunity to the Folate Receptor Alpha is Prevalent in Women with Breast or Ovarian Cancer. Knutson KL, Krco CJ, Erskine CL, Goodman K, Kelemen LE, Wettstein PJ, Low PS, Hartmann LC, Kalli KR. J. Clin. Oncol. 24:4254-61 (2006).

  177. Evaluation of Disulfide Reduction during Receptor-mediated Endocytosis by using FRET Imaging. Yang J, Chen H, Vlahov IR, Cheng JX, Low PS. Proc. Natl. Acad. Sci. USA. 103:13872-77 (2006).

  178. Mapping of Glycolytic Enzyme-binding Sites on Human Erythrocyte Band 3. Chu H, Low PS. Biochem. J. 400:143-51 (2006).

  179. Detection of Folate Binding Protein with Enhanced Sensitivity using a Functionalized Quartz Crystal Microbalance Sensor. Henne WA, Doorneweerd DD, Lee J, Low PS, Savran C. Anal. Chem. 78:4880-84 (2006).

  180. Folate-targeted Immunotherapy Effectively Treats Established Adjuvant and Collagen-induced Arthritis. Paulos CM, Varghese B, Widmer R, Breur GJ, Vlashi E,  Low PS.  Arthritis Res Ther 8:R77 (2006).

  181. Detection of Bacillus Subtilis Spores using Peptide-functionalized Cantilever Arrays. Dhayal B, Henne WA, Doorneweerd DD, Reifenberger RG, Low PS. J. Am. Chem. Soc. 128:3716-21 (2006).

  182. Erythrocyte Adhesion is Modified by Alterations in Cellular Tonicity and Volume. Wandersee NJ, Punzalan RC, Rettig MP, Kennedy MD, Pajewski NM, Sabina RL, Scott JP, Low PS, Hillery CA.  Br J Haematol 131:366-77 (2005).

  183. In vitro and in vivo Two-Photon Luminescence Imaging of Single Gold Nanorods. Wang H, Huff TB, Zweifel DA, He W, Low PS, Wei A, Cheng JX. Proc. Natl. Acad. Sci. U.S.A. 102:15752-56 (2005)

  184. Folate Receptor-mediated Drug Targeting:  From Therapeutics to Diagnostics. Hilgenbrink AR, Low PS. J. Pharmaceutical Sciences 94:2135-46 (2005).

  185. Increased Uptake of Folate Conjugates by Activated Macrophages in Experimental Hyperlipidemia. Antohe F, Radulescu L, Puchianu E, Kennedy MD, Low PS, Simionescu M. Cell Tissue Res. 320:277-85 (2005).

  186. Folate Receptor-targeted Immunotherapy:  Induction of Humoral and Cellular Immunity against Hapten-Decorated Cancer Cells. Lu Y, Sega E, Low PS. Int. J. Cancer 116:710-19 (2005).

  187. Effector-induced Syk-mediated Phosphorylation in Human Erythrocytes. Clari G, Bordin L, Ion-Popa F, Brunati AM, Low PS. Biochim. Biophys. Acta 1745:20-28 (2005).

  188. Statistical Approach for Detection and Localization of a Fluorescing Mouse Tumor in Intralipid. Milstein AB, Kennedy MD, Low PS, Bouman CA, Webb KJ. Appl. Opt. 44:2300-10 (2005).

  189. The N-terminal 11 Amino Acids of Human Erythrocyte Band 3 are Critical for Aldolase Binding and Protein Phosphorylation:  Implications for Band 3 Function. Perrotta S, Borriello A, Scaloni A, De Franceschi L, Brunati AM,  Turrini F, Nigro V, del Giudice EM, Nobili B, Conte ML, Rossi F, Iolascon A, Donella-Deana A, Zappia V, Poggi V, Anong W, Low PS, Narla M, Ragione FD. Blood 106:4359-66 (2005).

  190. Folate Receptor Expression in Carcinomas and Normal Tissues Determined by a Quantitative Radioligand Binding Assay. Parker N, Turk MJ, Westrick E, Lewis JD, Low PS, Leamon CP.  Analytical Biochem. 338:284-93 (2005).

  191. Receptor-mediated Drug Delivery. Leamon CP, Low PS.  Drug Delivery: Principles and Applications pp. 167-187. (2005). (eds. B. Wang, T.J. Siahaan and R. Soltero.) John Wiley & Sons, Inc. Hoboken, NJ, USA.

  192. Assembly and Regulation of a Glycolytic Enzyme Complex on the Human Erythrocyte Membrane. Campanella ME, Chu H, Low PS.  Proc. Natl. Acad. Sci. 102:2402-7 (2005).

  193. Folate Receptor Mediated Targeting of Liposomal Drugs to Cancer Cells. Stephenson SM, Low PS, Lee RJ.  Methods in Enzymology 387:33-50 (2004)

  194. Ligand Binding and Kinetics of Folate Receptor Recycling in Vivo:  Impact on Receptor-Mediated Drug Delivery. Paulos CM, Reddy JA, Leamon CP, Turk MJ, Low PS. Mol. Pharmacol. 66:1406-14 (2004).

  195. Modulation of Red Cell Glycolysis:  Interactions between Vertebrate Hemoglobins and Cytoplasmic Domains of Band 3 Red Cell Membrane Proteins. Weber RE, Voelter W, Fago A, Echner H, Campanella E, Low PS.  Am. J. Physiol. Regul. Integr. Comp. Physiol. 287:R454-64 (2004).

  196. Folate-Conjugated Liposomes Preferentially Target Macrophages Associated with Ovarian Carcinoma. Turk MJ, Waters DJ, Low PS. Cancer Lett. 213:165-72 (2004).

  197. Folate Receptor-Mediated Targeting of Therapeutic and Imaging Agents to Activated Macrophages in Rheumatoid Arthritis. Paulos CM, Turk MJ, Breur GJ, Low PS. Adv. Drug Deliv. Rev. 56:1205-17 (2004).

  198. Folate Receptor-Targeted Immunotherapy of Cancer: Mechanism and Therapeutic Potential. Lu Y, Sega E, Leamon CP, Low PS. Adv. Drug Deliv. Rev. 56:1161-76 (2004).

  199. Folate Receptor-Targeted Drugs for Cancer and Inflammatory Diseases. Low PS, Antony P.  Adv. Drug Deliv. Rev. 56:1055-58 (2004)

  200. Uptake and Trafficking of Fluorescent Conjugates of Folic Acid in the Intact Kidney Using Intra-Vital 2-Photon Microscopy. Sandoval RM, Kennedy MD, Low PS, Molitoris BA.  Am. J. Physiol. Cell Physiol. 287:C517-26 (2004).

  201. Erythrocyte detergent-resistant membrane proteins: their characterization and selective uptake during malarial infection. Murphy SC, Samuel BU, Harrison T, Speicher, KD, Speicher DW, Reid ME, Prohaska R, Low PS, Tanner MJ, Mohandas N, Haldar K. Blood 103:1920-28 (2004).

  202. Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as Potential Folate-receptor-targeted PET Radiopharmaceuticals. Mathias CJ, Lewis MR, Reichert DE, Laforest R, Sharp TL, Lewis JS, Yang ZF, Waters DJ, Snyder PW, Low PS, Welch MJ, Green MA. Nuclear Med. and Biol. 30:725-31 (2003).

