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James Tarpo Jr. and Margaret Tarpo
Department of Chemistry

Eric Dziekonski, Ph.D.

Eric Dziekonski

Senior Instrumentation Specialist

Specialties

  • Mass spectrometry instrumentation and method development (atm to E-12 torr)
  • Data acquisition and signal analysis
  • Graphical user interfaces, programming (MATLAB, Python, .NET), and hardware integration
  • Ion optical simulations (SIMION)
  • Prototyping and custom applications using microcontrollers
  • Instrument modifications, repair, and automation

Education

  • B.S. in Chemistry, SUNY Geneseo
  • Ph.D. in Chemistry, Purdue University

Projects

  • User Interface for calculating cosmogenic nuclide production rates in stony meteorites (https://www.eaps.purdue.edu/thermochronology/labshare.html)
  • User interface for the real-time capture and processing of 2D-MS/MS spectra
  • User interface to process raw data and report isotopic ratios generated via accelerator mass spectrometry in the thermochronology and PRIME lab’s at Purdue

Contact Information

BRWN 4151C
560 Oval Drive
West Lafayette, IN 47907
(765)494-4708
Email: edziekon@purdue.edu


Publications

Dziekonski, E. T. Two-Dimensional Tandem Mass Spectrometry in a Linear Quadrupole Ion Trap Using Consecutive Product Ion Sweeps. Int. J. Mass Spectrom. 2025, Submitted.

Fritz, J. M.; Carrick, I. J., Ellin, N. R., Dziekonski, E. T.; McLuckey, S. A. Demonstration of a nested electrostatic linear ion trap for flexibility in selecting analyzer figures-of-merit. Int. J. Mass Spectrom., 2025, 518, 117511.

Le, M. P.; Zhu, Y.; Dziekonski, E. T.; Holden, D. T.; Gleich, D. F.; Cooks, R. G. Framework for De novo Sequencing of Peptide Mixtures via Network Analysis and Two-Dimensional Tandem Mass Spectrometry. ChemRxiv, 2025, 10.26434/chemrxiv-2025-83d8x.

Dziekonski, E. T.; Cooks, R. G. Implementation of Automatic Gain Control for Two-Dimensional Tandem Mass Spectrometry in a Linear Quadrupole Ion Trap. Int. J. Mass Spectrom. 2025, Submitted.

Huang, K. H.; Chen, K.; Morato, N. M.; Sams, T. C.; Dziekonski, E. T.; Cooks, R. G. High-Throughput Microdroplet-Based Synthesis using Automated Array-to-Array Transfer. Chem. Sci.. 2025, 16, 7544-7550.

Hu, Y; Dziekonski, E.T.; Wang, D. M., Gonzalez, L. E.; Cooks, R. G. Rapid Identification of Phenolics in Mixtures by Two-Dimensional Tandem Mass Spectrometry with Microdroplet Accelerated Derivatization Reactions. Analysis & Sensing, 2024, 4, e202300081.

Sams, T. C.; Ying, S. E.; Edwards, M. Q.; Dziekonski, E. T.; Cooks, R. G. Rapid Screening of Secondary Plant Metabolites using Two-dimensional Tandem Mass Spectrometry. Analysis & Sensing, 2024, e202400103.

Le, M. T.; Holden, D. T.; Dziekonski, E. T.; Manheim, J. M.; Iyer, K.; Cooks, R. G. Two-Dimensional Tandem Mass Spectrometry for Biopolymer Structural Analysis. Angew. Chem. 2024, 136, e202315904.

Gonzalez, L. E.; Snyder, D. T.; Casey, H.; Hu, Y.; Wang, D. M.; Guetzloff, M.; Huckaby, N.; Dziekonski, E. T.; Wells, J. M.; Cooks, R. G. Machine-Learning Classification of Bacteria Using Two-Dimensional Tandem Mass Spectrometry. Anal. Chem. 2023, 46, 17082-17088.

Qui, L.; Saha, M.; Kraft, S.; Dziekonski, E. T.; Welch, C. J.; Dai, Y.; Kaerner, A.; Cooks, R. G. Quantitative Determination of Water in Organic Liquid by Ambient Mass Spectrometry. Angew. Chem. Int. Ed. 2023, 62, e202310884.

Dziekonski, E. T.; Eakins, G. S.; Cooks, R. G. Enabling one-and two-dimensional mass spectrometry in a linear quadrupole ion trap. Int. J. Mass Spectrom. 2023, 491, 117099.

