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Aloke Kumar Bera, Ph.D.

Senior Laboratory Specialist

Education

Ph D: Biophysics and Molecular Biology, University of Calcutta, India
MS:    Biophysics, University of Kalyani, India
BS:     Physics, University of Calcutta, India

Contact Information

BRWN 3154A
560 Oval Drive
West Lafayette, IN 47907
(765) 496-2216 (Cell: 765-491-4394)
Email: bera@purdue.edu


Publications

  1. Bera, A., Wu, R., Harrison, S., CORNELISSEN, C. N., Chazin, W., Noinaj, N. (2022), TdfH selectively binds metal-loaded tetrameric calprotectin for zinc import: Communications Biology 5 (1), 1-6
  2. Kammerman, MT., Bera, A., Wu, R., Harrison, S.A., Maxwell, C.N., Lundquist, K., Noinaj, N., Chazin, W.J., and Cornelissen, C. N. (2020), Molecular Insight into TdfH-Mediated Zinc Piracy from Human Calprotectin by Neisseria gonorrhoeae: mBio. May 26;11(3): e00949-20
  3. Langevin, S, Bowen R, Reisen W, Andrade C, Ramey W, Maharaj P, Anishchenko M, Kenney J, Duggal N, Bera AK, Sanders T, Bosco-Lauth A, Smith JL, Kuhn R, and Brault AC. (2014) Host competence and helicase activity differences exhibited by West Nile viral variants expressing NS3- 249 amino acid polymorphisms. Plos One 9: e 100802
  4. Bera, A. K., Sedlak, M., Khan, A., and Ho, W. Y.N. (2011) A genetic overhaul of Saccharomyces cerevisiae 424A(LNH-ST) to improve xylose fermentation, J. Ind Microbiol Biotechnol. 38: 617- 626.
  5. Bera, A. K., Sedlak, M., Khan, A., and Ho, W. Y.N. (2010) Establishment of L-arabinose fermentation in glucose/xylose co-fermenting Saccharomyces cerevisiae 424A(LNH-ST) by genetic engineering, Appl Microbiol Biotechnol. 87: 1803-1811.
  6. Bera, A. K., Kuhn, R. J., and Smith, J. L. (2007) Functional characterization of cis- and transprotease activity of five flavivirus NS2B/NS3 complex. J Biol. Chem. 282: 12883-92.
  7. Wu, J., Bera, A. K., Kuhn, R. J., and Smith, J. L. (2005) Structure of the flavivirus helicase: implications for catalytic activity, protein interactions and proteolytic processing, J. Virology 79: 10268-10277.
  8. Bera, A. K., Zhu, J., Zalkin, H., and Smith, J. L. (2003) Functional Dissection of the Bacillus pur Operator Site, J. Bacteriol. 185: 4099-109.
  9. *Hannemann, F., *Bera, A. K., Fisher, B., Lisurek, M., and Bernhardt, R. (2002) Unfolding and conformational studies on bovine adrenodoxin probed by engineered intrinsic tryptophan fluorescence, Biochem. 41: 11008-16 (*equal contribution).
  10. Iametti, S., Bera, A. K. Vecchio, G., Grinberg, A., Bernhardt, R., and Bonomi, F. (2001) GroELassisted refolding of adrenodoxin during chemical cluster insertion, Eur. J. Biochem. 268: 2421- 2429.
  11. Bera, A. K., Chen, S., Smith, J. L., and Zalkin, H. (2000) Temperature-dependent function of glutamine phosphoribosylamidotransferase ammonia channel and coupling with glycinamide ribonucleotide synthetase in a hyperthermophyle, J. Bacteriol. 182: 3734-3739.
  12. Bera, A. K., Smith, J. L., and Zalkin, H. (2000) Duel role for the glutamine phosphoribosyl-amidotransferase: Interdomain signaling and Intermediate channeling, J Biol. Chem. 275: 7975-7979.
  13. Bera, A. K., and Bernhardt, R. (1999) GroEL-assisted and unassisted refolding of mature and precursor adrenodoxin: the role of the precursor sequence, Arch. Biochem. Biophys.367: 89-94.
  14. Bera, A. K., Chen, S., Smith, J. L., and Zalkin, H. (1999) Interdomain signalling in Gluta-mine Phosphori-bosylpyrophosphate Amidotransferase, J. Biol. Chem. 274: 36498-504.
  15. Bera, A. K., Gringberg, A., and Bernhardt, R. (1999) A Step Towards Understanding the Folding Mechanism of Bovine Adrenodoxin, Arch. Biochem. Biophys. 361: 315-322.
  16. Iametti, S., Bera, A. K., Vecchio, G., Grinberg, A., Bernhardt, R., F Bonomi, F. Protein assisted refolding of adrenodoxin during chemical cluster insertion. J. Ing. Biochem, 74 (1-4), 175-175.
  17. Chakrabarti, A., Bera, A. K., Das, B., Chattopadhyay, S., Sarkar, D., and Dasgupta, C. (1999) Binding and conformation of denatured horseradish peroxidase during E. coli ribosome mediated folding, Current Sci. 76: 1235-1238.
  18. Das, B., Chattopadhyay, S., Bera, A. K., and Dasgupta, C. (1996) In vitro protein folding by ribosomes from Escherichia coli, wheat germ and rat liver: the role of the 50 S particle and its 23S rRNA, Eur. J. Biochem. 235: 613-621.
  19. Bera, A. K., Das, B., Chattopadhyay, S., and Dasgupta, C. (1994). Refolding of denatured restriction endonucleases with ribosomal preparations from Methanosarcina barkeri. Biochem. Mol. Biol. Internal. 32:315-323.
  20. Bera, A. K., Das, B., Chattopadhyay, S., and Dasgupta, C. (1994) Protein folding by ribosomes and its RNA, Current Sci. 66: 230-232.
  21. Chattopadhyay, S., Das, B., Bera, A. K., Dasgupta, D., and Dasgupta, C. (1994). Refolding of denatured lactate dehydrogenase by E. coli ribosome. Biochem. J. 300:717-721.
  22. Pain, S., Bera, A., Das. M., Das. B. N., and Banerjee, A. (1992) On structural aspect of peptidoglycan of bacterial cell wall with special attention on mycobacterial by computer modeling, Ind. J. Lepr. 64: 24-45.
  23. Bera, A., and Banerjee, A. (1989) Studies on lipid in mycobacterial cell wall, Ind. J. Lepr. 61: 143-150.