  203. Altered Erythrocyte Endothelial Adherence and Membrane Phospholipid Asymmetry in Hereditary Hydrocytosis. Gallagher PG, Chang SH, Rettig MP, Neely JE, Hillery CA, Smith BD, Low PS. Blood 101:4625-27 (2003).

  204. Evaluation of Folate Conjugate Uptake and Transport by the Choroid Plexus of Mice. Kennedy MD, Jallad KN, Lu J, Low PS, Ben–Amotz D. Pharm. Res. 20:714-19(2003).

  205. Optical Imaging of Metastatic Tumors Using a Folate-Targeted Fluorescent Probe. Kennedy MD, Jallad KN, Thompson DH, Ben-Amotz D, Low PS. J. Biomed. Optics 8:636-41 (2003).

  206. Immunotherapy of Folate Receptor-Expressing Tumors: Review of Recent Advances and Future Prospects. Lu J, Low PS. J. Controlled Release 91:17-29 (2003).

  207. Targeted Immunotherapy of Cancer:  Development of Antibody-induced Cellular Immunity. Lu Y, Low PS. J. Pharmacy and Pharmacology 55:163-67, 2003.

  208. Identification of a Critical Ankyrin Binding Loop on the Cytoplasmic Domain of Erythrocyte Membrane Band 3 by Crystal Structure Analysis and Site-directed Mutagenesis. Chang SH, Low PS.  J. Biol. Chem. 278:6879-84 (2003).

  209. An Osmotically Induced Cytosolic Ca2+ Transient Activates Calcineurin Signaling to Mediate Ion Homeostasis and Salt Tolerance of Saccharomyces cerevisiae. Matsumoto TK, Ellsmore AJ, Cessna SG, Low PS, Pardo JM, Bressan RA, Hasegawa PM. J. Biol. Chem. 277:33075-80 (2002).

  210. Synthesis and Evaluation of 99mTc(CO)3-DTPA-Folate as a Folate-Receptor-Targeted Radiopharmaceutical. Trump DP, Mathias CJ, Yang ZF, Low PS, Marmion MA, Green MA. Nucl. Med. Biol. 29:569-73 (2002).

  211. Phorbol Ester Stimulates a Protein Kinase C-mediated Agatoxin-TK-sensitive Calcium Permeability Pathway in Human Red Blood Cells. Andrews DA, Yang L, Low PS. Blood 100:3392-99 (2002).

  212. Protein Kinase C Activation Induces Phosphatidylserine Exposure on Red Blood Cells. de Jong K, Rettig MP, Low PS, Kuypers FA. Biochem. 41:12562-67 (2002).

  213. Heme Redox Properties of S-nitrosated Hemoglobin A and Hemoglobin S:  Implications for Interactions of Nitric Oxide with Normal and Sickle Red Blood Cells. Bonaventura C, Taboy CH, Low PS, Stevens RD, Lafon C, Crumbliss AL. J. Biol. Chem. 277:14557-63 (2002).

  214. Folate-targeted Imaging of Activated Macrophages in Rats with Adjuvant-Induced Arthritis. Turk MJ, Breur GJ, Widmer WR, Paulos CM, Xu LC, Grote LA, Low PS.  Arthritis & Rheumatism 46:1947-55 (2002).

  215. Folate-mediated Delivery of Macromolecular Anticancer Therapeutic Agents. Lu Y, Low PS. Adv. Drug Deliv. Rev. 54:675-93 (2002).

  216. Synthesis and Evaluation of Taxol-Folic Acid Conjugates as Targeted Antineoplastics. Lee JW, Lu JY, Low PS, Fuchs PL.  Bioorganic & Medicinal Chem. 10:2397-414 (2002).

  217. Headpiece Domain of Dematin is Required for the Stability of the Erythrocyte Membrane. Khanna R, Chang SH, Andrabi S, Azam M, Kim A, Rivera A, Brugnara C, Low PS, Liu SC, Chishti AH. Proc. Natl. Acad. Sci. 99:6637-42 (2002).

  218. Folate-targeting of Haptens to Cancer Cell Surfaces Mediates Immunotherapy of Syngeneic Murine Tumors. Lu Y, Low PS. Cancer Immunol. Immunother. 51:153-62 (2002).

  219. Characterization of a Novel pH-sensitive Peptide that Enhances Drug Release from Folate-targeted Liposomes at Endosomal pHs. Turk MJ, Reddy JA, Chmielewski JA, Low PS. Biochim. Biophys. Acta 1559:56-68 (2002).

  220. Analysis of Integral Membrane Protein Contributions to the Deformability and Stability of the Human Erythrocyte Membrane. Van Dort HM, Knowles DW, Chasis JA, Lee G, Narla N, Low PS. J. Biol. Chem. 276:46968-74 (2001).

  221. Activation of the Oxidative Burst in Aequorin-transformed Nicotiana tabacum cells is Mediated by Protein Kinase- and Anion Channel-dependent Release of Ca2+ from Internal Stores. Cessna SG, Low PS. Planta 214:126-34 (2001).

  222. Effect of pH on the Self-Association of Erythrocyte Band 3 In Situ. Rettig MP, Orendorff CJ, Campanella E, Low PS. Biochim. Biophys. Acta 1515:72-81 (2001).

  223. Characterization of the Reversible Conformational Equilibrium in the Cytoplasmic Domain of Human Erythrocyte Membrane Band 3. Zhou J, Low PS.  J. Biol. Chem. 76:38147-51 (2001).

  224. Retargeting of Viral Vectors to the Folate Receptor Endocytic Pathway. Reddy JA, Clapp DW, Low PS. J. Controlled Release 74:77-82 (2001).

  225. Regulation of the Glycophorin C-protein 4.1 Membrane-to-Skeleton Bridge and Evaluation of Its Contribution to Erythrocyte Membrane Stability. Chang SH, Low PS. J. Biol. Chem. 276:22223-30 (2001).

  226. Measurement of Stress-induced Ca2+ Pulses in Single Aequorin-transformed Tobacco Cells. Cessna SG, Messerli MA, Robinson KR, Low PS. Cell Calcium 30:151-6 (2001).

  227. An Apoplastic Ca2+ Sensor Regulates Internal Ca2++ Release in Aequorin-transformed Tobacco Cells. Cessna SG, Low PS. J. Biol. Chem. 276:10655-62 (2001).

  228. Involvement of Mitogen-activated Protein Kinase Activation in the Signal-transduction Pathways of the Soya Bean Oxidative Burst. Taylor AT, Kim J, Low PS. Biochem. J. 355:795-803 (2001).

  229. Localization of Mutations Leading to Altered Cell Shape and Anion Transport in the Crystal Structure of the Cytoplasmic Domain of Band 3. Low, P. S.; Zhang, D.; Bolin, J. T.  Blood Cells Mol. Dis. 27:81-84 (2001).

  230. Folate-mediated Targeting:  From Diagnostics to Drug and Gene Delivery. Leamon CP, Low PS. Drug Discovery Today 6:44-51 (2001).

  231. Synthesis of 99mTc-DTPA-Folate and Evaluation as a Folate-Receptor-Targeted Radiopharmaceutical. Mathias CJ, Hubers D, Low PS, Green MA. Bioconjugate Chem. 11:253-57 (2000).

