Biomolecular NMR

Nikolai's publications

T. K. Mal; N. R. Skrynnikov; K. L. Yap; L. E. Kay; M. Ikura, Detecting protein kinase recognition modes of calmodulin by residual dipolar couplings in solution NMR. Biochemistry. 2002, 41, 12899-12906.

N. R. Skrynnikov; F. W. Dahlquist; L. E. Kay, Reconstructing NMR spectra of "invisible" excited protein states using HSQC and HMQC experiments. J. Am. Chem. Soc. 2002, 124, 12352-60.

D. M. Korzhnev; N. R. Skrynnikov; O. Millet; D. A. Torchia; L. E. Kay, An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates. J. Am. Chem. Soc. 2002 124, 10743-10753.

Skrynnikov NR, Millet O, Kay LE. Deuterium spin probes of side-chain dynamics in proteins. 2. Spectral density mapping and identification of nanosecond time-scale side-chain motions. J. Am. Chem. Soc. 2002, 124, 6449-6460.

O. Millet; D. R. Muhandiram; N. R. Skrynnikov; L. E. Kay, Deuterium spin probes of side-chain dynamics in proteins. 1. Measurement of five relaxation rates per deuteron in (13)C-labeled and fractionally (2)H-enriched proteins in solution. J. Am. Chem. Soc. 2002, 124, 6439-6448.

J. Boyd; N. R. Skrynnikov, Calculations of the contribution of ring currents to the chemical shielding anisotropy. J. Am. Chem. Soc. 2002, 124, 1832-1833.

M. Tollinger; N. R. Skrynnikov; F. A. Mulder; J. D. Forman-Kay; L. E. Kay, Slow dynamics in folded and unfolded states of an SH3 domain. J. Am. Chem. Soc. 2001, 123, 11341-11352.

L. W. Donaldson; N. R. Skrynnikov; W. Y. Choy; D. R. Muhandiram; B. Sarkar; J. D. Forman-Kay; L. E. Kay, Structural characterization of proteins with an attached ATCUN motif by paramagnetic relaxation enhancement NMR spectroscopy. J. Am. Chem. Soc. 2001, 123, 9843-9847.

N. R. Skrynnikov; F. A. Mulder; B. Hon; F. W. Dahlquist; L. E. Kay, Probing slow time scale dynamics at methyl-containing side chains in proteins by relaxation dispersion NMR measurements: application to methionine residues in a cavity mutant of T4 lysozyme. J. Am. Chem. Soc. 2001, 123, 4556-4566.

F. A. Mulder; N. R. Skrynnikov; B. Hon; F. W. Dahlquist; L. E. Kay, Measurement of slow (micros-ms) time scale dynamics in protein side chains by (15)N relaxation dispersion NMR spectroscopy: application to Asn and Gln residues in a cavity mutant of T4 lysozyme. J. Am. Chem. Soc. 2001, 123, 967-975.

P. M. Hwang; N. R. Skrynnikov; L. E. Kay, Domain orientation in beta-cyclodextrin-loaded maltose binding protein: diffusion anisotropy measurements confirm the results of a dipolar coupling study. J. Biomol. NMR. 2001, 20, 83-88.

J. Evenas; V. Tugarinov; N. R. Skrynnikov; N. K. Goto; R. Muhandiram; L. E. Kay, Ligand-induced structural changes to maltodextrin-binding protein as studied by solution NMR spectroscopy. J. Mol. Biol. 2001, 309, 961-974.

N. K. Goto; N. R. Skrynnikov; F. W. Dahlquist; L. E. Kay, What is the average conformation of bacteriophage T4 lysozyme in solution? A domain orientation study using dipolar couplings measured by solution NMR. J. Mol. Biol. 2001, 308, 745-764.

F. Separovic; N. R. Skrynnikov; B. C. Sanctuary, Selective on-resonance NMR irradiation of a dipolar doublet. Aust J Chem 2000, 53, (4), 355-361.

N. R. Skrynnikov; R. Konrat; D. R. Muhandiram; L. E. Kay, Relative orientation of peptide planes in proteins is reflected in carbonyl-carbonyl chemical shift anisotropy cross-correlated spin relaxation. J Am Chem Soc 2000, 122, (29), 7059-7071.

N. R. Skrynnikov; L. E. Kay, Assessment of molecular structure using frame-independent orientational restraints derived from residual dipolar couplings. J. Biomol. NMR. 2000, 18, 239-52.

G. A. Mueller; W. Y. Choy; N. R. Skrynnikov; L. E. Kay, A method for incorporating dipolar couplings into structure calculations in cases of (near) axial symmetry of alignment. J. Biomol. NMR. 2000, 18, 183-188.

N. R. Skrynnikov; N. K. Goto; D. Yang; W. Y. Choy; J. R. Tolman; G. A. Mueller; L. E. Kay, Orienting domains in proteins using dipolar couplings measured by liquid-state NMR: differences in solution and crystal forms of maltodextrin binding protein loaded with beta-cyclodextrin. J. Mol. Biol. 2000, 295, 1265-1273.

C. Scheurer; N. R. Skrynnikov; S. F. Lienin; S. K. Straus; R. Bruschweiler; R. R. Ernst, Effects of dynamics and environment on N-15 chemical shielding anisotropy in proteins. A combination of density functional theory, molecular dynamics simulation, and NMR relaxation. J Am Chem Soc 1999, 121, (17), 4242-4251.

N. R. Skrynnikov; R. R. Ernst, Detection of intermolecular chemical exchange through decorrelation of two-spin order. J. Magn. Reson. 1999, 137, 276-80.

B. Brutscher; N. R. Skrynnikov; T. Bremi, R. Brüschweiler; R. R. Ernst, Quantitative investigation of dipole-CSA cross-correlated relaxation by ZQ/DQ spectroscopy. J. Magn. Reson. 1998, 130, 346-51.

N. R. Skrynnikov; S. F. Lienin; R. Bruschweiler; R. R. Ernst, Efficient scalar spin relaxation in the rotating frame for matched radio-frequency fields. J Chem Phys 1998, 108, (18), 7662-7669.

N. R. Skrynnikov; T. N. Khazanovich; B. C. Sanctuary, Intermolecular relaxation involving coupled spin systems: a simplified approach to solvent induced relaxation. Mol Phys 1997, 91, (6), 977-992.

N. R. Skrynnikov; R. Bruschweiler, Comment on "Nuclear spin relaxation and non-ergodic quasi-equilibria". Chem Phys Lett 1997, 281, (1-3), 239-242.

N. R. Skrynnikov, Intermolecular translational-rotational contribution to nuclear-spin relaxation in liquids - Comment. Phys Rev A 1996, 53, (6), 4611-4612.

T. N. Khazanovich; N. R. Skrynnikov, External Random-Field Model for Intermolecular Spin Interactions - Accuracy Evaluation for the Coupled Relaxation of 2-Spin Molecules in a Pulse Responsive Solvent. J Phys Soc Jpn 1995, 64, (2), 631-635.

N. R. Skrynnikov; J. Zhou; B. C. Sanctuary, Classification of Cyclic Initial States and Geometric Phase for the Spin-J System. J Phys a-Math Gen 1994, 27, (18), 6253-6265.

N. R. Skrynnikov; B. C. Sanctuary, Geometric Phase in Nmr Interferometry Experiment. Mol Phys 1994, 83, (6), 1133-1144.