Bioinorganic Research Group at Purdue

About Us
We are an interdisciplinary research group in the Department of Chemistry and Purdue Institute of Integrative Neuroscience to decipher the molecular mechanisms underlying the complex biological systems. We aim to investigate the roles of metal ions homeostasis in neurodegenerative diseases, design functional metalloproteins for biosynthetic, biotechnological and pharmaceutical applications, and elucidate the molecular basis of the mechanism of magnetoreception.
News
12/2025 - Our collaborative research paper, “Catalytic Enantioselective Cross-Nucleophile Coupling via Valence Tautomerism,” has been published in J. Am. Chem. Soc. We greatly appreciate the outstanding collaboration with the Liu Lab at the University of Pittsburgh and the Ngai Lab at Purdue. Link
11/2025 - We are excited to welcome new graduate students Chika Godson-Ahuaza and Fatimah Arabambi to the Tian Lab!
08/2025 - Congratulations to Maryam on being selected as a T32 Molecular Biophysics Training Program (MBTP) Fellow at Purdue!
07/2025 - The Tian Lab welcomes postdoctoral researcher Sheiny to the team. She will work on cryo-EM studies of membrane metalloproteins.
06/2025 - The Tian Lab is pleased to welcome new graduate student Angelina Loche to the group!
03/2025 - Congratulations to Andrew and Khai on their successful thesis defenses! They are the first Ph.D. graduates from the group—an exciting milestone for us all.
01/2025 - Congratulations to Eli and Andrew! Their research, titled "Secondary Sphere Interactions Modulate Peroxynitrite Scavenging by the E2 Domain of Amyloid Precursor Protein," has been published in Dalton Transactions! Link
11/2024 - Our collaborative research paper 'Enantioconvergent copper-catalysed difluoromethylation of alkyl halides' has been successfully published in Nat. Catal. A big congratulations to the entire team on this achievement! Link