  232. Plasmodium falciparum Histidine-rich Protein 1 Associates with the Band 3 Binding Domain of Ankyrin in the Infected Red Cell Membrane. Magowan C, Nunomura W, Waller K, Yeung J, Liang J, Van Dort H, Low PS, Coppel R. Biochim. Biophys. Acta 1502:461-70 (2000).

  233. Oxalic Acid, a Pathogenicity Factor for Sclerotinia sclerotiorum, Suppresses the Plant Oxidative Burst of the Host Plant. Cessna SG, Sears VE, Dickman MB, Low PS. Plant Cell 12:2191-99 (2000).

  234. Homologous and heterologous desensitization and synergy in pathways leading to the soybean oxidative burst. Chandra S, Cessna SG, Yahraus T, Devine R, Low PS. Planta 211:736-42 (2000).

  235. Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3. Zhang D, Kiyatkin A, Bolin J, Low PS. Blood 96:2925-33 (2000).

  236. Lysophosphatidic Acid Opens a Ca++ Channel in Human Erythrocytes. Yang L, Andrews DA, Low PS. Blood 95:2420-25 (2000).

  237. Enhanced Folate Receptor Mediated Gene Therapy Using a Novel pH-Sensitive Lipid Formulation. Reddy JA, Low PS. J. Controlled Release 64:27-37 (2000).

  238. Folate as a Targeting Device for Proteins Utilizing Folate Receptor-mediated Endocytosis.  Lee RJ, Low PS. Methods in Molecular Medicine (ed. G.E. Francis and Cristina Delgado), Humana Press. vol. 25, chapter 5, 69-76 (2000).

  239. Synthesis and Evaluation of folate-Bis (Thiosemicarbazone) and Folate-Cyclam Conjugates for Possible Use as Folate-Receptor-Targeted Copper Radiopharmaceuticals.  Ke CY, Mathias CJ, Yang ZF, Luo J, Low PS, Waters DJ, Green MA. J. Labelled Compounds and Radiopharmaceuticals 42:S821-23 (1999).

  240. Oligogalacturonic Acid and Chitosan Reduce Stomatal Aperture by Inducing the Evolution of Reactive Oxygen Species from Guard Cells of Tomato and Commelina communis. Lee S, Choi H, Suh S, Doo IS, Oh KY, Choi EJ, Taylor ATS, Low PS, Lee Y. Plant Phys.121:147‑52 (1999).

  241. Optimization of Folate-Conjugated Liposomal Vectors for Folate Receptor-Mediated Gene Therapy. Reddy JA, Dean D, Kennedy MD, Low PS. J. Pharmaceutical Sciences 88:1112-8 (1999).

  242. Folate-Targeted Enzyme Prodrug Cancer Therapy Utilizing Penicillin-V Amidase and a Doxorubicin Prodrug. Lu JY, Lowe DA, Kennedy MD, Low PS. J. Drug Targeting 7:43-53 (1999).

  243. Role of Red Blood Cells in Thrombosis. Andrews DA, Low PS. Current Opinion in Hematology 6:76-82 (1999).

  244. Expression and Functional Characterization of the ß-isoform of the Folate Receptor on CD34+ Cells. Reddy JA, Haneline LS, Srour EF, Antony AC, Clapp DW, Low PS. Blood 93:3940-48 (1999).

  245. Receptor-Mediated Targeting of 67Ga-Deferoxamine-Folate to Folate-Receptor-Positive Human KB Tumor Xenografts. Mathias CJ, Wang S, Low PS, Waters DJ, Green MA. Nuclear Medicine & Biology 26:23-25 (1999).

  246. South-East Asian Ovalocytic (SAO) Erythrocytes have a Cold Sensitive Cation Leak: Implications for in vitro Studies on Stored SAO Red Cells. Bruce LJ, Ring SM, Ridgwell K, Reardon DM, Seymour CA, Van Dort HM, Low PS, Tanner MJ. Biochim. Biophys. Acta 1416:258‑70 (1999).

  247. Riboflavin-mediated delivery of a macromolecule into cultured human cells. Holladay SR, Yang ZF, Kennedy MD, Leamon CP, Lee RJ, Jayamani M, Mason T, Low PS. Biochim. Biophys. Acta 1426:195-204 (1999).

  248. Evaluation of Biochemical Changes During In Vivo Erythrocyte Senescence in the Dog. Rettig M, Low PS, Gimm A, Narla M, Wang J, Christian JA. Blood 93:376-84 (1999).

  249. Characterization of the Hypertonically-Induced Tyrosine Phosphorylation of Erythrocyte Band 3. Minetti G, Seppi C, Ciana A, Balduini C, Low PS, Brovelli A. Biochem. J. 335:305-11 (1998).

  250. Folate-Mediated Targeting of Therapeutic and Imaging Agents to Cancers. Reddy JA, Low PS. Crit. Rev. Ther. Drug Carrier Systems 15:587-627 (1998).

  251. Diplasmenylcholine-Folate Liposomes: An Efficient Vehicle for Intracellular Delivery of Hydrophilic Compounds. Rui YJ, Wang S, Low PS, Thompson DH. J. Am. Chem. Soc. 120:11213-18 (1998).

  252. Hypo-osmotic Shock of Tobacco Cells Stimulates Ca2+ Fluxes Deriving First from External and then Internal Ca2+ Stores. Cessna SG, Chandra S, Low PS. J. Biol. Chem. 273:27286-91 (1998).

  253. How Old are Dense RBC?  The Dog's Tale. Christian JA, Wang J, Rettig M, Kiyatkina N, Low PS. Blood 92:2590-604 (1998).

  254. The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane. Chishti AH, Kim AC, Marfatia SM, Lutchman M, Hanspal M, Jindal H, Liu SC, Low PS, Rouleau GA, Mohandas N, Chasis JA, Conboy JG, Gascard P, Takakuwa Y, Huang SC, Benz EJ Jr, Bretscher A, Fehon RG, Gusella JF, Ramesh V, Solomon F, Marchesi VT, Tsukita S, Tsukita S, Arpin M, Louvard D, Tonks NK, Anderson JM, Fanning AS, Bryant PJ, Woods DF, Hoover KB. Trends Biochem. Sci. 23:281-82 (1998).

  255. Folate-mediated targeting of liposomal and viral vectors to cancer cells. Low PS, Reddy JA. Gene Therapy & Molecular Biology from Basic Mechanisms to Clinical Applications.  Gene Therapy Press.2:288-292 (1998).

  256. Indium-111-DTPA-Folate as a Potential Folate-Receptor-Targeted Radiopharmaceutical.  Mathias CJ, Wang S, Waters DJ, Turek JJ, Low PS, Green MA. J. Nuclear Medicine 39:1579-85 (1998).

  257. Purification of a glycoprotein elicitor of phytoalexin formation from Verticillium Dahliae. Davis DA, Low PS, Heinstein P. Physiological and Molecular Plant Pathology 52:259-73 (1998).

  258. The Effects of pH and Intraliposomal Buffer Strength on the Rate of Liposome Content Release and Intracellular Drug Delivery. Lee RJ, Wang S, Turk MJ, Low PS. Bioscience Reports 18:69-78 (1998).

  259. Systemin Potentiates the Oxidative Burst in Cultured Tomato Cells. Stennis MJ, Chandra S, Ryan CA, Low PS. Plant Physiol. 117:1031-6 (1998).

