Philip S. Low

Next Generation Targeted Therapeutics

Radioligand therapies for cancer

Data derived from two of our recently designed radioligand therapies is shown below.  The first, a single dose of our FAP9-targeted 177Lu radiotherapy is shown to control PANC-1 tumors in mice, while the second, a single dose of three different versions of our bone metastasis-targeted 177Lu radiotherapy is shown to control prostate cancer metastases (implants) to the bone, as measured by serum PSA levels.  Several other radioligand therapies are also under development.

 

A single dose of our FAP9-targeted 177Lu radiotherapy is shown to control PANC-1 tumors in mice   A single dose of three different versions of our bone metastasis-targeted 177Lu radiotherapy are shown to control prostate cancer metastases to the bone.