Dziekonski, E. T.; Sams, T. C.; Szalwinski, L. J.; Gonzalez, L. E.; Cooks, R. G. Automated Desorption Electrospray Ionization Two-Dimensional Tandem Mass Spectrometry: Instrumentation and Software for High Throughput Analysis. Int. J. Mass Spectrom. 2023, 486, 117023.

Gonzalez, L. E.; Szalwinski, L. J.; Sams, T. C.; Dziekonski, E. T.; Cooks, R. G. Metabolomic and Lipidomic Profiling of Bacillus Using Two-Dimensional Tandem Mass Spectrometry. Anal. Chem. 2022, 94 (48), 16838-16846.

Bhanot, J. S.; Fabijanczuk, K. C., Abdillahi, A. M.; Chao, H.; Pizzala, N. J.; Londry, F. A., Dziekonski, E. T.; Hager, J. W.; McLuckey, S. A. Metabolomic and Lipidomic Profiling of Bacillus Using Two-Dimensional Tandem Mass Spectrometry. Int. J. Mass Spectrom. 2022, 478, 116874.

Adhikari, S.; Dziekonski, E. T.; Londry, F. A.; McLuckey, S. A. Dipolar DC Induced Collisional Activation of Non-Dissociated Electron-Transfer Products. J. Mass Spectrom. 2019, 54, 459-465.

Foreman, D. J.; Dziekonski, E. T.; McLuckey, S. A. Maximizing Selective Cleavages at Aspartic Acid and Proline Residues for the Identification of Intact Proteins. J. Am. Soc. Mass Spectrom. 2018, 1-11.

Dziekonski, E. T.; Johnson, J. T.; Lee, K. W.; McLuckey, S. A. Determination of Collision Cross Sections Using a Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometer. J Am. Soc. Mass Spectrom. 2018, 29, 242-250.

Dziekonski, E. T. Development of the Fourier Transform Electrostatic Linear Ion Trap for the Analysis of Gas Phase Ions. (Doctoral Dissertation) Purdue University, 2017.

Dziekonski, E. T.; Johnson, J. T.; Lee, K. W.; McLuckey, S. A. Fourier-Transform MS and Closed-Path Multireflection Time-of-Flight MS Using and Electrostatic Linear Ion Trap.  Anal. Chem. 2017, 89, 10965-10972.

Dziekonski, E. T.; Johnson, J. T.; McLuckey, S. A. Utility of Higher Harmonics in Electrospray Ionization Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometry. Anal. Chem. 2017, 89, 4392-4397.

Jin, C.; Viidanoja, J.; Li, M.; Zhang, Y.; Ikonen, E.; Root, A.; Romanczyk, M.; Manheim, J.; Dziekonski, E. T.; Kenttamaa, H. I. Comparison of Atmospheric Pressure Chemical Ionization and Field Ionization Mass Spectrometry for the Analysis of Large Saturated Hydrocarbons. Anal. Chem. 2016, 88, 10592-10598.

DeBlase, A. F.; Dziekonski, E. T.; Hopkins, J. R.; Burke, N. L.; Sheng, H.; Kenttamaa, H. I.; McLuckey, S. A.; Zwier, T. S. Alkali Cation Chelation in Cold β-O-4 Tetralignol Complexes. J. Phys. Chem. A. 2016, 120, 7152-7166.

Dziekonski, E. T.; Johnson, J. T.; Hilger, R. T.; McIntyre, C. L.; Santini, R. E.; McLuckey, S. A. Voltage-Induced Frequency Drift Correction in Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometry Using Mirror-Switching. Int. J. Mass Spectrom. 2016, 410, 12-21.

Dziekonski, E. T.; Santini, R. E.; McLuckey, S. A. A Dual Detector Fourier Transform Electrostatic Linear Ion Trap Utilizing In-Trap Potential Lift. Int. J. Mass Spectrom. 2016, 405, 1-8. 

Hilger, R. T.; Dziekonski, E. T.; Santini, R. E.; McLuckey, S. A. Injecting electrospray ions into a Fourier transform electrostatic linear ion trap. Int. J. Mass Spectrom. 2015, 378, 281-287.

Clemons, K.; Wiley, R.; Waverka, K.; Fox, J.; Dziekonski, E.; Verbeck, G. Direct Analyte-Probed Nanoextraction Coupled to Nanospray Ionization Mass Spectrometry of Drug Residues from Latent Fingerprints. Journal of Forensic Sciences 2013, 58, 875-880.