  260. Folate-Mediated Targeting of Antineoplastic Drugs, Imaging Agents, and Nucleic Acids to Cancer Cells. Wang S, Low PS. J. Controlled Release 53:39-48 (1998).

  261. Effect of Band 3 Subunit Equilibrium on the Kinetics and Affinity of Ankyrin Binding to Erythrocyte Membrane Vesicles. Van Dort HM, Moriyama R, Low PS. J. Biol. Chem. 273:14819-26 (1998).

  262. Biochemical Analysis of Potential Sites for Protein 4.1-Mediated Anchoring of the Spectrin-Actin Skeleton to the Erythrocyte Membrane. Workman RF, Low PS. J. Biol. Chem. 273:6171-6 (1998).

  263. Effect of Purification Protocol on the Functional Properties of Erythrocyte Membrane Protein 4.1. Workman RF, Low PS. Protein Expression and Purification 12:100-4 (1998).

  264. Folate-Targeted Liposomes for Drug Delivery. Lee RJ, Low PS. J. Liposome Research 7:455-66 (1997)

  265. Measurement of Ca2+ Fluxes During Elicitation of the Oxidative Burst in Aequorin-Transformed Tobacco Cells. Chandra S, Low PS. J. Biol. Chem. 272:28274-80 (1997).

  266. Intracellular Delivery of Peptides and Proteins. Low PS, Leamon CR. ACS Professional Reference Book, Controlled Drug Delivery, Challenges and Strategies, published by the American Chemical Society, p. 11-25 (1997).

  267. Phospholipase D Involvement in the Plant Oxidative Burst. Schroeder Taylor AT, Low PS. Biochem. and Biophys. Res. Comm. 237:10-15 (1997).

  268. Design and Synthesis of 111In-DTPA-Folate for Use as a Tumor-Targeted Radiopharmaceutical. Wang S, Luo J, Lantrip DA, Waters DJ, Mathias CJ, Green MA, Fuchs PL, Low PS. Bioconjugate Chemistry 8:673-9 (1997).

  269. Signal Transduction Pathways of the Plant Oxidative Burst. Low PS, Schroeder AT. Plant-Microbe Interactions Vol. 3, chap. 2, p. 35-52. (1997).

  270. Erythrocyte Signal Transduction Pathways and their Possible Functions. Minetti G, Low PS. Current Opinion in Hematology 4:116-21 (1997).

  271. Identification of  the Major Casein  Kinase I Phosphorylation Sites on Erythrocyte Band 3. Wang CC, Tao M, Wei T, Low PS. Blood 89:3019-24 (1997).

  272. Rapid Epitope Mapping. Low PS, Yuan J. Protein Protocols Handbook (ed. J. Walker) Humana Press, Inc., Totowa, N.J., p. 573-579 (1996).

  273. Riboflavin-enhanced Transport of Serum Albumin Across the Distal Pulmonary Epithelium. Wangensteen OD, Bartlett MM, James JK, Yang ZF, Low PS.  Pharmaceutical Research 13:1861-4 (1996).

  274. A Comparison of Methods for the Determination of the Oxidative Burst in Whole Plants. Schroeder AT, Martin G, Low PS. Biology of Plant-Microbe Interactions, (eds. Stacey G, Mullin B, and Gresshoff PM), International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, pp. 15-20 (1996)

  275. The Pto Kinase Mediates a Signaling Pathway Leading to the Oxidative Burst in Tomato. Chandra S, Martin GB, Low PS. Proc. Natl. Acad. Sci. USA 93:13393-97 (1996).

  276. Peptide Mediated Release of Folate-Targeted Liposome Contents from Endosomal Compartments. Vogel K, Wang S, Lee RJ, Chmielewski J, Low PS. J. Am. Chem. Soc. 118:1581-86 (1996).

  277. Measurement of Endosome pH following Folate Receptor-mediated Endocytosis. Lee RJ, Wang S, Low PS. Biochim. Biophys. Acta 1312:237-42 (1996).

  278. Prostaglandin E2 Stimulates a Ca2+-dependent K+ Channel in Human Erythrocytes and Alters Cell Volume and Filterability. Li Q, Jungmann V, Kiyatkin A, Low PS. J. Biol. Chem. 271:18651-56 (1996).

  279. Tumor-Selective Radiopharmaceutical Targeting via Receptor-Mediated Endocytosis of Gallium-67-Deferoxamine-Folate. Mathias CJ, Wang S, Lee RJ, Waters DJ, Low PS, Green MA. Journal of Nuclear Medicine 37:1003-8 (1996).

  280. Rapid site-directed mutagenesis by a method that selects for full length mutated DNA. Wang CC, Fernando LP, Low PS. Nucleic Acids Research 24:1378-79 (1996).

  281. The oxidative burst in plant defense:  Function and signal transduction. Low PS, Merida JR. Physiologia Plantarum 96:533-42 (1996).

  282. Activation of Phospholipase A by Plant Defense Elicitors. Chandra S, Heinstein PF, Low PS. Plant Physiol. 110:979-86 (1996).

  283. Synthesis, Purification, and Tumor Cell Uptake of 67Ga-Deferoxamine-Folate, a Potential Radiopharmaceutical for Tumor Imaging. Wang S, Lee RJ, Mathias CJ, Green MA, Low PS. Bioconjugate Chemistry 7:56-62 (1996).

  284. Plants and Human Neutrophil Oxidative Burst Complexes Contain Immunologically Related Proteins. Dwyer S, Legendre L, Heinstein PF, Low PS, Leto TL. Biochim. Biophys. Acta 1289:231-37 (1996).

  285. Methodologic considerations for the use of canine in vivo aged biotinylated erythrocytes to study RBC senescence. Christian JA, Rebar AH, Boon GD, Low PS. Experimental Hematology 24:82-8 (1996).

  286. Evidence for a Mechanically Induced Oxidative Burst. Yahraus T, Chandra S, Legendre L, Low PS. Plant Physiol. 109:1259-66 (1995).

  287. The Design of pH-dependent Amphipathic Helices to Trigger Cytoplasmic Delivery of Liposome Encapsulated Molecules. Vogel KM, Wang S, Low PS, Chmielewski JA. Peptides: Chemistry, Structure and Biology (ed. Kanmaya PTP, Hodges RS), ESCOM, Leiden, The Netherlands, 1995, pp. 371-372.

  288. Partial Characterization of the Cytoplasmic Domain of Human Kidney Band 3. Wang CC, Moriyama R, Lombardo CR, Low PS. J. Biol. Chem. 270:17892-7 (1995).

  289. Crystallization  and  Preliminary  X-ray Analysis of the Cytoplasmic Domain of Human Erythrocyte Band 3. Kiyatkin AB, Munshi S, Johnson JE, Low PS. PROTEINS: Structure, Function & Genetics 22:293-7 (1995).

  290. Vitamin-mediated delivery of proteins, antisense oligonucleotides and genes into living cells. Low PS. Restorative Neurology and Neuroscience 8:15 (1995).

  291. Role of Phosphorylation in the Elicitation of the Oxidative Burst in Cultured Soybean Cells. Chandra S, Low PS. Proc. Natl. Acad. Sci. USA 92:4120-3 (1995).

  292. Control of Erythrocyte Metabolism by Redox-Regulated Tyrosine Phosphatases and Kinases. Low PS, Kiyatkin A, Li Q, Harrison M. Protoplasma 184:196-202 (1995).

