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Biochemistry Faculty 2015

Biochemistry

Purdue University’s Biochemistry core area offers leading-edge research programs for studies of biological systems. Our multidisciplinary programs encompass both fundamental and applied research, including:
  • Mechanisms of transport of nutrients and therapeutic agents across the cell membrane.
  • Integral membrane proteins involved in cancer and cancer treatment.
  • Signal transduction pathways that control cell shape and flexibility.
  • Development of novel chemical tools for drug discovery.
  • Chemical Genetic Dissection of Kinases and G-Proteins for Target Identification and Validation in Cancer and Neurodegenerative diseases.
  • Functional role of deubiquitinating enzymes in cellular pathways, particularly those implicated in neurodegenerative disorders including Alzheimer and Parkinson disease.
  • Development and application of NMR techniques for studies of proteins and complex forms of molecular motion.
  • Design and synthesis of receptor-targeted imaging and therapeutic agents for cancer, infectious and inflammatory diseases.
  • Targeting ligands to deliver covalently attached therapeutic and imaging agents to cancerous and other pathologic tissues.
  • Novel methods for the rapid detection and identification of pathogens that will prove critical in the detection of both biowarfare agents and naturally transmitted human pathogens.
  • Using structural tools and tools of biochemistry, cell and molecular biology, organic synthesis, and bioanalytical chemistry, to define the molecular mechanisms of substrate recognition by enzymes and membrane-associated proteins.
  • Development of tools in proteomics for discovery of molecular markers for cancer detection.
  • Development of tools in Bioinformatics for studies of chromatin structure and gene regulation.

Purdue University, West Lafayette, IN 47907 (765) 494-4600

Department of Chemistry, 560 Oval Drive, West Lafayette, Indiana 47907-2084 | Telephone: (765) 494-5200 | Fax: (765) 494-0239

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