  293. Delivery of Antisense Oligodeoxyribonucleotides against the Human Epidermal Growth Factor Receptor into Cultured KB Cells using Folate-PEG-Liposomes. Wang S, Lee RJ, Gauchon G, Gorenstein DG, Low PS. Proc. Natl. Acad. Sci. USA 92:3318-22 (1995).

  294. Folate-Mediated Tumor Cell Targeting of Liposome-Entrapped Doxorubicin in vitro. Lee RJ, Low PS. Biochim. Biophys. Acta 1233:134-44 (1995).

  295. Visualization of Elicitor Binding Loci at the Plant Cell Surface. Diekmann W, Herkt B, Low PS, Nürnberger T, Scheel D, Terschüren C, Robinson DG. Planta 195:126-37 (1994).

  296. Calmodulin Modulates Protein 4.1 Binding to Human Erythrocyte Membranes. Lombardo CR, Low PS. Biochim. Biophys. Acta 1196:139-44 (1994).

  297. Comparison of the Oxidative Burst Signaling Pathways of Plants and Human Neutrophils. Low PS, Dwyer SC. Plant Responses to Environmental Stress, pp. 75-87 (1994).

  298. Endocytosis in Plants. Low PS, Chanda S. Annu. Rev. Plant Physiol. Plant Mol. Biol. 45:609-31 (1994).

  299. Selective Targeting of Malignant Cells with Cytotoxin-Folate Conjugates. Leamon CP, Low PS. J. Drug Targeting 2:101-12 (1994).

  300. Phosphorylation of Human Erythrocyte Band 3 by Endogenous p72syk*. Harrison ML, Isaacson CC, Burg DL, Geahlen RL, Low PS. J. Biol. Chem. 269:955-9 (1994).

  301. Delivery of Liposomes into Cultured KB Cells Via Folate Receptor-Mediated Endocytosis. Lee RJ, Low PS. J. Biol. Chem. 269:3198-204 (1994).

  302. Calorimetric Evidence for Allosteric Subunit Interactions Associated with Inhibitor Binding to Band 3 Transporters. Van Dort HM, Low PS, Cordes KA, Scopfer LM, Salhany JM. J. Biol. Chem. 269:59-61 (1994).

  303. Non-random Association of Free Iron with Membranes of Sickle and b-thalassemic Erythrocytes. Repka T, Shalev O, Reddy R, Yuan J, Rachmilewitz EA, Low PS, Hebbel RP. Blood 82:3204-10 (1993).

  304. Senescence of Canine Biotinylated Erythrocytes: Increased Autologous Immunoglobulin Binding Occurs on Erythrocytes Aged In Vivo for 104 to 110 Days. Christian JA, Rebar AH, Boon GD, Low PS. Blood 82:3469-73 (1993).

  305. Phospholipase C Activation During Elicitation of the Oxidative Burst in Cultured Plant Cells. Legendre L, Yueh YG, Crain R, Haddock N, Heinstein PF, Low PS. J. Biol. Chem. 268:24559-63 (1993).

  306. Cytotoxicity of Folate-Pseudomonas Exotoxin Conjugates Towards Tumor Cells: Contribution of Translocation Domain. Leamon CP, Pastan I, Low PS. J. Biol. Chem. 268:24847-54 (1993).

  307. Endocytosis of Folate-protein Conjugates: Ultrastructural Localization in KB Cells. Turek JJ, Leamon CP, Low PS. J. Cell Sci. 106:423-30 (1993).

  308. Regulation  of Glycolysis Via Reversible Enzyme Binding to the Membrane Protein, Band 3. Low PS, Rathinavelu R, Harrison M. J. Biol. Chem. 268:14627-31 (1993).

  309. Regulation of Linkages Between the Erythrocyte Membrane and its Skeleton by 2,3-diphosphoglycerate. Moriyama R, Lombardo CR, Workman RF, Low PS. J. Biol. Chem. 268:10990-6 (1993).

  310. Independent Elicitation of the Oxidative Burst and Phytoalexin Formation in Cultured Plant Cells. Davis D, Merida J, Legendre L, Low PS, Heinstein PF. Phytochemistry 32:607-11 (1993).

  311. Membrane Folate Binding Proteins are Responsible for the Folate-Protein Conjugate Endocytosis into Cultured Cells. Leamon CP, Low PS. Biochem. J. 291:855-60 (1993).

  312. Characterization of the Oligogalacturonide-Induced Oxidative Burst in Cultured Soybean Cells. Legendre L, Rueter S, Heinstein P, Low PS. Plant Physiol. 102:233-40 (1993).

  313. Characterization of the Autologous Antibodies that Opsonize Erythrocytes with Clustered Integral Membrane Proteins. Turrini F, Mannu F, Arese P, Yuan J, Low PS. Blood 81:3146-52 (1993).

  314. Comparison of Elicitor and Vitamin Receptor-Mediated Endocytosis in Cultured Soybean Cells. Low PS, Legendre L, Heinstein PF, Horn MA. J. Exp. Botany 44:269-74 (1993).

  315. The Effect of Mild Oxidants on Glycolysis in Human Erythrocytes. Harrison ML, Rathinavelu P, Arese P, Geahlen RL, Low PS. Biochem J. 283:622-3 Part 2 (1992)

  316. Structural and Functional Characterization of Band 3 from Southeast Asian Ovalocytes. Moriyama R, Ideguchi H, Lombardo CR, Van Dort HM, Low PS. J. Biol. Chem. 267:25792-7 (1992).

  317. Cytotoxicity of Momordin-Folate Conjugates in Cultured Human Cells. Leamon CP, Low PS. J. Biol. Chem. 267:24966-71 (1992).

  318. Induction of Secondary Metabolite-Phytoalexin Formation in Plant Cell Suspension Cultures. Heinstein P, Horn M, Davis D, Low PS. Secondary Metal Biosynthesis & Metabolism (eds. Ptroski RJ and McCormick SP) NY, p. 189-195 (1992).

  319. An Efficient Method for Conjugation of Thiamine to Proteins. Jayamani M, Low PS.  Bioorganic and Med. Chem. Lett. 2:1007-12 (1992).

  320. Evidence for Participation of GTP-binding Proteins in Elicitation of the Rapid Oxidative Burst in Cultured Soybean Cells. Legendre L, Heinstein PF, Low PS. J. Biol. Chem. 267:20140-7 (1992).

  321. Band 3: Calorimetry, Cytoskeletal Associations, Role in Metabolic Regulation, and Role in Aging. Low PS. Progress in Cell Research, (eds. E. Bamberg and H. Passow) Elsevier Science Publishers B.V., Amsterdam, Vol. 2, chap. 21, pp. 219-225 (1992).

  322. Expression, Purification and Characterization of Functional Dimeric Cytoplasmic Domain of Human Erythrocyte Band 3 in E. coli. Wang CC, Badylak JA, Lux SE, Moriyama R, Dixon JE, Low PS. Protein Science 1:1206-14 (1992).

  323. Resealing of Protein Tyrosine Kinase Substrates Into Human Erythrocytes by Rapid Freezing and Thawing in Liquid Nitrogen. Harrison M, Isaacson C, Rathinavelu P, Low PS. The Use of Resealed Erythrocytes as Carriers and Bioreactors, (eds. M. Magnani and J.R. DeLoach), Plenum Publ. Co.: New York, pp 111-118 (1992).

  324. Enhancement of Phytoalexin Accumulation in Cultured Plant Cells by Oxalate. Davis DA, Tsao D, Seo JH, Emery A, Low PS, Heinstein P. Phytochem. 31:1603-7 (1992).

  325. Epitope Mapping by a Method that Requires No Amino Acid Sequence Information. Yuan J, Low PS. Anal. Biochem. 205:179-82 (1992).

  326. Localization of the Protein 4.1 Binding Site on the Cytoplasmic Domain of Erythrocyte Membrane Band 3. Lombardo CR, Willardson BM, Low PS. J. Biol. Chem.  267:9540-6 (1992).

  327. Isolation, Characterization and Immunoprecipitation Studies of Immune Complexes from Membranes of b-Thalassemic Erythrocytes. Yuan J, Kannan R, Shinar E, Rachmilewitz EA, Low PS. Blood 79:3007-13 (1992).

  328. Characterization of Parameters Influencing Receptor-Mediated Endocytosis in Cultured Soybean Cells. Horn MA, Heinstein PF, Low PS. Plant Physiol. 98:673-9 (1992).

  329. Effect of Elicitation and Changes in Extracellular pH on the Cytoplasmic and Vacuolar pH of Suspension Cultured Soybean Cells. Horn M, Meadows R, Apostol I, Jones CR, Gorenstein DG, Heinstein PF,  Low PS. Plant Physiol. 98:680-6 (1992).

  330. Clustering of Integral Membrane Proteins of the Human Erythrocyte Membrane Stimulates Autologous IgG Binding, Complement Deposition and Phagocytosis. Turrini F, Arese P, Yuan J, Low PS. J. Biol. Chem. 266:23611-17 (1991).

  331. Isolation and Partial Characterization of Antibody- and Globin-Enriched Complexes from Membranes of Dense Human Erythrocytes. Kannan R, Yuan J, Low PS. Biochem. J. 278:57-62 (1991).

  332. Role of Hemoglobin Denaturation and Band 3 Clustering in Initiating Red Cell Removal. Low PS. "Red Cell Aging" (ed. M. Magnani), Plenum Press: New York, Adv. Exp. Med. Biol. 307:173-183 (1991).

  333. Delivery of Macromolecules into Living Cells: A Method that Exploits Folate Receptor Endocytosis. Leamon CP, Low PS. Proc. Natl. Acad. Sci. USA 88:5572-76 (1991).

  334. Immobilized Artificial Membrane Chromatography. Chae WG, Luo C, Rhee DM, Lombardo CR, Low PS, Pidgeon C. Modern Phytochemical Methods (eds. N.H. Fischer et al.) Plenum Press: NY, Chap. 5, pp. 149-174 (1991).

  335. Membrane Protein Crystallization: Observations and Use of Short Chain Phospholipids as Amphiphiles. Eisele JL, Keller T, K`nig N, Stauffer N, Rosenbusch JP, Low PS. Journal of Crystal Growth 110:96-102 (1991).

  336. Contribution of the Band 3-Ankyrin Interaction to Erythrocyte Membrane Mechanical Stability. Low PS, Willardson BM, Mohandas N, Rossi M, Shohet S. Blood 77:1581-6 (1991).

  337. Role of Band 3 Tyrosine Phosphorylation in Regulation of Erythrocyte Glycolysis. Harrison ML, Rathinavelu P, Arese P, Geahlen RL, Low PS.  J. Biol. Chem. 266:4106-11 (1991).

  338. Biotin-Mediated Delivery of Exogeneous Macromolecules into Soybean Cells. Horn MA, Heinstein PF, Low PS. Plant Physiol. 93:1492-6 (1990).

  339. Kinetics and Regulation of the Ankyrin-Band 3 Interaction of the Human Red Blood Cell Membrane. Thevenin BJM, Low PS. J. Biol. Chem. 265:16166-72 (1990).

  340. Extracellular Control of Erythrocyte Metabolism Mediated by a Cytoplasmic Tyrosine Kinase. Low PS, Geahlen RL, Mehler E, Harrison ML. Biomed. Biochim. Acta 49:135-40 (1990).

  341. Secondary Product Formation and Transmembrane Signaling in Plant Cells. Apostol I, Horn M, Davis D, Low PS, Heinstein P. Highlights of Modern Biochemistry (eds. A. Kotyk, J. Skoda, V. Paces and V. Kostka) VSP International Science Publishers, Zeist 1989, pp. 463-73, (1990).

  342. The Other Functions of Erythrocyte Membrane Band 3. Low PS, Willardson BM, Thevenin B, Kannan R, Mehler E, Geahlen RL, Harrison, ML. Anion Transport Protein of the Red Blood Cell Membrane, (eds. N. Hamasaki and M.L. Jennings), Springer Verlag, pp. 103-18 (1989).

  343. Receptor-Mediated Endocytosis in Plant Cells. Horn M, Heinstein PF, Low PS. The Plant Cell 1:1003-9 (1989).

  344. Effect of Hemoglobin Denaturation on Membrane Structure and IgG Binding: Role in Red Cell Aging. Low PS, Kannan R. The Red Cell: Seventh Ann Arbor Conference (ed. G. Brewer,) A.R. Liss: New York, pp. 525-52 (1989).

  345. Effect of Age of Cell Suspension Cultures on Susceptibility to a Fungal Elicitor. Apostol I, Low PS, Heinstein P. Plant Cell Reports 7:692-95 (1989).

  346. Identification and Partial Characterization of the Denaturation Transition of the Light Harvesting Complex II of Spinach Chloroplast Membranes. Smith KA, Ardelt BK, Huner NPA, Krol M, Myscich E, Low PS. Plant Physiol. 90:492-9 (1989).

  347. Identification and Partial Characterization of the Denaturation Transition of the Photosystem II Reaction Center of Spinach Chloroplast Membranes. Smith KA, Low PS. Plant Physiol. 90:575-81 (1989).

  348. Localization  of  the  Ankyrin  Binding Site on Erythrocyte Membrane Protein, Band 3. Willardson BM, Thevenin BJM, Harrison ML, Kuster WM, Benson MD, Low PS. J. Biol. Chem. 264:15893-9 (1989).

  349. The Redox State of Cysteines 201 and 317 of the Erythrocyte Anion Exchanger Is Critical for Ankyrin Binding. Thevenin BJM, Willardson BM, Low PS. J. Biol. Chem. 264:15886-92 (1989).

  350. Fatty Acid Composition of Lipids Which Copurify with Band 3. Maneri LR, Low PS.  Biochem. Biophys. Res. Comm. 159:1012-19 (1989).

  351. Rapid Stimulation of an Oxidative Burst During Elicitation of Cultured Plant Cells: Role in Defense and Signal Transduction. Apostol I, Heinstein P, Low PS. Plant Physiol. 90:109-16 (1989).

  352. Interaction of Native and Denatured Hemoglobins with Band 3: Consequences for Erythrocyte Structure and Function. Low PS. Red Blood Cell Membranes, (eds. P. Agre and P. Parker) Marcel Dekker, Inc., New York, pp. 237-260 (1989).

  353. Elicitor-Induced pH Changes in Cultured Soybean Cells. Apostol I, Low PS, Heinstein PF. J. Cell. Biochem. 12C:260 (1988).

  354. Structural Stability of the Erythrocyte Anion Transporter, Band 3, in Different Lipid Environments: a Differential Scanning Calorimetric Study. Maneri LR, Low PS. J. Biol. Chem. 263:16170-8 (1988).

  355. Isolation and Characterization of the Hemichrome-Stabilized Membrane Protein Aggregates from Sickle Erythrocytes: Major Site of Autologous Antibody Binding. Kannan R, Labotka R, Low PS. J. Biol. Chem. 263:13766-73 (1988).

  356. Immunocytochemical Localization of Band 3 Protein in the Rat Collecting Duct. Verlander JW, Madsen KM, Low PS, Allen DP, Tisher CC. Amer. J. Physiol. 255:F115-25 (1988).

  357. Interaction of Amphiphiles with Integral Membrane Proteins: Structural Destabilization of the Anion Transport Protein of the Erythrocyte Membrane by Fatty Acids, Fatty Alcohols, and Fatty Amines. Gruber HJ, Low PS. Biochim. Biophys. Acta. 944:414-24 (1988).

  358. In Vivo Low Temperature-Induced Decrease in 3-Transhexadecenoic Acid Influences Oligomerization of LHCII. Williams JP, Huner NPA, Krol M, Maissan E, Low PS, Roberts D, Thompson JE. Proc. VIIth Int. Congress Photosynth.(1987).

  359. Band 3 and Ankyrin Homologues Are Present in Eye Lens: Evidence for All Major Erythrocyte Membrane Components in Same Non-Erythroid Cell. Allen DP, Low PS, Dola A, Maisel H. Biochem Biophys Res Commun 149:266-75 (1987).

  360. Low Temperature Development Induces a Specific Decrease in trans-Î3-Hexadecenoic Acid Content which Influences LHCII Organization. Huner NPA, Krol M, Willians JP, Maissan E, Low PS, Roberts D, Thompson JE. Plant Physiol. 84:12-18 (1987).

  361. Inhibition of Elicitor-Induced Phytoalexin Formation in Cotton and Soybean Cells by Citrate. Apostol I, Low PS, Heinstein P, Stipanovic RD, Altman DW. Plant. Physiol. 84:1276-80 (1987).

  362. Tyrosine Phosphorylation of Band 3 Inhibits Peripheral Protein Binding. Low PS, Allen DP, Zioncheck TF, Chari P, Willardson BM, Geahlen RL, Harrison ML. J. Biol. Chem. 262:4592-6 (1987).

  363. Partial Characterization of the Copolymerization Reaction of Erythrocyte Membrane Band 3 with Hemichromes. Waugh SM, Walder JA, Low PS. Biochemistry 26:1777-83 (1987).

  364. Signal Transduction Across Plasma Membranes of Cultured Cells. Low PS, Heinstein PF. J. Cell. Biochem. 10B:29 (1986).

  365. Structure and Function of the Cytoplasmic Domain of Band 3: Center of Erythrocyte Membrane-Peripheral Protein Interactions. Low PS. Biochem. Biophys. Acta 864:145-67 (1986).

  366. Identification of the Soluble Coupling Factor Transition in Calorimetric Scans of Chloroplast Membranes. Smith KA, Ardelt BK, Low PS. Biochemistry 25:7099-105 (1986).

  367. Heinz Bodies Induce Clustering of Band 3, Glycophorin and Ankyrin in Sickle Cell Erythrocytes. Waugh SM, Willardson BM, Kannan R, Lobotka RJ, Low PS. J. Clin. Invest. 78:1155-60 (1986).

  368. Elicitor Stimulation of the Defense Response in Cultured Plant Cells Monitored by Fluorescent Dyes. Low PS, Heinstein PF. Arch. Biochem. Biophys. 249:472-9 (1986).

  369. The Redox Centers of Xanthine Oxidase are on Independent Structural Domains of the Enzyme. Nichols MB, Low PS. Arch. Biochem. Biophys. 250:488-97 (1986).

  370. Detection of Protein Kinase Activity in Sodium Dodecyl Sulfate - Polyacrylamide Gels. Geahlen RL, Anostario M Jr, Low PS, Harrison M. Anal. Biochem. 153:151-8 (1986).

  371. Possible Mechanism of Regulation of Membrane-cytoskeletal Interactions in Erythrocytes. Low PS, Appell KC. Contractile Proteins in Muscle and Non-Muscle Cells, (eds. E.E. Alia, N. Arena, and M.A. Russo), Praeger Scientific: New York. pp. 383-392, (1985).

  372. Identification and Partial Characterization of Xanthine Oxidase Transitions of the Milk Fat Globule Membrane. Burnier RC, Low PS. Arch. Biochem. Biophys. 240:60-9 (1985).

  373. Molecular Basis of the Biological Compatibility of Nature's Osmalytes. Low PS. Transport Processes, Iono- and Osmoregulation (eds. R. Giles and M. Gilles-Baillien), Springer-Verlag: Berlin, pp. 469-77 (1985).

  374. The Role of Hemoglobin Denaturation and Band 3 Clustering in Red Blood Cell Aging. Low PS, Waugh SM, Zinke K, Drenckhahn D. Science 227:531-3 (1985).

  375. Turnip Yellow Mosaic Virus and its Empty Capsid Have Thermal Stabilities with Opposite pH Dependence: Differential Scanning Calorimetry and 31P NMR Studies. Viruclachalem R, Low PS, Argos P, Markley JL. Virology 146:213-20 (1985).

  376. Hemichrome Binding to Band 3: Nucleation of Heinz Bodies on the Erythrocyte Membrane. Waugh SM, Low PS. Biochemistry 24:34-9 (1985).

  377. Characterization of Reversible Conformational Equilibrium of the Cytoplasmic Domain of Erythrocyte Membrane Band 3. Low PS, Westfall MA, Allen DP, Appell KC. J. Biol. Chem. 259:13070-6 (1984).

  378. The Interaction of Hemoglobin with the Cytoplasmic Domain of Band 3 of the Human Erythrocyte Membrane. Walder JA, Chatterjee R, Steck TL, Low PS, Musso GF, Kaiser ET, Rogers PH, Arnone A. J. Biol. Chem. 259:10238-46 (1984).

  379. T and B Lymphocytes Express Distinct Tyrosine Protein Kinases. Harrison M, Low PS, Geahlen RT. J. Biol. Chem. 259:9348-50 (1984).

  380. Identification of Immunoreactive Forms of Human Erythrocyte Band 3 in Nonerythroid Cells. Drenckhahn D, Zinke K, Schaver U, Appell KC, Low PS. Eur. J. Cell Biol. 34:144-50 (1984).

  381. Distinct Tyrosine Protein Kinases are Expressed by T and B Lymphocytes. Harrison ML, Low PS, Geahlen RL. Fed. Proc. 43:1468 (1984).

  382. Search for an Endotherm in Chloroplast Lamellar Membranes Associated with Chilling-Inhibition of Photosynthesis. Low PS, Cramer WA, Ort D, Whitmarsh J. Arch. Biochem. Biophys. 231:336-44 (1984).

  383. Differential Scanning Calorimetry of Milk Fat Globule Membranes. Burnier RC, Low PS. Fed. Proc. 42:1773 (1983).

  384. Differential Scanning Calorimetry of Milk Fat Globule Membranes. Appell KC, Low PS. Biochim. Biophys. Acta. 690:243-50 (1982).

  385. Anesthetic-Ion Channel Interactions: The Effect of Lidocaine on the Stability  and Transport Properties of the Membrane-Spanning Domain of Band 3. Davio SR, Low PS. Arch. Biochem. Biophys. 218:421-8 (1982).

  386. Characterization of the Calorimetric C Transition of the Human Erythrocyte Membrane. Davio SR, Low PS. Biochemistry 21:3585-93 (1982).

  387. Evidence for Restricted Oligosaccharide Mobility at the Erythrocyte Membrane Surface: A Fluorescence Study. Low PS, Cramer WA, Abraham G, Bone R, Ferguson-Seagall M. Arch. Biochem. Biophys. 214:675-80 (1982).

  388. Evaluation of the Structural Interdependence of the Membrane-Spanning and Cytoplasmic Domains of Band 3. Appell KC, Low PS. Biochemistry 21:2151-7, (1982).

  389. Partial Structural Characterization of the Cytoplasmic Domain of the Erythrocyte Membrane Protein, Band 3. Appell KC, Low PS. J. Biol. Chem. 256:11104-11 (1981).

  390. In vitro Promotion by Auxins of Divalent Ion Release From Soybean Membranes. Buckhout TJ, Young KA, Low PS, Morre DJ. J. Plant Physiol. 68:512-5 (1981).

  391. Effect of pH on the Cytoplasmic Domain of the Human Erythrocyte Membrane Protein, Band 3. Low PS, Appell KC. Fed. Proc. 40:1192 (1981)..

  392. Lateral Diffusion of Glycophorin Reconstituted into Phospholipid Multibilayers. Wu ES, Low PS, Webb WW. Biophys. J. 33:109a (1981).

  393. The Effect of Anesthetic Charge on Anesthetic-Phospholipid Interactions. Davio SR, Low PS. Biochim. Biophys. Acta 644:157-64, (1981).

  394. Differential Scanning Calorimetry of Chloroplast Membranes: Identification of an Endothermic Transition Associated with the Water-Splitting Complex of Photosystem II. Cramer WA, Whitmarsh J, Low PS. Biochemistry 20:157-62 (1981).

  395. Differential Scanning Calorimetry of Chloroplast Membranes. Cramer WA, Low PS, Selman BR, Whitmarsh J, Widger W. Proc. 5th Int. Conf. Photosynth., (ed. G. Akoyunoglou), pp. 121-129 (1981).

  396. Differential Scanning Calorimetry of Chloroplast Membranes: Identification and Partial Characterization of the A Transition. Whitmarsh CJ, Cramer WA, Low PS. Fed. Proc. 39:1023 (1980).

  397. Response of Isolated Plant Membranes to Auxins: Calcium Release. Buckhout TJ, Young KA, Morre DJ, Low PS. Botanical Gaz. 141:418-21 (1980).

  398. Colvalent Labeling of Specific Membrane Carbohydrate Residues with Fluorescent Probes. Abraham G, Low PS. Biochem. Biophys. Acta 597:285-91 (1980).

  399. Calcium Displacement by Local Anestetics: Dependence on pH and Anesthetic Charge. Low PS, Lloyd DH, Stein TM, Rogers JA III. J. Biol. Chem. 254:4119-25 (1979).

  400. Specific Fluorescence Labeling of Erythrocyte Membrane Proteins. Abraham G, Low PS. Fed. Proc. 38:357 (1979).

  401. Calcium Modification of the Anion Transport Mechanism in Red Blood Cells. Gunn RB, Frohlich O, Macintrye JD, Low PS. Biophys. J. 25:106a (1979).

  402. The Effects of Anion Transport Inhibitors on Structural Transitions in Erythrocyte Membranes. Snow JW, Brandts JF, Low PS. Biochem. Biophys. Acta 512:579-91 (1978).

  403. Protein Hydration Changes During Catalysis: An Important Contribution to the Properties of Enzyme Catalyzed Reactions. Low PS. Symp. Biol. Hungarica 21:217-47 (1978).

  404. Specific Cation Modulation of Anion Transport Across the Human Erythrocyte Membrane. Low PS. Biochem. Biophys. Acta 514:264-73 (1978).

  405. Calcium-Anesthetic Interactions in the Erythrocyte Membrane. Low PS, Roger JA III. J. Supramol. Structures, Suppl. 2:211 (1978).

  406. The Interaction of Adenine Nucleotides with the Red Cell Membrane: A Calorimetric Study. Low PS, Brandts JF. Arch. Biochem. Biophys. 190:640-6 (1978).

  407. Protein Water Binding Ability Correlates with Cellular Osmolarity. Low PS, Hoffman K, Swezey R, Somero GN. Experientia 34:314-5 (1978).

  408. Enzyme Hydration May Explain Catalytic Efficiency Differences Among Lactate Dehydrogenase Homologues. Somero GN, Low PS. Nature 266:276-8 (1977).

  409. Neutral Salt Effects on the Velocity and Activation Volume of the Lactate Dehydrogenase Reaction: Evidence for Enzyme Hydration Changes During Catalysis. Somero GN, Newbauer M, Low PS. Arch. Biochem. 181:438-46 (1977).

  410. Identification of a Structural Region Involved in Anion Transport. Snow JW, Brandts JF, Low PS. Fed. Proc. 36:896 (1977).

  411. Eurytolerant Proteins: Mechanisms for Extending the Environmental Tolerance Range of Enzyme-Ligand Interactions. Somero GN, Low PS. American Naturalist 111:527-38 (1977).

  412. Adaptation of Muscle Pyruvate Kinases to Environmental Temperatures and Pressures. Low PS, Somero GN. J. Exp. Zool. 198:1-12 (1976).

  413. Temperature: A "Shaping Force" in Enzyme Evolution. Somero GN, Low PS. Biochemical Society Symposium 41:33-42 (1976).

  414. Pressure Effects on Enzyme Structure and Function in vitro and in vivo. Low PS, Somero GN. Comp. Biochem. Physiol. 52B:67-74 (1975).

  415. Protein Hydration Changes During Catalysis: A New Mechanism to Account for Enzymic Rate-Enhancement and Ion Activation/Inhibition of Enzymes. Low PS, Somero GN. Proc. Natl. Acad. Sci. USA 72:3305-9 (1975).

  416. Activation Volumes in Enzymic Catalysis: Their Sources and Modification by Low Molecular Weight Solutes. Low PS, Somero GN. Proc. Natl. Acad. Sci. USA 72:3014-18 (1975).

  417. Temperature Adaptation of Enzymes: A Proposed Molecular Basis for the Different Catalytic Efficiencies of Enzymes from Ectotherms and Endotherms. Low PS, Somero GN. Comp. Biochem. Physiol. 49B:307-12 (1974).

  418. Bile Pigments in the Blood Serum of Fish from the Family Cottidae. Low, P. S.; Bada, J. L. Comp. Biochem. Physiol. 47A:411-18 (1974).

  419. Temperature Adaptation of Enzymes: Roles of the Free Energy, the Enthalpy, and the Entropy of Activation. Low, P. S.; Bada, J. L.; Somero, G. N. Proc. Nat. Acad. Sci. 70:430-2 (1973).